IL93225A - (4-amino-2,6-dimethylphenylsulphonyl)- nitromethane or salts thereof, process for their preparation and pharmaceutical compositions containing them - Google Patents

(4-amino-2,6-dimethylphenylsulphonyl)- nitromethane or salts thereof, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL93225A
IL93225A IL9322590A IL9322590A IL93225A IL 93225 A IL93225 A IL 93225A IL 9322590 A IL9322590 A IL 9322590A IL 9322590 A IL9322590 A IL 9322590A IL 93225 A IL93225 A IL 93225A
Authority
IL
Israel
Prior art keywords
nitromethane
amino
salt
pharmaceutically acceptable
compound
Prior art date
Application number
IL9322590A
Other languages
English (en)
Other versions
IL93225A0 (en
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/306,676 external-priority patent/US5153227A/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of IL93225A0 publication Critical patent/IL93225A0/xx
Publication of IL93225A publication Critical patent/IL93225A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/36Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40Y being a hydrogen or a carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
IL9322590A 1989-02-06 1990-01-30 (4-amino-2,6-dimethylphenylsulphonyl)- nitromethane or salts thereof, process for their preparation and pharmaceutical compositions containing them IL93225A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/306,676 US5153227A (en) 1987-08-06 1989-02-06 Phenylsulfonyl nitromethanes as aldose reductase inhibitors

Publications (2)

Publication Number Publication Date
IL93225A0 IL93225A0 (en) 1990-11-05
IL93225A true IL93225A (en) 1994-05-30

Family

ID=23186342

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9322590A IL93225A (en) 1989-02-06 1990-01-30 (4-amino-2,6-dimethylphenylsulphonyl)- nitromethane or salts thereof, process for their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
EP (1) EP0408713B1 (de)
JP (1) JP3056245B2 (de)
KR (1) KR910700232A (de)
AT (1) ATE89550T1 (de)
AU (1) AU630151B2 (de)
CA (1) CA2026003A1 (de)
DE (1) DE69001650T2 (de)
DK (1) DK0408713T3 (de)
ES (1) ES2055416T3 (de)
FI (1) FI904891L (de)
GB (1) GB2227745B (de)
GR (1) GR1000423B (de)
HU (1) HU206674B (de)
IE (1) IE63463B1 (de)
IL (1) IL93225A (de)
NO (1) NO173822C (de)
NZ (1) NZ232293A (de)
PT (1) PT93064B (de)
RU (2) RU1817776C (de)
WO (1) WO1990008761A1 (de)
ZA (1) ZA90674B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016980D0 (en) * 1990-08-02 1990-09-19 Ici Plc Amidobenzenes
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
FR2757509B1 (fr) * 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
US5932765A (en) * 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them
KR100571614B1 (ko) * 1997-10-20 2006-04-17 다이닛본 스미토모 세이야꾸 가부시끼가이샤 속용성 의약 조성물
ES2206868T3 (es) * 1998-07-15 2004-05-16 Merck Sante Comprimidos que comprenden una combinacion de metformin glibenclamida.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions
DE3727468A1 (de) * 1987-08-18 1989-03-02 Kolbenschmidt Ag Verbundgleitlager

Also Published As

Publication number Publication date
EP0408713B1 (de) 1993-05-19
HU901209D0 (en) 1991-03-28
ATE89550T1 (de) 1993-06-15
GR1000423B (el) 1992-07-30
FI904891A7 (fi) 1991-08-07
NO904335L (no) 1990-12-05
EP0408713A1 (de) 1991-01-23
GR900100069A (en) 1991-06-28
HUT55354A (en) 1991-05-28
AU630151B2 (en) 1992-10-22
ES2055416T3 (es) 1994-08-16
CA2026003A1 (en) 1990-08-07
KR910700232A (ko) 1991-03-14
NZ232293A (en) 1992-06-25
GB2227745A (en) 1990-08-08
ZA90674B (en) 1990-10-31
DK0408713T3 (da) 1993-06-14
HU206674B (en) 1992-12-28
GB2227745B (en) 1992-08-05
PT93064A (pt) 1990-08-31
DE69001650D1 (de) 1993-06-24
NO173822B (no) 1993-11-01
RU1817776C (ru) 1993-05-23
AU4953890A (en) 1990-08-24
PT93064B (pt) 1995-12-29
NO904335D0 (no) 1990-10-05
RU2034834C1 (ru) 1995-05-10
JPH03505215A (ja) 1991-11-14
JP3056245B2 (ja) 2000-06-26
IL93225A0 (en) 1990-11-05
NO173822C (no) 1994-02-09
DE69001650T2 (de) 1993-09-02
GB9002373D0 (en) 1990-04-04
IE900288L (en) 1990-08-06
IE63463B1 (en) 1995-04-19
FI904891A0 (fi) 1990-10-04
WO1990008761A1 (en) 1990-08-09
FI904891L (fi) 1991-08-07

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Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void