IS5640A - Ný kristalla form af Bensímídazól efnasambandi gegn veirum - Google Patents

Ný kristalla form af Bensímídazól efnasambandi gegn veirum

Info

Publication number: IS5640A
Authority: IS; Iceland
Prior art keywords: crystalline form; antiviral compound; new crystalline; benzimidazole antiviral; benzimidazole
Prior art date: 1998-04-07

Application number

IS5640A

Other languages

English (en)

Inventor

William Lancaster Robert

Allen Schmitt Eric

Howard Carter Barry

Neal Glover Bobby

Huang Lian-Feng

Todd Long Stacey

Catherine Rizzolio Michele

Riddle Sickles Barry

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-07

Filing date

2000-09-26

Publication date

2000-09-26

2000-09-26 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

2000-09-26 Publication of IS5640A publication Critical patent/IS5640A/is

Links

HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 title 1
230000000840 anti-viral effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Virology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

IS5640A 1998-04-07 2000-09-26 Ný kristalla form af Bensímídazól efnasambandi gegn veirum IS5640A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9807354.7A GB9807354D0 (en)	1998-04-07	1998-04-07	Antiviral compound
PCT/EP1999/002214 WO1999051618A1 (en)	1998-04-07	1999-04-01	Novel crystalline forms of an antiviral benzimidazole compound

Publications (1)

Publication Number	Publication Date
IS5640A true IS5640A (is)	2000-09-26

Family

ID=10829932

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5640A IS5640A (is)	1998-04-07	2000-09-26	Ný kristalla form af Bensímídazól efnasambandi gegn veirum

Country Status (28)

Country	Link
US (9)	US6469160B1 (is)
EP (1)	EP1071693B1 (is)
JP (1)	JP2002510703A (is)
KR (1)	KR20010074472A (is)
CN (1)	CN1303390A (is)
AP (1)	AP2000001947A0 (is)
AT (1)	ATE261452T1 (is)
AU (1)	AU752877B2 (is)
BR (1)	BR9909474A (is)
CA (1)	CA2327494C (is)
DE (1)	DE69915461T2 (is)
EA (1)	EA002970B1 (is)
EE (1)	EE04120B1 (is)
ES (1)	ES2216503T3 (is)
GB (1)	GB9807354D0 (is)
HR (1)	HRP20000669A2 (is)
HU (1)	HUP0101669A3 (is)
ID (1)	ID27109A (is)
IL (1)	IL138697A0 (is)
IS (1)	IS5640A (is)
NO (1)	NO20005005L (is)
NZ (1)	NZ507173A (is)
PL (1)	PL343397A1 (is)
SK (1)	SK14832000A3 (is)
TR (1)	TR200002860T2 (is)
WO (1)	WO1999051618A1 (is)
YU (1)	YU60900A (is)
ZA (1)	ZA200005153B (is)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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GB9807355D0 (en)	1998-04-07	1998-06-03	Glaxo Group Ltd	Antiviral compound
GB9807354D0 (en) *	1998-04-07	1998-06-03	Glaxo Group Ltd	Antiviral compound
GB0008939D0 (en)	2000-04-11	2000-05-31	Glaxo Group Ltd	Process for preparing substituted benzimidazole compounds
EP2767539B1 (en)	2002-05-16	2017-07-12	Janssen Sciences Ireland UC	Pseudopolymorphic forms of a HIV protease inhibitor
ES2370829T3 (es) *	2004-06-02	2011-12-23	Sandoz Ag	Producto intermedio de meropenem en forma cristalina.
WO2007004230A2 (en) *	2005-07-05	2007-01-11	Hetero Drugs Limited	A novel process for the preparation of didanosine using novel intermediates
EP1906937B1 (en) *	2005-07-22	2016-10-19	Rubicon Research Pvt Ltd.	Novel dispersible tablet composition
AU2006298881A1 (en) *	2005-09-21	2007-04-12	4Sc Ag	Sulphonylpyrrole hydrochloride salts as histone deacetylases inhibitors
NZ567357A (en) *	2005-10-31	2011-05-27	Janssen Pharmaceutica Nv	Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
CA2656057C (en) *	2006-06-16	2012-10-02	H. Lundbeck A/S	Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
US7919598B2 (en) *	2006-06-28	2011-04-05	Bristol-Myers Squibb Company	Crystal structures of SGLT2 inhibitors and processes for preparing same
KR20090084891A (ko) *	2006-10-27	2009-08-05	시그날 파마소티칼 엘엘씨	4-[9-(테트라하이드로-퓨란-3-일)-8-(2,4,6-트리플루오로-페닐아미노)-9ｈ-퓨린-2-일아미노]-사이클로헥산-1-올을 포함하는 고체 형태들, 이들의 조성물들 및 이들의 용도
EP2085397A1 (en) *	2008-01-21	2009-08-05	Esteve Quimica, S.A.	Crystalline form of abacavir
US7935817B2 (en) *	2008-03-31	2011-05-03	Apotex Pharmachem Inc.	Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
AR071318A1 (es) *	2008-04-15	2010-06-09	Basilea Pharmaceutica Ag	Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
US8097719B2 (en) *	2008-07-15	2012-01-17	Genesen Labs	Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
KR101043794B1 (ko) *	2009-04-13	2011-06-27	청우산업 주식회사	황토판재로 제공되는 기능성 황토방
AU2011224287B2 (en)	2010-03-12	2015-03-26	Omeros Corporation	PDE10 inhibitors and related compositions and methods
WO2012030957A2 (en) *	2010-09-01	2012-03-08	Arena Pharmaceuticals, Inc.	Non-hygroscopic salts of 5-ht2c agonists
US8940707B2 (en)	2010-10-28	2015-01-27	Viropharma Incorporated	Maribavir isomers, compositions, methods of making and methods of using
US8541391B2 (en)	2010-10-28	2013-09-24	Viropharma Incorporated	Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole
US8546344B2 (en)	2010-10-28	2013-10-01	Viropharma Incorporated	Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
JP2014530805A (ja) *	2011-09-30	2014-11-20	スンシネルアケプハルマカンパニーリミテッド	アジルサルタンの結晶形並びにその製造及び使用
NZ716494A (en)	2014-04-28	2017-07-28	Omeros Corp	Processes and intermediates for the preparation of a pde10 inhibitor
NZ630803A (en) *	2014-04-28	2016-03-31	Omeros Corp	Optically active pde10 inhibitor
JP2018513153A (ja)	2015-04-24	2018-05-24	オメロスコーポレーション	Ｐｄｅ１０インヒビターならびに関連する組成物および方法
WO2017079678A1 (en)	2015-11-04	2017-05-11	Omeros Corporation	Solid state forms of a pde10 inhibitor
EP3870292A4 (en)	2018-10-26	2022-11-09	The Research Foundation for The State University of New York	COMBINATION OF SEROTONIN-SPECIFIC RESUPPUT INHIBITOR AND SEROTONIN 1A RECEPTOR PARTIAL AGONIST TO REDUCE L-DOPA-INDUCED DYSKINESIA
CN111303230B (zh) *	2020-03-09	2021-07-13	中国食品药品检定研究院	一种黄体酮共晶物及其制备方法和用途
HUE072879T2 (hu)	2022-10-12	2025-12-28	Takeda Pharmaceuticals Co	A Maribavir elkészítési eljárása

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3399987A (en) *	1965-08-02	1968-09-03	United States Borax Chem	2-alkylaminobenzimidazoles as herbicides
CH443777A (de) *	1965-08-06	1968-02-15	Agripat Sa	Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
US3655901A (en) *	1970-07-30	1972-04-11	Merck & Co Inc	Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
SE9003151D0 (sv) *	1990-10-02	1990-10-02	Medivir Ab	Nucleoside derivatives
US5248672A (en) *	1990-11-01	1993-09-28	The Regents Of The University Of Michigan	Polysubstituted benzimidazole nucleosides as antiviral agents
WO1994008456A1 (en) *	1992-10-21	1994-04-28	The Regents Of The University Of Michigan	Polysubstituted benzimidazoles as antiviral agents
GB9413724D0 (en) *	1994-07-07	1994-08-24	Wellcome Found	Therapeutic nucleosides
GB9600143D0 (en)	1996-01-05	1996-03-06	Wellcome Found	Therapeutic compounds
GB9807355D0 (en)	1998-04-07	1998-06-03	Glaxo Group Ltd	Antiviral compound
GB9807354D0 (en) *	1998-04-07	1998-06-03	Glaxo Group Ltd	Antiviral compound

1998
- 1998-04-07 GB GBGB9807354.7A patent/GB9807354D0/en not_active Ceased
1999
- 1999-04-01 AP APAP/P/2000/001947A patent/AP2000001947A0/en unknown
- 1999-04-01 WO PCT/EP1999/002214 patent/WO1999051618A1/en not_active Ceased
- 1999-04-01 EP EP99917935A patent/EP1071693B1/en not_active Expired - Lifetime
- 1999-04-01 ES ES99917935T patent/ES2216503T3/es not_active Expired - Lifetime
- 1999-04-01 HU HU0101669A patent/HUP0101669A3/hu unknown
- 1999-04-01 EE EEP200000584A patent/EE04120B1/xx not_active IP Right Cessation
- 1999-04-01 HR HR20000669A patent/HRP20000669A2/hr not_active Application Discontinuation
- 1999-04-01 IL IL13869799A patent/IL138697A0/xx unknown
- 1999-04-01 SK SK1483-2000A patent/SK14832000A3/sk unknown
- 1999-04-01 EA EA200000911A patent/EA002970B1/ru not_active IP Right Cessation
- 1999-04-01 JP JP2000542339A patent/JP2002510703A/ja active Pending
- 1999-04-01 YU YU60900A patent/YU60900A/sh unknown
- 1999-04-01 AT AT99917935T patent/ATE261452T1/de not_active IP Right Cessation
- 1999-04-01 ID IDW20002036A patent/ID27109A/id unknown
- 1999-04-01 CA CA2327494A patent/CA2327494C/en not_active Expired - Lifetime
- 1999-04-01 CN CN99806894A patent/CN1303390A/zh active Pending
- 1999-04-01 DE DE69915461T patent/DE69915461T2/de not_active Expired - Lifetime
- 1999-04-01 AU AU36034/99A patent/AU752877B2/en not_active Ceased
- 1999-04-01 US US09/647,962 patent/US6469160B1/en not_active Expired - Lifetime
- 1999-04-01 TR TR2000/02860T patent/TR200002860T2/xx unknown
- 1999-04-01 BR BR9909474-6A patent/BR9909474A/pt not_active IP Right Cessation
- 1999-04-01 NZ NZ507173A patent/NZ507173A/en unknown
- 1999-04-01 PL PL99343397A patent/PL343397A1/xx unknown
- 1999-04-01 KR KR1020007011089A patent/KR20010074472A/ko not_active Withdrawn
2000
- 2000-09-26 IS IS5640A patent/IS5640A/is unknown
- 2000-09-26 ZA ZA200005153A patent/ZA200005153B/en unknown
- 2000-10-04 NO NO20005005A patent/NO20005005L/no not_active Application Discontinuation
2001
- 2001-10-29 US US10/007,272 patent/US7297683B2/en not_active Expired - Fee Related
2007
- 2007-10-25 US US11/924,204 patent/US7714123B2/en not_active Expired - Fee Related
2010
- 2010-03-26 US US12/732,302 patent/US20100179101A1/en not_active Abandoned
2011
- 2011-01-25 US US13/012,924 patent/US9163052B2/en not_active Expired - Fee Related
2013
- 2013-02-01 US US13/756,612 patent/US20130261294A1/en not_active Abandoned
2015
- 2015-10-12 US US14/880,600 patent/US20160030460A1/en not_active Abandoned
2016
- 2016-09-19 US US15/268,949 patent/US20170002035A1/en not_active Abandoned
2017
- 2017-10-05 US US15/725,785 patent/US20180044366A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20020177703A1 (en)	2002-11-28
SK14832000A3 (sk)	2001-07-10
US7714123B2 (en)	2010-05-11
IL138697A0 (en)	2001-10-31
HRP20000669A2 (en)	2001-08-31
ES2216503T3 (es)	2004-10-16
US20180044366A1 (en)	2018-02-15
NO20005005D0 (no)	2000-10-04
YU60900A (sh)	2003-07-07
EP1071693B1 (en)	2004-03-10
JP2002510703A (ja)	2002-04-09
EA200000911A1 (ru)	2001-04-23
US20160030460A1 (en)	2016-02-04
DE69915461T2 (de)	2005-03-03
US20080103186A1 (en)	2008-05-01
US20130261294A1 (en)	2013-10-03
KR20010074472A (ko)	2001-08-04
ID27109A (id)	2001-03-01
ATE261452T1 (de)	2004-03-15
ZA200005153B (en)	2001-09-26
US6469160B1 (en)	2002-10-22
CN1303390A (zh)	2001-07-11
EE200000584A (et)	2002-04-15
AP2000001947A0 (en)	2000-12-31
AU752877B2 (en)	2002-10-03
GB9807354D0 (en)	1998-06-03
US20100179101A1 (en)	2010-07-15
HUP0101669A3 (en)	2003-07-28
WO1999051618A1 (en)	1999-10-14
US9163052B2 (en)	2015-10-20
CA2327494A1 (en)	1999-10-14
EE04120B1 (et)	2003-08-15
TR200002860T2 (tr)	2000-12-21
AU3603499A (en)	1999-10-25
CA2327494C (en)	2010-10-26
BR9909474A (pt)	2000-12-19
US7297683B2 (en)	2007-11-20
PL343397A1 (en)	2001-08-13
NO20005005L (no)	2000-12-06
NZ507173A (en)	2003-07-25
HUP0101669A2 (hu)	2001-10-28
EP1071693A1 (en)	2001-01-31
US20170002035A1 (en)	2017-01-05
DE69915461D1 (de)	2004-04-15
US20110118203A1 (en)	2011-05-19
EA002970B1 (ru)	2002-12-26

Publication	Publication Date	Title
IS5640A (is)	2000-09-26	Ný kristalla form af Bensímídazól efnasambandi gegn veirum
DK1149090T3 (da)	2003-06-30	Ny krystallinsk form af kaliumsalt af (S)-omeprazol
DK0991641T3 (da)	2003-05-19	Krystallinsk form af omeprazol-natriumsalt
DK1107980T3 (da)	2003-04-22	Krystallinske former af EtO2C-CH2-(R)Cgl-Aze-Pab-OH
DK1056444T3 (da)	2007-03-12	Stabile formede partikler af krystallinske organiske forbindelser
DK1421939T5 (da)	2011-07-18	Præparat med opretholdt frigivelse af en makrolidforbindelse såsom tacrolimus
DK1077943T3 (da)	2009-03-16	Heterocykliske inhibitorer af p38
DK1451192T3 (da)	2011-04-04	Ny krystallinsk forbindelse
DK1289992T3 (da)	2006-07-03	Ny krystallingsk form af en triazolo(4,5-d)pyrimidinforbindelse
IS5841A (is)	2001-09-14	Kristallaður basi af sítalóprami
DK1098906T3 (da)	2010-03-29	Peptidanaloger af PACAP
NO20020030L (no)	2002-03-05	Krystallinske 1-metylkarbapenemforbindelser
PT1082191E (pt)	2002-09-30	Estrutura cinematica paralela de uma maquina-ferramenta
NO20005795D0 (no)	2000-11-16	Antivirale forbindelser
DK1274427T3 (da)	2005-12-27	Formulering af substituerede benzimidazoler
DK1280803T3 (da)	2005-01-24	Krystallinsk form II af cabergolin
IS6215A (is)	2001-12-27	Að mestu leyti kristallað form af melagatrani
DK1155050T3 (da)	2007-06-11	Fremstilling af polyolefin
IS5821A (is)	2001-01-23	Kristalluð form af ósanetant
IS5155A (is)	2000-02-22	Fjölgervingur af zópólrestat mónóhýdrati
EE200100017A (et)	2002-06-17	N-tert-butüülhüdroksüülamiini uued soolad
DK1088010T3 (da)	2004-07-12	Fremstilling af polyolefiner
PT1175417E (pt)	2004-04-30	Compostos substituidos de benzolactamas
DK0996646T3 (da)	2003-10-06	Syntese af forgrenet polyolefin
DK1140984T3 (da)	2003-05-26	Selektive inhibitorer af MMP-12