DK1056444T3 - Stabile formede partikler af krystallinske organiske forbindelser - Google Patents

Stabile formede partikler af krystallinske organiske forbindelser

Info

Publication number
DK1056444T3
DK1056444T3 DK99902729T DK99902729T DK1056444T3 DK 1056444 T3 DK1056444 T3 DK 1056444T3 DK 99902729 T DK99902729 T DK 99902729T DK 99902729 T DK99902729 T DK 99902729T DK 1056444 T3 DK1056444 T3 DK 1056444T3
Authority
DK
Denmark
Prior art keywords
organic compounds
shaped particles
crystalline organic
stable shaped
stable
Prior art date
Application number
DK99902729T
Other languages
English (en)
Inventor
Abraham Gomez
John Claude Savoir
Juan Angeles Uribe
Gyves Aurelio De
Original Assignee
John Claude Savoir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21853984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1056444(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by John Claude Savoir filed Critical John Claude Savoir
Application granted granted Critical
Publication of DK1056444T3 publication Critical patent/DK1056444T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
DK99902729T 1998-02-25 1999-02-10 Stabile formede partikler af krystallinske organiske forbindelser DK1056444T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/030,388 US6287693B1 (en) 1998-02-25 1998-02-25 Stable shaped particles of crystalline organic compounds
PCT/IB1999/000233 WO1999043304A1 (en) 1998-02-25 1999-02-10 Stable shaped particles of crystalline organic compounds

Publications (1)

Publication Number Publication Date
DK1056444T3 true DK1056444T3 (da) 2007-03-12

Family

ID=21853984

Family Applications (3)

Application Number Title Priority Date Filing Date
DK06022834T DK1772141T3 (da) 1998-02-25 1999-02-10 Fremgangsmåde til gennemföring af krystallisation i fast tilstand
DK09156268.6T DK2085075T3 (da) 1998-02-25 1999-02-10 Stabile formede partikler af krystallinske organiske forbindelser
DK99902729T DK1056444T3 (da) 1998-02-25 1999-02-10 Stabile formede partikler af krystallinske organiske forbindelser

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK06022834T DK1772141T3 (da) 1998-02-25 1999-02-10 Fremgangsmåde til gennemföring af krystallisation i fast tilstand
DK09156268.6T DK2085075T3 (da) 1998-02-25 1999-02-10 Stabile formede partikler af krystallinske organiske forbindelser

Country Status (34)

Country Link
US (7) US6287693B1 (da)
EP (4) EP2085075B1 (da)
JP (2) JP4885357B2 (da)
KR (1) KR100726315B1 (da)
CN (2) CN1146407C (da)
AR (3) AR018107A1 (da)
AT (2) ATE345779T1 (da)
AU (1) AU747779B2 (da)
BR (1) BR9908156A (da)
CA (1) CA2319176C (da)
CL (1) CL2010001333A1 (da)
CY (1) CY1118522T1 (da)
CZ (1) CZ301042B6 (da)
DE (2) DE69940684D1 (da)
DK (3) DK1772141T3 (da)
EE (1) EE05019B1 (da)
ES (3) ES2609284T3 (da)
HU (1) HUP0101271A3 (da)
ID (1) ID26523A (da)
IL (2) IL137970A0 (da)
MY (1) MY138375A (da)
NO (1) NO331804B1 (da)
NZ (1) NZ505987A (da)
PE (1) PE20000393A1 (da)
PL (1) PL196369B1 (da)
PT (1) PT2085075T (da)
RU (1) RU2225708C2 (da)
SA (1) SA99200098B1 (da)
TR (1) TR200002462T2 (da)
TW (1) TWI256308B (da)
UA (1) UA73470C2 (da)
UY (1) UY25404A1 (da)
WO (1) WO1999043304A1 (da)
ZA (1) ZA991058B (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287693B1 (en) * 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US7700645B2 (en) 2002-05-16 2010-04-20 Tibotec Pharmaceuticals Ltd. Pseudopolymorphic forms of a HIV protease inhibitor
US20040028746A1 (en) * 2002-08-06 2004-02-12 Sonke Svenson Crystalline drug particles prepared using a controlled precipitation (recrystallization) process
US20040028747A1 (en) * 2002-08-06 2004-02-12 Tucker Christopher J. Crystalline drug particles prepared using a controlled precipitation process
US7589082B2 (en) 2003-06-13 2009-09-15 Skendi Finance Ltd Pharmaceutical formulation for contraception and hormone-replacement therapy
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
WO2005009375A2 (en) * 2003-07-22 2005-02-03 Baxter International Inc. Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
RU2331410C2 (ru) * 2003-12-04 2008-08-20 Пфайзер Продактс Инк. Способ получения фармацевтических мультичастиц
EP1718258B1 (en) 2004-02-23 2009-03-25 Euro-Celtique S.A. Abuse resistance opioid transdermal delivery device
RU2008100543A (ru) * 2005-06-17 2009-07-27 БАСФ Акциенгезельшафт (DE) Способ получения усилителей эффекта отбеливания
CA2718943A1 (en) * 2008-03-26 2009-10-01 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
CN102056611A (zh) * 2008-04-14 2011-05-11 Posi维森纳里解决方案有限责任公司 用于获得不同的治疗适应症所需要的血浆孕酮水平的方法和药物组合物
FR2939326B1 (fr) * 2008-12-10 2011-04-01 Univ Joseph Fourier Procede et dispositif de controle d'une cristallisation.
AU2009352681B2 (en) 2009-09-17 2014-11-20 Upsher-Smith Laboratories, Llc A sustained-release product comprising a combination of a non-opioid amine and a non-steroidal anti -inflammatory drug
UY33103A (es) * 2009-12-15 2011-07-29 Techsphere S A De C V Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico
WO2011115066A1 (ja) * 2010-03-19 2011-09-22 第一三共株式会社 ジアミン誘導体の結晶およびその製造方法
US9351924B2 (en) 2011-03-11 2016-05-31 Snu R&Db Foundation Drug delivery system including laminated structure
KR101314126B1 (ko) 2011-03-11 2013-10-04 서울대학교산학협력단 다면체 형상의 약물 전달 시스템
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
EA035469B1 (ru) 2013-03-15 2020-06-22 Инсайт Холдингс Корпорейшн Трициклические гетероциклы как ингибиторы белков бэт
US9309246B2 (en) 2013-12-19 2016-04-12 Incyte Corporation Tricyclic heterocycles as BET protein inhibitors
SMT202000133T1 (it) 2014-04-23 2020-05-08 Incyte Corp 1h-pirrolo[2,3-c]piridin-7(6h)-oni e pirazolo[3,4-c]piridin-7(6h)-oni come inibitori di proteine bet
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
ITUB20153652A1 (it) * 2015-09-16 2017-03-16 Fatro Spa Microsfere contenenti lattoni macrociclici antielminitici
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
CN109715625B (zh) 2016-06-20 2022-04-19 因赛特公司 Bet抑制剂的结晶固体形式
PL236889B1 (pl) * 2017-10-03 2021-02-22 Univ Warszawski Medyczny Nowa forma krystaliczna bezwodnego 17-β-estradiolu, sposób jej otrzymywania oraz kompozycja farmaceutyczna zawierająca nową formę krystaliczną bezwodnego 17-β-estradiolu i jej zastosowanie
EP3542786A1 (en) * 2018-03-21 2019-09-25 ITF Research Pharma, S.L.U. Progesterone intravaginal devices
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2447362A (en) 1945-11-01 1948-08-17 Rca Corp Production of crystals
US3800038A (en) * 1972-04-21 1974-03-26 Biolog Concepts Inc Uterine administraton of eutectic solid solutions of steroid hormones in a steroidal lipid carrier
US4230621A (en) * 1978-05-01 1980-10-28 E. R. Squibb & Sons, Inc. Steroid derivatives and their use in radioimmunoassays
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
IL63968A (en) 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
JPS5799562A (en) 1980-12-12 1982-06-21 Nippon Shinyaku Co Ltd Preparation of microcrystal
DE3049196A1 (de) 1980-12-24 1982-07-29 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von granulaten aus organischen in form einer schmelze vorliegenden stoffen
US4447426A (en) * 1982-01-18 1984-05-08 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method
JPS58143832A (ja) 1982-02-22 1983-08-26 Yoshiaki Kawashima 結晶性化学物質の球状化再結晶法
DE3213025C2 (de) 1982-04-02 1997-06-12 Fischer Karl Ind Gmbh Verfahren zur Nachkondensation von Polykondensaten
GB8618847D0 (en) * 1986-08-01 1986-09-10 Smith Kline French Lab Pharmaceutical formulations
JPH0714625B2 (ja) 1987-03-30 1995-02-22 呉羽化学工業株式会社 高結晶化ポリアリ−レンチオエ−テル成形物
US4897307A (en) 1987-08-11 1990-01-30 The Dow Chemical Company Process for the solvent-induced crystallization of amorphous poly(etheretherketone)-type polymers and the article formed thereby
US4948871A (en) 1987-09-28 1990-08-14 Asahi Kasei Kogyo Kabushiki Kaisha Method for producing a crystallized aromatic polycarbonate, and a crystallized aromatic polycarbonate obtained thereby
US4919899A (en) 1988-02-29 1990-04-24 Herrmann Frederick T Crystal growth apparatus
YU120988A (en) * 1988-06-23 1990-06-30 Lek Tovarna Farmacevtskih Process for preparing new dispersion pills of cimetidine
IT1230566B (it) 1988-10-17 1991-10-28 Vectorpharma Int Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione
US5360478A (en) 1989-10-16 1994-11-01 Phasex Corporation Gas anti-solvent recrystallization process
FR2663223B1 (fr) 1990-06-14 1994-12-02 Af Aplicaciones Far Lab Forme galenique parenterale.
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
JPH04305226A (ja) 1991-01-25 1992-10-28 Senichi Masuda ガス中窒素酸化物の低減方法
SE9101090D0 (sv) * 1991-04-11 1991-04-11 Astra Ab Process for conditioning of water-soluble substances
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
US5391810A (en) 1991-05-23 1995-02-21 Ajinomoto Co., Inc. Method of crystallizing α-L-aspartyl-L-phenylalanine methyl ester
DE4130173A1 (de) 1991-09-11 1993-03-18 Bayer Ag Pharmazeutische zubereitungen mit einer speziellen kristallmodifikation des 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridindicarbonsaeure-isopropyl-(2-methoxyethyl)-esters
DE4218929C1 (da) 1992-06-10 1993-09-09 Deutsche Bundesbahn, Vertreten Durch Das Bundesbahn-Zentralamt Minden (Westf.), 4950 Minden, De
US5290913A (en) 1992-10-08 1994-03-01 Carrier Vibrating Equipment, Inc. Method and apparatus for the heat treatment of material
US5558678A (en) 1992-11-13 1996-09-24 Karl Fischer Industrieanlagen Gmbh Process and apparatus for continuous crystallization of plastic granules
US5686092A (en) 1992-11-24 1997-11-11 Alkermes Controlled Therapeutics Inc. Ii Growth promoters for animals
WO1994020116A1 (en) * 1993-03-10 1994-09-15 University Of Alabama Research Foundation Artificial primers for glycogen synthesis
US5409605A (en) * 1993-08-05 1995-04-25 Chemical Lime Company Apparatus and method for treating waste sludge
JPH0757558A (ja) * 1993-08-09 1995-03-03 Showa Electric Wire & Cable Co Ltd 耐熱絶縁電線
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
US5849651A (en) * 1995-06-01 1998-12-15 Kabushiki Kaisha Toshiba Reversible thermal recording medium
JPH0957558A (ja) * 1995-08-18 1997-03-04 Nabeya Iron & Tool Works Ltd スライド装置
JPH09227558A (ja) * 1996-02-28 1997-09-02 Fujisawa Pharmaceut Co Ltd チアゾール化合物の安定な結晶およびその製造方法
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
JP2000143832A (ja) 1998-11-10 2000-05-26 Toppan Printing Co Ltd 高剛性を有するフィルムまたはシート

Also Published As

Publication number Publication date
EE200000492A (et) 2002-02-15
PL196369B1 (pl) 2007-12-31
AU2293699A (en) 1999-09-15
AU747779B2 (en) 2002-05-23
CN100528140C (zh) 2009-08-19
NZ505987A (en) 2003-07-25
HUP0101271A2 (hu) 2001-09-28
DK2085075T3 (da) 2017-01-23
CY1118522T1 (el) 2017-07-12
TWI256308B (en) 2006-06-11
PL343170A1 (en) 2001-07-30
US6737081B2 (en) 2004-05-18
DK1772141T3 (da) 2009-07-20
JP2002504507A (ja) 2002-02-12
US6528094B1 (en) 2003-03-04
WO1999043304A1 (en) 1999-09-02
US6638536B2 (en) 2003-10-28
EP2319497A1 (en) 2011-05-11
EP1772141B1 (en) 2009-04-01
SA99200098B1 (ar) 2006-04-26
IL137970A (en) 2006-10-05
US7427413B2 (en) 2008-09-23
KR20010034540A (ko) 2001-04-25
US6287693B1 (en) 2001-09-11
US20020168395A1 (en) 2002-11-14
US6537580B1 (en) 2003-03-25
ATE345779T1 (de) 2006-12-15
JP2011241220A (ja) 2011-12-01
UA73470C2 (uk) 2005-08-15
HK1155384A1 (en) 2012-05-18
CA2319176C (en) 2007-09-11
IL137970A0 (en) 2001-10-31
DE69934099T2 (de) 2007-06-21
US20040166164A1 (en) 2004-08-26
US20030191101A1 (en) 2003-10-09
HUP0101271A3 (en) 2002-10-28
CZ20003047A3 (cs) 2000-11-15
NO20004241L (no) 2000-08-24
CN1291887A (zh) 2001-04-18
EP1772141A1 (en) 2007-04-11
PE20000393A1 (es) 2000-05-04
ES2609284T3 (es) 2017-04-19
EP1056444A1 (en) 2000-12-06
AR077168A2 (es) 2011-08-10
EP2085075A1 (en) 2009-08-05
TR200002462T2 (tr) 2000-11-21
CN1146407C (zh) 2004-04-21
ATE427102T1 (de) 2009-04-15
AR077167A2 (es) 2011-08-10
NO20004241D0 (no) 2000-08-24
UY25404A1 (es) 1999-05-14
US20030147964A1 (en) 2003-08-07
EE05019B1 (et) 2008-06-16
DE69940684D1 (de) 2009-05-14
EP2085075B1 (en) 2016-09-28
CA2319176A1 (en) 1999-09-02
HK1036017A1 (en) 2001-12-21
PT2085075T (pt) 2017-01-04
RU2225708C2 (ru) 2004-03-20
NO331804B1 (no) 2012-04-10
ES2324366T3 (es) 2009-08-05
US6663895B2 (en) 2003-12-16
AR018107A1 (es) 2001-10-31
MY138375A (en) 2009-05-29
EP1056444B1 (en) 2006-11-22
DE69934099D1 (de) 2007-01-04
JP4885357B2 (ja) 2012-02-29
CZ301042B6 (cs) 2009-10-21
BR9908156A (pt) 2000-10-31
EP2319497B1 (en) 2012-08-22
ES2275334T3 (es) 2007-06-01
KR100726315B1 (ko) 2007-06-11
ID26523A (id) 2001-01-11
CN1524608A (zh) 2004-09-01
ZA991058B (en) 1999-08-11
CL2010001333A1 (es) 2011-04-25

Similar Documents

Publication Publication Date Title
NO20004241D0 (no) Stabile formede partikler av krystallinske organiske forbindelser
DK1107980T3 (da) Krystallinske former af EtO2C-CH2-(R)Cgl-Aze-Pab-OH
IS5640A (is) Ný kristalla form af Bensímídazól efnasambandi gegn veirum
DK1169314T3 (da) Krystallinsk base af citalopram
DK1005328T3 (da) Sammensætning omfattende findelte krystallinske partikler af budesonid
DK1149090T3 (da) Ny krystallinsk form af kaliumsalt af (S)-omeprazol
DK0991641T3 (da) Krystallinsk form af omeprazol-natriumsalt
DK1064298T3 (da) Inhibitorer af caspaser
DK1289992T3 (da) Ny krystallingsk form af en triazolo(4,5-d)pyrimidinforbindelse
DE60025198D1 (de) Stabile biozidale zusammensetzung
DK1077943T3 (da) Heterocykliske inhibitorer af p38
IS7007A (is) Kristallaform af asiþrómýsíni
DK1522539T3 (da) Krystallinsk komposition indeholdende excitalopram
DK1272489T3 (da) Fremgangsmåde til præparation af cabergolins krystallinske form I
DK1280803T3 (da) Krystallinsk form II af cabergolin
ID26700A (id) Senyawa-senyawa azapolisiklik yang bercampur dengan aril
ID30516A (id) Senyawa-senyawa (aminoiminometil atau aminometil) benzoheteroaril tersubstitusi
DK1155050T3 (da) Fremstilling af polyolefin
IS6215A (is) Að mestu leyti kristallað form af melagatrani
IS5821A (is) Kristalluð form af ósanetant
DE69903701D1 (de) Stabile 3-Isothiazolonzusammensetzungen
DK1088010T3 (da) Fremstilling af polyolefiner
PT1175417E (pt) Compostos substituidos de benzolactamas
DK1175420T3 (da) Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater
DK1140984T3 (da) Selektive inhibitorer af MMP-12