IS2060B - Aðferð til framleiðslu á hreinu sítalóprami - Google Patents

Aðferð til framleiðslu á hreinu sítalóprami

Info

Publication number: IS2060B
Authority: IS; Iceland
Prior art keywords: citalopram; amide; subjecting; base; optionally
Prior art date: 2000-12-22

Application number

IS5883A

Other languages

English (en)

Other versions

IS5883A (is

Inventor

Villa Marco

Sbrogio Federico

Veneto Favaro

Dancer Robert

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-22

Filing date

2001-03-09

Publication date

2005-11-15

2001-03-09 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2001-06-20 Publication of IS5883A publication Critical patent/IS5883A/is

2005-11-15 Publication of IS2060B publication Critical patent/IS2060B/is

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

IS5883A 2000-12-22 2001-03-09 Aðferð til framleiðslu á hreinu sítalóprami IS2060B (is)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA200001929		2000-12-22

Publications (2)

Publication Number	Publication Date
IS5883A IS5883A (is)	2001-06-20
IS2060B true IS2060B (is)	2005-11-15

Family

ID=8159922

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5883A IS2060B (is)	2000-12-22	2001-03-09	Aðferð til framleiðslu á hreinu sítalóprami

Country Status (43)

Country	Link
US (1)	US6455710B1 (is)
EP (2)	EP1181713B1 (is)
JP (1)	JP3798982B2 (is)
KR (1)	KR100439329B1 (is)
CN (1)	CN1282648C (is)
AR (1)	AR030056A1 (is)
AT (2)	ATE277920T1 (is)
AU (2)	AU2001100405B4 (is)
BE (2)	BE1013212A6 (is)
BG (1)	BG65131B1 (is)
BR (1)	BR0106272A (is)
CA (1)	CA2360303C (is)
CH (1)	CH691535A5 (is)
CZ (1)	CZ292200B6 (is)
DE (2)	DE60105926T2 (is)
DK (1)	DK1181713T3 (is)
EA (1)	EA003581B1 (is)
ES (2)	ES2228824T3 (is)
FI (2)	FI108639B (is)
FR (1)	FR2812877B1 (is)
GB (1)	GB2357763B (is)
GR (1)	GR1003874B (is)
HK (1)	HK1048812B (is)
HR (1)	HRP20020004A2 (is)
HU (2)	HU0101029D0 (is)
IE (1)	IES20010254A2 (is)
IL (1)	IL147226A (is)
IS (1)	IS2060B (is)
IT (1)	ITMI20010602A1 (is)
MX (1)	MXPA01013151A (is)
NL (2)	NL1017525C1 (is)
NO (1)	NO20011271A (is)
NZ (1)	NZ516298A (is)
PL (1)	PL205724B1 (is)
PT (1)	PT1181713E (is)
SE (1)	SE517623C2 (is)
SG (1)	SG167655A1 (is)
SI (1)	SI1181713T1 (is)
SK (2)	SK286283B6 (is)
TR (1)	TR200201166T1 (is)
UA (1)	UA71634C2 (is)
WO (1)	WO2001045483A2 (is)
ZA (1)	ZA200110179B (is)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
IL145615A0 (en) *	1999-04-14	2002-06-30	Lundbeck & Co As H	Method for the preparation of citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
GB2360281B (en)	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
NZ519739A (en)	1999-12-28	2004-03-26	H	Method for the preparation of citalopram
PT1246813E (pt)	1999-12-30	2004-02-27	Lundbeck & Co As H	Metodo para a preparacao de citalopram
WO2001051477A1 (en)	2000-01-14	2001-07-19	H. Lundbeck A/S	Method for the preparation of 5-cyanophthalide
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
SK14602002A3 (sk)	2000-03-13	2003-02-04	H. Lundbeck A/S	Spôsob výroby citalopramu a medziprodukty
BR0109364A (pt)	2000-03-13	2002-12-24	Lundbeck & Co As H	Métodos para fabricação de citalopram através de alquilação escalonada de 5-substituìda 1- (4-fluorofenil) - 1,3- diidroisobenzofuranos e citalopram
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
IL151488A0 (en)	2000-03-14	2003-04-10	Lundbeck & Co As H	Method for the preparation of citalopram
TR200202168T2 (tr) *	2000-03-16	2002-12-23	H. Lundbeck A/S	5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en)	2000-08-18	2005-09-25	Lundbeck & Co As H	Method for the preparation of citalopram
JP2003519121A (ja)	2000-12-28	2003-06-17	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法
GB0105627D0 (en) *	2001-03-07	2001-04-25	Cipla Ltd	Preparation of phthalanes
HRP20030811A2 (en) *	2001-03-09	2005-08-31	Ranbaxy Laboratories Limited	Process for the preparation of citalopram
US6967259B2 (en) *	2001-09-24	2005-11-22	Pharmachem Technologies Limited	Process for the preparation of Citalopram intermediate
CA2465186A1 (en) *	2001-11-08	2003-05-15	Sepracor, Inc.	Methods for treating depression and other cns disorders using enantiomerically enriched desmethyl- and didesmethyl-metabolites of citalopram
WO2003057132A2 (en) *	2002-01-07	2003-07-17	Sun Pharmaceutical Industries Limited	Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
GB0204607D0 (en) *	2002-02-27	2002-04-10	Matrix Lab Ltd	Process
MXPA05005155A (es) *	2002-11-15	2005-07-22	Akzo Nobel Nv	Tratamiento de purificacion/decoloracion para nitrilos grasos.
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
EP1486492A3 (en) *	2003-06-10	2005-02-23	Sun Pharmaceuticals Industries Ltd.	A process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran.
WO2005042473A1 (en) *	2003-10-28	2005-05-12	Wockhardt Limited	Improved process for the manufacture of citalopram hydrobromide
CN100569765C (zh)	2003-12-19	2009-12-16	杭州民生药业集团有限公司	西酞普兰中间体晶体碱
TWI358407B (en) *	2005-06-22	2012-02-21	Lundbeck & Co As H	Crystalline base of escitalopram and orodispersibl
CN114763343B (zh) *	2021-01-14	2026-02-10	浙江华海药业股份有限公司	一种西酞普兰或s-西酞普兰的纯化方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE536169C (de) *	1926-08-21	1931-10-20	British Dyestuffs Corp Ltd	Verfahren zur Gewinnung von tertiaeren aromatischen Aminen aus ihren Gemischen mit sekundaeren und primaeren aromatischen Aminen
US1992111A (en) *	1931-06-20	1935-02-19	Du Pont	Separation of secondary and tertiary amines
DE1032261B (de) *	1955-03-08	1958-06-19	Leda Chemicals Ltd	Verfahren zur Abtrennung sekundaerer Amine aus einer primaeres und sekundaeres Amin enthaltenden Mischung
GB1143703A (is)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
US4302399A (en) *	1978-09-28	1981-11-24	Dynapol	Acetylation of crude reaction products containing polymeric colorants
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
US4943591A (en)	1984-10-17	1990-07-24	Glaxo Group Limited	Dichloroaniline derivatives
DE3926765A1 (de)	1989-08-12	1991-02-14	Hoechst Ag	Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DK213290D0 (da) *	1990-09-06	1990-09-06	Lundbeck & Co As H	Treatment of cerebrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
EP0993524B1 (en) *	1997-06-30	2002-11-20	Beloit Technologies, Inc.	Method and apparatus for the high speed application of coating to a traveling paper web
JP3526581B2 (ja)	1997-07-08	2004-05-17	ハー・ルンドベック・アクティーゼルスカブ	シタロプラムの製造方法
UA62985C2 (en)	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
CN1286687A (zh) *	1997-11-11	2001-03-07	H·隆德贝克有限公司	制备西酞普兰的方法
WO2000023431A1 (en) *	1998-10-20	2000-04-27	H. Lundbeck A/S	Method for the preparation of citalopram
HK1043130B (zh)	1998-12-23	2005-03-04	H‧隆德贝克有限公司	制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
IL145615A0 (en)	1999-04-14	2002-06-30	Lundbeck & Co As H	Method for the preparation of citalopram
ITMI991579A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991486A1 (it) *	1999-07-06	2001-01-06	Vis Farmaceutici S P A	Processo per la sintesi di citalopram
GB2360281B (en)	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
NL1017415C1 (nl)	2000-02-24	2001-05-18	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
GB2357762B (en) *	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
IL144816A (en)	2000-08-18	2005-09-25	Lundbeck & Co As H	Method for the preparation of citalopram
JP2003519121A (ja)	2000-12-28	2003-06-17	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法

2001
- 2001-03-07 TR TR2002/01166T patent/TR200201166T1/xx unknown
- 2001-03-07 AT AT01913726T patent/ATE277920T1/de not_active IP Right Cessation
- 2001-03-07 JP JP2001546230A patent/JP3798982B2/ja not_active Expired - Fee Related
- 2001-03-07 PL PL353398A patent/PL205724B1/pl not_active IP Right Cessation
- 2001-03-07 AU AU2001100405A patent/AU2001100405B4/en not_active Ceased
- 2001-03-07 HK HK03100966.7A patent/HK1048812B/zh not_active IP Right Cessation
- 2001-03-07 SK SK4-2005A patent/SK286283B6/sk not_active IP Right Cessation
- 2001-03-07 SK SK1848-2001A patent/SK284428B6/sk not_active IP Right Cessation
- 2001-03-07 AU AU39201/01A patent/AU3920101A/en active Pending
- 2001-03-07 CA CA002360303A patent/CA2360303C/en not_active Expired - Fee Related
- 2001-03-07 KR KR10-2001-7016686A patent/KR100439329B1/ko not_active Expired - Fee Related
- 2001-03-07 EP EP01913726A patent/EP1181713B1/en not_active Expired - Lifetime
- 2001-03-07 WO PCT/DK2001/000147 patent/WO2001045483A2/en not_active Ceased
- 2001-03-07 ES ES01913726T patent/ES2228824T3/es not_active Expired - Lifetime
- 2001-03-07 PT PT01913726T patent/PT1181713E/pt unknown
- 2001-03-07 IL IL147226A patent/IL147226A/en not_active IP Right Cessation
- 2001-03-07 BR BR0106272-7A patent/BR0106272A/pt not_active Application Discontinuation
- 2001-03-07 EP EP04004482A patent/EP1462447A3/en not_active Withdrawn
- 2001-03-07 MX MXPA01013151A patent/MXPA01013151A/es active IP Right Grant
- 2001-03-07 HR HR20020004A patent/HRP20020004A2/hr not_active Application Discontinuation
- 2001-03-07 SG SG200504030-8A patent/SG167655A1/en unknown
- 2001-03-07 SI SI200130238T patent/SI1181713T1/xx unknown
- 2001-03-07 EA EA200200018A patent/EA003581B1/ru not_active IP Right Cessation
- 2001-03-07 DE DE60105926T patent/DE60105926T2/de not_active Expired - Lifetime
- 2001-03-07 CN CNB018011225A patent/CN1282648C/zh not_active Expired - Lifetime
- 2001-03-07 NL NL1017525A patent/NL1017525C1/nl not_active IP Right Cessation
- 2001-03-07 DK DK01913726T patent/DK1181713T3/da active
- 2001-03-09 HU HU0101029A patent/HU0101029D0/hu unknown
- 2001-03-09 IS IS5883A patent/IS2060B/is unknown
- 2001-03-12 GB GB0105983A patent/GB2357763B/en not_active Revoked
- 2001-03-12 CZ CZ2001890A patent/CZ292200B6/cs not_active IP Right Cessation
- 2001-03-13 FI FI20010500A patent/FI108639B/fi not_active IP Right Cessation
- 2001-03-13 NO NO20011271A patent/NO20011271A/no not_active IP Right Cessation
- 2001-03-14 FR FR0103455A patent/FR2812877B1/fr not_active Expired - Fee Related
- 2001-03-15 IE IE20010254A patent/IES20010254A2/en not_active IP Right Cessation
- 2001-03-15 AR ARP010101209A patent/AR030056A1/es not_active Application Discontinuation
- 2001-03-16 GR GR20010100132A patent/GR1003874B/el not_active IP Right Cessation
- 2001-03-16 DE DE10112829A patent/DE10112829C1/de not_active Expired - Fee Related
- 2001-03-21 AT AT0020801U patent/AT4367U1/de not_active IP Right Cessation
- 2001-03-22 CH CH00545/01A patent/CH691535A5/de not_active IP Right Cessation
- 2001-03-22 IT IT2001MI000602A patent/ITMI20010602A1/it unknown
- 2001-03-22 BE BE2001/0188A patent/BE1013212A6/fr not_active IP Right Cessation
- 2001-06-22 NL NL1018360A patent/NL1018360C1/nl not_active IP Right Cessation
- 2001-06-26 BE BE2001/0435A patent/BE1013213A6/fr not_active IP Right Cessation
- 2001-07-03 UA UA2002021552A patent/UA71634C2/uk unknown
- 2001-07-05 HU HU0102817A patent/HUP0102817A3/hu unknown
- 2001-07-26 FI FI20011577A patent/FI109024B/fi active
- 2001-07-27 ES ES200101762A patent/ES2170732B2/es not_active Expired - Fee Related
- 2001-09-14 SE SE0103045A patent/SE517623C2/sv not_active IP Right Cessation
- 2001-12-10 BG BG106203A patent/BG65131B1/bg unknown
- 2001-12-11 ZA ZA200110179A patent/ZA200110179B/xx unknown
- 2001-12-20 NZ NZ516298A patent/NZ516298A/xx unknown
2002
- 2002-01-08 US US10/046,126 patent/US6455710B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FR2812877B1 (fr)	2003-04-04
DE60105926D1 (de)	2004-11-04
WO2001045483A2 (en)	2001-06-28
TR200201166T1 (tr)	2002-10-21
IS5883A (is)	2001-06-20
HK1048812A1 (en)	2003-04-17
HRP20020004A2 (en)	2003-04-30
SE0103045D0 (sv)	2001-09-14
NO20011271D0 (no)	2001-03-13
BG65131B1 (bg)	2007-03-30
ZA200110179B (en)	2002-12-11
MXPA01013151A (es)	2002-08-12
IL147226A0 (en)	2002-08-14
PL205724B1 (pl)	2010-05-31
ES2170732A1 (es)	2002-08-01
DE60105926T2 (de)	2005-11-24
HU0101029D0 (en)	2001-05-28
AU2001100405A4 (en)	2001-11-01
HU0102817D0 (en)	2001-09-28
ITMI20010602A0 (it)	2001-03-22
DK1181713T3 (da)	2005-01-31
CN1282648C (zh)	2006-11-01
BR0106272A (pt)	2004-06-15
NO312462B1 (no)	2002-05-13
GB2357763B (en)	2002-01-16
SE0103045L (sv)	2002-06-23
SI1181713T1 (en)	2005-02-28
AT4367U1 (de)	2001-06-25
EA003581B1 (ru)	2003-06-26
CZ2001890A3 (cs)	2002-08-14
NL1017525C1 (nl)	2001-04-26
IES20010254A2 (en)	2002-03-06
SE517623C2 (sv)	2002-06-25
CZ292200B6 (cs)	2003-08-13
ES2228824T3 (es)	2005-04-16
CH691535A5 (de)	2001-08-15
ITMI20010602A1 (it)	2002-09-22
CA2360303C (en)	2003-08-12
BE1013212A6 (fr)	2001-10-02
KR20020065345A (ko)	2002-08-13
PT1181713E (pt)	2005-02-28
NO20011271A (no)	2002-05-13
FI20011577A0 (fi)	2001-07-26
DE10112829C1 (de)	2002-07-25
NZ516298A (en)	2002-12-20
US20020120005A1 (en)	2002-08-29
ES2170732B2 (es)	2003-09-16
HUP0102817A3 (en)	2003-07-28
WO2001045483A3 (en)	2001-12-27
PL353398A1 (en)	2003-11-17
SG167655A1 (en)	2011-01-28
SK18482001A3 (sk)	2002-05-09
NL1018360C1 (nl)	2001-10-04
FR2812877A1 (fr)	2002-02-15
BE1013213A6 (fr)	2001-10-02
GB0105983D0 (en)	2001-05-02
HUP0102817A2 (hu)	2001-12-28
FI109024B (fi)	2002-05-15
FI20010500A0 (fi)	2001-03-13
GB2357763A (en)	2001-07-04
BG106203A (bg)	2002-08-30
EP1181713B1 (en)	2004-09-29
EP1181713A2 (en)	2002-02-27
JP3798982B2 (ja)	2006-07-19
AU2001100405B4 (en)	2002-03-21
EP1462447A3 (en)	2004-11-17
HK1048812B (zh)	2007-06-01
SK284428B6 (sk)	2005-04-01
IL147226A (en)	2006-04-10
SK286283B6 (sk)	2008-06-06
EA200200018A1 (ru)	2002-04-25
US6455710B1 (en)	2002-09-24
UA71634C2 (uk)	2004-12-15
GR1003874B (el)	2002-04-24
KR100439329B1 (ko)	2004-07-07
AR030056A1 (es)	2003-08-13
ATE277920T1 (de)	2004-10-15
AU3920101A (en)	2001-07-03
EP1462447A2 (en)	2004-09-29
JP2003517484A (ja)	2003-05-27
CN1366525A (zh)	2002-08-28
FI108639B (fi)	2002-02-28
CA2360303A1 (en)	2001-06-28

Publication	Publication Date	Title
IS5883A (is)	2001-06-20	Aðferð til framleiðslu á hreinu sítalóprami
BG106219A (bg)	2002-08-30	Метод за получаване на чист циталопрам
ATE441627T1 (de)	2009-09-15	Verfahren zur herstellung von valsartan
DE50306068D1 (de)	2007-02-01	Verfahren zum herstellen von salzen des tolperison
ATE299862T1 (de)	2005-08-15	Verfahren zur herstellung von ketiminen
US6147215A (en)	2000-11-14	Process for producing 1-chlorocarbonyl-4-piperidinopiperidine or hydrochloride thereof
JP2005536557A5 (is)	2006-09-14
JP2767295B2 (ja)	1998-06-18	インドール―３―カルボニトリル化合物の製造方法
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