IS8920A - 3-(Fenýl eða kínólyl)þíó- 1H-idnól-1-ediksýru afleður sem mótarar á virkni CRTh2 vitaka. - Google Patents

3-(Fenýl eða kínólyl)þíó- 1H-idnól-1-ediksýru afleður sem mótarar á virkni CRTh2 vitaka.

Info

Publication number: IS8920A
Authority: IS; Iceland
Prior art keywords: idanol; quinolyl; thio; phenyl; activity
Prior art date: 2003-05-27

Application number

IS8920A

Other languages

English (en)

Inventor

Roger Bonnert

Rukshana Mohammed

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-27

Filing date

2010-08-09

Publication date

2010-08-09

2010-08-09 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2010-08-09 Publication of IS8920A publication Critical patent/IS8920A/is

Links

239000005557 antagonist Substances 0.000 title 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
125000005493 quinolyl group Chemical group 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IS8920A 2003-05-27 2010-08-09 3-(Fenýl eða kínólyl)þíó- 1H-idnól-1-ediksýru afleður sem mótarar á virkni CRTh2 vitaka. IS8920A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0301569A SE0301569D0 (sv)	2003-05-27	2003-05-27	Novel compounds
SE0302305A SE0302305D0 (sv)	2003-05-27	2003-08-27	Novel Compounds

Publications (1)

Publication Number	Publication Date
IS8920A true IS8920A (is)	2010-08-09

Family

ID=33492578

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IS8189A IS2722B (is)	2003-05-27	2005-12-20	1, 2, 3, 4- Tetrasetin indól til meðhöndlunar á öndunarfærasjúkdómum
IS8920A IS8920A (is)	2003-05-27	2010-08-09	3-(Fenýl eða kínólyl)þíó- 1H-idnól-1-ediksýru afleður sem mótarar á virkni CRTh2 vitaka.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
IS8189A IS2722B (is)	2003-05-27	2005-12-20	1, 2, 3, 4- Tetrasetin indól til meðhöndlunar á öndunarfærasjúkdómum

Country Status (30)

Country	Link
US (4)	US7687535B2 (is)
EP (3)	EP2025670B1 (is)
JP (2)	JP4541361B2 (is)
KR (3)	KR101067586B1 (is)
CN (2)	CN1795174B (is)
AR (1)	AR044552A1 (is)
AT (3)	ATE502010T1 (is)
AU (1)	AU2004242624B2 (is)
BR (1)	BRPI0410711B8 (is)
CA (1)	CA2526866C (is)
CO (1)	CO5630030A2 (is)
CY (3)	CY1109104T1 (is)
DE (2)	DE602004020072D1 (is)
DK (3)	DK2281815T3 (is)
ES (3)	ES2322650T3 (is)
HR (3)	HRP20090281T1 (is)
IL (4)	IL171928A (is)
IS (2)	IS2722B (is)
MX (1)	MXPA05012680A (is)
MY (1)	MY144483A (is)
NO (1)	NO20056130L (is)
NZ (1)	NZ543722A (is)
PL (3)	PL2281815T3 (is)
PT (3)	PT1656346E (is)
RU (1)	RU2361860C2 (is)
SE (2)	SE0301569D0 (is)
SI (3)	SI1656346T1 (is)
TW (2)	TWI328004B (is)
WO (1)	WO2004106302A1 (is)
ZA (1)	ZA200509598B (is)

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2003
- 2003-05-27 SE SE0301569A patent/SE0301569D0/xx unknown
- 2003-08-27 SE SE0302305A patent/SE0302305D0/xx unknown
2004
- 2004-05-19 TW TW093114113A patent/TWI328004B/zh not_active IP Right Cessation
- 2004-05-19 TW TW099109193A patent/TW201024261A/zh unknown
- 2004-05-24 AR ARP040101792A patent/AR044552A1/es unknown
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- 2004-05-25 PT PT04734774T patent/PT1656346E/pt unknown
- 2004-05-25 EP EP08165755A patent/EP2025670B1/en not_active Expired - Lifetime
- 2004-05-25 PL PL10180348T patent/PL2281815T3/pl unknown
- 2004-05-25 AT AT08165755T patent/ATE502010T1/de active
- 2004-05-25 CN CN2004800146027A patent/CN1795174B/zh not_active Expired - Fee Related
- 2004-05-25 JP JP2006532212A patent/JP4541361B2/ja not_active Expired - Fee Related
- 2004-05-25 DK DK10180348.4T patent/DK2281815T3/da active
- 2004-05-25 WO PCT/SE2004/000808 patent/WO2004106302A1/en not_active Ceased
- 2004-05-25 AU AU2004242624A patent/AU2004242624B2/en not_active Ceased
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- 2004-05-25 RU RU2005137403/04A patent/RU2361860C2/ru active
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- 2004-05-25 DK DK08165755.3T patent/DK2025670T3/da active
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- 2004-05-25 KR KR1020057022513A patent/KR101067586B1/ko not_active Expired - Fee Related
- 2004-05-25 KR KR1020117009790A patent/KR20110050754A/ko not_active Ceased
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2005
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- 2005-12-22 NO NO20056130A patent/NO20056130L/no not_active Application Discontinuation
2008
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2009
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2010
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Also Published As

Publication number	Publication date
AR044552A1 (es)	2005-09-21
DE602004031894D1 (de)	2011-04-28
TWI328004B (en)	2010-08-01
KR20060015303A (ko)	2006-02-16
RU2361860C2 (ru)	2009-07-20
EP1656346A1 (en)	2006-05-17
JP4541361B2 (ja)	2010-09-08
HRP20110359T1 (hr)	2011-06-30
CY1109104T1 (el)	2014-07-02
ES2361485T3 (es)	2011-06-17
HRP20120390T1 (hr)	2012-06-30
BRPI0410711B8 (pt)	2021-05-25
ATE502010T1 (de)	2011-04-15
HK1126773A1 (en)	2009-09-11
WO2004106302A1 (en)	2004-12-09
US20120178764A1 (en)	2012-07-12
TW201024261A (en)	2010-07-01
SI2281815T1 (sl)	2012-06-29
CY1112853T1 (el)	2016-02-10
PT2281815E (pt)	2012-05-24
NO20056130L (no)	2006-02-27
RU2005137403A (ru)	2006-05-27
PT2025670E (pt)	2011-05-24
IS2722B (is)	2011-03-15
CN1795174B (zh)	2011-09-28
DK1656346T3 (da)	2009-06-15
ES2382606T3 (es)	2012-06-11
CN102391171A (zh)	2012-03-28
SE0302305D0 (sv)	2003-08-27
IL171928A0 (en)	2006-04-10
SI1656346T1 (sl)	2009-08-31
EP2281815B1 (en)	2012-04-04
PT1656346E (pt)	2009-05-20
US7687535B2 (en)	2010-03-30
HK1149563A1 (en)	2011-10-07
DK2025670T3 (da)	2011-06-06
IL194872A0 (en)	2011-08-01
IS8189A (is)	2005-12-20
ZA200509598B (en)	2006-12-27
PL2025670T3 (pl)	2011-07-29
MY144483A (en)	2011-09-30
CA2526866C (en)	2012-10-16
SI2025670T1 (sl)	2011-06-30
EP2025670B1 (en)	2011-03-16
US20090163518A1 (en)	2009-06-25
HK1090635A1 (zh)	2006-12-29
US20110263614A1 (en)	2011-10-27
EP1656346B1 (en)	2009-03-18
DK2281815T3 (da)	2012-06-18
HRP20090281T1 (hr)	2009-06-30
JP2010155862A (ja)	2010-07-15
KR20110051297A (ko)	2011-05-17
KR20110050754A (ko)	2011-05-16
IL212265A0 (en)	2011-06-30
ATE425965T1 (de)	2009-04-15
IL212371A0 (en)	2011-06-30
AU2004242624A1 (en)	2004-12-09
CA2526866A1 (en)	2004-12-09
BRPI0410711A (pt)	2006-06-13
BRPI0410711B1 (pt)	2018-09-25
CN1795174A (zh)	2006-06-28
PL1656346T3 (pl)	2009-07-31
CO5630030A2 (es)	2006-04-28
TW200510301A (en)	2005-03-16
NZ543722A (en)	2007-05-31
EP2025670A1 (en)	2009-02-18
AU2004242624B2 (en)	2008-03-13
PL2281815T3 (pl)	2012-08-31
KR101067535B1 (ko)	2011-09-27
CY1111469T1 (el)	2015-08-05
IL171928A (en)	2011-06-30
US20080249110A1 (en)	2008-10-09
JP2007501269A (ja)	2007-01-25
KR101067586B1 (ko)	2011-09-27
DE602004020072D1 (de)	2009-04-30
ATE552243T1 (de)	2012-04-15
ES2322650T3 (es)	2009-06-24
MXPA05012680A (es)	2006-02-08
SE0301569D0 (sv)	2003-05-27
EP2281815A1 (en)	2011-02-09

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DK1648867T3 (da)	2013-12-16	Ppar-aktive forbindelser
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DE60322340D1 (de)	2008-09-04	Riechstoffverbindung
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RU2002107079A (ru)	2003-11-20	Вещество, обладающее седативным действием
ITMI20022704A1 (it)	2004-06-21	Procedimento per la produzione di mesitilene e durene.
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ITBZ20040033A1 (it)	2004-10-09	Impianto di rilevamento dell'umidita'.
ES1052266Y (es)	2003-03-16	Comedero para animales.