IT8048997A0 - 4-aroilimidazol-2-oni dotati di pro prieta' anti-ipertensive cardiotoniche e antitrombotiche e procedimento per la loro preparazione - Google Patents

4-aroilimidazol-2-oni dotati di pro prieta' anti-ipertensive cardiotoniche e antitrombotiche e procedimento per la loro preparazione

Info

Publication number: IT8048997A0
Authority: IT; Italy
Prior art keywords: aroilimidazol; cardiotonic; ons; hypertensive; procedure
Prior art date: 1979-06-18

Application number

IT8048997A

Other languages

English (en)

Other versions

IT1143922B (it

Inventor

Richard A Schnettler

Richard C Dage

Grisar J Martin

Original Assignee

Richardson Merrell Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-18

Filing date

1980-06-17

Publication date

1980-06-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT8048997(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-06-17 Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc

1980-06-17 Publication of IT8048997A0 publication Critical patent/IT8048997A0/it

1986-10-29 Application granted granted Critical

1986-10-29 Publication of IT1143922B publication Critical patent/IT1143922B/it

Links

230000003276 anti-hypertensive effect Effects 0.000 title 1
230000002785 anti-thrombosis Effects 0.000 title 1
230000003177 cardiotonic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IT48997/80A 1979-06-18 1980-06-17 4-aroilimidazol-2-oni dotati di proprieta'anti-ipertensive cardiotoniche e antitrombotiche e procedimento per la loro preparazione IT1143922B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4980879A	1979-06-18	1979-06-18
US11920780A	1980-02-07	1980-02-07

Publications (2)

Publication Number	Publication Date
IT8048997A0 true IT8048997A0 (it)	1980-06-17
IT1143922B IT1143922B (it)	1986-10-29

Family

ID=26727558

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT48997/80A IT1143922B (it)	1979-06-18	1980-06-17	4-aroilimidazol-2-oni dotati di proprieta'anti-ipertensive cardiotoniche e antitrombotiche e procedimento per la loro preparazione

Country Status (20)

Country	Link
AT (1)	AT375349B (it)
AU (1)	AU532783B2 (it)
CA (1)	CA1132554A (it)
CH (1)	CH646155A5 (it)
DE (1)	DE3021792A1 (it)
DK (1)	DK160269C (it)
ES (1)	ES8105299A1 (it)
FR (1)	FR2459233A1 (it)
GB (1)	GB2055364B (it)
HK (1)	HK61486A (it)
HU (1)	HU186736B (it)
IE (1)	IE50646B1 (it)
IL (1)	IL60243A (it)
IT (1)	IT1143922B (it)
MY (1)	MY8600709A (it)
NL (2)	NL193752C (it)
NO (1)	NO152841C (it)
NZ (1)	NZ193935A (it)
PH (1)	PH18683A (it)
SE (2)	SE447107B (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH18106A (en) *	1981-02-18	1985-03-21	Merrell Dow Pharma	Novel-4-aroylimidazol-2-ones
US4405628A (en) *	1981-03-05	1983-09-20	Merrell Dow Pharmaceuticals Inc.	4-Pyridylimidazolones and method of use
US4329471A (en) *	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4371737A (en) *	1981-05-04	1983-02-01	Merrell Dow Pharmaceuticals Inc.	5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329470A (en)	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
ZA822990B (en) *	1981-05-04	1983-03-30	Merrell Dow Pharma	4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones
US4526981A (en) *	1981-05-04	1985-07-02	Merrell Dow Pharmaceuticals Inc.	[1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4381393A (en) *	1981-05-04	1983-04-26	Merrell Dow Pharmaceuticals Inc.	4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4367236A (en)	1981-11-04	1983-01-04	Merrell Dow Pharmaceuticals Inc.	Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) *	1981-11-04	1983-10-18	Merrell Dow Pharmaceuticals Inc.	Cardiotonic 4-aroylimidazolidin-2-ones
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
JP2007530566A (ja) *	2004-03-22	2007-11-01	ミオゲンインコーポレイティッド	（ｒ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
CA2560528A1 (en) *	2004-03-22	2005-10-06	Myogen, Inc.	(s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
JP2009514969A (ja)	2005-11-09	2009-04-09	コンビナトアールエックスインコーポレーティッド	医学的状態を治療するための方法、組成物、およびキット
MX354786B (es)	2007-06-04	2018-03-21	Synergy Pharmaceuticals Inc	Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2522968T3 (es)	2008-06-04	2014-11-19	Synergy Pharmaceuticals Inc.	Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en)	2008-07-16	2015-02-19	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
DK2681236T3 (en)	2011-03-01	2018-04-16	Synergy Pharmaceuticals Inc	PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
WO2014131024A2 (en)	2013-02-25	2014-08-28	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
AU2014235215A1 (en)	2013-03-15	2015-10-01	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
AU2014235209B2 (en)	2013-03-15	2018-06-14	Bausch Health Ireland Limited	Guanylate cyclase receptor agonists combined with other drugs
BR112015030326A2 (pt)	2013-06-05	2017-08-29	Synergy Pharmaceuticals Inc	Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
AU2014305843B2 (en)	2013-08-09	2019-08-29	Ardelyx, Inc.	Compounds and methods for inhibiting phosphate transport
EP4706758A3 (en)	2019-05-21	2026-05-06	Ardelyx, Inc.	Methods for inhibiting phosphate transport
CN114539157B (zh) *	2022-03-03	2023-12-22	曲靖师范学院	一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2441933A (en) *	1945-07-30	1948-05-18	Hoffmann La Roche	Substituted imidazolones and process of making them

1980
- 1980-06-04 NZ NZ193935A patent/NZ193935A/en unknown
- 1980-06-05 IE IE1162/80A patent/IE50646B1/en not_active IP Right Cessation
- 1980-06-06 AU AU59118/80A patent/AU532783B2/en not_active Expired
- 1980-06-06 SE SE8004253A patent/SE447107B/sv not_active IP Right Cessation
- 1980-06-06 IL IL60243A patent/IL60243A/xx unknown
- 1980-06-09 ES ES492255A patent/ES8105299A1/es not_active Expired
- 1980-06-11 DE DE19803021792 patent/DE3021792A1/de active Granted
- 1980-06-13 AT AT0314280A patent/AT375349B/de not_active IP Right Cessation
- 1980-06-16 CH CH462780A patent/CH646155A5/de not_active IP Right Cessation
- 1980-06-16 PH PH24143A patent/PH18683A/en unknown
- 1980-06-17 DK DK259080A patent/DK160269C/da not_active IP Right Cessation
- 1980-06-17 IT IT48997/80A patent/IT1143922B/it active Protection Beyond IP Right Term
- 1980-06-17 NO NO801796A patent/NO152841C/no unknown
- 1980-06-17 CA CA354,197A patent/CA1132554A/en not_active Expired
- 1980-06-17 NL NL8003498A patent/NL193752C/nl not_active IP Right Cessation
- 1980-06-17 FR FR8013434A patent/FR2459233A1/fr active Granted
- 1980-06-17 HU HU801506A patent/HU186736B/hu unknown
- 1980-06-18 GB GB8019898A patent/GB2055364B/en not_active Expired
1985
- 1985-03-25 SE SE8501452A patent/SE464559B/sv not_active IP Right Cessation
1986
- 1986-08-21 HK HK614/86A patent/HK61486A/xx not_active IP Right Cessation
- 1986-12-30 MY MY709/86A patent/MY8600709A/xx unknown
2000
- 2000-09-04 NL NL300015C patent/NL300015I1/nl unknown

Also Published As

Publication number	Publication date
SE447107B (sv)	1986-10-27
CA1132554A (en)	1982-09-28
AU5911880A (en)	1981-01-08
SE464559B (sv)	1991-05-13
PH18683A (en)	1985-08-29
NL193752B (nl)	2000-05-01
NO801796L (no)	1980-12-19
AU532783B2 (en)	1983-10-13
AT375349B (de)	1984-07-25
CH646155A5 (de)	1984-11-15
IT1143922B (it)	1986-10-29
FR2459233B1 (it)	1983-09-23
DE3021792A1 (de)	1981-01-22
NL300015I2 (nl)	2000-10-02
IL60243A (en)	1987-01-30
HU186736B (en)	1985-09-30
DK259080A (da)	1980-12-19
SE8501452L (sv)	1985-03-25
DK160269B (da)	1991-02-18
IL60243A0 (en)	1980-09-16
DE3021792C2 (it)	1989-08-10
NO152841B (no)	1985-08-19
GB2055364A (en)	1981-03-04
NZ193935A (en)	1985-05-31
NL8003498A (nl)	1980-12-22
IE50646B1 (en)	1986-06-11
GB2055364B (en)	1983-06-08
NO152841C (no)	1985-11-27
ES492255A0 (es)	1981-06-01
HK61486A (en)	1986-08-29
NL300015I1 (nl)	2000-11-01
ES8105299A1 (es)	1981-06-01
ATA314280A (de)	1983-12-15
SE8004253L (sv)	1980-12-19
IE801162L (en)	1980-12-18
MY8600709A (en)	1986-12-31
SE8501452D0 (sv)	1985-03-25
FR2459233A1 (fr)	1981-01-09
DK160269C (da)	1991-07-22
NL193752C (nl)	2000-09-04

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Legal Events

Date	Code	Title	Description
1992-04-24	ITCP	Complementary protection certificate	Free format text: CCP 156
1992-11-13	MEDD	Supplementary protection certificate for pharmaceutical products: granted	Free format text: CCP 156, 19920424; MERREL DOW PHARMACEUTICALS INC.
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19950419