IS1999B - 4-Arýl-1-fenýlalkýl-1.2.3.6-tetrahýdrópýridín semhafa tauganærandi og taugaverjandi virkni - Google Patents

4-Arýl-1-fenýlalkýl-1.2.3.6-tetrahýdrópýridín semhafa tauganærandi og taugaverjandi virkni

Info

Publication number: IS1999B
Authority: IS; Iceland
Prior art keywords: alkyl; tetrahydropyridine; aryl; phenylalkyl; neuromuscular
Prior art date: 1995-06-28

Application number

IS4641A

Other languages

English (en)

Other versions

IS4641A (is

Inventor

Badone Domenico

Baroni Marco

Cardamone Rosanna

Fournier Jacqueline

Guzzi Umberto

Ielmini Alessandra

Original Assignee

Sanofi-Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-28

Filing date

1997-12-23

Publication date

2005-04-15

1997-12-23 Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis

1997-12-23 Publication of IS4641A publication Critical patent/IS4641A/is

2005-04-15 Publication of IS1999B publication Critical patent/IS1999B/is

Links

230000000694 effects Effects 0.000 title 1
230000002232 neuromuscular Effects 0.000 title 1
239000002858 neurotransmitter agent Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
-1 phenoxy, phenylamino Chemical group 0.000 abstract 3
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 abstract 1
150000003863 ammonium salts Chemical class 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000005111 carboxyalkoxy group Chemical group 0.000 abstract 1
125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
125000006310 cycloalkyl amino group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 1
125000000596 cyclohexenyl group Chemical group C1(=CCCCC1)* 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000000286 phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
125000005504 styryl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)

IS4641A 1995-06-28 1997-12-23 4-Arýl-1-fenýlalkýl-1.2.3.6-tetrahýdrópýridín semhafa tauganærandi og taugaverjandi virkni IS1999B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9507760A FR2736053B1 (fr)	1995-06-28	1995-06-28	Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
PCT/FR1996/000995 WO1997001536A1 (fr)	1995-06-28	1996-06-26	4-aryl-1-phenylalkyl-1,2,3,6-tetrahydropyridines ayant une activite neurotrophique et neuroprotectrice

Publications (2)

Publication Number	Publication Date
IS4641A IS4641A (is)	1997-12-23
IS1999B true IS1999B (is)	2005-04-15

Family

ID=9480466

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS4641A IS1999B (is)	1995-06-28	1997-12-23	4-Arýl-1-fenýlalkýl-1.2.3.6-tetrahýdrópýridín semhafa tauganærandi og taugaverjandi virkni

Country Status (29)

Country	Link
US (1)	US5981754A (is)
EP (2)	EP1216996A3 (is)
JP (2)	JP3147906B2 (is)
KR (1)	KR100460581B1 (is)
CN (1)	CN1153765C (is)
AT (1)	ATE223897T1 (is)
AU (1)	AU715090B2 (is)
BR (1)	BR9608662A (is)
CA (1)	CA2225746C (is)
CY (1)	CY2312B1 (is)
CZ (1)	CZ291075B6 (is)
DE (1)	DE69623631T2 (is)
DK (1)	DK0837848T3 (is)
EE (1)	EE03870B1 (is)
ES (1)	ES2183965T3 (is)
FR (1)	FR2736053B1 (is)
HU (1)	HUP9900055A3 (is)
IL (1)	IL122159A (is)
IS (1)	IS1999B (is)
NO (1)	NO310144B1 (is)
NZ (1)	NZ312723A (is)
PL (2)	PL192353B1 (is)
PT (1)	PT837848E (is)
RU (1)	RU2163237C2 (is)
SK (2)	SK283707B6 (is)
TR (1)	TR199701710T1 (is)
UA (1)	UA62914C2 (is)
WO (1)	WO1997001536A1 (is)
ZA (1)	ZA965527B (is)

Families Citing this family (36)

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FR2762514B1 (fr) *	1997-04-29	1999-10-22	Sanofi Sa	Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
FR2763847B1 (fr) *	1997-05-28	2003-06-06	Sanofi Sa	Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
FR2771006B1 (fr) *	1997-11-14	2000-12-01	Sanofi Sa	Association de principes actifs pour le traitement de la demence senile du type alzheimer
CO4980891A1 (es) *	1997-11-14	2000-11-27	Sanofi Sa	Asociacion de principios activos para el tratamiento de la demencia senil de tipo azheimer
FR2771007B1 (fr) *	1997-11-14	2000-12-01	Sanofi Sa	Association de principes actifs pour le traitement de la demence senile du type alzheimer
AU4685699A (en) *	1998-06-19	2000-01-05	Eli Lilly And Company	Preparation of heteroaryl compounds
FR2803593B1 (fr) *	2000-01-06	2002-02-15	Sanofi Synthelabo	Nouvelles tetrahydropyridines, procede pour leur preparation et compositions pharmaceutiques les contenant
US7186720B2 (en) *	2001-04-20	2007-03-06	Sanofi-Aventis	Tetrahydropyridyl-alkyl-heterocycles, method for preparing the same and pharmaceutical compositions containing the same
FR2823748B1 (fr) *	2001-04-20	2004-02-20	Sanofi Synthelabo	Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2840896B1 (fr) *	2002-06-18	2005-04-08	Sanofi Synthelabo	Phenyl-et pyridyl-piperazines, procede pour leur preparation et compositions pharmaceutiques les contenant
CN1726209B (zh) *	2002-12-16	2011-04-13	三菱制药株式会社	3-取代的-4-嘧啶酮衍生物
WO2005016910A1 (ja)	2003-08-18	2005-02-24	Sankio Chemical Co., Ltd.	ピリジルテトラヒドロピリジン類およびピリジルピペリジン類とそれらの製造方法
TWI350168B (en)	2004-05-07	2011-10-11	Incyte Corp	Amido compounds and their use as pharmaceuticals
WO2006002350A1 (en) *	2004-06-24	2006-01-05	Incyte Corporation	Amido compounds and their use as pharmaceuticals
US8071624B2 (en)	2004-06-24	2011-12-06	Incyte Corporation	N-substituted piperidines and their use as pharmaceuticals
CA2571258A1 (en) *	2004-06-24	2006-01-05	Incyte Corporation	Amido compounds and their use as pharmaceuticals
CA2584502A1 (en)	2004-06-24	2006-01-05	Incyte Corporation	2-methylpropanamides and their use as pharmaceuticals
US20050288317A1 (en) *	2004-06-24	2005-12-29	Wenqing Yao	Amido compounds and their use as pharmaceuticals
AU2005273986A1 (en) *	2004-08-10	2006-02-23	Incyte Corporation	Amido compounds and their use as pharmaceuticals
US8110581B2 (en) *	2004-11-10	2012-02-07	Incyte Corporation	Lactam compounds and their use as pharmaceuticals
ES2547724T3 (es) *	2004-11-10	2015-10-08	Incyte Corporation	Compuestos de lactama y su uso como productos farmacéuticos
CN101103016A (zh) *	2004-11-18	2008-01-09	因塞特公司	11-β羟基类固醇脱氢酶1型抑制剂及其使用方法
FR2883285B1 (fr) *	2005-03-17	2007-05-18	Sanofi Aventis Sa	Sel besylate de la 7-(2-(4-(3-trifluoromethyl-phenyl) -1,2,3,6-tetrahudro-pyrid-1-yl)ethyl) isoquinoleine, sa preparation et son utilisation en therapeutique
JP4864342B2 (ja) *	2005-04-27	2012-02-01	北興化学工業株式会社	ビアリール化合物の製造方法
CA2621255A1 (en) *	2005-09-21	2007-04-05	Incyte Corporation	Amido compounds and their use as pharmaceuticals
CA2630492C (en) *	2005-12-05	2015-04-14	Incyte Corporation	Spiro-lactam compounds
WO2007084314A2 (en) *	2006-01-12	2007-07-26	Incyte Corporation	MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
AU2007210018A1 (en) *	2006-01-31	2007-08-09	Incyte Corporation	Amido compounds and their use as pharmaceuticals
US20070213311A1 (en) *	2006-03-02	2007-09-13	Yun-Long Li	Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
WO2007103719A2 (en) *	2006-03-03	2007-09-13	Incyte Corporation	MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
JP2009535420A (ja) *	2006-05-01	2009-10-01	インサイト・コーポレイション	１１−βヒドロキシルステロイドデヒドロゲナーゼタイプ１のモジュレーターとしてのテトラ置換ウレア
EP2018378A2 (en) *	2006-05-17	2009-01-28	Incyte Corporation	Heterocyclic inhibitors of 11-b hydroxyl steroid dehydrogenase type i and methods of using the same
CL2008001839A1 (es) *	2007-06-21	2009-01-16	Incyte Holdings Corp	Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades.
WO2009086277A1 (en)	2007-12-20	2009-07-09	Envivo Pharmaceuticals, Inc.	Tetrasubstituted benzenes
CN102753513B (zh) *	2010-01-19	2015-03-18	拜耳知识产权有限责任公司	制备芳基和杂芳基乙酸衍生物的方法
US10858351B2 (en)	2017-04-26	2020-12-08	Alberta Research Chemicals Inc.	Substituted tetrahydropyridine derivatives as IDO-1 inhibitors and uses thereof

Family Cites Families (5)

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Publication number	Priority date	Publication date	Assignee	Title
EP0398578B1 (en) *	1989-05-17	1997-03-12	Pfizer Inc.	2-piperidino-1-alkanol derivatives as antiischemic agents
FR2650505B1 (fr) *	1989-08-07	1994-06-03	Midy Spa	Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2662355B1 (fr) *	1990-05-22	1994-11-10	Sanofi Sa	Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
HU211019B (en) *	1991-12-02	1995-09-28	Richter Gedeon Vegyeszet	Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
DE4325855A1 (de) *	1993-08-02	1995-02-09	Boehringer Ingelheim Kg	Neue Benzoesäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

1995
- 1995-06-28 FR FR9507760A patent/FR2736053B1/fr not_active Expired - Fee Related
1996
- 1996-06-26 BR BR9608662A patent/BR9608662A/pt not_active IP Right Cessation
- 1996-06-26 US US08/973,712 patent/US5981754A/en not_active Expired - Fee Related
- 1996-06-26 CZ CZ19974222A patent/CZ291075B6/cs not_active IP Right Cessation
- 1996-06-26 JP JP50420697A patent/JP3147906B2/ja not_active Expired - Fee Related
- 1996-06-26 DK DK96924023T patent/DK0837848T3/da active
- 1996-06-26 EP EP02006482A patent/EP1216996A3/fr not_active Withdrawn
- 1996-06-26 CN CNB961950900A patent/CN1153765C/zh not_active Expired - Fee Related
- 1996-06-26 PT PT96924023T patent/PT837848E/pt unknown
- 1996-06-26 DE DE69623631T patent/DE69623631T2/de not_active Expired - Fee Related
- 1996-06-26 EP EP96924023A patent/EP0837848B1/fr not_active Expired - Lifetime
- 1996-06-26 WO PCT/FR1996/000995 patent/WO1997001536A1/fr not_active Ceased
- 1996-06-26 SK SK1781-97A patent/SK283707B6/sk unknown
- 1996-06-26 IL IL12215996A patent/IL122159A/en not_active IP Right Cessation
- 1996-06-26 EE EE9700348A patent/EE03870B1/xx not_active IP Right Cessation
- 1996-06-26 UA UA97126360A patent/UA62914C2/uk unknown
- 1996-06-26 TR TR97/01710T patent/TR199701710T1/xx unknown
- 1996-06-26 HU HU9900055A patent/HUP9900055A3/hu unknown
- 1996-06-26 PL PL357052A patent/PL192353B1/pl not_active IP Right Cessation
- 1996-06-26 RU RU98101492/04A patent/RU2163237C2/ru not_active IP Right Cessation
- 1996-06-26 ES ES96924023T patent/ES2183965T3/es not_active Expired - Lifetime
- 1996-06-26 KR KR1019970709747A patent/KR100460581B1/ko not_active Expired - Fee Related
- 1996-06-26 AU AU64619/96A patent/AU715090B2/en not_active Ceased
- 1996-06-26 AT AT96924023T patent/ATE223897T1/de not_active IP Right Cessation
- 1996-06-26 SK SK593-2003A patent/SK285433B6/sk unknown
- 1996-06-26 CA CA002225746A patent/CA2225746C/en not_active Expired - Fee Related
- 1996-06-26 NZ NZ312723A patent/NZ312723A/en unknown
- 1996-06-26 PL PL96324216A patent/PL187087B1/pl not_active IP Right Cessation
- 1996-06-28 ZA ZA965527A patent/ZA965527B/xx unknown
1997
- 1997-12-23 IS IS4641A patent/IS1999B/is unknown
- 1997-12-23 NO NO19976079A patent/NO310144B1/no unknown
2000
- 2000-07-31 JP JP2000231069A patent/JP3302351B2/ja not_active Expired - Fee Related
2003
- 2003-01-15 CY CY0300004A patent/CY2312B1/xx unknown

Also Published As

Publication number	Publication date
FR2736053A1 (fr)	1997-01-03
JP3302351B2 (ja)	2002-07-15
BR9608662A (pt)	1999-05-04
ES2183965T3 (es)	2003-04-01
DK0837848T3 (da)	2003-01-06
JP2001114763A (ja)	2001-04-24
EE03870B1 (et)	2002-10-15
KR19990028431A (ko)	1999-04-15
DE69623631T2 (de)	2003-08-07
ATE223897T1 (de)	2002-09-15
SK283707B6 (sk)	2003-12-02
SK285433B6 (sk)	2007-01-04
CA2225746A1 (en)	1997-01-16
KR100460581B1 (ko)	2005-04-14
WO1997001536A1 (fr)	1997-01-16
EP1216996A2 (fr)	2002-06-26
HUP9900055A2 (hu)	1999-04-28
JPH11506118A (ja)	1999-06-02
SK178197A3 (en)	1998-07-08
IL122159A0 (en)	1998-04-05
PL187087B1 (pl)	2004-05-31
DE69623631D1 (en)	2002-10-17
FR2736053B1 (fr)	1997-09-19
JP3147906B2 (ja)	2001-03-19
RU2163237C2 (ru)	2001-02-20
PT837848E (pt)	2002-12-31
CZ291075B6 (cs)	2002-12-11
CN1153765C (zh)	2004-06-16
NO976079D0 (no)	1997-12-23
US5981754A (en)	1999-11-09
IL122159A (en)	2001-06-14
EP0837848A1 (fr)	1998-04-29
IS4641A (is)	1997-12-23
EE9700348A (et)	1998-06-15
TR199701710T1 (xx)	1998-05-21
CZ422297A3 (cs)	1998-04-15
HK1014952A1 (en)	1999-10-08
HUP9900055A3 (en)	1999-11-29
EP0837848B1 (fr)	2002-09-11
UA62914C2 (en)	2004-01-15
MX9710472A (es)	1998-03-31
EP1216996A3 (fr)	2003-10-15
CA2225746C (en)	2004-05-18
PL324216A1 (en)	1998-05-11
PL192353B1 (pl)	2006-10-31
CY2312B1 (en)	2003-11-14
NO976079L (no)	1997-12-23
ZA965527B (en)	1997-01-24
NZ312723A (en)	1999-10-28
CN1189154A (zh)	1998-07-29
AU6461996A (en)	1997-01-30
AU715090B2 (en)	2000-01-13
NO310144B1 (no)	2001-05-28

Publication	Publication Date	Title
IS4641A (is)	1997-12-23	4-Arýl-1-fenýlalkýl-1.2.3.6-tetrahýdrópýridín semhafa tauganærandi og taugaverjandi virkni
GR3029408T3 (en)	1999-05-28	Novel piperidine derivatives, useful as neurokinin receptor antagonists
IL115572A0 (en)	1996-01-19	Novel substituted 4-(azanaphthoylamino)-piperidines salts of these and pharmaceutical compositions containing them
NO914218D0 (no)	1991-10-28	Synergistiske ultrafiolettabsorberblandinger inneholdendehydroksyaryltriaziner og tetraalkylpiperidiner
AU3443595A (en)	1996-05-09	Benzylpiperidine derivatives
FR2757056B1 (fr)	2003-03-14	Compositions comprenant un derive de dibenzoylmethane, un derive de 1,3,5-triazine et un compose amide et utilisations
UA41928C2 (uk)	2001-10-15	Похідні оксазолідину, спосіб їх одержання, фармацевтична композиція та спосіб її одержання, спосіб лікування захворювань
TW341570B (en)	1998-10-01	Agent for potentiating nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof
ATE285403T1 (de)	2005-01-15	Verfahren zur herstellung von n-((4- phenyl)methylphenyl)piperazinen
DE69701301D1 (de)	2000-03-23	Substituierte Benzylderivate von Polyalkylenpolyaminen und ihre Verwendung in kosmetischen und pharmazeutischen Zusammensetzungen
AU4029395A (en)	1996-06-27	Use of 5-acyl-1,4-dihydropyridines
MY120461A (en)	2005-10-31	Combination of active principles, in particular of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia.
NZ336033A (en)	2000-12-22	4-substituted 1-phenylalkyl-1,2,3,6-tetrahydropyridines for treating alzheimer's disease
MX9801493A (es)	1998-08-30	Amidas del acido fluorbutenoico.