IS7118A - Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfnæmissjúkdómum - Google Patents

Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfnæmissjúkdómum

Info

Publication number: IS7118A
Authority: IS; Iceland
Prior art keywords: sup; sub; alkyl; optionally substituted; thienopyrimidinedione
Prior art date: 2001-07-28

Application number

IS7118A

Other languages

English (en)

Other versions

IS2598B (is

Inventor

Heulwen Reynolds Rachel

Howard Ingall Anthony

Tasneem Rasul Rukhsana

David Guile Simon

Edward Cooper Martin

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-28

Filing date

2004-01-19

Publication date

2004-01-19

2004-01-19 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2004-01-19 Publication of IS7118A publication Critical patent/IS7118A/is

2010-03-15 Publication of IS2598B publication Critical patent/IS2598B/is

Links

208000023275 Autoimmune disease Diseases 0.000 title abstract 2
QAFVXBQPQCSSLI-UHFFFAOYSA-N 1h-thieno[3,2-d]pyrimidine-2,4-dione Chemical compound O=C1NC(=O)NC2=C1SC=C2 QAFVXBQPQCSSLI-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
-1 isoxazolidin-2-ylcarbonyl Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000006413 ring segment Chemical group 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Virology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Transplantation (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Oncology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
AIDS & HIV (AREA)
Neurosurgery (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)

IS7118A 2001-07-28 2004-01-19 Þíenópýrimidíndíón og notkun þeirra í mótun sjálfnæmissjúkdóma IS2598B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0118479.5A GB0118479D0 (en)	2001-07-28	2001-07-28	Novel compounds
PCT/GB2002/003399 WO2003011868A1 (en)	2001-07-28	2002-07-24	Thienopyrimidinediones and their use in the modulation of autoimmune disease

Publications (2)

Publication Number	Publication Date
IS7118A true IS7118A (is)	2004-01-19
IS2598B IS2598B (is)	2010-03-15

Family

ID=9919407

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7118A IS2598B (is)	2001-07-28	2004-01-19	Þíenópýrimidíndíón og notkun þeirra í mótun sjálfnæmissjúkdóma

Country Status (24)

Country	Link
US (2)	US7384950B2 (is)
EP (1)	EP1414825B9 (is)
JP (1)	JP4456364B2 (is)
KR (1)	KR100897469B1 (is)
CN (1)	CN1324033C (is)
AR (1)	AR038000A1 (is)
AT (1)	ATE374204T1 (is)
AU (1)	AU2002319469B2 (is)
BR (1)	BR0211262A (is)
CA (1)	CA2453274A1 (is)
DE (1)	DE60222671T2 (is)
ES (1)	ES2292784T3 (is)
GB (1)	GB0118479D0 (is)
HU (1)	HUP0402336A3 (is)
IL (2)	IL159785A0 (is)
IS (1)	IS2598B (is)
MX (1)	MXPA04000677A (is)
MY (1)	MY138145A (is)
NO (1)	NO328713B1 (is)
NZ (1)	NZ530495A (is)
PL (1)	PL211351B1 (is)
RU (1)	RU2294937C9 (is)
WO (1)	WO2003011868A1 (is)
ZA (1)	ZA200400574B (is)

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SE9801399D0 (sv)	1998-04-21	1998-04-21	Astra Pharma Prod	Method and apparatus for filling containers
GB0117583D0 (en) *	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en) *	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
US7456184B2 (en)	2003-05-01	2008-11-25	Palatin Technologies Inc.	Melanocortin receptor-specific compounds
AU2002331064B2 (en)	2001-08-10	2007-08-23	Palatin Technologies, Inc.	Peptidomimetics of biologically active metallopeptides
US7732451B2 (en)	2001-08-10	2010-06-08	Palatin Technologies, Inc.	Naphthalene-containing melanocortin receptor-specific small molecule
US7718802B2 (en)	2001-08-10	2010-05-18	Palatin Technologies, Inc.	Substituted melanocortin receptor-specific piperazine compounds
US7655658B2 (en)	2001-08-10	2010-02-02	Palatin Technologies, Inc.	Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
DE60304718T2 (de)	2002-08-06	2007-04-26	Astrazeneca Ab	Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität
US6890923B2 (en) *	2002-12-16	2005-05-10	Astrazeneca Ab	Compounds
SE0300120D0 (sv) *	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds
MXPA05007495A (es) *	2003-01-17	2005-09-21	Astrazeneca Ab	Tienopiridazinonas y su uso en la modulacion de enfermedades autoinmunes.
SE0300119D0 (sv) *	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds
CA2518398A1 (en) *	2003-03-10	2004-09-23	Schering Corporation	Heterocyclic kinase inhibitors: methods of use and synthesis
US7968548B2 (en) *	2003-05-01	2011-06-28	Palatin Technologies, Inc.	Melanocortin receptor-specific piperazine compounds with diamine groups
US7727990B2 (en)	2003-05-01	2010-06-01	Palatin Technologies, Inc.	Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7727991B2 (en)	2003-05-01	2010-06-01	Palatin Technologies, Inc.	Substituted melanocortin receptor-specific single acyl piperazine compounds
CN1925855B (zh)	2003-12-19	2010-06-16	普莱希科公司	开发Ret调节剂的化合物和方法
US7550602B1 (en) *	2004-01-14	2009-06-23	Palatin Technologies, Inc.	Small molecule compositions for sexual dysfunction
US7709484B1 (en)	2004-04-19	2010-05-04	Palatin Technologies, Inc.	Substituted melanocortin receptor-specific piperazine compounds
US7498342B2 (en)	2004-06-17	2009-03-03	Plexxikon, Inc.	Compounds modulating c-kit activity
CN101076335A (zh) *	2004-08-18	2007-11-21	默克公司	有丝分裂驱动蛋白抑制剂
US7846941B2 (en)	2005-05-17	2010-12-07	Plexxikon, Inc.	Compounds modulating c-kit and c-fms activity and uses therefor
UA95244C2 (ru)	2005-06-22	2011-07-25	Плексикон, Инк.	Соединения и способ модулирования активности киназ, и показания для их применения
US7834017B2 (en)	2006-08-11	2010-11-16	Palatin Technologies, Inc.	Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
WO2008063888A2 (en)	2006-11-22	2008-05-29	Plexxikon, Inc.	Compounds modulating c-fms and/or c-kit activity and uses therefor
RU2345996C1 (ru) *	2007-07-17	2009-02-10	Андрей Александрович Иващенко	Аннелированные азагетероциклические амиды, включающие пиримидиновый фрагмент, способ их получения и применения
WO2009012283A1 (en)	2007-07-17	2009-01-22	Plexxikon Inc.	Compounds and methods for kinase modulation, and indications therefor
RU2341527C1 (ru) *	2007-07-17	2008-12-20	Общество С Ограниченной Ответственностью "Исследовательский Институт Химического Разнообразия"	Аннелированные азагетероциклы, включающие пиримидиновый фрагмент, способ их получения и ингибиторы pi3k киназ
WO2009092566A1 (en) *	2008-01-22	2009-07-30	Boehringer Ingelheim International Gmbh	Substituted amino-benzimidazoles, medicaments comprising said compound, their use and their method of manufacture
EP2411395B1 (en) *	2009-03-23	2013-05-29	Glenmark Pharmaceuticals S.A.	Furopyrimidinedione derivatives as trpa1 modulators
MY172424A (en)	2009-04-03	2019-11-25	Hoffmann La Roche	Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
CN106220623A (zh)	2009-11-06	2016-12-14	普莱希科公司	用于激酶调节的化合物和方法及其适应症
US9624213B2 (en)	2011-02-07	2017-04-18	Plexxikon Inc.	Compounds and methods for kinase modulation, and indications therefor
AR085279A1 (es)	2011-02-21	2013-09-18	Plexxikon Inc	Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
JP5990980B2 (ja) *	2012-04-02	2016-09-14	大日本印刷株式会社	オランザピンの中間体の製造方法
US9150570B2 (en)	2012-05-31	2015-10-06	Plexxikon Inc.	Synthesis of heterocyclic compounds
AR117469A1 (es)	2018-12-21	2021-08-11	Merck Patent Gmbh	Derivados de alquino disustituidos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1999029695A1 (en)	1997-12-05	1999-06-17	Astrazeneca Uk Limited	Novel compounds
US6469014B1 (en) *	1997-05-28	2002-10-22	Astrazeneca Ab	Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
SE9702001D0 (sv)	1997-05-28	1997-05-28	Astra Pharma Prod	Novel compounds
US6232320B1 (en)	1998-06-04	2001-05-15	Abbott Laboratories	Cell adhesion-inhibiting antiinflammatory compounds
DE69912618T2 (de)	1998-08-28	2004-10-28	Astrazeneca Ab	NEUE THIENO[2,3-d]PYRIMIDINDIONE, VERFAHREN FÜR IHRE HERSTELLUNG UND IHRE VERWENDUNG IN DER THERAPIE
GB0117583D0 (en)	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en) *	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
MXPA05007495A (es)	2003-01-17	2005-09-21	Astrazeneca Ab	Tienopiridazinonas y su uso en la modulacion de enfermedades autoinmunes.
SE0300120D0 (sv) *	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds
SE0300119D0 (sv)	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds

2001
- 2001-07-28 GB GBGB0118479.5A patent/GB0118479D0/en not_active Ceased
2002
- 2002-07-24 AU AU2002319469A patent/AU2002319469B2/en not_active Ceased
- 2002-07-24 NZ NZ530495A patent/NZ530495A/en not_active IP Right Cessation
- 2002-07-24 PL PL369232A patent/PL211351B1/pl not_active IP Right Cessation
- 2002-07-24 US US10/483,162 patent/US7384950B2/en not_active Expired - Fee Related
- 2002-07-24 WO PCT/GB2002/003399 patent/WO2003011868A1/en not_active Ceased
- 2002-07-24 KR KR1020047001192A patent/KR100897469B1/ko not_active Expired - Fee Related
- 2002-07-24 MX MXPA04000677A patent/MXPA04000677A/es active IP Right Grant
- 2002-07-24 ES ES02749055T patent/ES2292784T3/es not_active Expired - Lifetime
- 2002-07-24 AT AT02749055T patent/ATE374204T1/de not_active IP Right Cessation
- 2002-07-24 HU HU0402336A patent/HUP0402336A3/hu unknown
- 2002-07-24 EP EP02749055A patent/EP1414825B9/en not_active Expired - Lifetime
- 2002-07-24 CN CNB028152506A patent/CN1324033C/zh not_active Expired - Fee Related
- 2002-07-24 RU RU2004102392/04A patent/RU2294937C9/ru not_active IP Right Cessation
- 2002-07-24 IL IL15978502A patent/IL159785A0/xx unknown
- 2002-07-24 DE DE60222671T patent/DE60222671T2/de not_active Expired - Lifetime
- 2002-07-24 BR BR0211262-0A patent/BR0211262A/pt not_active IP Right Cessation
- 2002-07-24 CA CA002453274A patent/CA2453274A1/en not_active Abandoned
- 2002-07-24 JP JP2003517059A patent/JP4456364B2/ja not_active Expired - Fee Related
- 2002-07-26 AR ARP020102842A patent/AR038000A1/es active IP Right Grant
- 2002-07-26 MY MYPI20022835A patent/MY138145A/en unknown
2004
- 2004-01-08 IL IL159785A patent/IL159785A/en not_active IP Right Cessation
- 2004-01-19 IS IS7118A patent/IS2598B/is unknown
- 2004-01-26 ZA ZA200400574A patent/ZA200400574B/en unknown
- 2004-01-27 NO NO20040364A patent/NO328713B1/no not_active IP Right Cessation
2008
- 2008-04-29 US US12/111,792 patent/US20080207642A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1414825B1 (en)	2007-09-26
HUP0402336A2 (hu)	2005-02-28
DE60222671T2 (de)	2008-06-26
RU2294937C9 (ru)	2007-07-20
WO2003011868A1 (en)	2003-02-13
CN1538970A (zh)	2004-10-20
HK1065785A1 (en)	2005-03-04
EP1414825B9 (en)	2009-09-16
US20040254198A1 (en)	2004-12-16
JP4456364B2 (ja)	2010-04-28
PL369232A1 (en)	2005-04-18
KR20040017355A (ko)	2004-02-26
IS2598B (is)	2010-03-15
IL159785A (en)	2009-11-18
EP1414825A1 (en)	2004-05-06
NO20040364L (no)	2004-03-29
BR0211262A (pt)	2004-07-20
AU2002319469B2 (en)	2007-08-09
DE60222671D1 (de)	2007-11-08
ATE374204T1 (de)	2007-10-15
ZA200400574B (en)	2005-04-26
AR038000A1 (es)	2004-12-22
NZ530495A (en)	2005-07-29
ES2292784T3 (es)	2008-03-16
AU2002319469B8 (en)	2003-02-17
PL211351B1 (pl)	2012-05-31
RU2294937C2 (ru)	2007-03-10
GB0118479D0 (en)	2001-09-19
IL159785A0 (en)	2004-06-20
HUP0402336A3 (en)	2008-09-29
JP2004538316A (ja)	2004-12-24
US7384950B2 (en)	2008-06-10
MXPA04000677A (es)	2004-04-05
CN1324033C (zh)	2007-07-04
CA2453274A1 (en)	2003-02-13
NO328713B1 (no)	2010-05-03
RU2004102392A (ru)	2005-07-10
MY138145A (en)	2009-04-30
US20080207642A1 (en)	2008-08-28
KR100897469B1 (ko)	2009-05-14

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DE60213609D1 (de)	2006-09-14	THIENOi2,3-döPYRIMIDINEDIONES ALS INHIBITOREN VON T-ZELLEN-PROLIFERATION
BRPI0406780A (pt)	2006-01-17	Novos compostos
DE60320012D1 (de)	2008-05-08	Aminoheterocyclen als vr-1 antagonisten zur behandlung von schmerzen
DK0687268T3 (da)	1998-10-12	Spiroazacykliske derivater som substans P-antagonister
EA200600358A1 (ru)	2006-08-25	Фенил- или пиридиламидные соединения в качестве антагонистов простагландина е2
CY1110240T1 (el)	2015-01-14	Νεα παραγωγα 2η-πυριδαζινο-3-ονης, φαρμακευτικες συνθεσεις που τα περιεχουν και μεθοδος για την παρασκευη του δραστικου συστατικου
MXPA05007496A (es)	2005-09-21	Tienopirimidindionas y su uso en la modulacion de enfermedades autoinmunes.
EA200600811A1 (ru)	2006-10-27	НОВЫЕ ПРОИЗВОДНЫЕ ТЕТРАГИДРОСПИРО {ПИПЕРИДИН-2,7'-ПИРРОЛО [3,2-b]ПИРИДИНА} И НОВЫЕ ПРОИЗВОДНЫЕ ИНДОЛА, ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ РАССТРОЙСТВ, СВЯЗАННЫХ С 5-HT-РЕЦЕПТОРОМ
EA200200374A1 (ru)	2002-10-31	Производные хинолилпропилпиперидина, их получение и содержащие их композиции
DE60214591D1 (en)	2006-10-19	Pyrazolpyrimidinfungizide
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SE0201659D0 (sv)	2002-05-31	Modified release pharmaceutical formulation
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DE602004009200D1 (de)	2007-11-08	Tetrahydrochinazolinderivate als cfr-antagonisten
MX2025001765A (es)	2025-05-02	Derivados deuterados de pirimidin-2-il sulfonamida
EA200100090A2 (ru)	2001-08-27	Новые пиперидин-4-сульфонамидные производные, способ их получения и содержащие их фармацевтические композиции
BRPI0415109A (pt)	2006-11-28	compostos de 1-[2-(4-hidroxifenil)-2-hidroxietil]-piperidin-4-ol como antagonistas de receptor de nmda
IL165220A0 (en)	2005-12-18	Novel compounds, their use and preparation
NO20023041D0 (no)	2002-06-21	Fremgangsmåte for fremstilling av pyrazolopyridazinderivater
DE60119383D1 (de)	2006-06-08	Farnesyltransferasehemmende 4-heterocyclylchinolin- und chinazolinderivate
DE59712632D1 (de)	2006-06-01	Verfahren zur herstellung von 3-pyrrolin-2-carbonsäure-derivaten
DE69725167D1 (de)	2003-10-30	N-benzolsulfonyl-l-prolin derivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung
ATE268771T1 (de)	2004-06-15	Verfahren zur herstellung von pyrazolopyridinderivaten
MXPA05007495A (es)	2005-09-21	Tienopiridazinonas y su uso en la modulacion de enfermedades autoinmunes.