IL93397A - Pancreatic islet cell antigen protein or peptides, their preparation by molecular cloning, their use in the diagnosis of insulin dependent diabetes mellitus and pharmaceutical compositions comprising said antigens - Google Patents
Pancreatic islet cell antigen protein or peptides, their preparation by molecular cloning, their use in the diagnosis of insulin dependent diabetes mellitus and pharmaceutical compositions comprising said antigensInfo
- Publication number
- IL93397A IL93397A IL93397A IL9339790A IL93397A IL 93397 A IL93397 A IL 93397A IL 93397 A IL93397 A IL 93397A IL 9339790 A IL9339790 A IL 9339790A IL 93397 A IL93397 A IL 93397A
- Authority
- IL
- Israel
- Prior art keywords
- islet cell
- antigens
- peptides
- diagnosis
- preparation
- Prior art date
Links
- 210000004153 islets of langerhan Anatomy 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000010369 molecular cloning Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 208000035408 type 1 diabetes mellitus 1 Diseases 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31254389A | 1989-02-17 | 1989-02-17 | |
| US44170389A | 1989-12-04 | 1989-12-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL93397A0 IL93397A0 (en) | 1990-11-29 |
| IL93397A true IL93397A (en) | 1997-06-10 |
Family
ID=26978437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL93397A IL93397A (en) | 1989-02-17 | 1990-02-14 | Pancreatic islet cell antigen protein or peptides, their preparation by molecular cloning, their use in the diagnosis of insulin dependent diabetes mellitus and pharmaceutical compositions comprising said antigens |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0383129B1 (pt) |
| JP (1) | JP2858467B2 (pt) |
| AT (1) | ATE122394T1 (pt) |
| AU (1) | AU626636B2 (pt) |
| CA (1) | CA2010275C (pt) |
| DE (1) | DE69019190T2 (pt) |
| DK (1) | DK0383129T3 (pt) |
| ES (1) | ES2072928T3 (pt) |
| FI (1) | FI103730B1 (pt) |
| GR (1) | GR3017019T3 (pt) |
| IE (1) | IE66997B1 (pt) |
| IL (1) | IL93397A (pt) |
| NO (1) | NO306996B1 (pt) |
| PT (1) | PT93166B (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5645998A (en) | 1988-12-13 | 1997-07-08 | University Of Florida Research Foundation | Methods and compositions for the early detection and treatment of insulin dependent diabetes mellitus |
| US6001360A (en) * | 1988-12-13 | 1999-12-14 | University Of Florida | Method and compositions for early detection and treatment of insulin dependent diabetes mellitus |
| JPH02200700A (ja) * | 1989-01-30 | 1990-08-08 | Shionogi & Co Ltd | 新規reg蛋白質 |
| US5175085A (en) * | 1990-02-20 | 1992-12-29 | Board Of Regents, The University Of Texas System | Methods and compositions for diagnosing autoimmune insulin dependent diabetes mellitus |
| US5744327A (en) * | 1990-02-20 | 1998-04-28 | Board Of Regents, The University Of Texas System | Methods for producing insulin in response to non-glucose secretagogues |
| US5427940A (en) * | 1991-06-03 | 1995-06-27 | Board Of Regents, The University Of Texas System | Engineered cells producing insulin in response to glucose |
| WO1992004632A1 (en) | 1990-09-07 | 1992-03-19 | The Regents Of The University Of California | Methods for the diagnosis and treatment of diabetes |
| US5674978A (en) * | 1990-09-21 | 1997-10-07 | The Regents Of The University Of California | Peptides derived from glutamic acid decarboxylase |
| US5998366A (en) * | 1990-09-21 | 1999-12-07 | The Regents Of The University Of California | Method for ameliorating glutamic acid decarboxylase associated autoimmune disorders |
| US6682906B1 (en) | 1990-09-21 | 2004-01-27 | The Regents Of The University Of California | Cloned glutamic acid decarboxylase |
| WO1992006105A1 (en) * | 1990-10-02 | 1992-04-16 | Trigen Incorporated | Antibodies and methods for diagnosis and treatment of diabetes |
| JPH06508030A (ja) * | 1991-05-15 | 1994-09-14 | ザイモジェネティクス,インコーポレイティド | ヒトすい島グルタミン酸デカルボキシラーゼ自己抗原のクローニング及び発現 |
| US5792656A (en) * | 1991-06-03 | 1998-08-11 | Board Of Regents, The University Of Texas System | Methods of preparing genetically engineered cells that produce insulin in response to glucose |
| WO1993016725A1 (en) * | 1992-02-27 | 1993-09-02 | The Board Of Trustees Of The Leland Stanford Junior University | Early antigen for autoimmune diabetes |
| US5200318A (en) * | 1992-05-13 | 1993-04-06 | Miles Inc. | Diagnosis of IDDM with a panel of immunoreagents |
| WO1996038479A1 (fr) * | 1995-05-30 | 1996-12-05 | Fujisawa Pharmaceutical Co., Ltd. | Procede de diagnostic du diabete sucre insulino-dependant et kit de diagnostic |
| AU1989097A (en) | 1996-03-06 | 1997-09-22 | University Of Washington | Diabetes mellitus 37 kd autoantigen protein-tyrosine phosphatase |
| AU7159898A (en) * | 1997-04-25 | 1998-11-24 | Genetics Institute Inc. | Secreted proteins and polynucleotides encoding them |
| CN110244051A (zh) * | 2019-07-05 | 2019-09-17 | 许昌学院 | 一种用于糖尿病的多组分标记免疫检测系统 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE53862T1 (de) * | 1982-01-22 | 1990-06-15 | Cetus Corp | Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel. |
| IL69686A (en) * | 1983-09-11 | 1988-03-31 | Yeda Res & Dev | Compositions containing cell membrane proteins and process for their preparation |
| WO1986007464A1 (en) * | 1985-06-14 | 1986-12-18 | Genetic Systems Corporation | Methods for identifying alleles associated with increased risk of diabetes |
| CA1327162C (en) * | 1987-04-09 | 1994-02-22 | Board Of Trustees Of The Leland Stanford Junior University (The) | Method for prophylactically treating an individual for an autoimmune disease |
| EP0359783B2 (en) * | 1987-06-24 | 2002-04-17 | Autoimmune, Inc. | Treatment of autoimmune diseases by oral administration of autoantigens |
-
1990
- 1990-02-01 NO NO900474A patent/NO306996B1/no not_active IP Right Cessation
- 1990-02-03 DE DE69019190T patent/DE69019190T2/de not_active Expired - Lifetime
- 1990-02-03 AT AT90102179T patent/ATE122394T1/de not_active IP Right Cessation
- 1990-02-03 EP EP90102179A patent/EP0383129B1/en not_active Expired - Lifetime
- 1990-02-03 ES ES90102179T patent/ES2072928T3/es not_active Expired - Lifetime
- 1990-02-03 DK DK90102179.0T patent/DK0383129T3/da active
- 1990-02-14 IL IL93397A patent/IL93397A/xx not_active IP Right Cessation
- 1990-02-15 PT PT93166A patent/PT93166B/pt not_active IP Right Cessation
- 1990-02-15 FI FI900759A patent/FI103730B1/fi active IP Right Grant
- 1990-02-16 JP JP2034016A patent/JP2858467B2/ja not_active Expired - Lifetime
- 1990-02-16 IE IE58990A patent/IE66997B1/en not_active IP Right Cessation
- 1990-02-16 AU AU49883/90A patent/AU626636B2/en not_active Expired
- 1990-02-16 CA CA002010275A patent/CA2010275C/en not_active Expired - Lifetime
-
1995
- 1995-08-02 GR GR950402141T patent/GR3017019T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE122394T1 (de) | 1995-05-15 |
| FI103730B (fi) | 1999-08-31 |
| AU4988390A (en) | 1990-08-23 |
| NO900474L (no) | 1990-08-20 |
| EP0383129A2 (en) | 1990-08-22 |
| EP0383129A3 (en) | 1991-07-31 |
| NO900474D0 (no) | 1990-02-01 |
| IE66997B1 (en) | 1996-02-21 |
| DE69019190T2 (de) | 1995-09-14 |
| JPH0347133A (ja) | 1991-02-28 |
| ES2072928T3 (es) | 1995-08-01 |
| PT93166A (pt) | 1990-08-31 |
| DE69019190D1 (de) | 1995-06-14 |
| DK0383129T3 (da) | 1995-10-09 |
| PT93166B (pt) | 1997-11-28 |
| JP2858467B2 (ja) | 1999-02-17 |
| FI900759A0 (fi) | 1990-02-15 |
| CA2010275C (en) | 2000-08-29 |
| IL93397A0 (en) | 1990-11-29 |
| GR3017019T3 (en) | 1995-11-30 |
| CA2010275A1 (en) | 1990-08-17 |
| IE900589L (en) | 1990-08-17 |
| FI103730B1 (fi) | 1999-08-31 |
| NO306996B1 (no) | 2000-01-24 |
| EP0383129B1 (en) | 1995-05-10 |
| AU626636B2 (en) | 1992-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| HC | Change of name of proprietor(s) | ||
| KB | Patent renewed | ||
| EXP | Patent expired |