NO20005005L - Nye krystallinske former av en antiviral benzimidazolforbindelse - Google Patents

Nye krystallinske former av en antiviral benzimidazolforbindelse

Info

Publication number
NO20005005L
NO20005005L NO20005005A NO20005005A NO20005005L NO 20005005 L NO20005005 L NO 20005005L NO 20005005 A NO20005005 A NO 20005005A NO 20005005 A NO20005005 A NO 20005005A NO 20005005 L NO20005005 L NO 20005005L
Authority
NO
Norway
Prior art keywords
crystalline forms
new crystalline
benzimidazole compound
antiviral
antiviral benzimidazole
Prior art date
Application number
NO20005005A
Other languages
English (en)
Other versions
NO20005005D0 (no
Inventor
Barry Howard Carter
Bobby Neal Glover
Lian-Feng Huang
Stacey Todd Long
Michele Catherine Rizzolio
Barry Riddle Sickles
Robert William Lancaster
Eric Allen Schmitt
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20005005D0 publication Critical patent/NO20005005D0/no
Publication of NO20005005L publication Critical patent/NO20005005L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO20005005A 1998-04-07 2000-10-04 Nye krystallinske former av en antiviral benzimidazolforbindelse NO20005005L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9807354.7A GB9807354D0 (en) 1998-04-07 1998-04-07 Antiviral compound
PCT/EP1999/002214 WO1999051618A1 (en) 1998-04-07 1999-04-01 Novel crystalline forms of an antiviral benzimidazole compound

Publications (2)

Publication Number Publication Date
NO20005005D0 NO20005005D0 (no) 2000-10-04
NO20005005L true NO20005005L (no) 2000-12-06

Family

ID=10829932

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005005A NO20005005L (no) 1998-04-07 2000-10-04 Nye krystallinske former av en antiviral benzimidazolforbindelse

Country Status (28)

Country Link
US (9) US6469160B1 (no)
EP (1) EP1071693B1 (no)
JP (1) JP2002510703A (no)
KR (1) KR20010074472A (no)
CN (1) CN1303390A (no)
AP (1) AP2000001947A0 (no)
AT (1) ATE261452T1 (no)
AU (1) AU752877B2 (no)
BR (1) BR9909474A (no)
CA (1) CA2327494C (no)
DE (1) DE69915461T2 (no)
EA (1) EA002970B1 (no)
EE (1) EE04120B1 (no)
ES (1) ES2216503T3 (no)
GB (1) GB9807354D0 (no)
HR (1) HRP20000669A2 (no)
HU (1) HUP0101669A3 (no)
ID (1) ID27109A (no)
IL (1) IL138697A0 (no)
IS (1) IS5640A (no)
NO (1) NO20005005L (no)
NZ (1) NZ507173A (no)
PL (1) PL343397A1 (no)
SK (1) SK14832000A3 (no)
TR (1) TR200002860T2 (no)
WO (1) WO1999051618A1 (no)
YU (1) YU60900A (no)
ZA (1) ZA200005153B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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GB9807355D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB9807354D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB0008939D0 (en) 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
EP2767539B1 (en) 2002-05-16 2017-07-12 Janssen Sciences Ireland UC Pseudopolymorphic forms of a HIV protease inhibitor
ES2370829T3 (es) * 2004-06-02 2011-12-23 Sandoz Ag Producto intermedio de meropenem en forma cristalina.
WO2007004230A2 (en) * 2005-07-05 2007-01-11 Hetero Drugs Limited A novel process for the preparation of didanosine using novel intermediates
EP1906937B1 (en) * 2005-07-22 2016-10-19 Rubicon Research Pvt Ltd. Novel dispersible tablet composition
AU2006298881A1 (en) * 2005-09-21 2007-04-12 4Sc Ag Sulphonylpyrrole hydrochloride salts as histone deacetylases inhibitors
NZ567357A (en) * 2005-10-31 2011-05-27 Janssen Pharmaceutica Nv Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
CA2656057C (en) * 2006-06-16 2012-10-02 H. Lundbeck A/S Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
US7919598B2 (en) * 2006-06-28 2011-04-05 Bristol-Myers Squibb Company Crystal structures of SGLT2 inhibitors and processes for preparing same
KR20090084891A (ko) * 2006-10-27 2009-08-05 시그날 파마소티칼 엘엘씨 4-[9-(테트라하이드로-퓨란-3-일)-8-(2,4,6-트리플루오로-페닐아미노)-9ｈ-퓨린-2-일아미노]-사이클로헥산-1-올을 포함하는 고체 형태들, 이들의 조성물들 및 이들의 용도
EP2085397A1 (en) * 2008-01-21 2009-08-05 Esteve Quimica, S.A. Crystalline form of abacavir
US7935817B2 (en) * 2008-03-31 2011-05-03 Apotex Pharmachem Inc. Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
AR071318A1 (es) * 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
US8097719B2 (en) * 2008-07-15 2012-01-17 Genesen Labs Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
KR101043794B1 (ko) * 2009-04-13 2011-06-27 청우산업 주식회사 황토판재로 제공되는 기능성 황토방
AU2011224287B2 (en) 2010-03-12 2015-03-26 Omeros Corporation PDE10 inhibitors and related compositions and methods
WO2012030957A2 (en) * 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
US8940707B2 (en) 2010-10-28 2015-01-27 Viropharma Incorporated Maribavir isomers, compositions, methods of making and methods of using
US8541391B2 (en) 2010-10-28 2013-09-24 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole
US8546344B2 (en) 2010-10-28 2013-10-01 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
JP2014530805A (ja) * 2011-09-30 2014-11-20 スンシネ ルアケ プハルマ カンパニー リミテッド アジルサルタンの結晶形並びにその製造及び使用
NZ716494A (en) 2014-04-28 2017-07-28 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
NZ630803A (en) * 2014-04-28 2016-03-31 Omeros Corp Optically active pde10 inhibitor
JP2018513153A (ja) 2015-04-24 2018-05-24 オメロス コーポレーション Ｐｄｅ１０インヒビターならびに関連する組成物および方法
WO2017079678A1 (en) 2015-11-04 2017-05-11 Omeros Corporation Solid state forms of a pde10 inhibitor
EP3870292A4 (en) 2018-10-26 2022-11-09 The Research Foundation for The State University of New York COMBINATION OF SEROTONIN-SPECIFIC RESUPPUT INHIBITOR AND SEROTONIN 1A RECEPTOR PARTIAL AGONIST TO REDUCE L-DOPA-INDUCED DYSKINESIA
CN111303230B (zh) * 2020-03-09 2021-07-13 中国食品药品检定研究院 一种黄体酮共晶物及其制备方法和用途
HUE072879T2 (hu) 2022-10-12 2025-12-28 Takeda Pharmaceuticals Co A Maribavir elkészítési eljárása

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3399987A (en) * 1965-08-02 1968-09-03 United States Borax Chem 2-alkylaminobenzimidazoles as herbicides
CH443777A (de) * 1965-08-06 1968-02-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
US3655901A (en) * 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
SE9003151D0 (sv) * 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
US5248672A (en) * 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
WO1994008456A1 (en) * 1992-10-21 1994-04-28 The Regents Of The University Of Michigan Polysubstituted benzimidazoles as antiviral agents
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
GB9600143D0 (en) 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
GB9807355D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB9807354D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound

Also Published As

Publication number Publication date
US20020177703A1 (en) 2002-11-28
SK14832000A3 (sk) 2001-07-10
US7714123B2 (en) 2010-05-11
IL138697A0 (en) 2001-10-31
HRP20000669A2 (en) 2001-08-31
ES2216503T3 (es) 2004-10-16
US20180044366A1 (en) 2018-02-15
NO20005005D0 (no) 2000-10-04
YU60900A (sh) 2003-07-07
EP1071693B1 (en) 2004-03-10
JP2002510703A (ja) 2002-04-09
EA200000911A1 (ru) 2001-04-23
US20160030460A1 (en) 2016-02-04
DE69915461T2 (de) 2005-03-03
US20080103186A1 (en) 2008-05-01
US20130261294A1 (en) 2013-10-03
KR20010074472A (ko) 2001-08-04
ID27109A (id) 2001-03-01
ATE261452T1 (de) 2004-03-15
ZA200005153B (en) 2001-09-26
US6469160B1 (en) 2002-10-22
CN1303390A (zh) 2001-07-11
EE200000584A (et) 2002-04-15
AP2000001947A0 (en) 2000-12-31
AU752877B2 (en) 2002-10-03
GB9807354D0 (en) 1998-06-03
US20100179101A1 (en) 2010-07-15
HUP0101669A3 (en) 2003-07-28
WO1999051618A1 (en) 1999-10-14
US9163052B2 (en) 2015-10-20
CA2327494A1 (en) 1999-10-14
EE04120B1 (et) 2003-08-15
TR200002860T2 (tr) 2000-12-21
AU3603499A (en) 1999-10-25
CA2327494C (en) 2010-10-26
BR9909474A (pt) 2000-12-19
US7297683B2 (en) 2007-11-20
PL343397A1 (en) 2001-08-13
IS5640A (is) 2000-09-26
NZ507173A (en) 2003-07-25
HUP0101669A2 (hu) 2001-10-28
EP1071693A1 (en) 2001-01-31
US20170002035A1 (en) 2017-01-05
DE69915461D1 (de) 2004-04-15
US20110118203A1 (en) 2011-05-19
EA002970B1 (ru) 2002-12-26

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Legal Events

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