IN2012DN00338A - - Google Patents

Download PDF

Info

Publication number
IN2012DN00338A
IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
Authority
IN
India
Prior art keywords
methods
relates
present
region containing
containing protein
Prior art date
Application number
Other languages
English (en)
Inventor
Soice Neil
Hubbard Dana
Zhang Yu
Harmzik James
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of IN2012DN00338A publication Critical patent/IN2012DN00338A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
IN338DEN2012 2009-08-07 2010-08-05 IN2012DN00338A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27370909P 2009-08-07 2009-08-07
PCT/US2010/044539 WO2011017514A1 (en) 2009-08-07 2010-08-05 Methods for purifying a target protein from one or more impurities in a sample

Publications (1)

Publication Number Publication Date
IN2012DN00338A true IN2012DN00338A (de) 2015-05-22

Family

ID=43544660

Family Applications (1)

Application Number Title Priority Date Filing Date
IN338DEN2012 IN2012DN00338A (de) 2009-08-07 2010-08-05

Country Status (9)

Country Link
US (1) US8536316B2 (de)
EP (1) EP2462157B1 (de)
JP (2) JP5791602B2 (de)
KR (1) KR101415660B1 (de)
CN (2) CN102574911B (de)
ES (1) ES2817802T3 (de)
IN (1) IN2012DN00338A (de)
SG (1) SG177577A1 (de)
WO (1) WO2011017514A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3237179B2 (ja) 1992-03-18 2001-12-10 栗田工業株式会社 排超純水中の過酸化水素の除去方法
WO2011090719A2 (en) * 2009-12-29 2011-07-28 Dr. Reddy's Laboratories Ltd. Protein purification by ion exchange
SG10201710439UA (en) 2010-05-25 2018-01-30 Genentech Inc Methods of purifying polypeptides
KR101627597B1 (ko) 2010-07-30 2016-06-08 이엠디 밀리포어 코포레이션 부직포 층
RU2018119112A (ru) 2011-05-27 2018-11-07 Эббви Байотекнолоджи Лтд. Композиции и способы на основе dac hyp
AU2012269240B2 (en) 2011-06-16 2016-01-21 Dpx Holdings B.V. Single unit chromatography antibody purification
BR112014000352A2 (pt) 2011-07-08 2017-02-14 Merck Sharp & Dohe Corp método de purificar uma proteína de fusão-fc, proteínas de fusão contendo fc purificada, tnfr:fc purificada, e tnfr:fc elevadamente purificada
CN103827134A (zh) 2011-07-20 2014-05-28 泽普泰恩股份有限公司 多肽分离方法
WO2013019889A2 (en) * 2011-08-01 2013-02-07 Avaxia Biologics, Inc. Bovine polyclonal antibody specific for human tnf
US9096648B2 (en) * 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
WO2013033517A1 (en) * 2011-09-01 2013-03-07 Human Genome Sciences, Inc. Viral clearance methods
EP2578286A1 (de) 2011-10-04 2013-04-10 Merck Patent GmbH Verfahren und Vorrichtung zur chromatographischen Aufreinigung
MX2014005330A (es) * 2011-11-02 2014-09-08 Genentech Inc Cromatografia de sobrecarga y elucion.
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN102492040B (zh) * 2011-12-29 2014-06-25 嘉和生物药业有限公司 一种抗her2或/和抗her3抗体蛋白的纯化方法
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2682168A1 (de) 2012-07-02 2014-01-08 Millipore Corporation Reinigung biologischer Moleküle
EP2889617B1 (de) 2012-08-27 2017-10-11 Asahi Kasei Medical Co., Ltd. Antikörperreinigungsverfahren mittels temperaturempfindlicher chromatographie
RS57013B1 (sr) 2012-09-11 2018-05-31 Coherus Biosciences Inc Korektno savijeni etanercept sa visokom čistoćom i odličnim prinosom
IN2015DN02055A (de) 2012-09-17 2015-08-14 Grace W R & Co
WO2014099577A1 (en) * 2012-12-17 2014-06-26 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
RU2658909C2 (ru) 2013-02-14 2018-06-26 НАНОПАРЕЙЛ, ЭлЭлСи Гибридные войлоки из нановолокон, полученных электропрядением
ES2665645T3 (es) * 2013-05-06 2018-04-26 Sanofi Proceso multietapa continuo para purificar anticuerpos
CN105848746B (zh) * 2013-09-05 2019-07-09 豪夫迈·罗氏有限公司 用于层析重复利用的方法
JPWO2015041218A1 (ja) * 2013-09-17 2017-03-02 株式会社カネカ 新規抗体精製方法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎＭｅｔｈｏｄａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎｍｅｔｈｏｄｕｓｉｎｇＣａｔｉｏｎＥｘｃｈａｎｇｅｒａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）
EP3698870A1 (de) 2013-12-12 2020-08-26 EMD Millipore Corporation Trennung von proteinen unter verwendung eines acrylamidhaltigen filters
EP3105580B1 (de) 2014-02-14 2023-10-04 Cytiva Sweden AB Mehrstufiges automatisches reinigungssystem
JP6293907B2 (ja) 2014-03-10 2018-03-14 リヒター ゲデオン エヌワイアールティー． プレクリーニング工程を用いた免疫グロブリンの精製
CN104826617B (zh) * 2014-03-25 2017-06-13 西北大学 一种用于蛋白质分离的wax/hic双功能混合模式色谱固定相及其制备方法
ES2929099T3 (es) 2014-05-02 2022-11-24 Grace W R & Co Material de soporte funcionalizado y métodos de fabricación y uso de material de soporte funcionalizado
EP3145951A1 (de) * 2014-06-24 2017-03-29 InSight Biopharmaceuticals Ltd. Verfahren zur reinigung von antikörpern
DE102014010353B4 (de) 2014-07-10 2024-09-12 Sartorius Stedim Biotech Gmbh Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien
CA2966515C (en) 2014-12-08 2021-04-27 Emd Millipore Corporation Mixed bed ion exchange adsorber
ES2896897T3 (es) 2015-06-05 2022-02-28 Grace W R & Co Agentes de clarificación para el bioprocesamiento de adsorbentes y métodos para producir y usar los mismos
WO2017176735A1 (en) * 2016-04-05 2017-10-12 Haemonetics Corporation Methods and devices for the enrichment of immunoglobulin from blood
CN107964044B (zh) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 从乳样中纯化抗cd20单克隆抗体的方法
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
EP3546475A1 (de) 2018-03-27 2019-10-02 Sanofi Volldurchflussverfahren zur reinigung rekombinanter proteine
WO2020125757A1 (en) * 2018-12-21 2020-06-25 Wuxi Biologics (Shanghai) Co., Ltd. A method for improving aggregate removal by protein a chromatography
FR3099066B1 (fr) 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
TW202128264A (zh) * 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
CN114555622A (zh) * 2019-10-04 2022-05-27 默克专利股份有限公司 蛋白质的纯化和病毒灭活
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法
CN113845562A (zh) * 2020-06-28 2021-12-28 佛山汉腾生物科技有限公司 目的蛋白纯化方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4490937A (en) * 1981-12-07 1985-01-01 Amcor Ltd. Insect electrocution device
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5256694A (en) * 1984-09-22 1993-10-26 Basf Aktiengesellschaft Diarylacetylenes, their preparation and their use
US5091178A (en) * 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US6054051A (en) * 1996-01-17 2000-04-25 Genentech, Inc. Tangential-flow filtration system
AU2003265235A1 (en) * 2002-04-26 2003-12-19 Genetech, Inc. Non-affinity purification of proteins
EP2261230B1 (de) * 2002-09-11 2017-05-10 Chugai Seiyaku Kabushiki Kaisha Verfahren zur Proteinreinigung
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
EP1685161A1 (de) * 2004-08-30 2006-08-02 Lonza Biologics plc Affinity- plus ionenaustauschchromatographie zur aufreinigung von antikörpern
WO2009017491A1 (en) * 2006-06-14 2009-02-05 Smithkline Beecham Corporation Methods for purifying antibodies using ceramic hydroxyapatite
FI2061803T4 (fi) * 2006-08-28 2023-03-14 Process for the purification of fc-containing proteins
AU2007291282B2 (en) * 2006-08-28 2011-10-20 Ares Trading S.A. Process for the purification of Fc-fusion proteins
JP2010516651A (ja) * 2007-01-17 2010-05-20 メルク セローノ ソシエテ アノニム Ｆｃ含有タンパク質の精製のための方法
US9433922B2 (en) * 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
US20090149638A1 (en) * 2007-10-03 2009-06-11 Ley Arthur C Systems and methods for purifying proteins
US20110105725A1 (en) * 2008-05-15 2011-05-05 Novo Nordisk A/S Antibody purification process
TW201028433A (en) * 2008-10-20 2010-08-01 Abbott Lab Viral inactivation during purification of antibodies

Also Published As

Publication number Publication date
JP2013501721A (ja) 2013-01-17
JP2015157846A (ja) 2015-09-03
JP6335838B2 (ja) 2018-05-30
EP2462157A4 (de) 2012-12-26
SG177577A1 (en) 2012-03-29
ES2817802T3 (es) 2021-04-08
KR20120089432A (ko) 2012-08-10
EP2462157B1 (de) 2020-06-17
JP5791602B2 (ja) 2015-10-07
EP2462157A1 (de) 2012-06-13
US8536316B2 (en) 2013-09-17
CN107188960A (zh) 2017-09-22
CN102574911B (zh) 2017-06-06
WO2011017514A1 (en) 2011-02-10
US20110065901A1 (en) 2011-03-17
CN102574911A (zh) 2012-07-11
KR101415660B1 (ko) 2014-07-16

Similar Documents

Publication Publication Date Title
IN2012DN00338A (de)
IN2012DN00801A (de)
MX2009007632A (es) Precipitacion de polielectrolito y purificacion de proteinas.
TW200801262A (en) Method for purifying silicon
MX336715B (es) Purificacion de iduronato-2-sulfatasa.
BRPI0917993A2 (pt) composições de célula-tronco mesenquimal purificada e métodos de purificação de composições de célula-tronco mesenquimal purificda.
PL2291329T3 (pl) System oczyszczania cieczy, zwłaszcza oczyszczania wody balastowej
PT2459715T (pt) Método para purificar adamts13 e outras proteínas recombinantes e suas composições
MX2011008621A (es) Proceso para la purificacion de lipopeptidos.
EA201070987A1 (ru) Очищенные гибридные белки иммуноглобулина и способы их очищения
EA201270616A1 (ru) Ингибиторы вируса гепатита с
HK1206755A1 (en) Low acidic species compositions and methods for producing and using the same
WO2010151799A3 (en) Compounds for modulating rna binding proteins and uses therefor
WO2010151797A3 (en) Compounds for modulating rna binding proteins and uses therefor
MY188566A (en) Method to improve virus removal in protein purification
WO2011017132A3 (en) Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
UA108636C2 (xx) Пептид
WO2008085962A3 (en) Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants
MX2011000281A (es) Fibrinogeno recombinante.
MX2011008179A (es) Peptidos para vacuna.
TW200738622A (en) Process for purifying (meth)acrylates
UA103197C2 (uk) Застосування ніфуртимоксу для лікування хвороб, спричинених трихомонадами
NZ708503A (en) Purification of x-ray contrast agents
PL2286887T3 (pl) Usuwanie endotoksyn ze środków kontrastowych
EA201270403A1 (ru) Способ и система для очистки полипептидов