IS7965A - Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi - Google Patents

Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi

Info

Publication number: IS7965A
Authority: IS; Iceland
Prior art keywords: thienopyrimidinedione; sup; self; development; hypersensitivity disease
Prior art date: 2003-01-17

Application number

IS7965A

Other languages

English (en)

Other versions

IS2376B (is

Inventor

David Guile Simon

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-17

Filing date

2005-07-29

Publication date

2005-07-29

2005-07-29 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2005-07-29 Publication of IS7965A publication Critical patent/IS7965A/is

2008-07-15 Publication of IS2376B publication Critical patent/IS2376B/is

Links

QAFVXBQPQCSSLI-UHFFFAOYSA-N 1h-thieno[3,2-d]pyrimidine-2,4-dione Chemical compound O=C1NC(=O)NC2=C1SC=C2 QAFVXBQPQCSSLI-UHFFFAOYSA-N 0.000 title 1
206010020751 Hypersensitivity Diseases 0.000 title 1
208000026935 allergic disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
238000002560 therapeutic procedure Methods 0.000 abstract 2
206010062016 Immunosuppression Diseases 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IS7965A 2003-01-17 2005-07-29 Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi IS2376B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0300119A SE0300119D0 (sv)	2003-01-17	2003-01-17	Novel compounds
PCT/SE2004/000052 WO2004065394A1 (en)	2003-01-17	2004-01-15	Thienopyrimidinediones and their use in the modulation of autoimmune disease

Publications (2)

Publication Number	Publication Date
IS7965A true IS7965A (is)	2005-07-29
IS2376B IS2376B (is)	2008-07-15

Family

ID=20290154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7965A IS2376B (is)	2003-01-17	2005-07-29	Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi

Country Status (23)

Country	Link
US (2)	US7384951B2 (is)
EP (1)	EP1587812B1 (is)
JP (1)	JP4519121B2 (is)
KR (2)	KR101107486B1 (is)
CN (1)	CN100334093C (is)
AT (1)	ATE335748T1 (is)
AU (1)	AU2004206012B2 (is)
BR (1)	BRPI0406801B8 (is)
CA (1)	CA2512441C (is)
DE (1)	DE602004001857T2 (is)
EG (1)	EG25613A (is)
ES (1)	ES2270337T3 (is)
IL (1)	IL169370A (is)
IS (1)	IS2376B (is)
MX (1)	MXPA05007496A (is)
NO (1)	NO333702B1 (is)
NZ (1)	NZ541217A (is)
PL (1)	PL214682B1 (is)
RU (1)	RU2331647C2 (is)
SE (1)	SE0300119D0 (is)
UA (1)	UA81788C2 (is)
WO (1)	WO2004065394A1 (is)
ZA (1)	ZA200505364B (is)

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GB0117583D0 (en) *	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en) *	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
SE0300120D0 (sv) *	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds
PL378221A1 (pl) *	2003-01-17	2006-03-20	Astrazeneca Ab	Tienopirydazynony i ich zastosowanie w modulacji choroby autoimmunologicznej
CN1925855B (zh)	2003-12-19	2010-06-16	普莱希科公司	开发Ret调节剂的化合物和方法
US7498342B2 (en)	2004-06-17	2009-03-03	Plexxikon, Inc.	Compounds modulating c-kit activity
MX2007014377A (es)	2005-05-17	2008-02-06	Plexxikon Inc	Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina.
PL2395004T3 (pl)	2005-06-22	2016-08-31	Plexxikon Inc	Pochodne pirolo[2,3-b]pirydyny jako inhibitory kinazy białkowej
WO2008063888A2 (en)	2006-11-22	2008-05-29	Plexxikon, Inc.	Compounds modulating c-fms and/or c-kit activity and uses therefor
US7872018B2 (en)	2006-12-21	2011-01-18	Plexxikon, Inc.	Compounds and methods for kinase modulation, and indications therefor
WO2008079909A1 (en)	2006-12-21	2008-07-03	Plexxikon, Inc.	Pyrrolo [2,3-b] pyridines as kinase modulators
PE20081581A1 (es)	2006-12-21	2008-11-12	Plexxikon Inc	COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA
GB0713479D0 (en) *	2007-07-11	2007-08-22	Syngenta Participations Ag	Substituted aromatic heterocyclic compounds as fungicides
MX2010000617A (es)	2007-07-17	2010-05-17	Plexxikon Inc	Compuestos y metodos para modulacion de cinasa, e indicaciones de estos.
WO2010089580A1 (en)	2009-02-06	2010-08-12	Astrazeneca Ab	Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
EP2411395B1 (en) *	2009-03-23	2013-05-29	Glenmark Pharmaceuticals S.A.	Furopyrimidinedione derivatives as trpa1 modulators
DK2411397T3 (da) *	2009-03-23	2013-08-05	Glenmark Pharmaceuticals Sa	Isothiazol-pyrimidindionderivater som modulatorer af TRPA1
EA031116B1 (ru)	2009-04-03	2018-11-30	Ф. Хоффманн-Ля Рош Аг	КРИСТАЛЛИЧЕСКИЕ ПОЛИМОРФНЫЕ ФОРМЫ {3-[5-(4-ХЛОРФЕНИЛ)-1H-ПИРРОЛО[2,3-b]ПИРИДИН-3-КАРБОНИЛ]-2,4-ДИФТОРФЕНИЛ}АМИДА ПРОПАН-1-СУЛЬФОНОВОЙ КИСЛОТЫ
US8329724B2 (en)	2009-08-03	2012-12-11	Hoffmann-La Roche Inc.	Process for the manufacture of pharmaceutically active compounds
UA105813C2 (uk)	2009-11-06	2014-06-25	Плексікон, Інк.	Сполуки-інгібітори кіназ та фармацевтична композиція (варіанти)
PL2672967T3 (pl)	2011-02-07	2019-04-30	Plexxikon Inc	Związki i sposoby modulacji kinaz i wskazania ku temu
TWI558702B (zh)	2011-02-21	2016-11-21	普雷辛肯公司	醫藥活性物質的固態形式
WO2013109972A2 (en)	2012-01-20	2013-07-25	Regents Of The University Of Minnesota	Therapeutic compounds
GB2523211B (en)	2012-01-27	2020-03-18	Univ Jefferson	MCT protein inhibitor-related prognostic and therapeutic methods
US9150570B2 (en)	2012-05-31	2015-10-06	Plexxikon Inc.	Synthesis of heterocyclic compounds
WO2014172627A1 (en)	2013-04-19	2014-10-23	Thomas Jefferson University	Caveolin-1 related methods for treating glioblastoma with temozolomide
KR102228034B1 (ko) *	2013-10-21	2021-03-16	제노스코	치환된 피리미딘 화합물 및 syk 억제제로서의 이의 용도
EP3247360B1 (en)	2015-01-22	2021-08-25	The Scripps Research Institute	Heterocyclic inhibitors of monocarboxylate transporters
UY36586A (es) *	2015-03-26	2016-10-31	Bayer Pharma AG	Heterociclilmetiltienouracilos y uso de los mismos
KR101712838B1 (ko) *	2016-03-17	2017-03-07	주식회사 골프존	가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101712836B1 (ko) *	2016-03-17	2017-03-22	주식회사 골프존	가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101730536B1 (ko) *	2016-03-17	2017-05-02	주식회사 골프존	스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체
TWI823932B (zh)	2018-05-11	2023-12-01	中國大陸商迪哲（江蘇）醫藥有限公司	三唑并嘧啶化合物及其在治療癌症中之用途
CN119080799B (zh) *	2024-09-27	2025-12-05	山东大学	一种n-羟基噻吩并嘧啶二酮类衍生物及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US738495A (en) *	1902-12-26	1903-09-08	William E Sherwood	Thill-coupling.
WO1999029695A1 (en)	1997-12-05	1999-06-17	Astrazeneca Uk Limited	Novel compounds
US6469014B1 (en) *	1997-05-28	2002-10-22	Astrazeneca Ab	Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
SE9702001D0 (sv)	1997-05-28	1997-05-28	Astra Pharma Prod	Novel compounds
US6232320B1 (en)	1998-06-04	2001-05-15	Abbott Laboratories	Cell adhesion-inhibiting antiinflammatory compounds
PT1107973E (pt)	1998-08-28	2004-03-31	Astrazeneca Ab	Novas tieno¬2,3-d\| pirimidinodionas processo para a sua preparacao e sua utilizacao em terapia
AU2001252825A1 (en) *	2000-05-04	2001-11-12	Astrazeneca Ab	Thieno(2,3-d)pyrimidinediones and their use as pharmaceuticals
GB0117583D0 (en) *	2001-07-19	2001-09-12	Astrazeneca Ab	Novel compounds
GB0118479D0 (en)	2001-07-28	2001-09-19	Astrazeneca Ab	Novel compounds
PL378221A1 (pl) *	2003-01-17	2006-03-20	Astrazeneca Ab	Tienopirydazynony i ich zastosowanie w modulacji choroby autoimmunologicznej
SE0300120D0 (sv) *	2003-01-17	2003-01-17	Astrazeneca Ab	Novel compounds

2003
- 2003-01-17 SE SE0300119A patent/SE0300119D0/xx unknown
2004
- 2004-01-15 BR BRPI0406801A patent/BRPI0406801B8/pt not_active IP Right Cessation
- 2004-01-15 UA UAA200506377A patent/UA81788C2/uk unknown
- 2004-01-15 JP JP2006500750A patent/JP4519121B2/ja not_active Expired - Fee Related
- 2004-01-15 CA CA2512441A patent/CA2512441C/en not_active Expired - Lifetime
- 2004-01-15 AU AU2004206012A patent/AU2004206012B2/en not_active Ceased
- 2004-01-15 PL PL378222A patent/PL214682B1/pl unknown
- 2004-01-15 WO PCT/SE2004/000052 patent/WO2004065394A1/en not_active Ceased
- 2004-01-15 US US10/542,197 patent/US7384951B2/en not_active Expired - Lifetime
- 2004-01-15 EP EP04702477A patent/EP1587812B1/en not_active Expired - Lifetime
- 2004-01-15 NZ NZ541217A patent/NZ541217A/en not_active IP Right Cessation
- 2004-01-15 CN CNB2004800071073A patent/CN100334093C/zh not_active Expired - Fee Related
- 2004-01-15 KR KR1020057013126A patent/KR101107486B1/ko not_active Expired - Fee Related
- 2004-01-15 RU RU2005121494/04A patent/RU2331647C2/ru not_active IP Right Cessation
- 2004-01-15 KR KR1020117022785A patent/KR20110125256A/ko not_active Withdrawn
- 2004-01-15 DE DE602004001857T patent/DE602004001857T2/de not_active Expired - Lifetime
- 2004-01-15 AT AT04702477T patent/ATE335748T1/de not_active IP Right Cessation
- 2004-01-15 ES ES04702477T patent/ES2270337T3/es not_active Expired - Lifetime
- 2004-01-15 MX MXPA05007496A patent/MXPA05007496A/es active IP Right Grant
2005
- 2005-06-23 IL IL169370A patent/IL169370A/en active IP Right Grant
- 2005-07-01 ZA ZA2005/05364A patent/ZA200505364B/en unknown
- 2005-07-12 EG EGNA2005000380 patent/EG25613A/xx active
- 2005-07-29 IS IS7965A patent/IS2376B/is unknown
- 2005-08-15 NO NO20053826A patent/NO333702B1/no not_active IP Right Cessation
2008
- 2008-05-05 US US12/115,171 patent/US20080214579A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EG25613A (en)	2012-03-22
CA2512441C (en)	2012-01-03
CA2512441A1 (en)	2004-08-05
KR20050092760A (ko)	2005-09-22
NO20053826L (no)	2005-10-17
US7384951B2 (en)	2008-06-10
JP4519121B2 (ja)	2010-08-04
US20080214579A1 (en)	2008-09-04
MXPA05007496A (es)	2005-09-21
SE0300119D0 (sv)	2003-01-17
US20060052400A1 (en)	2006-03-09
IL169370A0 (en)	2007-07-04
JP2006516974A (ja)	2006-07-13
BRPI0406801B8 (pt)	2021-05-25
KR101107486B1 (ko)	2012-01-19
CN100334093C (zh)	2007-08-29
NZ541217A (en)	2008-05-30
RU2005121494A (ru)	2006-02-10
AU2004206012A1 (en)	2004-08-05
HK1081959A1 (en)	2006-05-26
EP1587812B1 (en)	2006-08-09
ATE335748T1 (de)	2006-09-15
DE602004001857T2 (de)	2007-05-24
BRPI0406801A (pt)	2006-01-17
PL214682B1 (pl)	2013-09-30
WO2004065394A1 (en)	2004-08-05
CN1761672A (zh)	2006-04-19
EP1587812A1 (en)	2005-10-26
NO20053826D0 (no)	2005-08-15
NO333702B1 (no)	2013-08-26
RU2331647C2 (ru)	2008-08-20
IS2376B (is)	2008-07-15
DE602004001857D1 (de)	2006-09-21
PL378222A1 (pl)	2006-03-20
UA81788C2 (uk)	2008-02-11
ZA200505364B (en)	2006-09-27
KR20110125256A (ko)	2011-11-18
ES2270337T3 (es)	2007-04-01
IL169370A (en)	2011-05-31
BRPI0406801B1 (pt)	2018-04-03
AU2004206012B2 (en)	2007-06-14

Publication	Publication Date	Title
IS2376B (is)	2008-07-15	Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi
SE0301700D0 (sv)	2003-06-10	Novel compounds
NO20070224L (no)	2007-04-02	2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
SE0200920D0 (sv)	2002-03-25	Novel compounds
PT1263725E (pt)	2005-02-28	Novos compostos
IS6658A (is)	2002-12-17	Ný efnasambönd
SE0302139D0 (sv)	2003-07-28	Novel compounds
TW200613243A (en)	2006-05-01	Novel compounds
UA84208C2 (en)	2008-09-25	Tetraazabenzo(e)azulene derivatives and analogs thereof
SE0300480D0 (sv)	2003-02-21	Novel compounds
WO2003086306A3 (en)	2004-02-19	5ht2c receptor modulators
GB0112348D0 (en)	2001-07-11	Compounds
EA200401526A1 (ru)	2005-04-28	Новые соединения и их применение
SE0401762D0 (sv)	2004-07-05	Novel compounds
DK1517890T3 (da)	2008-11-10	Kationisk substituerede diphenylazetidinoner, fremgangsmåde til deres fremstilling, lægemidler indeholdende disse forbindelser og deres anvendelse
TW200604197A (en)	2006-02-01	New compounds
SE0402925D0 (sv)	2004-11-30	Novel Compounds
SE0101038D0 (sv)	2001-03-23	Novel compounds
SE0303280D0 (sv)	2003-12-05	Novel compounds
SE0401763D0 (sv)	2004-07-05	Compounds
EA200600992A1 (ru)	2006-10-27	Амиды тиазолидинона, амиды тиазолидинкарбоновой кислоты, способы их получения и их применение
DK1727817T3 (da)	2011-01-10	Azabicyclooctan-3-onderivativer og anvendelse heraf
SE0302755D0 (sv)	2003-10-17	Novel compounds
SE0202693D0 (sv)	2002-09-11	Compounds
SE0202692D0 (sv)	2002-09-11	Compounds