IT1223390B - Prostacicline - Google Patents

Prostacicline

Info

Publication number: IT1223390B
Authority: IT; Italy
Prior art keywords: prostacyclin
Prior art date: 1986-12-01

Application number

IT22814/87A

Other languages

English (en)

Italian (it)

Other versions

IT8722814A0 (it

Inventor

George William Holland

Hans Maag

Perry Rosen

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-01

Filing date

1987-11-30

Publication date

1990-09-19

1987-11-30 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1987-11-30 Publication of IT8722814A0 publication Critical patent/IT8722814A0/it

1990-09-19 Application granted granted Critical

1990-09-19 Publication of IT1223390B publication Critical patent/IT1223390B/it

Links

KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 title 1
229960001123 epoprostenol Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)

IT22814/87A 1986-12-01 1987-11-30 Prostacicline IT1223390B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US93652286A	1986-12-01	1986-12-01

Publications (2)

Publication Number	Publication Date
IT8722814A0 IT8722814A0 (it)	1987-11-30
IT1223390B true IT1223390B (it)	1990-09-19

Family

ID=25468757

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT22814/87A IT1223390B (it)	1986-12-01	1987-11-30	Prostacicline

Country Status (14)

Country	Link
JP (1)	JPS63145275A (da)
AT (1)	AT391697B (da)
AU (1)	AU597128B2 (da)
BE (1)	BE1001271A5 (da)
CH (1)	CH674363A5 (da)
DE (1)	DE3740595A1 (da)
DK (1)	DK627787A (da)
FR (1)	FR2607501A1 (da)
GB (1)	GB2198130B (da)
IT (1)	IT1223390B (da)
NL (1)	NL8702855A (da)
NZ (1)	NZ222723A (da)
SE (1)	SE8704770L (da)
ZA (1)	ZA878947B (da)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4565827A (en) *	1980-10-27	1986-01-21	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T.	7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
DE3176313D1 (en) *	1980-12-09	1987-08-20	Teijin Ltd	Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
CH648556A5 (de) *	1981-03-11	1985-03-29	Hoffmann La Roche	Fluorprostacycline.
US4558142A (en) *	1981-03-11	1985-12-10	Hoffmann-La Roche Inc.	7-Fluoro-prostacyclin analogs
JPS5867682A (ja) *	1981-10-16	1983-04-22	Teijin Ltd	フルオロｐｇｉ↓２類の製法
JPS58150583A (ja) *	1982-03-04	1983-09-07	Teijin Ltd	新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
JPS59227888A (ja) *	1983-06-10	1984-12-21	Asahi Glass Co Ltd	７−フルオロプロスタグランジン類の製造方法
US4634782A (en) *	1985-06-24	1987-01-06	Hoffmann-La Roche Inc.	7-fluoro-dihydro PGI compounds

1987
- 1987-11-06 CH CH4345/87A patent/CH674363A5/de not_active IP Right Cessation
- 1987-11-27 NL NL8702855A patent/NL8702855A/nl not_active Application Discontinuation
- 1987-11-27 NZ NZ222723A patent/NZ222723A/en unknown
- 1987-11-27 FR FR8716485A patent/FR2607501A1/fr active Pending
- 1987-11-27 ZA ZA878947A patent/ZA878947B/xx unknown
- 1987-11-27 JP JP62297860A patent/JPS63145275A/ja active Pending
- 1987-11-30 AT AT0313887A patent/AT391697B/de not_active IP Right Cessation
- 1987-11-30 IT IT22814/87A patent/IT1223390B/it active
- 1987-11-30 SE SE8704770A patent/SE8704770L/xx not_active Application Discontinuation
- 1987-11-30 AU AU81907/87A patent/AU597128B2/en not_active Ceased
- 1987-11-30 BE BE8701358A patent/BE1001271A5/fr not_active IP Right Cessation
- 1987-11-30 DK DK627787A patent/DK627787A/da not_active Application Discontinuation
- 1987-11-30 GB GB8727991A patent/GB2198130B/en not_active Expired - Lifetime
- 1987-11-30 DE DE19873740595 patent/DE3740595A1/de not_active Withdrawn

Also Published As

Publication number	Publication date
AT391697B (de)	1990-11-12
DK627787A (da)	1988-06-02
ZA878947B (en)	1988-06-01
DE3740595A1 (de)	1988-06-16
GB2198130A (en)	1988-06-08
GB2198130B (en)	1990-08-08
DK627787D0 (da)	1987-11-30
SE8704770L (sv)	1988-06-02
NZ222723A (en)	1990-11-27
AU597128B2 (en)	1990-05-24
SE8704770D0 (sv)	1987-11-30
BE1001271A5 (fr)	1989-09-12
FR2607501A1 (fr)	1988-06-03
CH674363A5 (da)	1990-05-31
JPS63145275A (ja)	1988-06-17
ATA313887A (de)	1990-05-15
NL8702855A (nl)	1988-07-01
GB8727991D0 (en)	1988-01-06
AU8190787A (en)	1988-06-02
IT8722814A0 (it)	1987-11-30

Publication	Publication Date	Title
DK409187D0 (da)	1987-08-05	Loefteslynge
FI871742A0 (fi)	1987-04-21	Traebearbetningsfraes
DK436987D0 (da)	1987-08-21	Gel-forpakning
DK83687A (da)	1987-08-21	Aeltemaskine
DK492587A (da)	1987-09-18	Substituerede indolquinoxaliner
DK220387D0 (da)	1987-04-30	Aeion-sensorae
DK157746C (da)	1990-07-23	Loeftekrog
FI90608C (fi)	1994-02-25	Taajuussyntesointilaite
FR2608909B1 (fr)	1992-03-27	Amnioscope
DK438087A (da)	1988-02-23	Schistosomprotein
DK290487A (da)	1987-12-10	Substituerede 3-amino-2-benzoylcyklohex-2-enoner
DK477187D0 (da)	1987-09-11	Klaebekomposition
DK134688D0 (da)	1988-03-11	Fluidumpudeindretning
BR8605161A (pt)	1988-04-26	Palmilha
DK406888D0 (da)	1988-07-20	Stige
ATA246886A (de)	1988-01-15	Schachtsystem
DK249087A (da)	1987-11-17	Alfa-halogenpyruvatoxim
FR2599154B1 (fr)	1990-05-11	Altimetre-radar
DK145387A (da)	1987-09-25	Naphthalenderivater
IT1223391B (it)	1990-09-19	Prostacicline
ES292764Y (es)	1987-03-01	Carrito transportador-expositor
IS3238A7 (is)	1987-10-02	Keðjulás
DK627787D0 (da)	1987-11-30	Prostacycliner
ES1000391Y (es)	1989-12-01	Formulario unibanda
FI923615A0 (fi)	1992-08-12	Substituoituja N3-tioasyylisemikarbatsideja