IS8086A - Lyfjadreifinga kerfi - Google Patents

Lyfjadreifinga kerfi

Info

Publication number
IS8086A
IS8086A IS8086A IS8086A IS8086A IS 8086 A IS8086 A IS 8086A IS 8086 A IS8086 A IS 8086A IS 8086 A IS8086 A IS 8086A IS 8086 A IS8086 A IS 8086A
Authority
IS
Iceland
Prior art keywords
loaded
intermediate layer
thermoplastic polymer
drug
distribution system
Prior art date
Application number
IS8086A
Other languages
English (en)
Other versions
IS2864B (is
Inventor
Johannes Joseph Groenewegen Rudolf
De Graaff Wouter
Jan Out Henk
Original Assignee
Akzo Novel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36701594&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8086(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Novel N.V. filed Critical Akzo Novel N.V.
Publication of IS8086A publication Critical patent/IS8086A/is
Publication of IS2864B publication Critical patent/IS2864B/is

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Nanotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IS8086A 2003-05-23 2005-10-24 Lyfjadreifingakerfi IS2864B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47305503P 2003-05-23 2003-05-23
EP03101490 2003-05-23
PCT/EP2004/050850 WO2004103336A2 (en) 2003-05-23 2004-05-19 Drug delivery system

Publications (2)

Publication Number Publication Date
IS8086A true IS8086A (is) 2005-10-24
IS2864B IS2864B (is) 2014-01-15

Family

ID=36701594

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8086A IS2864B (is) 2003-05-23 2005-10-24 Lyfjadreifingakerfi

Country Status (29)

Country Link
US (3) US8333983B2 (is)
EP (1) EP1631255B1 (is)
JP (1) JP4685780B2 (is)
KR (1) KR101116267B1 (is)
CN (1) CN1794974B (is)
AR (1) AR044547A1 (is)
AU (1) AU2004241747B2 (is)
BR (1) BRPI0410455B8 (is)
CA (1) CA2524665C (is)
CO (1) CO5630021A2 (is)
CY (1) CY1113500T1 (is)
DK (1) DK1631255T3 (is)
EC (1) ECSP056250A (is)
ES (1) ES2396100T3 (is)
HR (1) HRP20050945B1 (is)
IL (1) IL171622A (is)
IS (1) IS2864B (is)
MX (1) MXPA05012595A (is)
NO (1) NO336456B1 (is)
NZ (1) NZ543652A (is)
PE (1) PE20050815A1 (is)
PL (1) PL1631255T3 (is)
PT (1) PT1631255E (is)
RU (1) RU2340344C2 (is)
SI (1) SI1631255T1 (is)
TW (1) TWI336627B (is)
UA (1) UA84287C2 (is)
WO (1) WO2004103336A2 (is)
ZA (1) ZA200509450B (is)

Families Citing this family (47)

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US8703167B2 (en) * 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
US20100136090A1 (en) * 2006-11-20 2010-06-03 N.V. Organon; Intervet International B.V. Helically-Shaped Drug Delivery System
CA2669833A1 (en) * 2006-11-22 2008-05-29 N.V. Organon Vaginal delivery system for mirtazapine
AR066166A1 (es) * 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
EP2062568A1 (en) * 2007-11-22 2009-05-27 Bayer Schering Pharma Oy Vaginal delivery system
WO2009141309A1 (en) * 2008-05-20 2009-11-26 N.V. Organon Delivery system for paliperidone
ES2344673B1 (es) * 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
WO2010077096A2 (ko) * 2008-12-31 2010-07-08 한올바이오파마주식회사 약물전달기구
BRPI1009586A2 (pt) 2009-03-17 2016-03-08 Intervet Int Bv sistema de administração de medicamento zootécnico, e, método para aprimorar o crescimento e ganho de peso em animais de criação
AU2010274946B2 (en) * 2009-07-21 2013-09-12 The Population Council, Inc. Multi-layered gradient vaginal ring
AU2011238710B2 (en) * 2010-03-28 2015-08-20 Evestra, Inc. Intravaginal drug delivery device
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
BR112014001450A2 (pt) * 2011-07-20 2017-07-18 F Kiser Patrick dispositivos intravaginais para distribuição de droga
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) * 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
KR102272235B1 (ko) * 2016-05-12 2021-07-01 머크 샤프 앤드 돔 코포레이션 항바이러스제의 전달을 위한 약물 전달 시스템
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
EP4628016A3 (en) 2017-10-27 2025-12-17 Axena Health, Inc. Devices, systems, and methods for training pelvic floor muscles
WO2019222856A1 (en) 2018-05-24 2019-11-28 Nureva Inc. Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
AU2019275406B2 (en) 2018-05-24 2024-11-14 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
WO2019226519A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
US20200179274A1 (en) * 2018-12-11 2020-06-11 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
KR102159904B1 (ko) 2020-04-24 2020-09-24 강경원 약물 방출 고리를 구비한 월경컵
WO2022231930A1 (en) 2021-04-26 2022-11-03 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
EP4215181A1 (en) * 2022-01-21 2023-07-26 Sever Pharma Solutions An intravaginal ring
WO2023200974A1 (en) * 2022-04-14 2023-10-19 Yale University Nanoparticles and nanoparticle-releasing vaginal rings
WO2024030116A1 (en) * 2022-08-01 2024-02-08 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
EP4487840A1 (en) 2023-07-07 2025-01-08 Sever Pharma Solutions A three-layered intravaginal ring

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US3995634A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal cavity dispensing means and method
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Also Published As

Publication number Publication date
PE20050815A1 (es) 2005-10-04
KR20060015617A (ko) 2006-02-17
HK1084337A1 (en) 2006-07-28
RU2340344C2 (ru) 2008-12-10
US8333983B2 (en) 2012-12-18
IL171622A (en) 2012-01-31
AU2004241747B2 (en) 2010-03-11
NO20055171D0 (no) 2005-11-03
UA84287C2 (uk) 2008-10-10
WO2004103336A2 (en) 2004-12-02
NZ543652A (en) 2009-06-26
PT1631255E (pt) 2013-01-07
JP4685780B2 (ja) 2011-05-18
EP1631255B1 (en) 2012-10-17
WO2004103336A3 (en) 2005-01-06
CN1794974B (zh) 2010-09-29
US20130078286A1 (en) 2013-03-28
MXPA05012595A (es) 2006-02-22
AR044547A1 (es) 2005-09-21
TWI336627B (en) 2011-02-01
JP2007502316A (ja) 2007-02-08
BRPI0410455B1 (pt) 2018-05-15
AU2004241747A1 (en) 2004-12-02
TW200505519A (en) 2005-02-16
CA2524665C (en) 2011-12-20
ECSP056250A (es) 2006-04-19
HRP20050945A2 (en) 2006-02-28
ES2396100T3 (es) 2013-02-19
US8900615B2 (en) 2014-12-02
RU2005140277A (ru) 2006-06-10
US8858977B2 (en) 2014-10-14
EP1631255A2 (en) 2006-03-08
PL1631255T3 (pl) 2013-03-29
IS2864B (is) 2014-01-15
KR101116267B1 (ko) 2012-03-14
BRPI0410455A (pt) 2006-06-13
NO336456B1 (no) 2015-08-31
CY1113500T1 (el) 2016-06-22
ZA200509450B (en) 2007-03-28
CO5630021A2 (es) 2006-04-28
NO20055171L (no) 2006-01-31
SI1631255T1 (sl) 2013-02-28
US20130115265A1 (en) 2013-05-09
HRP20050945B1 (hr) 2014-03-14
US20060280771A1 (en) 2006-12-14
CN1794974A (zh) 2006-06-28
DK1631255T3 (da) 2013-02-04
BRPI0410455B8 (pt) 2021-05-25
CA2524665A1 (en) 2004-12-02

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