IS5723A - Nituroxíðs efnasmíða latar (Synthase Inhibitors) - Google Patents

Nituroxíðs efnasmíða latar (Synthase Inhibitors)

Info

Publication number: IS5723A
Authority: IS; Iceland
Prior art keywords: nitric oxide; oxide synthase; synthase inhibitors; inhibitors; nitric
Prior art date: 1998-05-30

Application number

IS5723A

Other languages

English (en)

Other versions

IS2442B (is

Inventor

John Beswick Paul

Kleanthous Savvas

John Young Robert

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-30

Filing date

2000-11-21

Publication date

2000-11-21

2000-11-21 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

2000-11-21 Publication of IS5723A publication Critical patent/IS5723A/is

2008-11-15 Publication of IS2442B publication Critical patent/IS2442B/is

Links

239000000236 nitric oxide synthase inhibitor Substances 0.000 title 1
CSYSULGPHGCBQD-UHFFFAOYSA-N s-ethylisothiouronium diethylphosphate Chemical compound CCSC(N)=N.CCOP(O)(=O)OCC CSYSULGPHGCBQD-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Neurology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IS5723A 1998-05-30 2000-11-21 Hindrar á nituroxíðþétta IS2442B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9811599.1A GB9811599D0 (en)	1998-05-30	1998-05-30	Nitric oxide synthase inhibitors
PCT/EP1999/003583 WO1999062875A1 (en)	1998-05-30	1999-05-27	Nitric oxide synthase inhibitors

Publications (2)

Publication Number	Publication Date
IS5723A true IS5723A (is)	2000-11-21
IS2442B IS2442B (is)	2008-11-15

Family

ID=10832929

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5723A IS2442B (is)	1998-05-30	2000-11-21	Hindrar á nituroxíðþétta

Country Status (30)

Country	Link
US (2)	US6355689B1 (is)
EP (1)	EP1084104B1 (is)
JP (1)	JP3839256B2 (is)
KR (1)	KR20010043920A (is)
CN (1)	CN1218940C (is)
AP (1)	AP1382A (is)
AT (1)	ATE245142T1 (is)
AU (1)	AU757042B2 (is)
BR (1)	BR9910849A (is)
CA (1)	CA2333322C (is)
CZ (1)	CZ297473B6 (is)
DE (1)	DE69909625T2 (is)
DK (1)	DK1084104T3 (is)
EA (1)	EA003026B1 (is)
EE (1)	EE04149B1 (is)
ES (1)	ES2203147T3 (is)
GB (1)	GB9811599D0 (is)
HU (1)	HUP0102472A3 (is)
ID (1)	ID26790A (is)
IL (1)	IL139697A (is)
IS (1)	IS2442B (is)
NO (1)	NO20006044L (is)
NZ (1)	NZ508222A (is)
PL (1)	PL194784B1 (is)
PT (1)	PT1084104E (is)
RS (1)	RS49984B (is)
SK (1)	SK18052000A3 (is)
TR (1)	TR200003539T2 (is)
WO (1)	WO1999062875A1 (is)
ZA (1)	ZA200006847B (is)

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PE20081889A1 (es)	2007-03-23	2009-03-05	Smithkline Beecham Corp	Indol carboxamidas como inhibidores de ikk2
BRPI0912267A2 (pt)	2008-05-23	2015-10-13	Amira Pharmaceuticals Inc	sal farmaceuticamente aceitável, composição farmacêutica, artigo de fabricação, métodos para tratar asma, rinite alérgica, doença, lesões gástricas e dor, métodos para prevenir broncoconstrição e rinite alérgica, uso de um sal farmaceuticamente aceitável, e, processo para a preparação de um sal farmaceuticamente aceitável.
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JP5502077B2 (ja)	2008-06-05	2014-05-28	グラクソグループリミテッド	新規な化合物
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1998
- 1998-05-30 GB GBGB9811599.1A patent/GB9811599D0/en not_active Ceased
1999
- 1999-05-27 BR BR9910849-6A patent/BR9910849A/pt not_active Application Discontinuation
- 1999-05-27 WO PCT/EP1999/003583 patent/WO1999062875A1/en not_active Ceased
- 1999-05-27 NZ NZ508222A patent/NZ508222A/xx unknown
- 1999-05-27 AT AT99926397T patent/ATE245142T1/de not_active IP Right Cessation
- 1999-05-27 IL IL13969799A patent/IL139697A/xx not_active IP Right Cessation
- 1999-05-27 JP JP2000552087A patent/JP3839256B2/ja not_active Expired - Fee Related
- 1999-05-27 RS YUP-746/00A patent/RS49984B/sr unknown
- 1999-05-27 DE DE69909625T patent/DE69909625T2/de not_active Expired - Lifetime
- 1999-05-27 CA CA002333322A patent/CA2333322C/en not_active Expired - Fee Related
- 1999-05-27 KR KR1020007013451A patent/KR20010043920A/ko not_active Ceased
- 1999-05-27 ES ES99926397T patent/ES2203147T3/es not_active Expired - Lifetime
- 1999-05-27 PL PL344368A patent/PL194784B1/pl unknown
- 1999-05-27 CN CNB998068578A patent/CN1218940C/zh not_active Expired - Fee Related
- 1999-05-27 EP EP99926397A patent/EP1084104B1/en not_active Expired - Lifetime
- 1999-05-27 DK DK99926397T patent/DK1084104T3/da active
- 1999-05-27 SK SK1805-2000A patent/SK18052000A3/sk unknown
- 1999-05-27 AP APAP/P/2000/001998A patent/AP1382A/en active
- 1999-05-27 CZ CZ20004450A patent/CZ297473B6/cs not_active IP Right Cessation
- 1999-05-27 EA EA200001122A patent/EA003026B1/ru not_active IP Right Cessation
- 1999-05-27 PT PT99926397T patent/PT1084104E/pt unknown
- 1999-05-27 HU HU0102472A patent/HUP0102472A3/hu unknown
- 1999-05-27 AU AU43671/99A patent/AU757042B2/en not_active Ceased
- 1999-05-27 ID IDW20002495A patent/ID26790A/id unknown
- 1999-05-27 US US09/701,473 patent/US6355689B1/en not_active Expired - Lifetime
- 1999-05-27 TR TR2000/03539T patent/TR200003539T2/xx unknown
- 1999-05-27 EE EEP200000716A patent/EE04149B1/xx not_active IP Right Cessation
2000
- 2000-11-21 IS IS5723A patent/IS2442B/is unknown
- 2000-11-22 ZA ZA200006847A patent/ZA200006847B/en unknown
- 2000-11-29 NO NO20006044A patent/NO20006044L/no not_active Application Discontinuation
2001
- 2001-11-26 US US09/994,969 patent/US6495606B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK1084104T3 (da)	2003-10-27
GB9811599D0 (en)	1998-07-29
CN1218940C (zh)	2005-09-14
ID26790A (id)	2001-02-08
DE69909625T2 (de)	2004-06-24
JP3839256B2 (ja)	2006-11-01
PL344368A1 (en)	2001-11-05
RS49984B (sr)	2008-09-29
EE04149B1 (et)	2003-10-15
AP1382A (en)	2005-04-01
EA003026B1 (ru)	2002-12-26
IL139697A (en)	2005-12-18
AU757042B2 (en)	2003-01-30
CA2333322C (en)	2008-01-22
EA200001122A1 (ru)	2001-06-25
EP1084104B1 (en)	2003-07-16
JP2002516901A (ja)	2002-06-11
ATE245142T1 (de)	2003-08-15
ES2203147T3 (es)	2004-04-01
CZ297473B6 (cs)	2006-12-13
PT1084104E (pt)	2003-11-28
IS2442B (is)	2008-11-15
CA2333322A1 (en)	1999-12-09
HUP0102472A2 (hu)	2002-03-28
IL139697A0 (en)	2002-02-10
SK18052000A3 (sk)	2001-06-11
HUP0102472A3 (en)	2002-12-28
KR20010043920A (ko)	2001-05-25
BR9910849A (pt)	2001-02-20
WO1999062875A1 (en)	1999-12-09
YU74600A (sh)	2002-12-10
EP1084104A1 (en)	2001-03-21
NO20006044D0 (no)	2000-11-29
ZA200006847B (en)	2001-11-22
AP2000001998A0 (en)	2000-12-31
NO20006044L (no)	2001-01-29
CN1303367A (zh)	2001-07-11
AU4367199A (en)	1999-12-20
TR200003539T2 (tr)	2001-06-21
NZ508222A (en)	2003-02-28
CZ20004450A3 (en)	2001-05-16
HK1034241A1 (en)	2001-10-19
US6355689B1 (en)	2002-03-12
US6495606B1 (en)	2002-12-17
PL194784B1 (pl)	2007-07-31
EE200000716A (et)	2002-04-15
DE69909625D1 (en)	2003-08-21

Publication	Publication Date	Title
IS5723A (is)	2000-11-21	Nituroxíðs efnasmíða latar (Synthase Inhibitors)
EE04013B1 (et)	2003-04-15	Lämmastikoksiidi süntaasi inhibiitorid
GB0031179D0 (en)	2001-01-31	Nitric oxide synthase inhibitors
DE69906554D1 (de)	2003-05-08	P38 inhibitoren
EE200000519A (et)	2002-02-15	Lämmastikoksiidi süntaasi inhibiitoritena toimivad halogeenitud amidinoaminohappederivaadid
EP1324759A4 (en)	2004-05-12	NF - G (K) B INHIBITORS
NO20031140L (no)	2003-05-08	2-amino-2-alkyl-5-hepten- og heptynsyrederivater som er anvendbare som nitrogenoksydsyntase-inhibitorer
NO20003814D0 (no)	2000-07-25	Trombininhibitorer
EE9900474A (et)	2000-06-15	Amidiini derivaadid lämmastikoksiidi süntaasi inhibiitoritena
MA24854A1 (fr)	1999-12-31	Inhibiteurs d'oxyde nitrique synthase
AU2002350575A1 (en)	2003-01-08	Selective neuronal nitric oxide synthase inhibitors
HRP980381B1 (en)	2002-02-28	Nitric oxide synthase inhibitors
SI1084104T1 (en)	2003-12-31	Nitric oxide synthase inhibitors
DE69930852D1 (de)	2006-05-24	Prenyltransferase-inhibitoren
SI0958277T1 (en)	2002-06-30	Nitric oxide synthase inhibitors
GB0031177D0 (en)	2001-01-31	Nitric oxide synthase inhibitors
GB9918076D0 (en)	1999-10-06	Microencapsulated nitric oxide synthase source
GB0016172D0 (en)	2000-08-23	Microencapsulated nitric oxide synthase source
SE9802118D0 (sv)	1998-06-15	Mycobacterial inhibitors