NO173822C - Analogifremgangsmaate for fremstilling av den terapeutisk aktive forbindelse (4-amino-2,6-dimetylfenylsulfonyl)nitrometan og farmasoeytisk akseptable salter derav - Google Patents

Analogifremgangsmaate for fremstilling av den terapeutisk aktive forbindelse (4-amino-2,6-dimetylfenylsulfonyl)nitrometan og farmasoeytisk akseptable salter derav

Info

Publication number
NO173822C
NO173822C NO904335A NO904335A NO173822C NO 173822 C NO173822 C NO 173822C NO 904335 A NO904335 A NO 904335A NO 904335 A NO904335 A NO 904335A NO 173822 C NO173822 C NO 173822C
Authority
NO
Norway
Prior art keywords
dimethylphenylsulfonyl
nitromethane
amino
preparation
pharmaceutically acceptable
Prior art date
Application number
NO904335A
Other languages
English (en)
Norwegian (no)
Other versions
NO173822B (no
NO904335D0 (no
NO904335L (no
Inventor
David Robert Brittain
Steven Paul Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Linda Slater
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/306,676 external-priority patent/US5153227A/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of NO904335D0 publication Critical patent/NO904335D0/no
Publication of NO904335L publication Critical patent/NO904335L/no
Publication of NO173822B publication Critical patent/NO173822B/no
Publication of NO173822C publication Critical patent/NO173822C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40—Y being a hydrogen or a carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
NO904335A 1989-02-06 1990-10-05 Analogifremgangsmaate for fremstilling av den terapeutisk aktive forbindelse (4-amino-2,6-dimetylfenylsulfonyl)nitrometan og farmasoeytisk akseptable salter derav NO173822C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/306,676 US5153227A (en) 1987-08-06 1989-02-06 Phenylsulfonyl nitromethanes as aldose reductase inhibitors
PCT/GB1990/000150 WO1990008761A1 (en) 1989-02-06 1990-02-02 Phenylsulphone derivatives

Publications (4)

Publication Number Publication Date
NO904335D0 NO904335D0 (no) 1990-10-05
NO904335L NO904335L (no) 1990-12-05
NO173822B NO173822B (no) 1993-11-01
NO173822C true NO173822C (no) 1994-02-09

Family

ID=23186342

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904335A NO173822C (no) 1989-02-06 1990-10-05 Analogifremgangsmaate for fremstilling av den terapeutisk aktive forbindelse (4-amino-2,6-dimetylfenylsulfonyl)nitrometan og farmasoeytisk akseptable salter derav

Country Status (21)

Country Link
EP (1) EP0408713B1 (de)
JP (1) JP3056245B2 (de)
KR (1) KR910700232A (de)
AT (1) ATE89550T1 (de)
AU (1) AU630151B2 (de)
CA (1) CA2026003A1 (de)
DE (1) DE69001650T2 (de)
DK (1) DK0408713T3 (de)
ES (1) ES2055416T3 (de)
FI (1) FI904891L (de)
GB (1) GB2227745B (de)
GR (1) GR1000423B (de)
HU (1) HU206674B (de)
IE (1) IE63463B1 (de)
IL (1) IL93225A (de)
NO (1) NO173822C (de)
NZ (1) NZ232293A (de)
PT (1) PT93064B (de)
RU (2) RU1817776C (de)
WO (1) WO1990008761A1 (de)
ZA (1) ZA90674B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
GB9016980D0 (en) * 1990-08-02 1990-09-19 Ici Plc Amidobenzenes
FR2757509B1 (fr) * 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
US5932765A (en) * 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them
CZ299018B6 (cs) * 1997-10-20 2008-04-02 Dainippon Sumitomo Pharma Co., Ltd. Rychlerozpustný farmaceutický prípravek
DE69818444T2 (de) * 1998-07-15 2004-05-06 Merck Santé Tabletten enthaltend eine Kombination von Glibenclamid und Metformin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions
DE3727468A1 (de) * 1987-08-18 1989-03-02 Kolbenschmidt Ag Verbundgleitlager

Also Published As

Publication number Publication date
HUT55354A (en) 1991-05-28
PT93064B (pt) 1995-12-29
IE63463B1 (en) 1995-04-19
GB2227745A (en) 1990-08-08
FI904891A7 (fi) 1991-08-07
JP3056245B2 (ja) 2000-06-26
RU2034834C1 (ru) 1995-05-10
NO173822B (no) 1993-11-01
GR1000423B (el) 1992-07-30
NO904335D0 (no) 1990-10-05
WO1990008761A1 (en) 1990-08-09
DE69001650T2 (de) 1993-09-02
GB9002373D0 (en) 1990-04-04
EP0408713B1 (de) 1993-05-19
NZ232293A (en) 1992-06-25
FI904891A0 (fi) 1990-10-04
NO904335L (no) 1990-12-05
GR900100069A (en) 1991-06-28
HU206674B (en) 1992-12-28
PT93064A (pt) 1990-08-31
AU630151B2 (en) 1992-10-22
ATE89550T1 (de) 1993-06-15
CA2026003A1 (en) 1990-08-07
IL93225A (en) 1994-05-30
ZA90674B (en) 1990-10-31
EP0408713A1 (de) 1991-01-23
RU1817776C (ru) 1993-05-23
GB2227745B (en) 1992-08-05
DE69001650D1 (de) 1993-06-24
JPH03505215A (ja) 1991-11-14
IE900288L (en) 1990-08-06
FI904891L (fi) 1991-08-07
IL93225A0 (en) 1990-11-05
KR910700232A (ko) 1991-03-14
DK0408713T3 (da) 1993-06-14
ES2055416T3 (es) 1994-08-16
AU4953890A (en) 1990-08-24
HU901209D0 (en) 1991-03-28

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