IL92670A - Monoclonal antibodies that bind to an antigenic unit in the region of the alpha chain of the antigen receptor found on T cells and pharmaceuticals that contain them - Google Patents

Monoclonal antibodies that bind to an antigenic unit in the region of the alpha chain of the antigen receptor found on T cells and pharmaceuticals that contain them

Info

Publication number
IL92670A
IL92670A IL9267089A IL9267089A IL92670A IL 92670 A IL92670 A IL 92670A IL 9267089 A IL9267089 A IL 9267089A IL 9267089 A IL9267089 A IL 9267089A IL 92670 A IL92670 A IL 92670A
Authority
IL
Israel
Prior art keywords
cells
cell
monoclonal antibody
tcr
antibody
Prior art date
Application number
IL9267089A
Other languages
English (en)
Hebrew (he)
Original Assignee
T Cell Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by T Cell Sciences Inc filed Critical T Cell Sciences Inc
Priority to IL10874189A priority Critical patent/IL108741A/en
Priority to IL10874289A priority patent/IL108742A/en
Priority to IL10874294A priority patent/IL108742A0/xx
Publication of IL92670A publication Critical patent/IL92670A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL9267089A 1988-12-15 1989-12-13 Monoclonal antibodies that bind to an antigenic unit in the region of the alpha chain of the antigen receptor found on T cells and pharmaceuticals that contain them IL92670A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL10874189A IL108741A (en) 1988-12-15 1989-12-13 Active monoclonal antibodies with defined regions of the T cell antibody receptor
IL10874289A IL108742A (en) 1988-12-15 1989-12-13 Active monoclonal antibodies with defined regions of the T cell antibody receptor
IL10874294A IL108742A0 (en) 1988-12-15 1994-02-22 Monoclonal antibodies reactive with defined regions of the T cell antigen receptor

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28451188A 1988-12-15 1988-12-15
US34318989A 1989-04-25 1989-04-25
US07/449,692 US5223426A (en) 1988-12-15 1989-12-11 Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor

Publications (1)

Publication Number Publication Date
IL92670A true IL92670A (en) 1995-03-30

Family

ID=27403469

Family Applications (2)

Application Number Title Priority Date Filing Date
IL9267089A IL92670A (en) 1988-12-15 1989-12-13 Monoclonal antibodies that bind to an antigenic unit in the region of the alpha chain of the antigen receptor found on T cells and pharmaceuticals that contain them
IL10874194A IL108741A0 (en) 1988-12-15 1994-02-22 Monoclonal antibodies reactive with defined regions of the t cell antigen receptor

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL10874194A IL108741A0 (en) 1988-12-15 1994-02-22 Monoclonal antibodies reactive with defined regions of the t cell antigen receptor

Country Status (7)

Country Link
US (5) US5223426A (fr)
EP (2) EP0867189A3 (fr)
JP (1) JPH03502762A (fr)
KR (1) KR0174540B1 (fr)
AU (2) AU643195B2 (fr)
IL (2) IL92670A (fr)
WO (1) WO1990006758A1 (fr)

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US5223426A (en) * 1988-12-15 1993-06-29 T Cell Sciences, Inc. Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor
JPH06507384A (ja) * 1991-01-22 1994-08-25 ザ　イミューン　レスポンス　コーポレイション 特定のｔ細胞群による病理的応答により生じる疾患に対するワクチン投与および方法

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JPH03502762A (ja) 1991-06-27
EP0867189A2 (fr) 1998-09-30
EP0867189A3 (fr) 1999-03-03
US5223426A (en) 1993-06-29
WO1990006758A1 (fr) 1990-06-28
AU643195B2 (en) 1993-11-11
US6048526A (en) 2000-04-11
AU4472793A (en) 1993-11-18
IL108741A0 (en) 1994-05-30
AU651931B2 (en) 1994-08-04
US6171799B1 (en) 2001-01-09
EP0404912A1 (fr) 1991-01-02
AU4838290A (en) 1990-07-10
US5976533A (en) 1999-11-02
US5980892A (en) 1999-11-09
KR900702007A (ko) 1990-12-05
KR0174540B1 (ko) 1999-02-01
EP0404912A4 (en) 1991-01-30

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