IL96407A0 - Diazine derivatives - Google Patents

Diazine derivatives

Info

Publication number
IL96407A0
IL96407A0 IL96407A IL9640790A IL96407A0 IL 96407 A0 IL96407 A0 IL 96407A0 IL 96407 A IL96407 A IL 96407A IL 9640790 A IL9640790 A IL 9640790A IL 96407 A0 IL96407 A0 IL 96407A0
Authority
IL
Israel
Prior art keywords
novel compounds
compounds
diazine derivatives
hypertension
manufacture
Prior art date
Application number
IL96407A
Other languages
English (en)
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898926211A external-priority patent/GB8926211D0/en
Priority claimed from GB909011348A external-priority patent/GB9011348D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of IL96407A0 publication Critical patent/IL96407A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Insulating Materials (AREA)
  • Vibration Prevention Devices (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
IL96407A 1989-11-20 1990-11-19 Diazine derivatives IL96407A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898926211A GB8926211D0 (en) 1989-11-20 1989-11-20 Diazine derivatives
GB909011348A GB9011348D0 (en) 1990-05-21 1990-05-21 Nitrogen heterocycles

Publications (1)

Publication Number Publication Date
IL96407A0 true IL96407A0 (en) 1991-08-16

Family

ID=26296233

Family Applications (1)

Application Number Title Priority Date Filing Date
IL96407A IL96407A0 (en) 1989-11-20 1990-11-19 Diazine derivatives

Country Status (17)

Country Link
US (1) US5126344A (de)
EP (1) EP0454831B1 (de)
JP (1) JPH04505161A (de)
KR (1) KR920701206A (de)
AT (1) ATE109481T1 (de)
AU (1) AU6733690A (de)
BG (1) BG60068B2 (de)
CA (1) CA2030240A1 (de)
DE (1) DE69011318T2 (de)
FI (1) FI913478A7 (de)
GB (1) GB9024730D0 (de)
HU (1) HUT58334A (de)
IE (1) IE903911A1 (de)
IL (1) IL96407A0 (de)
NZ (1) NZ236127A (de)
PT (1) PT95929A (de)
WO (1) WO1991007404A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0443983B1 (de) * 1990-02-19 1996-02-28 Ciba-Geigy Ag Acylverbindungen
GB9010394D0 (en) * 1990-05-09 1990-06-27 Ici Plc Heterocyclic compounds
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
GB9102804D0 (en) * 1991-02-11 1991-03-27 Ici Plc Heterocyclic derivatives
AU1625192A (en) * 1991-05-31 1992-12-03 Zeneca Limited Heterocyclic derivatives
JPH05213884A (ja) * 1991-06-14 1993-08-24 Upjohn Co:The 新規な４−アミノキノリン類およびこれを有効成分とする高血圧・鬱血性心不全の予防・治療剤
GB9113628D0 (en) * 1991-06-25 1991-08-14 Ici Plc Heterocyclic derivatives
GB9113626D0 (en) * 1991-06-25 1991-08-14 Ici Plc Heterocyclic compounds
US5246944A (en) * 1991-08-13 1993-09-21 Merck & Co., Inc. Quinoline angiotensin ii antagonists incorporating a substituted benzyl element
GB9121727D0 (en) * 1991-10-14 1991-11-27 Ici Plc Heterocyclic compounds
GB9202633D0 (en) * 1992-02-07 1992-03-25 Fujisawa Pharmaceutical Co Heterocyclic derivatives
TW297025B (de) * 1992-02-14 1997-02-01 Squibb & Sons Inc
GB2264710A (en) * 1992-03-04 1993-09-08 Merck & Co Inc Quinoline and azaquinoline angiotensin ii antagonists incorporating a substituted biphenyl element
WO1993017682A1 (en) * 1992-03-04 1993-09-16 Abbott Laboratories Angiotensin ii receptor antagonists
GB9211270D0 (en) * 1992-05-28 1992-07-15 Ici Plc Nitrogen compounds
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
CA2462289C (en) * 2001-10-04 2010-02-23 Nicholas D. Cosford Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5
AR037517A1 (es) * 2001-11-05 2004-11-17 Novartis Ag Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
EP2968439A2 (de) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Zusammensetzungen zur behandlung von magen-darm-störungen
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
WO2017013237A1 (en) 2015-07-23 2017-01-26 Institut Curie Use of a combination of dbait molecule and parp inhibitors to treat cancer
GB201519573D0 (en) 2015-11-05 2015-12-23 King S College London Combination
WO2018162439A1 (en) 2017-03-08 2018-09-13 Onxeo New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule
WO2019175132A1 (en) 2018-03-13 2019-09-19 Onxeo A dbait molecule against acquired resistance in the treatment of cancer
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
SMT202500447T1 (it) 2021-11-02 2026-01-12 Flare Therapeutics Inc Agonisti inversi di pparg e loro usi
WO2024261243A1 (en) 2023-06-21 2024-12-26 Hemispherian As Combination comprising a deoxycytidine derivative and a parp inhibitor for use in a method of treating hr proficient cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
DE3907937A1 (de) * 1989-03-11 1990-09-13 Basf Ag Substituierte 1,8-naphthylridine, verfahren zu ihrer herstellung und ihre verwendung als antidots
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives

Also Published As

Publication number Publication date
KR920701206A (ko) 1992-08-11
CA2030240A1 (en) 1991-05-21
FI913478A0 (fi) 1991-07-18
EP0454831B1 (de) 1994-08-03
EP0454831A1 (de) 1991-11-06
HU912485D0 (en) 1991-12-30
ATE109481T1 (de) 1994-08-15
FI913478A7 (fi) 1991-07-18
WO1991007404A1 (en) 1991-05-30
NZ236127A (en) 1993-08-26
US5126344A (en) 1992-06-30
HUT58334A (en) 1992-02-28
JPH04505161A (ja) 1992-09-10
AU6733690A (en) 1991-06-13
IE903911A1 (en) 1991-05-22
DE69011318D1 (de) 1994-09-08
BG60068B2 (bg) 1993-09-30
DE69011318T2 (de) 1994-12-01
PT95929A (pt) 1991-09-13
GB9024730D0 (en) 1991-01-02

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