IN2012DN03825A - - Google Patents

Info

Publication number
IN2012DN03825A
IN2012DN03825A IN3825DEN2012A IN2012DN03825A IN 2012DN03825 A IN2012DN03825 A IN 2012DN03825A IN 3825DEN2012 A IN3825DEN2012 A IN 3825DEN2012A IN 2012DN03825 A IN2012DN03825 A IN 2012DN03825A
Authority
IN
India
Prior art keywords
beta
glucosidase variants
methods
glucosidase
variants
Prior art date
Application number
Other languages
English (en)
Inventor
Richard R Bott
Thijs Kaper
Bradley Kelemen
Frits Goedegerbuur
Ronaldus Wilhelmus Hommes
Slavko Kralj
Paulien Kruithof
Igor Nikolaev
Johan Van Lieshout
Sander Van Stight-Thans
Gudrun Vogtentanz
Mats Sandgren
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of IN2012DN03825A publication Critical patent/IN2012DN03825A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IN3825DEN2012 2009-11-20 2010-11-19 IN2012DN03825A (2)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26324009P 2009-11-20 2009-11-20
PCT/US2010/057531 WO2011063308A2 (en) 2009-11-20 2010-11-19 Beta-glucosidase i variants with improved properties

Publications (1)

Publication Number Publication Date
IN2012DN03825A true IN2012DN03825A (2) 2015-08-28

Family

ID=43608030

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3825DEN2012 IN2012DN03825A (2) 2009-11-20 2010-11-19

Country Status (10)

Country Link
US (2) US9447400B2 (2)
EP (6) EP2599863B1 (2)
JP (2) JP2013511280A (2)
CN (2) CN102844429B (2)
BR (1) BR112012011711A2 (2)
CA (1) CA2780767A1 (2)
DK (6) DK2501806T3 (2)
IN (1) IN2012DN03825A (2)
RU (1) RU2012125624A (2)
WO (1) WO2011063308A2 (2)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2480660T5 (da) 2009-09-23 2020-11-09 Danisco Us Inc Hidtil ukendte glycosylhydrolaseenzymer og anvendelser heraf
RU2012126131A (ru) 2009-11-25 2013-12-27 Кодексис, Инк. РЕКОМБИНАНТНЫЕ ВАРИАНТЫ β-ГЛЮКОЗИДАЗЫ ДЛЯ ПРОДУКЦИИ РАСТВОРИМЫХ САХАРОВ ИЗ ЦЕЛЛЮЛОЗНОЙ БИОМАССЫ
AU2010333801B2 (en) 2009-12-23 2015-12-17 Danisco Us Inc. Methods for improving the efficiency of simultaneous saccharification and fermentation reactions
US10130697B2 (en) 2010-03-23 2018-11-20 Wisconsin Alumni Research Foundation (Warf) Vaccines comprising mutant attenuated influenza viruses
DK3023492T3 (en) 2010-10-01 2018-03-05 Novozymes Inc Beta-glucosidase variants and polynucleotides encoding them
KR20130132789A (ko) * 2010-11-05 2013-12-05 아사히 가라스 가부시키가이샤 스키조사카로미세스속 효모의 형질 전환체 및 그 제조 방법
JP6290626B2 (ja) 2011-03-17 2018-03-14 ダニスコ・ユーエス・インク 糖化プロセスにおける粘度を低下させる方法
CN102816748B (zh) * 2011-06-09 2014-07-16 中国科学院上海生命科学研究院 一种新型β-葡萄糖苷酶及其编码基因和应用
ES2655051T3 (es) 2011-08-26 2018-02-16 Wisconsin Alumni Research Foundation Virus de la gripe con segmento génico PB2 mutante como vacunas vivas atenuadas
WO2014088940A1 (en) 2012-12-07 2014-06-12 Danisco Us Inc. Compositions and methods of use
ES2521940B1 (es) 2013-05-10 2015-09-09 Abengoa Bioenergía Nuevas Tecnologías, S.A. Variantes de beta-glucosidasa con actividad de transglicosilación reducida
MX2016001317A (es) 2013-07-29 2016-04-07 Danisco Us Inc Variantes de enzimas.
CN105745322A (zh) * 2013-09-17 2016-07-06 易登尼有限公司 用于增加生物质糖化的改良的β-葡萄糖苷酶
RU2739004C1 (ru) * 2014-02-26 2020-12-21 Кхр. Хансен А/С Варианты химозина с улучшенными молокосвертывающими свойствами
WO2015196150A2 (en) 2014-06-20 2015-12-23 Wisconsin Alumni Research Foundation (Warf) Mutations that confer genetic stability to additional genes in influenza viruses
JP2017524363A (ja) * 2014-08-08 2017-08-31 ザイレコ，インコーポレイテッド アグリコシル化された酵素およびその使用
WO2016100837A1 (en) 2014-12-18 2016-06-23 Danisco Us Inc Engineered multifunctional enzymes and methods of use
US20180002683A1 (en) 2014-12-18 2018-01-04 Danisco Us Inc. Engineered multifunctional enzymes and methods of use
US10612058B2 (en) * 2014-12-19 2020-04-07 Danisco Us Inc Methods for saccharifying a starch substrate
US20180148683A1 (en) 2015-07-07 2018-05-31 Danisco Us Inc. Induction of gene expression using a high concentration sugar mixture
CN108368529A (zh) * 2015-12-10 2018-08-03 帝斯曼知识产权资产管理有限公司 β-葡糖苷酶及其用途
CN108368530A (zh) * 2015-12-10 2018-08-03 帝斯曼知识产权资产管理有限公司 β-葡糖苷酶及其用途
US20190002860A1 (en) * 2015-12-10 2019-01-03 Dsm Ip Assets B.V. Beta-glucosidase and uses thereof
CA3014435C (en) 2016-02-19 2023-04-18 Wisconsin Alumni Research Foundation (Warf) Improved influenza b virus replication for vaccine development
EP3336180A1 (en) * 2016-07-04 2018-06-20 Evonik Degussa GmbH Mutant alkb gene
WO2018053058A1 (en) 2016-09-14 2018-03-22 Danisco Us Inc. Lignocellulosic biomass fermentation-based processes
EP3523415A1 (en) 2016-10-04 2019-08-14 Danisco US Inc. Protein production in filamentous fungal cells in the absence of inducing substrates
WO2018106656A1 (en) 2016-12-06 2018-06-14 Danisco Us Inc Truncated lpmo enzymes and use thereof
MX2019007335A (es) 2016-12-21 2019-09-09 Dupont Nutrition Biosci Aps Métodos para usar serina proteasas termoestables.
WO2018164876A1 (en) 2017-03-06 2018-09-13 Dupont Nutrition Biosciences Aps Novel fungal fucosidases and their use in preventing and/or treating a pathogenic infection in an animal
BR112019023923A2 (pt) * 2017-05-16 2020-08-18 The Curators Of The University Of Missouri complexo de enzima imobilizada, aparelho biorreator, métodos para conversão enzimática de um substrato a um produto desejado, para produzir um complexo de enzima imobilizada e para usar um biorreator, biorreator, sistema de biorreator multienzimático de fluxo contínuo, sistema de biorreator, aparelhos de conversão de grupo sanguíneo de fluxo contínuo e de reator de múltiplas enzimas de distribuição de fármaco, e, sistema para cicatrização de ferida
WO2019074828A1 (en) 2017-10-09 2019-04-18 Danisco Us Inc CELLOBIOSE DEHYDROGENASE VARIANTS AND METHODS OF USE
JP7051491B2 (ja) * 2018-02-26 2022-04-11 花王株式会社 変異β－グルコシダーゼ
BR112020018294A2 (pt) 2018-03-09 2020-12-29 Danisco Us Inc. Glucoamilases e métodos de uso dos mesmos
WO2020010101A2 (en) 2018-07-04 2020-01-09 Danisco Us Inc Glucoamylases and methods of use, thereof
US12343390B2 (en) 2018-08-07 2025-07-01 Wisconsin Alumni Research Foundation (Warf) Recombinant biologically contained filovirus vaccine
JP7655849B2 (ja) 2018-08-20 2025-04-02 ウィスコンシン アルムニ リサーチ ファンデイション ヘマグルチニン（ｈａ）タンパク質内の非ドミナントエピトープに対する免疫応答を誘起するためのベクター
EP3877519B1 (en) 2018-11-09 2026-03-11 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
US12365886B2 (en) 2018-11-20 2025-07-22 International N&H Denmark Aps Engineered robust high Tm-phytase clade polypeptides and fragments thereof
US11241492B2 (en) * 2019-01-23 2022-02-08 Wisconsin Alumni Research Foundation (Warf) Mutations that confer genetic stability to genes in influenza viruses
WO2020163804A1 (en) 2019-02-08 2020-08-13 Wisconsin Alumni Research Foundation (Warf) Humanized cell line
US11390649B2 (en) 2019-05-01 2022-07-19 Wisconsin Alumni Research Foundation (Warf) Influenza virus replication for vaccine development
US11807872B2 (en) 2019-08-27 2023-11-07 Wisconsin Alumni Research Foundation (Warf) Recombinant influenza viruses with stabilized HA for replication in eggs
WO2021150874A1 (en) 2020-01-24 2021-07-29 Wisconsin Alumni Research Foundation (Warf) Recombinant influenza viruses with stabilized na
WO2021173974A1 (en) 2020-02-28 2021-09-02 Dupont Nutrition Biosciences Aps Feed compositions
US12290562B2 (en) 2020-03-25 2025-05-06 Wisconsin Alumni Research Foundation (Warf) Recombinant multivalent influenza viruses
CN115478060B (zh) * 2021-06-16 2023-11-28 弈柯莱生物科技(集团)股份有限公司 一种糖基转移酶及其应用
CN113842454B (zh) * 2021-09-30 2026-01-30 中国人民解放军空军军医大学 一种基于vsv载体的htnv疫苗及其制备方法和应用
CN119487187A (zh) 2021-10-15 2025-02-18 丹尼斯科美国公司 葡糖淀粉酶变体及其使用方法
MX2024005861A (es) 2021-11-17 2024-08-06 Int N&H Denmark Aps Modificación enzimática mejorada de galactolípidos en los alimentos.
CN116426506B (zh) * 2023-03-10 2024-01-30 云南师范大学 低温活性提高的β-木糖苷酶突变体D259G及其应用
CN118006590B (zh) * 2024-02-23 2024-12-27 南京师范大学常州合成生物学产业研究院有限公司 一种Microbacterium dextranolyticumβ-葡萄糖苷酶的突变体及方法和应用
CN118956830B (zh) * 2024-09-27 2025-09-09 安徽大学 一种β-葡萄糖苷酶突变体及其在水解丙二酰染料木苷中的应用
CN118853624B (zh) * 2024-09-29 2025-04-25 青岛奔月生物技术有限公司 催化莱鲍迪苷d生产莱鲍迪苷m的葡萄糖基转移酶突变体及其应用

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822516A (en) 1986-12-08 1989-04-18 Kao Corporation Detergent composition for clothing incorporating a cellulase
WO1989009259A1 (en) 1988-03-24 1989-10-05 Novo-Nordisk A/S A cellulase preparation
US5776757A (en) 1988-03-24 1998-07-07 Novo Nordisk A/S Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof
DK494089D0 (2) 1989-10-06 1989-10-06 Novo Nordisk As
US5326477A (en) 1990-05-07 1994-07-05 Bio-Sep, Inc. Process for digesting solid waste
US5246853A (en) 1990-10-05 1993-09-21 Genencor International, Inc. Method for treating cotton-containing fabric with a cellulase composition containing endoglucanase components and which composition is free of exo-cellobiohydrolase I
US5475101A (en) 1990-10-05 1995-12-12 Genencor International, Inc. DNA sequence encoding endoglucanase III cellulase
DK0553280T4 (da) 1990-10-05 2010-11-15 Genencor Int Fremgangsmåde til behandling af bomuldsholdige tekstiler med cellulase
US5997913A (en) * 1990-12-10 1999-12-07 Genencor International, Inc. Method enhancing flavor and aroma in foods by overexpression of β-glucosidase
WO1992010581A1 (en) 1990-12-10 1992-06-25 Genencor International, Inc. IMPROVED SACCHARIFICATION OF CELLULOSE BY CLONING AND AMPLIFICATION OF THE β-GLUCOSIDASE GENE OF TRICHODERMA REESEI
US6021536A (en) 1993-03-04 2000-02-08 Wasinger; Eric Mechanical desizing and abrading device
FI932521A0 (fi) 1993-06-02 1993-06-02 Alko Ab Oy Nytt endoglukanasenzym
US6426200B1 (en) 1994-09-15 2002-07-30 University Of Georgia Research Foundation, Inc. Methods for enzymatic deinking of waste paper
EP0805856B2 (en) 1995-01-26 2009-04-01 Novozymes A/S Animal feed additives comprising xylanase
AU6513096A (en) 1995-07-19 1997-02-18 Novo Nordisk A/S Treatment of fabrics
DE69631610T2 (de) 1995-11-15 2004-09-16 Novozymes A/S Verfahren zum gleichzeitigen Entschlichten und "Stone-Washing" von gefärbtem Denim
EP0877799A1 (en) 1996-01-29 1998-11-18 Novo Nordisk A/S Process for desizing cellulosic fabric
US6254722B1 (en) 1996-03-27 2001-07-03 North Carolina State University Method for making dissolving pulp from paper products containing hardwood fibers
US7883872B2 (en) 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
US6069122A (en) 1997-06-16 2000-05-30 The Procter & Gamble Company Dishwashing detergent compositions containing organic diamines for improved grease cleaning, sudsing, low temperature stability and dissolution
US6265204B1 (en) 1997-01-17 2001-07-24 Genencor International, Inc. DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi
US6255115B1 (en) 1997-04-07 2001-07-03 Unilever Patent Holdings Bv Agrobacterium mediated transformation of moulds, in particular those belonging to the genus Aspergillus
AU7768798A (en) 1997-06-10 1998-12-30 Xyrofin Oy Process for the production of sylose from a paper-grade, hardwood pulp
EP1032644B1 (en) 1997-11-10 2003-03-19 The Procter & Gamble Company Process for preparing a detergent tablet
US6187580B1 (en) 1997-11-24 2001-02-13 Novo Nordisk A/S Pectate lyases
AU3408199A (en) 1998-05-01 1999-11-23 Novo Nordisk A/S Enhancers such as n-hydroxyacetanilide
DE19824705A1 (de) 1998-06-03 1999-12-09 Henkel Kgaa Amylase und Protease enthaltende Wasch- und Reinigungsmittel
US5980581A (en) 1998-09-08 1999-11-09 The Virkler Company Process for desizing and cleaning woven fabrics and garments
US6024766A (en) 1999-01-27 2000-02-15 Wasinger; Eric M. Process for enzymatic desizing of garments and enzyme deactivation
US6982159B2 (en) 2001-09-21 2006-01-03 Genencor International, Inc. Trichoderma β-glucosidase
US7045332B2 (en) 2001-12-18 2006-05-16 Genencor International, Inc. BGL4 β-glucosidase and nucleic acids encoding the same
US7005289B2 (en) 2001-12-18 2006-02-28 Genencor International, Inc. BGL5 β-glucosidase and nucleic acids encoding the same
DK1622921T3 (da) * 2003-05-02 2010-09-13 Novozymes Inc Varianter af beta-glucosidaser
US20060041961A1 (en) 2004-03-25 2006-02-23 Abad Mark S Genes and uses for pant improvement
US7413887B2 (en) 2004-05-27 2008-08-19 Genecor International, Inc. Trichoderma reesei glucoamylase and homologs thereof
EP1869194A2 (en) 2005-04-12 2007-12-26 E.I.Du pont de nemours and company Treatment of biomass to obtain a target chemical
US8097772B2 (en) * 2005-08-04 2012-01-17 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
US7923236B2 (en) * 2007-08-02 2011-04-12 Dyadic International (Usa), Inc. Fungal enzymes
CN101796195A (zh) 2007-09-07 2010-08-04 丹尼斯科美国公司 β-葡糖苷酶增强的丝状真菌全纤维素酶组合物和使用方法
CA3069361C (en) 2007-10-09 2023-11-28 Danisco Us Inc. Glucoamylase variants with altered properties
US10676751B2 (en) 2008-02-29 2020-06-09 The Trustees Of The University Of Pennsylvania Production and use of plant degrading materials
BRPI0918823A2 (pt) * 2008-08-29 2019-09-24 Iogen Energy Corp beta-glicosidases modificadas com estabilidades aperfeicoada
FR2935986B1 (fr) 2008-09-12 2012-11-23 Inst Francais Du Petrole Variants de beta-glucosidase a activite amelioree et leurs utilisations.
US8486683B2 (en) * 2009-05-29 2013-07-16 Iogen Energy Corporation Beta-glucosidase enzymes
RU2013146240A (ru) 2011-03-17 2015-04-27 ДАНИСКО ЮЭс ИНК. Ферменты гликозил-гидролазы и их применение для гидролиза биомассы
JP6290626B2 (ja) 2011-03-17 2018-03-14 ダニスコ・ユーエス・インク 糖化プロセスにおける粘度を低下させる方法
US8468683B2 (en) * 2011-10-31 2013-06-25 HGST Netherlands B.V. High bevel angle magnetic writer pole fabrication process
CA2888753A1 (en) 2012-10-31 2014-05-08 Danisco Us Inc. Beta-glucosidase from magnaporthe grisea
US20150252344A1 (en) 2012-10-31 2015-09-10 Danisco Us Inc. Beta-glucosidase from neurospora crassa
EP2914719A1 (en) 2012-10-31 2015-09-09 Danisco US Inc. Compositions and methods of use

Also Published As

Publication number Publication date
EP2599861A3 (en) 2013-10-09
EP2599864A2 (en) 2013-06-05
DK2599863T3 (da) 2017-11-06
EP2602317A2 (en) 2013-06-12
EP2602317B1 (en) 2017-08-02
EP2599864B1 (en) 2017-08-02
CN105316303A (zh) 2016-02-10
EP2501806B1 (en) 2017-08-02
DK2501806T3 (da) 2017-11-06
EP2599862A2 (en) 2013-06-05
EP2599864A3 (en) 2013-10-09
CN102844429B (zh) 2015-11-25
EP2599862A3 (en) 2013-10-09
EP2599863A2 (en) 2013-06-05
CN102844429A (zh) 2012-12-26
JP2015211678A (ja) 2015-11-26
EP2599862B1 (en) 2017-08-02
EP2599861B1 (en) 2017-08-02
DK2599862T3 (da) 2017-11-06
CA2780767A1 (en) 2011-05-26
DK2602317T3 (da) 2017-11-13
EP2501806A2 (en) 2012-09-26
CN105316303B (zh) 2019-05-31
US20170145396A1 (en) 2017-05-25
BR112012011711A2 (pt) 2021-11-03
EP2599861A2 (en) 2013-06-05
WO2011063308A8 (en) 2012-06-14
EP2602317A3 (en) 2013-10-23
US20130143301A1 (en) 2013-06-06
DK2599864T3 (da) 2017-11-06
DK2599861T3 (da) 2017-11-06
RU2012125624A (ru) 2013-12-27
WO2011063308A2 (en) 2011-05-26
WO2011063308A3 (en) 2011-08-11
JP2013511280A (ja) 2013-04-04
US9447400B2 (en) 2016-09-20
EP2599863A3 (en) 2013-10-09
EP2599863B1 (en) 2017-08-02

Similar Documents

Publication Publication Date Title
IN2012DN03825A (2)
MX2016001315A (es) Variantes de enzimas.
MX2012007710A (es) Alfa-amilasas.
PH12013501799A1 (en) Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials
MX339581B (es) Variantes de subtilasa.
MY158663A (en) Fermentation broth formulations
MX344970B (es) Medio de cultivo celular para la expresion de la proteina adamts.
EP3805348A3 (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2011061032A3 (de) Zellen, nukleinsäuren, enzyme und deren verwendung sowie verfahren zur herstellung von sophorolipiden
AP2011005777A0 (en) Methods and compositions related to thioesterase enzymes.
WO2011053940A3 (en) Templated nanoconjugates
MX2013003681A (es) Ácidos nucleicos manipulados y métodos de uso de los mismos.
IN2014CN02100A (2)
MX2012003473A (es) Polipeptidos que tienen actividad celulitica mejorada y polinucleotidos que codifican para los mismos.
ATE533838T1 (de) Verfahren zur verbesserten einführung von dna in bakterienzellen
EA201270151A1 (ru) Способы и композиции для рекомбинантного биосинтеза h-алканов
CO6470854A2 (es) Variantes de celulasa con expresión, actividad y/o estabilidad mejoradas, y uso de las mismas
WO2011159684A3 (en) Generation of induced pluripotent stem cells from small volumes of peripheral blood
EP3892709A3 (en) Variants and compositions comprising variants with high stability in presence of a chelating agent
MX2009004739A (es) Efectos biologicos mejorados de composiciones que comprenden acido rosmarinico.
MX2010000348A (es) Cultivo de celulas madre pluripotentes individuales.
IN2012DN02814A (2)
MY182946A (en) Production of organic acids by fermentation at low ph
MX349801B (es) Sustratos de enzimas de ácido nucleico.
MX2012001060A (es) Carbohidrato-oxidasas.