BRPI0410455A - sistema de liberação de drogas, métodos de contracepção, de prover concomitantemente contracepção e tratamento ou prevenção de uma doença sexualmente transmitida, uso do sistema de liberação de drogas, e, método de fabricar o sistema de liberação de drogas em três camadas - Google Patents

sistema de liberação de drogas, métodos de contracepção, de prover concomitantemente contracepção e tratamento ou prevenção de uma doença sexualmente transmitida, uso do sistema de liberação de drogas, e, método de fabricar o sistema de liberação de drogas em três camadas

Info

Publication number
BRPI0410455A
BRPI0410455A BRPI0410455-2A BRPI0410455A BRPI0410455A BR PI0410455 A BRPI0410455 A BR PI0410455A BR PI0410455 A BRPI0410455 A BR PI0410455A BR PI0410455 A BRPI0410455 A BR PI0410455A
Authority
BR
Brazil
Prior art keywords
drug release
release system
drug
prevention
treatment
Prior art date
Application number
BRPI0410455-2A
Other languages
English (en)
Inventor
Rudolf Johannes Jo Groenewegem
Wouter De Graaff
Henk Jan Out
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36701594&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0410455(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of BRPI0410455A publication Critical patent/BRPI0410455A/pt
Publication of BRPI0410455B1 publication Critical patent/BRPI0410455B1/pt
Publication of BRPI0410455B8 publication Critical patent/BRPI0410455B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Nanotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"SISTEMA DE LIBERAçãO DE DROGAS, MéTODOS DE CONTRACEPçãO, DE PROVER CONCOMITANTEMENTE CONTRACEPçãO E TRATAMENTO OU PREVENçãO DE UMA DOENçA SEXUALMENTE TRANSMITIDA, USO DO SISTEMA DE LIBERAçãO DE DROGAS, E, MéTODO DE FABRICAR O SISTEMA DE LIBERAçãO DE DROGAS EM TRêS CAMADAS". A presente invenção provê um sistema de liberação de drogas compreendendo, pelo menos, um compartimento consistindo de (í) um núcleo de polímero termoplástico carregado com drogas, (ii) uma camada intermediária de polímero termoplástico carregada com drogas, e (iii) uma película de polímero termoplástico não medicamentosa, cobrindo a camada intermediária, em que referida camada intermediária é carregada com (a) cristais de um primeiro composto farmaceuticamente ativo e com (b) um segundo composto farmaceuticamente ativo em forma dissolvida e em que o referido núcleo é carregado com referido segundo composto em forma dissolvida.
BRPI0410455A 2003-05-23 2004-05-19 sistema de liberação de drogas, uso do sistema de liberação de drogas, e, método de fabricar o sistema de liberação de drogas em três camadas BRPI0410455B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US47305503P 2003-05-23 2003-05-23
EP03101490.5 2003-05-23
US60/473,055 2003-05-23
EP03101490 2003-05-23
PCT/EP2004/050850 WO2004103336A2 (en) 2003-05-23 2004-05-19 Drug delivery system

Publications (3)

Publication Number Publication Date
BRPI0410455A true BRPI0410455A (pt) 2006-06-13
BRPI0410455B1 BRPI0410455B1 (pt) 2018-05-15
BRPI0410455B8 BRPI0410455B8 (pt) 2021-05-25

Family

ID=36701594

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410455A BRPI0410455B8 (pt) 2003-05-23 2004-05-19 sistema de liberação de drogas, uso do sistema de liberação de drogas, e, método de fabricar o sistema de liberação de drogas em três camadas

Country Status (29)

Country Link
US (3) US8333983B2 (pt)
EP (1) EP1631255B1 (pt)
JP (1) JP4685780B2 (pt)
KR (1) KR101116267B1 (pt)
CN (1) CN1794974B (pt)
AR (1) AR044547A1 (pt)
AU (1) AU2004241747B2 (pt)
BR (1) BRPI0410455B8 (pt)
CA (1) CA2524665C (pt)
CO (1) CO5630021A2 (pt)
CY (1) CY1113500T1 (pt)
DK (1) DK1631255T3 (pt)
EC (1) ECSP056250A (pt)
ES (1) ES2396100T3 (pt)
HR (1) HRP20050945B1 (pt)
IL (1) IL171622A (pt)
IS (1) IS2864B (pt)
MX (1) MXPA05012595A (pt)
NO (1) NO336456B1 (pt)
NZ (1) NZ543652A (pt)
PE (1) PE20050815A1 (pt)
PL (1) PL1631255T3 (pt)
PT (1) PT1631255E (pt)
RU (1) RU2340344C2 (pt)
SI (1) SI1631255T1 (pt)
TW (1) TWI336627B (pt)
UA (1) UA84287C2 (pt)
WO (1) WO2004103336A2 (pt)
ZA (1) ZA200509450B (pt)

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Also Published As

Publication number Publication date
PE20050815A1 (es) 2005-10-04
KR20060015617A (ko) 2006-02-17
HK1084337A1 (en) 2006-07-28
RU2340344C2 (ru) 2008-12-10
US8333983B2 (en) 2012-12-18
IL171622A (en) 2012-01-31
AU2004241747B2 (en) 2010-03-11
NO20055171D0 (no) 2005-11-03
UA84287C2 (uk) 2008-10-10
WO2004103336A2 (en) 2004-12-02
NZ543652A (en) 2009-06-26
PT1631255E (pt) 2013-01-07
JP4685780B2 (ja) 2011-05-18
EP1631255B1 (en) 2012-10-17
WO2004103336A3 (en) 2005-01-06
CN1794974B (zh) 2010-09-29
US20130078286A1 (en) 2013-03-28
MXPA05012595A (es) 2006-02-22
AR044547A1 (es) 2005-09-21
TWI336627B (en) 2011-02-01
JP2007502316A (ja) 2007-02-08
BRPI0410455B1 (pt) 2018-05-15
AU2004241747A1 (en) 2004-12-02
TW200505519A (en) 2005-02-16
CA2524665C (en) 2011-12-20
ECSP056250A (es) 2006-04-19
HRP20050945A2 (en) 2006-02-28
ES2396100T3 (es) 2013-02-19
US8900615B2 (en) 2014-12-02
RU2005140277A (ru) 2006-06-10
IS8086A (is) 2005-10-24
US8858977B2 (en) 2014-10-14
EP1631255A2 (en) 2006-03-08
PL1631255T3 (pl) 2013-03-29
IS2864B (is) 2014-01-15
KR101116267B1 (ko) 2012-03-14
NO336456B1 (no) 2015-08-31
CY1113500T1 (el) 2016-06-22
ZA200509450B (en) 2007-03-28
CO5630021A2 (es) 2006-04-28
NO20055171L (no) 2006-01-31
SI1631255T1 (sl) 2013-02-28
US20130115265A1 (en) 2013-05-09
HRP20050945B1 (hr) 2014-03-14
US20060280771A1 (en) 2006-12-14
CN1794974A (zh) 2006-06-28
DK1631255T3 (da) 2013-02-04
BRPI0410455B8 (pt) 2021-05-25
CA2524665A1 (en) 2004-12-02

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