IS8567A - Efnasmíð á heterósýklískum efnasamböndum sem innihalda fimm- eða sex-atóma hringi - Google Patents

Efnasmíð á heterósýklískum efnasamböndum sem innihalda fimm- eða sex-atóma hringi

Info

Publication number
IS8567A
IS8567A IS8567A IS8567A IS8567A IS 8567 A IS8567 A IS 8567A IS 8567 A IS8567 A IS 8567A IS 8567 A IS8567 A IS 8567A IS 8567 A IS8567 A IS 8567A
Authority
IS
Iceland
Prior art keywords
nitrogen
halo
carbon
och2
excess
Prior art date
Application number
IS8567A
Other languages
English (en)
Other versions
IS2634B (is
Inventor
V. Schally Andrew
Attila Nagy
Cai Ren Zhi
Original Assignee
Administrators Of The Tulane Educational Fund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24247176&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8567(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Administrators Of The Tulane Educational Fund filed Critical Administrators Of The Tulane Educational Fund
Publication of IS8567A publication Critical patent/IS8567A/is
Publication of IS2634B publication Critical patent/IS2634B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS8567A 1995-11-27 2006-11-09 Efnasmíð á heterósýklískum efnasamböndum sem innihalda fimm- eða sex-atóma hringi IS2634B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/562,652 US5843903A (en) 1995-11-27 1995-11-27 Targeted cytotoxic anthracycline analogs
PCT/EP1996/005029 WO1997019954A1 (en) 1995-11-27 1996-11-14 Targeted cytotoxic anthracycline analogs

Publications (2)

Publication Number Publication Date
IS8567A true IS8567A (is) 2006-11-09
IS2634B IS2634B (is) 2010-06-15

Family

ID=24247176

Family Applications (2)

Application Number Title Priority Date Filing Date
IS4734A IS2178B (is) 1995-11-27 1998-05-05 Merktar frumueiturs-antrasýklín hliðstæður
IS8567A IS2634B (is) 1995-11-27 2006-11-09 Efnasmíð á heterósýklískum efnasamböndum sem innihalda fimm- eða sex-atóma hringi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IS4734A IS2178B (is) 1995-11-27 1998-05-05 Merktar frumueiturs-antrasýklín hliðstæður

Country Status (27)

Country Link
US (2) US5843903A (is)
EP (2) EP0863917B1 (is)
JP (2) JP3987575B2 (is)
KR (2) KR100467899B1 (is)
CN (2) CN1166597C (is)
AT (2) ATE401305T1 (is)
AU (1) AU709539B2 (is)
BR (1) BR9611647B1 (is)
CA (2) CA2238574C (is)
CZ (1) CZ297297B6 (is)
DE (2) DE69630233T2 (is)
DK (2) DK1384710T3 (is)
EA (1) EA001372B1 (is)
ES (2) ES2205067T3 (is)
HK (1) HK1052920B (is)
HU (1) HU229870B1 (is)
IL (3) IL134685A (is)
IS (2) IS2178B (is)
MX (1) MX9804119A (is)
NO (2) NO324035B1 (is)
NZ (1) NZ322054A (is)
PL (3) PL191781B1 (is)
PT (2) PT863917E (is)
SK (2) SK284392B6 (is)
UA (1) UA67722C2 (is)
WO (1) WO1997019954A1 (is)
ZA (1) ZA969709B (is)

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US6528481B1 (en) 1999-02-16 2003-03-04 The Burnam Institute NG2/HM proteoglycan-binding peptides that home to angiogenic vasculature and related methods
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US7420030B2 (en) 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
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EP1900742A1 (en) 2006-09-07 2008-03-19 AEterna Zentaris GmbH Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof
US20100087370A1 (en) * 2007-02-14 2010-04-08 The General Hospital Corporation Modulation of nitric oxide signaling to normalize tumor vasculature
RU2377247C2 (ru) * 2007-12-27 2009-12-27 Федеральное государственное образовательное учреждение высшего профессионального образования Санкт-Петербургский государственный университет Молекулярный конъюгат на основе синтетических аналогов люлиберина и его применение в качестве средства доставки днк в клетки гормон-чувствительных опухолей (варианты)
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AU2009235897B2 (en) * 2008-04-11 2012-04-12 Tianjin Hemay Oncology Pharmaceutical Co., Ltd Anthracycline antibiotic derivatives with high activity, preparation methods and uses thereof
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Also Published As

Publication number Publication date
AU7572296A (en) 1997-06-19
PT1384710E (pt) 2008-10-08
CA2238574C (en) 2004-10-19
DK1384710T3 (da) 2008-11-17
WO1997019954A1 (en) 1997-06-05
DE69630233T2 (de) 2004-08-05
KR19990071672A (ko) 1999-09-27
IS2178B (is) 2006-12-15
UA67722C2 (en) 2004-07-15
SK62898A3 (en) 1999-06-11
HUP9903771A3 (en) 2000-07-28
PL326865A1 (en) 1998-10-26
EP0863917B1 (en) 2003-10-01
BR9611647B1 (pt) 2010-03-09
HUP9903771A2 (hu) 2000-02-28
CZ135798A3 (cs) 1998-10-14
NZ322054A (en) 1999-04-29
CN1202903A (zh) 1998-12-23
KR20040037176A (ko) 2004-05-04
HK1052920A1 (en) 2003-10-03
EP0863917A1 (en) 1998-09-16
IL119691A (en) 2002-02-10
IS2634B (is) 2010-06-15
CN1405127A (zh) 2003-03-26
CZ297297B6 (cs) 2006-11-15
EP1384710B1 (en) 2008-07-16
ATE251179T1 (de) 2003-10-15
IL134685A (en) 2002-12-01
AU709539B2 (en) 1999-09-02
NO982252D0 (no) 1998-05-15
ZA969709B (en) 1997-08-25
IL134685A0 (en) 2001-04-30
PL188786B1 (pl) 2005-04-29
NO324035B1 (no) 2007-07-30
EA001372B1 (ru) 2001-02-26
KR100445754B1 (ko) 2004-12-08
US6184374B1 (en) 2001-02-06
PL191781B1 (pl) 2006-07-31
HK1052920B (zh) 2005-03-04
ES2205067T3 (es) 2004-05-01
EP1384710A1 (en) 2004-01-28
JP4778405B2 (ja) 2011-09-21
KR100467899B1 (ko) 2005-01-24
MX9804119A (es) 1998-09-30
PT863917E (pt) 2004-02-27
CN1166597C (zh) 2004-09-15
IS4734A (is) 1998-05-05
SK284392B6 (sk) 2005-03-04
IL119691A0 (en) 1997-02-18
BR9611647A (pt) 1999-02-23
JP2000502055A (ja) 2000-02-22
EA199800492A1 (ru) 1998-12-24
CA2238574A1 (en) 1997-06-05
US5843903A (en) 1998-12-01
DK0863917T3 (da) 2004-01-19
NO982252L (no) 1998-05-15
JP3987575B2 (ja) 2007-10-10
NO20051111L (no) 2005-03-01
HK1017363A1 (en) 1999-11-19
ES2310222T3 (es) 2009-01-01
HU229870B1 (en) 2014-10-28
DE69637604D1 (de) 2008-08-28
CN1137136C (zh) 2004-02-04
PL187230B1 (pl) 2004-06-30
CA2471775A1 (en) 1997-06-05
JP2007045845A (ja) 2007-02-22
SK284672B6 (sk) 2005-08-04
DE69630233D1 (de) 2003-11-06
ATE401305T1 (de) 2008-08-15
CA2471775C (en) 2008-01-29

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