IS2757B - Aðferð til að framleiða bíkalútamíð og aðferð til að hreinsa milliefni fyrir það - Google Patents

Aðferð til að framleiða bíkalútamíð og aðferð til að hreinsa milliefni fyrir það

Info

Publication number
IS2757B
IS2757B IS8459A IS8459A IS2757B IS 2757 B IS2757 B IS 2757B IS 8459 A IS8459 A IS 8459A IS 8459 A IS8459 A IS 8459A IS 2757 B IS2757 B IS 2757B
Authority
IS
Iceland
Prior art keywords
compound
formula
crystals
reacting
bicalutamide
Prior art date
Application number
IS8459A
Other languages
English (en)
Other versions
IS8459A (is
Inventor
Tetsuya Shintaku
Tadashi Katsura
Kiyoshi Sugi
Nobushige Itaya
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of IS8459A publication Critical patent/IS8459A/is
Publication of IS2757B publication Critical patent/IS2757B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IS8459A 2003-10-16 2006-05-11 Aðferð til að framleiða bíkalútamíð og aðferð til að hreinsa milliefni fyrir það IS2757B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003357038A JP4322621B2 (ja) 2003-10-16 2003-10-16 ４’−シアノ−３−［（４−フルオロフェニル）スルホニル］−２−ヒドロキシ−２−メチル−３’−トリフルオロメチルプロピオンアニリドの製造方法
PCT/JP2004/015669 WO2005037777A1 (ja) 2003-10-16 2004-10-15 ビカルタミドの製造方法及びその中間体の精製方法

Publications (2)

Publication Number Publication Date
IS8459A IS8459A (is) 2006-05-11
IS2757B true IS2757B (is) 2011-10-15

Family

ID=34463235

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8459A IS2757B (is) 2003-10-16 2006-05-11 Aðferð til að framleiða bíkalútamíð og aðferð til að hreinsa milliefni fyrir það

Country Status (15)

Country Link
US (1) US20060183934A1 (is)
EP (1) EP1679306B1 (is)
JP (1) JP4322621B2 (is)
KR (1) KR101126948B1 (is)
AT (1) ATE461170T1 (is)
AU (1) AU2004282077A1 (is)
BR (1) BRPI0415347A (is)
CA (1) CA2542788C (is)
DE (1) DE602004026088D1 (is)
ES (1) ES2341008T3 (is)
IL (1) IL174781A (is)
IS (1) IS2757B (is)
NZ (1) NZ546466A (is)
WO (1) WO2005037777A1 (is)
ZA (1) ZA200603289B (is)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1775285T3 (da) * 2004-07-14 2011-11-21 Sumitomo Chemical Co Fremgangsmåde til krystallisation af bicalutamid
JP2008534575A (ja) * 2005-03-29 2008-08-28 ユーエスヴィー リミテッド ビカルタミドの調製のための新規プロセス
CA2513356A1 (en) * 2005-07-26 2007-01-26 Apotex Pharmachem Inc. Process for production of bicalutamide
CZ299577B6 (cs) * 2005-12-20 2008-09-03 Interpharma Praha, A. S. Zpusob výroby vysoce cistého 4-kyano-3-trifluoromethyl-N-(3-p-fluorfenylsulfonyl-2-hydroxy-2-methylpropionyl) anilinu
AU2006329551A1 (en) 2005-12-27 2007-07-05 Dabur Pharma Limited An improved process for preparation of Bicalutamide
CN105541680B (zh) * 2016-02-16 2017-12-22 重庆硕奥科技有限公司 一种比卡鲁胺的合成方法
CN106748884B (zh) * 2016-12-13 2021-08-20 山西振东制药股份有限公司 一种比卡鲁胺中间体的制备方法
CN106831509B (zh) * 2017-02-07 2018-05-18 西北师范大学 一种比卡鲁胺的合成方法
CN106905265A (zh) * 2017-03-09 2017-06-30 常州沃腾化工科技有限公司 N‑[4‑氰基‑3‑（三氟甲基）苯基]‑2,3‑环氧‑2‑甲基丙酰胺的制备方法
CN109456227B (zh) * 2018-11-19 2021-11-16 常州新星联生物科技有限公司 一种比卡鲁胺环氧中间体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU223950B1 (hu) 1999-06-10 2005-03-29 Richter Gedeon Vegyészeti Gyár Rt. Eljárás a racém, valamint az R-(-)- és S-(+)-N-[4-ciano-3-(trifluor-metil)-fenil]-3-[(4-fluor-fenil)-szulfonil]-2-hidroxi-2-metil-propánsavamid előállítására
NZ518392A (en) 1999-10-19 2004-02-27 Nobex Corp Methods of asymmetrically synthesizing enantiomers of casodex, its derivatives and intermediates thereof
MXPA03002495A (es) 2000-09-21 2004-05-05 Bristol Myers Squibb Co Proceso para preparacion de compuestos de n-(fenil sustituido)-3-alquil, aril- y heteroarilsulfonil-2-hidroxi-2-alquil- y haloalquilpropanamida.
DE60233526D1 (de) * 2001-12-13 2009-10-08 Sumitomo Chemical Co Bicalutamidkristalle und verfahren zu deren herstellung

Also Published As

Publication number Publication date
WO2005037777A1 (ja) 2005-04-28
IL174781A0 (en) 2006-08-20
KR20060117948A (ko) 2006-11-17
IL174781A (en) 2011-05-31
DE602004026088D1 (de) 2010-04-29
KR101126948B1 (ko) 2012-03-20
IS8459A (is) 2006-05-11
EP1679306A1 (en) 2006-07-12
CA2542788A1 (en) 2005-04-28
ATE461170T1 (de) 2010-04-15
CA2542788C (en) 2012-01-03
BRPI0415347A (pt) 2006-12-05
AU2004282077A1 (en) 2005-04-28
ES2341008T3 (es) 2010-06-14
US20060183934A1 (en) 2006-08-17
NZ546466A (en) 2009-08-28
JP4322621B2 (ja) 2009-09-02
ZA200603289B (en) 2007-07-25
AU2004282077A2 (en) 2005-04-28
EP1679306A4 (en) 2006-10-11
JP2005120024A (ja) 2005-05-12
EP1679306B1 (en) 2010-03-17

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