IS7963A - Efnasambönd með hamlandi virkni gegn prólýlólígópeptíðasa - Google Patents
Efnasambönd með hamlandi virkni gegn prólýlólígópeptíðasaInfo
- Publication number
- IS7963A IS7963A IS7963A IS7963A IS7963A IS 7963 A IS7963 A IS 7963A IS 7963 A IS7963 A IS 7963A IS 7963 A IS7963 A IS 7963A IS 7963 A IS7963 A IS 7963A
- Authority
- IS
- Iceland
- Prior art keywords
- prolyloligopeptidase
- inhibitors
- compounds
- Prior art date
Links
- 101001095266 Homo sapiens Prolyl endopeptidase Proteins 0.000 title 1
- 102000056251 Prolyl Oligopeptidases Human genes 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20030014A FI20030014A0 (fi) | 2003-01-03 | 2003-01-03 | Prolyylioligopeptidaasia inhiboivaa aktiivisuutta omaavia yhdisteitä |
| PCT/FI2004/000001 WO2004060862A2 (en) | 2003-01-03 | 2004-01-02 | Compounds having prolyl oligopeptidase inhibitory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7963A true IS7963A (is) | 2005-07-28 |
Family
ID=8565256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7963A IS7963A (is) | 2003-01-03 | 2005-07-28 | Efnasambönd með hamlandi virkni gegn prólýlólígópeptíðasa |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060229254A1 (is) |
| EP (1) | EP1581489A2 (is) |
| JP (1) | JP2006516557A (is) |
| KR (1) | KR20060027789A (is) |
| CN (1) | CN1747930A (is) |
| AU (1) | AU2004203788A1 (is) |
| BR (1) | BRPI0406618A (is) |
| CA (1) | CA2511856A1 (is) |
| EA (1) | EA010022B1 (is) |
| FI (1) | FI20030014A0 (is) |
| HR (1) | HRP20050693A2 (is) |
| IS (1) | IS7963A (is) |
| MX (1) | MXPA05007262A (is) |
| NO (1) | NO20053726L (is) |
| PL (1) | PL378329A1 (is) |
| RS (1) | RS20050514A (is) |
| WO (1) | WO2004060862A2 (is) |
| ZA (1) | ZA200505183B (is) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT201800004T1 (it) | 2009-12-18 | 2018-03-08 | Ogeda Sa | Derivati di acido pirrolidin carbossilico come agonisti del recettore accoppiato a proteina g 43 (gpr43), composizione farmaceutica e metodi per l'uso nel trattamento di disturbi metabolici |
| EP2730571A1 (en) | 2012-11-12 | 2014-05-14 | Universitat De Barcelona | 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives |
| CA2929436C (en) | 2013-11-27 | 2021-06-15 | Euroscreen Sa | Compounds, pharmaceutical composition and methods for use in treating inflammatory diseases |
| KR101913506B1 (ko) * | 2017-07-18 | 2018-10-30 | 경상대학교산학협력단 | 프롤릴 올리고펩티다아제 억제제를 유효성분으로 함유하는 퇴행성 뇌질환 예방 또는 치료용 조성물 |
| HRP20241527T1 (hr) | 2020-07-07 | 2025-01-03 | Accure Therapeutics, S.L. | 1-[1-(4-benziloksi-3,5-difluorbenzoil)-4-fluorpirolidin-2-karbonil]pirolidin-2-karbonitril |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4483991A (en) * | 1983-01-17 | 1984-11-20 | American Home Products Corporation | Hypotensive agents |
| DE3680578D1 (de) * | 1985-04-16 | 1991-09-05 | Suntory Ltd | Dipeptid-derivate, verfahren zur herstellung, pharmazeutische zusammensetzungen und ihre anwendung. |
| CA1320734C (en) * | 1986-02-04 | 1993-07-27 | Suntory Limited | Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same |
| JPH0696563B2 (ja) * | 1986-02-04 | 1994-11-30 | サントリー株式会社 | アシルアミノ酸誘導体、その製法並びに用途 |
| FI925500A7 (fi) * | 1990-06-04 | 1992-12-03 | Pfizer | Aromaattisia pyrrolidiini- ja tiatsolidiiniamideja |
| CA2084204A1 (en) * | 1990-06-07 | 1991-12-08 | Akihiro Okubo | Arylalkanoylamine derivative and drug containing the same |
| SI0915088T1 (en) * | 1997-10-31 | 2002-12-31 | F. Hoffmann-La Roche Ag | D-proline derivatives |
-
2003
- 2003-01-03 FI FI20030014A patent/FI20030014A0/fi unknown
-
2004
- 2004-01-02 EP EP04700047A patent/EP1581489A2/en not_active Withdrawn
- 2004-01-02 JP JP2006500146A patent/JP2006516557A/ja active Pending
- 2004-01-02 US US10/541,387 patent/US20060229254A1/en not_active Abandoned
- 2004-01-02 EA EA200501083A patent/EA010022B1/ru not_active IP Right Cessation
- 2004-01-02 CA CA002511856A patent/CA2511856A1/en not_active Abandoned
- 2004-01-02 KR KR1020057012201A patent/KR20060027789A/ko not_active Withdrawn
- 2004-01-02 CN CNA2004800034680A patent/CN1747930A/zh active Pending
- 2004-01-02 AU AU2004203788A patent/AU2004203788A1/en not_active Abandoned
- 2004-01-02 RS YUP-2005/0514A patent/RS20050514A/sr unknown
- 2004-01-02 WO PCT/FI2004/000001 patent/WO2004060862A2/en not_active Ceased
- 2004-01-02 HR HR20050693A patent/HRP20050693A2/hr not_active Application Discontinuation
- 2004-01-02 MX MXPA05007262A patent/MXPA05007262A/es not_active Application Discontinuation
- 2004-01-02 PL PL378329A patent/PL378329A1/pl unknown
- 2004-01-02 BR BR0406618-9A patent/BRPI0406618A/pt not_active IP Right Cessation
-
2005
- 2005-06-27 ZA ZA200505183A patent/ZA200505183B/en unknown
- 2005-07-28 IS IS7963A patent/IS7963A/is unknown
- 2005-08-03 NO NO20053726A patent/NO20053726L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006516557A (ja) | 2006-07-06 |
| PL378329A1 (pl) | 2006-03-20 |
| EP1581489A2 (en) | 2005-10-05 |
| AU2004203788A1 (en) | 2004-07-22 |
| KR20060027789A (ko) | 2006-03-28 |
| EA200501083A1 (ru) | 2006-02-24 |
| NO20053726D0 (no) | 2005-08-03 |
| WO2004060862A2 (en) | 2004-07-22 |
| HRP20050693A2 (en) | 2005-10-31 |
| FI20030014A0 (fi) | 2003-01-03 |
| WO2004060862A3 (en) | 2004-11-25 |
| ZA200505183B (en) | 2006-04-26 |
| BRPI0406618A (pt) | 2005-12-06 |
| EA010022B1 (ru) | 2008-06-30 |
| CA2511856A1 (en) | 2004-07-22 |
| NO20053726L (no) | 2005-09-28 |
| MXPA05007262A (es) | 2005-09-08 |
| US20060229254A1 (en) | 2006-10-12 |
| CN1747930A (zh) | 2006-03-15 |
| RS20050514A (sr) | 2007-12-31 |
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