IN2014MN02156A - - Google Patents

Info

Publication number
IN2014MN02156A
IN2014MN02156A IN2156MUN2014A IN2014MN02156A IN 2014MN02156 A IN2014MN02156 A IN 2014MN02156A IN 2156MUN2014 A IN2156MUN2014 A IN 2156MUN2014A IN 2014MN02156 A IN2014MN02156 A IN 2014MN02156A
Authority
IN
India
Prior art keywords
acid
microparticles
alfentanil
presented
pain
Prior art date
Application number
Other languages
English (en)
Inventor
Anders Pettersson
Emil Schwan
Barbro Johansson
Original Assignee
Orexo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48577134&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014MN02156(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB1207701.2A external-priority patent/GB201207701D0/en
Priority claimed from GBGB1221130.6A external-priority patent/GB201221130D0/en
Application filed by Orexo Ab filed Critical Orexo Ab
Publication of IN2014MN02156A publication Critical patent/IN2014MN02156A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN2156MUN2014 2012-05-02 2013-05-01 IN2014MN02156A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1207701.2A GB201207701D0 (en) 2012-05-02 2012-05-02 New pharmaceutical composition
GBGB1221130.6A GB201221130D0 (en) 2012-11-23 2012-11-23 New pharmaceutical composition
PCT/GB2013/051131 WO2013164620A1 (fr) 2012-05-02 2013-05-01 Nouvelle composition d'alfentanil pour le traitement d'une douleur aiguë

Publications (1)

Publication Number Publication Date
IN2014MN02156A true IN2014MN02156A (fr) 2015-08-28

Family

ID=48577134

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2156MUN2014 IN2014MN02156A (fr) 2012-05-02 2013-05-01

Country Status (33)

Country Link
US (4) US8815911B2 (fr)
EP (2) EP2849730B1 (fr)
JP (1) JP6275696B2 (fr)
KR (1) KR20150005695A (fr)
CN (1) CN104427978B (fr)
AU (1) AU2013255640B2 (fr)
BR (1) BR112014027213A8 (fr)
CA (1) CA2871805A1 (fr)
CL (1) CL2014002979A1 (fr)
CO (1) CO7170181A2 (fr)
CY (2) CY1118570T1 (fr)
DK (2) DK2849730T3 (fr)
EA (1) EA028110B1 (fr)
ES (2) ES2614757T3 (fr)
HR (2) HRP20161634T1 (fr)
HU (1) HUE031792T2 (fr)
IL (1) IL235272B (fr)
IN (1) IN2014MN02156A (fr)
LT (2) LT2849730T (fr)
ME (1) ME02644B (fr)
MX (1) MX360665B (fr)
NZ (1) NZ701428A (fr)
PE (1) PE20142444A1 (fr)
PH (1) PH12014502407A1 (fr)
PL (2) PL3150199T3 (fr)
PT (2) PT3150199T (fr)
RS (2) RS55489B1 (fr)
SG (1) SG11201407081PA (fr)
SI (2) SI3150199T1 (fr)
SM (3) SMT201800585T1 (fr)
TR (1) TR201815935T4 (fr)
WO (1) WO2013164620A1 (fr)
ZA (1) ZA201407559B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12014500316B1 (en) 2011-09-19 2018-10-03 Orexo Ab New abuse-resistant pharmaceutical composition for the treatment of opioid dependence
TR201815935T4 (tr) * 2012-05-02 2018-11-21 Orexo Ab Akut ağrının tedavisi için yeni alfentanil bileşimi.
WO2017180659A1 (fr) * 2016-04-11 2017-10-19 Arizona Board Of Regents On Behalf Of University Of Arizona Modulateurs des récepteurs opioïdes
JP7023054B2 (ja) * 2017-04-05 2022-02-21 東和薬品株式会社 レベチラセタム含有医薬組成物及びその製造方法
CN115047109B (zh) * 2022-06-17 2024-05-31 三明海关综合技术服务中心 一种检测食品中芬太尼类新精神活性物质的方法

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US5785989A (en) * 1985-05-01 1998-07-28 University Utah Research Foundation Compositions and methods of manufacturing of oral dissolvable medicaments
DE19749724A1 (de) 1997-11-11 1999-06-10 Gruenenthal Gmbh Verwendung einer Kombination aus Opioid und alpha-adrenergem Agonisten in Schmerzmitteln
SE9803240D0 (sv) 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
SE9803239D0 (sv) 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
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JP4850346B2 (ja) * 2001-03-15 2012-01-11 救急薬品工業株式会社 粘膜貼付剤
US20030068356A1 (en) 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
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CA2512559A1 (fr) 2003-01-31 2004-08-12 Orexo Ab Composition pharmaceutique a effet rapide
KR101170844B1 (ko) 2003-02-24 2012-08-02 파마슈티칼 프로덕션스, 인크. 경점막 약물 전달 시스템
US20050042281A1 (en) 2003-08-21 2005-02-24 Singh Nikhilesh N. Compositions for delivering therapeutic agents across the oral mucosa
US7858121B2 (en) * 2003-12-31 2010-12-28 Cima Labs, Inc. Effervescent oral fentanyl dosage form and methods of administering fentanyl
EP1708686B1 (fr) 2003-12-31 2011-02-16 Cima Labs Inc. Forme galenique de fentanyl generalement lineaire effervescente et orale et ses procedes d'administration
DE602004031771D1 (de) 2003-12-31 2011-04-21 Cima Labs Inc Brauseformen von opiaten zur oralen anwendung und verfahren zur verabreichung von oxycodon
US20070036853A1 (en) 2003-12-31 2007-02-15 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
FR2883179B1 (fr) 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
EP1863456A1 (fr) 2005-03-28 2007-12-12 Orexo AB Nouvelles compositions pharmaceutiques utiles dans le traitement de la douleur
US20060281775A1 (en) * 2005-06-14 2006-12-14 Applied Pharmacy Services, Inc. Two-component pharmaceutical composition for the treatment of pain
US20070104763A1 (en) * 2005-11-10 2007-05-10 Navinta Llc Composition of fentanyl citrate oral solid transmucosal dosage form, excipient and binding material therefore, and methods of making
US8252328B2 (en) 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8535714B2 (en) * 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
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TR201815935T4 (tr) * 2012-05-02 2018-11-21 Orexo Ab Akut ağrının tedavisi için yeni alfentanil bileşimi.

Also Published As

Publication number Publication date
MX2014013176A (es) 2015-01-19
SI3150199T1 (sl) 2018-12-31
US20140005223A1 (en) 2014-01-02
BR112014027213A8 (pt) 2018-01-16
KR20150005695A (ko) 2015-01-14
SG11201407081PA (en) 2014-11-27
CN104427978A (zh) 2015-03-18
US20180214437A1 (en) 2018-08-02
JP2015515974A (ja) 2015-06-04
CL2014002979A1 (es) 2014-12-05
HRP20181761T1 (hr) 2018-12-28
US9782396B2 (en) 2017-10-10
AU2013255640A1 (en) 2014-11-20
SMT201700086T1 (it) 2017-03-08
US9345698B2 (en) 2016-05-24
JP6275696B2 (ja) 2018-02-14
EP3150199A1 (fr) 2017-04-05
SMT201800585T1 (it) 2019-01-11
ZA201407559B (en) 2016-05-25
CY1120820T1 (el) 2019-12-11
HK1203399A1 (en) 2015-10-30
US20170071927A1 (en) 2017-03-16
DK3150199T3 (en) 2018-11-12
IL235272B (en) 2018-10-31
EP3150199B1 (fr) 2018-08-08
RS57951B1 (sr) 2019-01-31
ME02644B (fr) 2017-06-20
PH12014502407B1 (en) 2015-01-12
NZ701428A (en) 2016-10-28
PT2849730T (pt) 2017-02-15
SI2849730T1 (sl) 2017-02-28
HUE031792T2 (en) 2017-07-28
US8815911B2 (en) 2014-08-26
PE20142444A1 (es) 2015-01-09
CY1118570T1 (el) 2017-07-12
ES2614757T3 (es) 2017-06-01
ES2694644T3 (es) 2018-12-26
EP2849730A1 (fr) 2015-03-25
CN104427978B (zh) 2017-03-01
US20150133501A1 (en) 2015-05-14
HRP20161634T1 (hr) 2017-01-13
DK2849730T3 (en) 2017-02-13
PL3150199T3 (pl) 2019-03-29
MX360665B (es) 2018-11-13
PT3150199T (pt) 2018-11-21
CA2871805A1 (fr) 2013-11-07
CO7170181A2 (es) 2015-01-28
PH12014502407A1 (en) 2015-01-12
EA201401200A1 (ru) 2015-02-27
PL2849730T3 (pl) 2017-05-31
AU2013255640B2 (en) 2017-06-15
TR201815935T4 (tr) 2018-11-21
EA028110B1 (ru) 2017-10-31
WO2013164620A1 (fr) 2013-11-07
EP2849730B1 (fr) 2016-11-09
LT2849730T (lt) 2016-12-27
SMT201700086B (it) 2017-03-08
LT3150199T (lt) 2018-11-12
BR112014027213A2 (pt) 2017-06-27
RS55489B1 (sr) 2017-04-28

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