IL92267A0 - 2(1h)-quinolinone compounds,processes for the preparation thereof and pharmaceutical compositions comprising the same - Google Patents
2(1h)-quinolinone compounds,processes for the preparation thereof and pharmaceutical compositions comprising the sameInfo
- Publication number
- IL92267A0 IL92267A0 IL92267A IL9226789A IL92267A0 IL 92267 A0 IL92267 A0 IL 92267A0 IL 92267 A IL92267 A IL 92267A IL 9226789 A IL9226789 A IL 9226789A IL 92267 A0 IL92267 A0 IL 92267A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- processes
- preparation
- pharmaceutical compositions
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888827189A GB8827189D0 (en) | 1988-11-21 | 1988-11-21 | 2(1h)-quinolinone compounds processes for preparation thereof & pharmaceutical composition comprising same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL92267A0 true IL92267A0 (en) | 1990-07-26 |
Family
ID=10647207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL92267A IL92267A0 (en) | 1988-11-21 | 1989-11-09 | 2(1h)-quinolinone compounds,processes for the preparation thereof and pharmaceutical compositions comprising the same |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4988698A (da) |
| EP (1) | EP0370381B1 (da) |
| JP (1) | JPH02167266A (da) |
| KR (1) | KR900007829A (da) |
| CN (1) | CN1042905A (da) |
| AT (1) | ATE122350T1 (da) |
| AU (1) | AU4454289A (da) |
| CA (1) | CA2003397A1 (da) |
| DE (1) | DE68922583T2 (da) |
| DK (1) | DK583089A (da) |
| FI (1) | FI895327A7 (da) |
| GB (1) | GB8827189D0 (da) |
| HU (1) | HUT52092A (da) |
| IL (1) | IL92267A0 (da) |
| NO (1) | NO894610L (da) |
| PT (1) | PT92318B (da) |
| ZA (1) | ZA898522B (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0696555B2 (ja) * | 1986-07-31 | 1994-11-30 | 大塚製薬株式会社 | カルボスチリル誘導体 |
| FR2637591B1 (fr) * | 1988-10-11 | 1992-10-23 | Synthelabo | Derives de quinoleinone, leur preparation et leur application en therapeutique |
| US5563142A (en) * | 1989-12-28 | 1996-10-08 | The Upjohn Company | Diaromatic substituted compounds as anti-HIV-1 agents |
| US5599930A (en) * | 1991-07-03 | 1997-02-04 | The Upjohn Company | Substituted indoles as anti-AIDS pharmaceuticals |
| FR2711992A1 (fr) * | 1993-11-03 | 1995-05-12 | Lipha | Nouveaux dérivé hétérocycliques, procédé de préparation et composition pharmaceutique les contenant. |
| US5814029A (en) * | 1994-11-03 | 1998-09-29 | Daig Corporation | Guiding introducer system for use in ablation and mapping procedures in the left ventricle |
| JPH11500123A (ja) * | 1995-02-15 | 1999-01-06 | ファルマシア・アンド・アップジョン・カンパニー | ＣＮＳおよび心臓病の治療のためのイミダゾ［１，２−ａ］ピリジン類 |
| US5938660A (en) * | 1997-06-27 | 1999-08-17 | Daig Corporation | Process and device for the treatment of atrial arrhythmia |
| US6251109B1 (en) * | 1997-06-27 | 2001-06-26 | Daig Corporation | Process and device for the treatment of atrial arrhythmia |
| US6013654A (en) * | 1997-08-14 | 2000-01-11 | Pharmacia & Upjohn Company | Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases |
| WO2000042213A1 (en) | 1999-01-13 | 2000-07-20 | The Research Foundation Of State University Of New York | A novel method for designing protein kinase inhibitors |
| EP1165013A4 (en) * | 1999-03-03 | 2002-08-07 | Merck & Co Inc | INHIBITORS OF PHENYL PROTEIN TRANSFERASE |
| US7005445B2 (en) | 2001-10-22 | 2006-02-28 | The Research Foundation Of State University Of New York | Protein kinase and phosphatase inhibitors and methods for designing them |
| WO2003035621A1 (en) | 2001-10-22 | 2003-05-01 | The Research Foundation Of State University Of New York | Protein kinase and phosphatase inhibitors, methods for designing them, and methods of using them |
| JP2005289816A (ja) * | 2002-05-14 | 2005-10-20 | Banyu Pharmaceut Co Ltd | ベンズイミダゾール誘導体 |
| CN1150176C (zh) * | 2002-05-22 | 2004-05-19 | 上海医药工业研究院 | 芳烷酮哌嗪衍生物及其应用 |
| WO2004022060A2 (en) | 2002-09-06 | 2004-03-18 | Janssen Pharmaceutica, N.V. | (1h-benzoimidazol-2-yl)-(piperazinyl)-methanone derivatives and related compounds as histamine h4-receptor antagonists for the treatment of inflammatory and allergic disorders |
| US7789877B2 (en) * | 2003-07-02 | 2010-09-07 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation catheter electrode arrangement |
| US7234225B2 (en) | 2003-09-22 | 2007-06-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Method for manufacturing medical device having embedded traces and formed electrodes |
| US7229437B2 (en) * | 2003-09-22 | 2007-06-12 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Medical device having integral traces and formed electrodes |
| US8147486B2 (en) * | 2003-09-22 | 2012-04-03 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Medical device with flexible printed circuit |
| US20060058383A1 (en) * | 2004-07-28 | 2006-03-16 | Peng Huang | Propyl 3-bromo-2-oxopropionate and derivatives as novel anticancer agents |
| EP2392571A3 (en) * | 2005-07-29 | 2012-03-14 | F. Hoffmann-La Roche AG | Indol-3-yl-carbonyl-piperidin and piperazin derivatives |
| US7838542B2 (en) | 2006-06-29 | 2010-11-23 | Kinex Pharmaceuticals, Llc | Bicyclic compositions and methods for modulating a kinase cascade |
| WO2008005908A2 (en) * | 2006-07-07 | 2008-01-10 | Forest Laboratories Holdings Limited | Pyridoimidazole derivatives |
| FR2925902B1 (fr) * | 2008-01-02 | 2011-01-07 | Sanofi Aventis | DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
| KR20130059400A (ko) * | 2010-08-25 | 2013-06-05 | (주)네오팜 | 신규한 헤테로고리 화합물 및 이를 이용한 염증성 질환 치료용 조성물 |
| US9428478B2 (en) | 2011-06-13 | 2016-08-30 | Emory University | Piperazine derivatives, compositions, and uses related thereto |
| CN102633717B (zh) * | 2012-03-30 | 2013-11-20 | 西南大学 | N-乙酰-喹啉-2(1h)酮类化合物及其制备方法和应用 |
| CN102875465A (zh) * | 2012-09-14 | 2013-01-16 | 上海大学 | 7-溴异喹啉的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5777676A (en) * | 1980-10-31 | 1982-05-15 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| ES2053480T3 (es) * | 1986-07-31 | 1994-08-01 | Otsuka Pharma Co Ltd | Un procedimiento para preparar un derivado de carboestirilo. |
-
1988
- 1988-11-21 GB GB888827189A patent/GB8827189D0/en active Pending
-
1989
- 1989-11-08 ZA ZA898522A patent/ZA898522B/xx unknown
- 1989-11-09 FI FI895327A patent/FI895327A7/fi not_active Application Discontinuation
- 1989-11-09 AU AU44542/89A patent/AU4454289A/en not_active Abandoned
- 1989-11-09 IL IL92267A patent/IL92267A0/xx unknown
- 1989-11-10 JP JP1293455A patent/JPH02167266A/ja active Pending
- 1989-11-13 US US07/434,256 patent/US4988698A/en not_active Expired - Fee Related
- 1989-11-15 PT PT92318A patent/PT92318B/pt not_active IP Right Cessation
- 1989-11-16 AT AT89121183T patent/ATE122350T1/de not_active IP Right Cessation
- 1989-11-16 EP EP89121183A patent/EP0370381B1/en not_active Expired - Lifetime
- 1989-11-16 DE DE68922583T patent/DE68922583T2/de not_active Expired - Fee Related
- 1989-11-20 KR KR1019890016803A patent/KR900007829A/ko not_active Withdrawn
- 1989-11-20 NO NO89894610A patent/NO894610L/no unknown
- 1989-11-20 CN CN89108752A patent/CN1042905A/zh active Pending
- 1989-11-20 DK DK583089A patent/DK583089A/da not_active Application Discontinuation
- 1989-11-20 CA CA002003397A patent/CA2003397A1/en not_active Abandoned
- 1989-11-21 HU HU896035A patent/HUT52092A/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU896035D0 (en) | 1990-02-28 |
| JPH02167266A (ja) | 1990-06-27 |
| DK583089A (da) | 1990-05-22 |
| AU4454289A (en) | 1990-05-24 |
| PT92318A (pt) | 1990-05-31 |
| FI895327A0 (fi) | 1989-11-09 |
| HUT52092A (en) | 1990-06-28 |
| DE68922583D1 (de) | 1995-06-14 |
| EP0370381B1 (en) | 1995-05-10 |
| ZA898522B (en) | 1990-08-29 |
| EP0370381A3 (en) | 1991-06-26 |
| CA2003397A1 (en) | 1990-05-21 |
| EP0370381A2 (en) | 1990-05-30 |
| US4988698A (en) | 1991-01-29 |
| ATE122350T1 (de) | 1995-05-15 |
| GB8827189D0 (en) | 1988-12-29 |
| CN1042905A (zh) | 1990-06-13 |
| NO894610L (no) | 1990-05-22 |
| FI895327A7 (fi) | 1990-05-22 |
| DK583089D0 (da) | 1989-11-20 |
| KR900007829A (ko) | 1990-06-02 |
| DE68922583T2 (de) | 1995-10-05 |
| NO894610D0 (no) | 1989-11-20 |
| PT92318B (pt) | 1995-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC | Change of name of proprietor(s) |