IL94664A - 4,5,5a,6-tetrahydro-3h-isoxyzolo (5, 4, 3-kl) acridine derivatives, a process for their preparation and pharmaceutical compositions containing them - Google Patents

4,5,5a,6-tetrahydro-3h-isoxyzolo (5, 4, 3-kl) acridine derivatives, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL94664A
IL94664A IL9466490A IL9466490A IL94664A IL 94664 A IL94664 A IL 94664A IL 9466490 A IL9466490 A IL 9466490A IL 9466490 A IL9466490 A IL 9466490A IL 94664 A IL94664 A IL 94664A
Authority
IL
Israel
Prior art keywords
compound
formula
loweralkyl
group
afford
Prior art date
Application number
IL9466490A
Other languages
English (en)
Other versions
IL94664A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL94664A0 publication Critical patent/IL94664A0/xx
Publication of IL94664A publication Critical patent/IL94664A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL9466490A 1989-06-09 1990-06-07 4,5,5a,6-tetrahydro-3h-isoxyzolo (5, 4, 3-kl) acridine derivatives, a process for their preparation and pharmaceutical compositions containing them IL94664A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/364,420 US4920117A (en) 1989-06-09 1989-06-09 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use

Publications (2)

Publication Number Publication Date
IL94664A0 IL94664A0 (en) 1991-04-15
IL94664A true IL94664A (en) 1994-11-11

Family

ID=23434459

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9466490A IL94664A (en) 1989-06-09 1990-06-07 4,5,5a,6-tetrahydro-3h-isoxyzolo (5, 4, 3-kl) acridine derivatives, a process for their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4920117A (da)
EP (1) EP0401779B1 (da)
JP (1) JPH089624B2 (da)
KR (1) KR0148365B1 (da)
AT (1) ATE122047T1 (da)
AU (1) AU619985B2 (da)
CA (1) CA2018564C (da)
DE (1) DE69019066T2 (da)
DK (1) DK0401779T3 (da)
ES (1) ES2072334T3 (da)
FI (1) FI902851A7 (da)
IE (1) IE67074B1 (da)
IL (1) IL94664A (da)
NO (1) NO902556L (da)
NZ (1) NZ233971A (da)
PT (1) PT94298B (da)
ZA (1) ZA904442B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine
US5236930A (en) * 1989-11-13 1993-08-17 Mitbushi Gas Chemical Company, Inc. Oxazopyrroloquinolines and use of oxazopyrroloquinolines
WO2003076419A1 (en) * 2002-03-08 2003-09-18 Japan Science And Technology Agency Isoxazole derivatives and process for producing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8314391D0 (en) * 1983-05-24 1983-06-29 Kefalas As Heterocyclic compounds
FR2566407B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine

Also Published As

Publication number Publication date
CA2018564C (en) 2002-11-12
DE69019066D1 (de) 1995-06-08
NO902556L (no) 1990-12-10
IE67074B1 (en) 1996-02-21
FI902851A0 (fi) 1990-06-07
ZA904442B (en) 1991-03-27
PT94298B (pt) 1997-01-31
IE902078L (en) 1990-12-09
JPH089624B2 (ja) 1996-01-31
EP0401779B1 (en) 1995-05-03
IL94664A0 (en) 1991-04-15
AU619985B2 (en) 1992-02-06
DE69019066T2 (de) 1995-10-19
DK0401779T3 (da) 1995-10-16
EP0401779A1 (en) 1990-12-12
PT94298A (pt) 1991-02-08
ES2072334T3 (es) 1995-07-16
NZ233971A (en) 1992-11-25
CA2018564A1 (en) 1990-12-09
NO902556D0 (no) 1990-06-08
US4920117A (en) 1990-04-24
KR910000744A (ko) 1991-01-30
JPH0324085A (ja) 1991-02-01
AU5691790A (en) 1990-12-13
KR0148365B1 (ko) 1998-11-02
ATE122047T1 (de) 1995-05-15
FI902851A7 (fi) 1990-12-10

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Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
MM9K Patent not in force due to non-payment of renewal fees