IS7021A - Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun - Google Patents

Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun

Info

Publication number
IS7021A
IS7021A IS7021A IS7021A IS7021A IS 7021 A IS7021 A IS 7021A IS 7021 A IS7021 A IS 7021A IS 7021 A IS7021 A IS 7021A IS 7021 A IS7021 A IS 7021A
Authority
IS
Iceland
Prior art keywords
production
heteroaryl derivatives
disorders
disorder
new heteroaryl
Prior art date
Application number
IS7021A
Other languages
English (en)
Other versions
IS2425B (is
Inventor
Rottländer Mario
Knud Moltzen Ejner
Mikkelsen Ivan
Ruhland Thomas
Andersen Kim
Krog-Jensen Christian
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of IS7021A publication Critical patent/IS7021A/is
Publication of IS2425B publication Critical patent/IS2425B/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS7021A 2001-06-29 2003-11-10 Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun IS2425B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101036 2001-06-29
PCT/DK2002/000435 WO2003002556A1 (en) 2001-06-29 2002-06-27 Novel heteroaryl derivatives, their preparation and use

Publications (2)

Publication Number Publication Date
IS7021A true IS7021A (is) 2003-11-10
IS2425B IS2425B (is) 2008-10-15

Family

ID=8160598

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7021A IS2425B (is) 2001-06-29 2003-11-10 Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun

Country Status (26)

Country Link
US (2) US20040248883A1 (is)
EP (1) EP1399438B1 (is)
JP (1) JP2004535449A (is)
KR (1) KR20040019026A (is)
CN (1) CN1310909C (is)
AT (1) ATE312094T1 (is)
AU (1) AU2002344949B2 (is)
BG (1) BG108531A (is)
BR (1) BR0210401A (is)
CA (1) CA2451228A1 (is)
CZ (1) CZ2004156A3 (is)
DE (1) DE60207857T2 (is)
DK (1) DK1399438T3 (is)
EA (1) EA006203B1 (is)
ES (1) ES2252471T3 (is)
HU (1) HUP0400344A2 (is)
IL (1) IL158828A0 (is)
IS (1) IS2425B (is)
MX (1) MXPA03011769A (is)
NO (1) NO326514B1 (is)
NZ (1) NZ529460A (is)
PL (1) PL365249A1 (is)
SI (1) SI1399438T1 (is)
SK (1) SK652004A3 (is)
UA (1) UA75407C2 (is)
WO (1) WO2003002556A1 (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2451229C (en) * 2001-06-29 2009-02-10 H. Lundbeck A/S Indole derivatives
DK1408976T5 (da) * 2001-07-20 2011-01-10 Psychogenics Inc Behandling af ADHD (Attention deficit hyperactivity disorder)
DE112004001191B4 (de) * 2003-07-02 2017-11-09 Corus Pharma Inc. Verfahren zur Herstellung des L-Lysin-Salzes von Aztreonam und Verfahren zur Bestimmung des Verunreinigungsgrads in einem amorphen Aztreonam Lysin-Salz
US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
ES2331144T3 (es) 2004-11-26 2009-12-22 Janssen Pharmaceutica Nv Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada.
CN102822167A (zh) 2010-01-04 2012-12-12 埃南蒂亚有限公司 用于制备利伐沙班的方法及其中间体
JP5546678B2 (ja) 2010-04-12 2014-07-09 ロッテ ケミカル コーポレーション チオフェン−縮合環シクロペンタジエニルリガンドを含む遷移金属化合物を使用したポリプロピレンの製造方法
KR100986301B1 (ko) 2010-04-12 2010-10-07 아주대학교산학협력단 테트라하이드로퀴놀린 유도체로부터 유래한 티오펜-축합고리 싸이클로펜타디에닐 4족 금속 화합물 및 이를 이용한 올레핀 중합
JP5567209B2 (ja) 2010-04-12 2014-08-06 ロッテ ケミカル コーポレーション オレフィン重合用担持触媒およびこれを用いたポリオレフィンの製造方法
US8916662B2 (en) 2010-04-12 2014-12-23 Lotte Chemical Corporation Method for preparing olefin-diene copolymer using transition metal compound containing thiophene-fused cyclopentadienyl ligand
JP5567208B2 (ja) 2010-04-12 2014-08-06 ロッテ ケミカル コーポレーション オレフィン重合用触媒組成物およびこれを用いたポリオレフィンの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
CA2451229C (en) 2001-06-29 2009-02-10 H. Lundbeck A/S Indole derivatives

Also Published As

Publication number Publication date
JP2004535449A (ja) 2004-11-25
IS2425B (is) 2008-10-15
CN1520410A (zh) 2004-08-11
CN1310909C (zh) 2007-04-18
SK652004A3 (en) 2004-09-08
AU2002344949B2 (en) 2007-05-24
UA75407C2 (en) 2006-04-17
EA200400102A1 (ru) 2004-04-29
US20080027071A1 (en) 2008-01-31
DK1399438T3 (da) 2006-04-18
EA006203B1 (ru) 2005-10-27
NO20035673D0 (no) 2003-12-18
ES2252471T3 (es) 2006-05-16
CZ2004156A3 (cs) 2004-05-12
BG108531A (bg) 2004-08-31
EP1399438A1 (en) 2004-03-24
BR0210401A (pt) 2004-08-17
NO326514B1 (no) 2008-12-22
WO2003002556A1 (en) 2003-01-09
MXPA03011769A (es) 2004-04-02
US7393845B2 (en) 2008-07-01
US20040248883A1 (en) 2004-12-09
EP1399438B1 (en) 2005-12-07
KR20040019026A (ko) 2004-03-04
NZ529460A (en) 2005-09-30
ATE312094T1 (de) 2005-12-15
CA2451228A1 (en) 2003-01-09
HK1068622A1 (en) 2005-04-29
PL365249A1 (en) 2004-12-27
NO20035673L (no) 2003-12-18
IL158828A0 (en) 2004-05-12
DE60207857D1 (de) 2006-01-12
DE60207857T2 (de) 2006-07-20
HUP0400344A2 (hu) 2004-09-28
SI1399438T1 (sl) 2006-04-30

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