IS7907A - Astmi og stillar ofnæmisbólgu - Google Patents
Astmi og stillar ofnæmisbólguInfo
- Publication number
- IS7907A IS7907A IS7907A IS7907A IS7907A IS 7907 A IS7907 A IS 7907A IS 7907 A IS7907 A IS 7907A IS 7907 A IS7907 A IS 7907A IS 7907 A IS7907 A IS 7907A
- Authority
- IS
- Iceland
- Prior art keywords
- asthma
- adjusts
- allergic inflammation
- allergic
- inflammation
- Prior art date
Links
- 230000009285 allergic inflammation Effects 0.000 title 1
- 208000006673 asthma Diseases 0.000 title 1
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- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
- C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
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- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
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Families Citing this family (146)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ566263A (en) | 2002-05-24 | 2009-09-25 | Millennium Pharm Inc | CCR9 inhibitors and methods of use thereof |
| US7420055B2 (en) * | 2002-11-18 | 2008-09-02 | Chemocentryx, Inc. | Aryl sulfonamides |
| KR100874292B1 (ko) | 2002-11-18 | 2008-12-18 | 케모센트릭스 | 아릴 술폰아마이드 |
| PL377314A1 (pl) | 2002-12-20 | 2006-01-23 | Amgen Inc. | Modulatory astmy i zapaleń na tle alergicznym |
| CN1511828A (zh) * | 2002-12-31 | 2004-07-14 | �й������ž�����ҽѧ��ѧԺ����ҽ | 磺酰苯胺类衍生物及其医药用途 |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| GB0307428D0 (en) * | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| US20080254053A1 (en) * | 2003-04-09 | 2008-10-16 | Mullally John P | Protocol for treatment of diabetes |
| PT1471057E (pt) | 2003-04-25 | 2006-05-31 | Actimis Pharmaceuticals Inc | Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2 |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| ATE386715T1 (de) * | 2003-11-25 | 2008-03-15 | Lilly Co Eli | Modulatoren des peroxisomproliferatoraktivierten rezeptors |
| PL1701940T3 (pl) * | 2003-12-23 | 2008-11-28 | H Lundbeck As | Pochodne 2-(1H-indolilosulfanylo)benzyloaminy jako SSRI |
| CN100584844C (zh) | 2004-01-31 | 2010-01-27 | 艾克提麦斯医药品有限公司 | 咪唑[1,2-c]嘧啶基乙酸衍生物 |
| US7714132B2 (en) | 2004-03-11 | 2010-05-11 | Actelion Pharmaceuticals, Ltd. | Tetrahydropyridoindole derivatives |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| AR052308A1 (es) * | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| UY29223A1 (es) | 2004-11-23 | 2006-06-30 | Astrazeneca Ab | Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación |
| JP2008521829A (ja) | 2004-11-30 | 2008-06-26 | プレキシコン,インコーポレーテッド | Ppar活性化合物 |
| US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
| CN101203214B (zh) | 2005-04-13 | 2012-11-21 | 艾升制药公司 | 用于治疗皮肤结缔组织疾病的β2-肾上腺素受体激动剂 |
| ZA200709817B (en) * | 2005-04-21 | 2009-02-25 | Serono Lab | 2,3 substituted pyrazine sulfonmides as inhibitors of CRTH2 |
| GB0510584D0 (en) * | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
| AR054393A1 (es) * | 2005-06-17 | 2007-06-20 | Lundbeck & Co As H | Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos. |
| US7629473B2 (en) * | 2005-06-17 | 2009-12-08 | H. Lundbeck A/S | 2-(1H-indolylsulfanyl)-aryl amine derivatives |
| WO2007014008A2 (en) * | 2005-07-22 | 2007-02-01 | Glaxo Group Limted | Benzenesulfonamide inhibitor of ccr2 chemokine receptor |
| EP1937632A1 (en) * | 2005-10-06 | 2008-07-02 | Astra Zeneca AB | Novel compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| EP1948630A2 (en) * | 2005-11-05 | 2008-07-30 | AstraZeneca AB | Novel compounds |
| GB0525141D0 (en) * | 2005-12-09 | 2006-01-18 | Novartis Ag | Organic compounds |
| TW200732296A (en) * | 2005-12-15 | 2007-09-01 | Astrazeneca Ab | Novel compounds |
| WO2007081385A2 (en) | 2006-01-11 | 2007-07-19 | Raindance Technologies, Inc. | Microfluidic devices and methods of use in the formation and control of nanoreactors |
| WO2007110876A2 (en) * | 2006-03-24 | 2007-10-04 | Panacea Biotec Ltd. | Novel sulfonanilide derivatives, pharmaceutical compositions comprising the same and process thereof |
| EP2530167A1 (en) * | 2006-05-11 | 2012-12-05 | Raindance Technologies, Inc. | Microfluidic Devices |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| AU2007256597A1 (en) * | 2006-06-09 | 2007-12-13 | Icos Corporation | Substituted phenyl acetic acids as DP-2 antagonists |
| WO2007146838A2 (en) * | 2006-06-09 | 2007-12-21 | Icos Corporation | Substituted phenyl acetic acids as dp-2 antagonists |
| US20100234364A1 (en) * | 2006-07-14 | 2010-09-16 | Arindrajit Basak | Ccr2 inhibitors and methods of use thereof |
| US8519135B2 (en) | 2006-07-14 | 2013-08-27 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2/CCR9 |
| CA2658496A1 (en) | 2006-07-22 | 2008-01-31 | Oxagen Limited | 2-{5-fluoro-2-methyl-3-[2-(phenylsulfonyl)benzyl]-1h-indol-yl} acetic acid derivatives and esters thereof having crth2 antagonist activity |
| EP2077912B1 (en) | 2006-08-07 | 2019-03-27 | The President and Fellows of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
| AU2007286829B2 (en) * | 2006-08-21 | 2013-05-02 | Array Biopharma, Inc. | 4-substituted phenoxyphenylacetic acid derivatives |
| WO2008059370A2 (en) | 2006-11-17 | 2008-05-22 | Pfizer Japan Inc. | Substituted bicyclocarboxyamide compounds |
| WO2008097559A2 (en) | 2007-02-06 | 2008-08-14 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| PE20090159A1 (es) | 2007-03-08 | 2009-02-21 | Plexxikon Inc | COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs |
| WO2008127893A1 (en) * | 2007-04-04 | 2008-10-23 | Hight H Thomas | Niacin-based pharmaceutical compositions |
| US8592221B2 (en) | 2007-04-19 | 2013-11-26 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| US7960567B2 (en) * | 2007-05-02 | 2011-06-14 | Amgen Inc. | Compounds and methods useful for treating asthma and allergic inflammation |
| UA100983C2 (ru) * | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| JP5306344B2 (ja) | 2007-07-12 | 2013-10-02 | ケモセントリックス, インコーポレイテッド | 炎症の治療のためのccr2モジュレーターとしての縮合ヘテロアリールピリジルおよびフェニルベンゼンスルホンアミド |
| BRPI0817318A2 (pt) | 2007-09-25 | 2015-03-17 | Actimis Pharmaceuticals Inc | Composto, composição farmacêutica, e, método para tratar uma doença, ou uma condição, ou sintoma da mesma. |
| JP5524847B2 (ja) | 2007-09-25 | 2014-06-18 | アクチミス ファーマシューティカルズ インコーポレーテッド | Crth2アンタゴニストとしてのアルキルチオピリミジン |
| US20100298368A1 (en) * | 2007-11-06 | 2010-11-25 | Amira Pharmaceuticals, Inc. | Antagonists of pgd2 receptors |
| WO2009061676A2 (en) * | 2007-11-06 | 2009-05-14 | Amira Pharmaceuticals, Inc. | Antagonists of pgd2 receptors |
| DK2229358T3 (da) | 2007-12-14 | 2011-07-04 | Pulmagen Therapeutics Asthma Ltd | Indoler og deres terapeutiske anvendelse |
| ES2471919T3 (es) * | 2007-12-19 | 2014-06-27 | Amgen, Inc | Derivados de ácido fenilac�tico como moduladores de inflamación |
| WO2009090399A1 (en) * | 2008-01-18 | 2009-07-23 | Argenta Discovery Limited | Indoles active on crth2 receptor |
| US7750027B2 (en) * | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| CA2712017C (en) | 2008-01-18 | 2016-08-09 | Oxagen Limited | Compounds having crth2 antagonist activity |
| JP2011509991A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Crth2アンタゴニスト活性を有する化合物 |
| EP2265581A1 (en) | 2008-01-22 | 2010-12-29 | Oxagen Limited | Compounds having crth2 antagonist activity |
| BRPI0907364A2 (pt) | 2008-02-01 | 2015-07-14 | Amira Pharmaceuticals Inc | Antagonistas aminoalquilbifenil n,n-disubstituídos de receptores d2 de prostaglandina |
| WO2009099901A1 (en) * | 2008-02-01 | 2009-08-13 | Amira Pharmaceuticals, Inc. | N,n-disubstituted aminoalkylbiphenyl antagonists of prostaglandin d2 receptors |
| WO2009102893A2 (en) | 2008-02-14 | 2009-08-20 | Amira Pharmaceuticals, Inc. | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors |
| ES2494366T3 (es) | 2008-02-22 | 2014-09-15 | Otsuka Pharmaceutical Co., Ltd. | Compuesto de benzodiacepina y composición farmacéutica |
| JP2011513242A (ja) | 2008-02-25 | 2011-04-28 | アミラ ファーマシューティカルズ,インク. | プロスタグランジンd2受容体アンタゴニスト |
| US8426449B2 (en) * | 2008-04-02 | 2013-04-23 | Panmira Pharmaceuticals, Llc | Aminoalkylphenyl antagonists of prostaglandin D2 receptors |
| WO2010008864A2 (en) | 2008-06-24 | 2010-01-21 | Amira Pharmaceuticals, Inc. | Cycloalkane[b]indole angtagonists of prostaglandin d2 receptors |
| CN103450138B (zh) | 2008-06-25 | 2015-04-08 | 阵列生物制药公司 | 制备6-取代的苯氧基色满羧酸衍生物的中间体 |
| US8071807B2 (en) | 2008-07-03 | 2011-12-06 | Panmira Pharmaceuticals, Llc | Antagonists of prostaglandin D2 receptors |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| EP4047367A1 (en) | 2008-07-18 | 2022-08-24 | Bio-Rad Laboratories, Inc. | Method for detecting target analytes with droplet libraries |
| GB2463788B (en) | 2008-09-29 | 2010-12-15 | Amira Pharmaceuticals Inc | Heteroaryl antagonists of prostaglandin D2 receptors |
| WO2010039977A2 (en) | 2008-10-01 | 2010-04-08 | Amira Pharmaceuticals, Inc. | Heteroaryl antagonists of prostaglandin d2 receptors |
| WO2010042652A2 (en) | 2008-10-08 | 2010-04-15 | Amira Pharmaceuticals, Inc. | Heteroalkyl biphenyl antagonists of prostaglandin d2 receptors |
| GB2465062B (en) | 2008-11-06 | 2011-04-13 | Amira Pharmaceuticals Inc | Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors |
| BRPI0921038A2 (pt) | 2008-11-17 | 2019-09-24 | Hoffmann La Roche | ácido naftilacéticos |
| US8383654B2 (en) | 2008-11-17 | 2013-02-26 | Panmira Pharmaceuticals, Llc | Heterocyclic antagonists of prostaglandin D2 receptors |
| CN102325767B (zh) * | 2008-12-22 | 2014-05-14 | 阵列生物制药公司 | 7-苯氧基色满羧酸衍生物 |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| WO2011002814A2 (en) * | 2009-06-30 | 2011-01-06 | Ligand Pharmaceuticals Inc. | Biaryl oxyacetic acid compounds |
| KR20120046762A (ko) * | 2009-07-31 | 2012-05-10 | 판미라 파마슈티칼스, 엘엘씨 | Dp2 수용체 길항제의 피부 제형 |
| EP2461809A4 (en) | 2009-07-31 | 2013-06-19 | Panmira Pharmaceuticals Llc | OPHTHALMIC PHARMACEUTICAL COMPOSITIONS OF DP2 RECEPTOR ANTAGONSITES |
| US8815917B2 (en) * | 2009-08-05 | 2014-08-26 | Panmira Pharmaceuticals, Llc | DP2 antagonist and uses thereof |
| TWI481601B (zh) | 2009-08-21 | 2015-04-21 | Otsuka Pharma Co Ltd | 含氮化合物及藥學組成物 |
| US8796447B2 (en) | 2009-08-21 | 2014-08-05 | Otsuka Pharmaceutical Co., Ltd. | Process for producing benzo[B][1,4]diazepine-2,4-dione compound |
| US10520500B2 (en) | 2009-10-09 | 2019-12-31 | Abdeslam El Harrak | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| JP5731538B2 (ja) | 2009-12-23 | 2015-06-10 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | Crth2モジュレーター |
| US10837883B2 (en) | 2009-12-23 | 2020-11-17 | Bio-Rad Laboratories, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
| EP2521713A4 (en) * | 2010-01-06 | 2013-10-02 | Panmira Pharmaceuticals Llc | ANTAGONIST OF DP2 AND ITS USES |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| EP4484577A3 (en) | 2010-02-12 | 2025-03-26 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| WO2011115804A1 (en) | 2010-03-17 | 2011-09-22 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EP2588465B1 (en) | 2010-06-30 | 2017-01-25 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| CN102958914B (zh) | 2010-07-05 | 2015-05-27 | 埃科特莱茵药品有限公司 | 1-苯基取代的杂环衍生物及其作为前列腺素d2受体调节剂的用途 |
| US20130259830A1 (en) | 2010-07-12 | 2013-10-03 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| WO2012009137A1 (en) | 2010-07-12 | 2012-01-19 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| US9562897B2 (en) | 2010-09-30 | 2017-02-07 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| WO2012061926A1 (en) * | 2010-11-08 | 2012-05-18 | Zalicus Pharmaceuticals Ltd. | Bisarylsulfone and dialkylarylsulfone compounds as calcium channel blockers |
| CN107266433A (zh) | 2010-11-09 | 2017-10-20 | 铁木医药有限公司 | sGC刺激剂 |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| EP3412778A1 (en) | 2011-02-11 | 2018-12-12 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| WO2012112804A1 (en) | 2011-02-18 | 2012-08-23 | Raindance Technoligies, Inc. | Compositions and methods for molecular labeling |
| EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
| EP3216872B1 (en) | 2011-06-02 | 2020-04-01 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
| EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| SG11201402796SA (en) | 2011-12-16 | 2014-06-27 | Atopix Therapeutics Ltd | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| TW201331179A (zh) | 2011-12-21 | 2013-08-01 | Actelion Pharmaceuticals Ltd | 雜環衍生物及其作為前列腺素d2受體調節劑之用途 |
| CN106117194A (zh) | 2011-12-27 | 2016-11-16 | 铁木医药有限公司 | 可用作sgc刺激剂的2‑苄基、3‑(嘧啶‑2‑基)取代的吡唑类 |
| CA2876808A1 (en) | 2012-07-05 | 2014-01-09 | Actelion Pharmaceuticals Ltd | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
| WO2014047111A1 (en) | 2012-09-18 | 2014-03-27 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EP2897953B8 (en) | 2012-09-19 | 2019-06-26 | Cyclerion Therapeutics, Inc. | Sgc stimulators |
| EA033168B1 (ru) | 2013-03-15 | 2019-09-30 | Сайклерион Терапьютикс, Инк. | СТИМУЛЯТОРЫ sGC |
| CN104341307B (zh) * | 2013-08-05 | 2016-12-28 | 北京京朋汇药业研究发展有限公司 | 苯乙酸衍生物及其抗肿瘤用途 |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| CA2933250A1 (en) | 2013-12-11 | 2015-06-18 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| GB201322273D0 (en) | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
| WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
| EP3094327A1 (en) | 2014-01-13 | 2016-11-23 | Ironwood Pharmaceuticals, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS |
| GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| EP3194386A2 (en) | 2014-09-17 | 2017-07-26 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EP3194382B1 (en) | 2014-09-17 | 2021-09-08 | Cyclerion Therapeutics, Inc. | Pyrazole derivatives as sgc stimulators |
| US20170298055A1 (en) | 2014-09-17 | 2017-10-19 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| JP6770522B2 (ja) | 2015-02-13 | 2020-10-14 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 全身性エリテマトーデスを予防し、及び/又は、治療するためのptgdr−1及び/又はptgdr−2アンタゴニスト |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
| EA039683B1 (ru) | 2016-07-07 | 2022-02-28 | Сайклерион Терапьютикс, Инк. | ФОСФОРСОДЕРЖАЩИЕ ПРОЛЕКАРСТВА СТИМУЛЯТОРОВ sGC |
| CN109563087A (zh) | 2016-07-07 | 2019-04-02 | 铁木医药有限公司 | sGC刺激剂的固体形式 |
| RU2765737C2 (ru) | 2016-11-23 | 2022-02-02 | Хемоцентрикс, Инк. | Способ лечения фокально-сегментарного гломерулосклероза |
| RU2020113612A (ru) | 2017-10-11 | 2021-11-12 | Хемоцентрикс, Инк. | Лечение фокально-сегментарного гломерулосклероза антагонистами ccr2 |
| MX2021012105A (es) | 2019-04-03 | 2021-11-03 | Aligos Therapeutics Inc | Compuestos de pirrol. |
| CN112500281A (zh) * | 2020-12-07 | 2021-03-16 | 唐山师范学院 | 丁香酸的制备方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8704158D0 (en) | 1987-02-23 | 1987-04-01 | Wellcome Found | Substituted hydantoin compounds |
| DE4041780A1 (de) * | 1990-12-24 | 1992-06-25 | Boehringer Mannheim Gmbh | Neue amine, verfahren zu ihrer herstellung, sowie diese verbindungen enthaltende arzneimittel |
| JP3894949B2 (ja) | 1993-06-30 | 2007-03-22 | ザ、ウェルカム、ファンデーション、リミテッド | 抗アテローム性動脈硬化症ジアリール化合物 |
| US5545669A (en) * | 1994-06-02 | 1996-08-13 | Adams; Jerry L. | Anti-inflammatory compounds |
| GB9420557D0 (en) * | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
| ES2180664T3 (es) | 1994-12-20 | 2003-02-16 | Hoffmann La Roche | Derivados de aril- y heteroarilsulfonamida, obtencion y uso de los mismos en calidad de antagonistas de endotelina. |
| EP0929547B1 (en) | 1996-09-12 | 2002-11-27 | Schering Aktiengesellschaft | Benzamidine derivatives substituted by cyclic amino acid or cycl ic hydroxy acid derivatives and their use as anti-coagulants |
| US6008234A (en) | 1996-09-12 | 1999-12-28 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants |
| TW523506B (en) | 1996-12-18 | 2003-03-11 | Ono Pharmaceutical Co | Sulfonamide or carbamide derivatives and drugs containing the same as active ingredients |
| JPH11202458A (ja) | 1998-01-16 | 1999-07-30 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
| WO1999055663A1 (en) | 1998-04-29 | 1999-11-04 | Vertex Pharmaceuticals Incorporated | Inhibitors of impdh enzyme |
| JP2000007646A (ja) * | 1998-06-16 | 2000-01-11 | Ono Pharmaceut Co Ltd | スルフォンアミド誘導体およびそれらを有効成分と して含有する薬剤 |
| AR023659A1 (es) | 1998-09-18 | 2002-09-04 | Vertex Pharma | Un compuesto inhibidor de p38, una composicion farmaceutica que lo comprende y el uso de dicha composicion en el tratamiento y prevencion de estados patologicos |
| US6248739B1 (en) | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | Quinolinecarboxamides as antiviral agents |
| EP1176139B1 (en) | 1999-03-10 | 2005-05-18 | Shionogi & Co., Ltd. | Medicinal compositions with 2.2.1] and 3.1.1] bicycloskeleton antagonistic to both of pgd 2?/txa 2? receptors |
| WO2001014882A1 (fr) | 1999-08-23 | 2001-03-01 | Bml, Inc. | Identification des proprietes d'une substance pour les recepteurs de prostaglandine d |
| US6531291B1 (en) | 1999-11-10 | 2003-03-11 | The Trustees Of Columbia University In The City Of New York | Antimicrobial activity of gemfibrozil and related compounds and derivatives and metabolites thereof |
| US20010047027A1 (en) | 2000-04-12 | 2001-11-29 | Marc Labelle | Prostaglandin D2 receptor antagonists |
| JPWO2001094309A1 (ja) | 2000-06-02 | 2004-02-05 | 塩野義製薬株式会社 | Pgd2/txa2両受容体拮抗性医薬組成物 |
| US6878522B2 (en) | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
| AU2002229611A1 (en) | 2000-12-08 | 2002-06-18 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of active compounds capable of modulating the intracellular pathway triggered by the dp receptor in langerhans cells |
| AU2002302248B2 (en) | 2001-05-23 | 2008-03-06 | Merck Frosst Canada Ltd. | Dihydropyrrolo[1,2-A]indole and tetrahydropyrido[1,2-A]-indole derivatives as prostaglandin D2 receptor antagonists |
| CN101284773A (zh) * | 2001-08-09 | 2008-10-15 | 小野药品工业株式会社 | 羧酸衍生物及以它为活性成分的药剂 |
| SE0200356D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| MXPA04009095A (es) | 2002-03-19 | 2004-12-06 | Ono Pharmaceutical Co | Compuesto de acido carboxilico y agente farmaceutico que comprende el compuesto como ingrediente activo. |
| AU2003231509A1 (en) | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Compound exhibiting pgd 2 receptor antagonism |
| WO2003097042A1 (en) | 2002-05-16 | 2003-11-27 | Shionogi & Co., Ltd. | Pgd2 receptor antagonist |
| GB2388540A (en) | 2002-05-17 | 2003-11-19 | Bayer Ag | New use of Ramatroban |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| PL377314A1 (pl) | 2002-12-20 | 2006-01-23 | Amgen Inc. | Modulatory astmy i zapaleń na tle alergicznym |
-
2003
- 2003-12-19 PL PL377314A patent/PL377314A1/pl not_active Application Discontinuation
- 2003-12-19 KR KR1020057011677A patent/KR20050111314A/ko not_active Abandoned
- 2003-12-19 ES ES03814219T patent/ES2401079T3/es not_active Expired - Lifetime
- 2003-12-19 EA EA200501017A patent/EA011087B1/ru not_active IP Right Cessation
- 2003-12-19 JP JP2004563827A patent/JP4457017B2/ja not_active Expired - Fee Related
- 2003-12-19 ZA ZA200505523A patent/ZA200505523B/en unknown
- 2003-12-19 NZ NZ541234A patent/NZ541234A/en not_active IP Right Cessation
- 2003-12-19 AU AU2003297398A patent/AU2003297398B2/en not_active Ceased
- 2003-12-19 EP EP03814219A patent/EP1585511B1/en not_active Expired - Lifetime
- 2003-12-19 MX MXPA05006701A patent/MXPA05006701A/es active IP Right Grant
- 2003-12-19 US US10/742,281 patent/US7321001B2/en not_active Expired - Lifetime
- 2003-12-19 CN CNB2003801097235A patent/CN100406007C/zh not_active Expired - Fee Related
- 2003-12-19 WO PCT/US2003/040617 patent/WO2004058164A2/en not_active Ceased
- 2003-12-19 BR BR0317591-0A patent/BR0317591A/pt not_active IP Right Cessation
- 2003-12-19 CA CA2511214A patent/CA2511214C/en not_active Expired - Fee Related
-
2005
- 2005-06-22 IS IS7907A patent/IS7907A/is unknown
- 2005-06-24 NO NO20053114A patent/NO20053114L/no not_active Application Discontinuation
-
2007
- 2007-11-26 US US11/986,863 patent/US7541383B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20080085891A1 (en) | 2008-04-10 |
| NO20053114L (no) | 2005-09-19 |
| CN1767823A (zh) | 2006-05-03 |
| ZA200505523B (en) | 2006-09-27 |
| JP2006516143A (ja) | 2006-06-22 |
| KR20050111314A (ko) | 2005-11-24 |
| NO20053114D0 (no) | 2005-06-24 |
| MXPA05006701A (es) | 2006-03-30 |
| EP1585511A4 (en) | 2007-08-29 |
| ES2401079T3 (es) | 2013-04-16 |
| US20040220237A1 (en) | 2004-11-04 |
| JP4457017B2 (ja) | 2010-04-28 |
| PL377314A1 (pl) | 2006-01-23 |
| NZ541234A (en) | 2008-06-30 |
| WO2004058164A2 (en) | 2004-07-15 |
| WO2004058164A3 (en) | 2004-08-26 |
| AU2003297398B2 (en) | 2009-09-24 |
| EA011087B1 (ru) | 2008-12-30 |
| US7541383B2 (en) | 2009-06-02 |
| EP1585511B1 (en) | 2013-01-23 |
| CA2511214C (en) | 2012-12-18 |
| BR0317591A (pt) | 2005-11-22 |
| EP1585511A2 (en) | 2005-10-19 |
| CA2511214A1 (en) | 2004-07-15 |
| AU2003297398A1 (en) | 2004-07-22 |
| CN100406007C (zh) | 2008-07-30 |
| US7321001B2 (en) | 2008-01-22 |
| EA200501017A1 (ru) | 2006-02-24 |
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