SE8004253L - Nya 4-aroylimidazol-2-oner - Google Patents

Nya 4-aroylimidazol-2-oner

Info

Publication number: SE8004253L
Authority: SE; Sweden
Prior art keywords: alkyl; phenyl; hydrogen; alkoxy; hydroxy
Prior art date: 1979-06-18

Application number

SE8004253A

Other languages

English (en)

Other versions

SE447107B (sv

Inventor

R A Schnettler

R C Dage

J M Grisar

Original Assignee

Richardson Merrell Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-18

Filing date

1980-06-06

Publication date

1980-12-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE8004253(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-06-06 Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc

1980-12-19 Publication of SE8004253L publication Critical patent/SE8004253L/sv

1986-10-27 Publication of SE447107B publication Critical patent/SE447107B/sv

Links

125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
-1 pyrrolidino, piperidino, morpholino, piperazino Chemical group 0.000 abstract 2
125000001424 substituent group Chemical group 0.000 abstract 2
125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
206010019280 Heart failures Diseases 0.000 abstract 1
208000001953 Hypotension Diseases 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
230000036543 hypotension Effects 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SE8004253A 1979-06-18 1980-06-06 Nya 4-aroylimidazol-2-oner SE447107B (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4980879A	1979-06-18	1979-06-18
US11920780A	1980-02-07	1980-02-07

Publications (2)

Publication Number	Publication Date
SE8004253L true SE8004253L (sv)	1980-12-19
SE447107B SE447107B (sv)	1986-10-27

Family

ID=26727558

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE8004253A SE447107B (sv)	1979-06-18	1980-06-06	Nya 4-aroylimidazol-2-oner
SE8501452A SE464559B (sv)	1979-06-18	1985-03-25	Farmaceutisk komposition innehaallande 4-aroylimidazol-2-oner med antihypertensiv, kardioton och antitrombotisk verkan

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE8501452A SE464559B (sv)	1979-06-18	1985-03-25	Farmaceutisk komposition innehaallande 4-aroylimidazol-2-oner med antihypertensiv, kardioton och antitrombotisk verkan

Country Status (20)

Country	Link
AT (1)	AT375349B (sv)
AU (1)	AU532783B2 (sv)
CA (1)	CA1132554A (sv)
CH (1)	CH646155A5 (sv)
DE (1)	DE3021792A1 (sv)
DK (1)	DK160269C (sv)
ES (1)	ES492255A0 (sv)
FR (1)	FR2459233A1 (sv)
GB (1)	GB2055364B (sv)
HK (1)	HK61486A (sv)
HU (1)	HU186736B (sv)
IE (1)	IE50646B1 (sv)
IL (1)	IL60243A (sv)
IT (1)	IT1143922B (sv)
MY (1)	MY8600709A (sv)
NL (2)	NL193752C (sv)
NO (1)	NO152841C (sv)
NZ (1)	NZ193935A (sv)
PH (1)	PH18683A (sv)
SE (2)	SE447107B (sv)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH18106A (en) *	1981-02-18	1985-03-21	Merrell Dow Pharma	Novel-4-aroylimidazol-2-ones
US4405628A (en) *	1981-03-05	1983-09-20	Merrell Dow Pharmaceuticals Inc.	4-Pyridylimidazolones and method of use
US4381393A (en) *	1981-05-04	1983-04-26	Merrell Dow Pharmaceuticals Inc.	4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4371737A (en) *	1981-05-04	1983-02-01	Merrell Dow Pharmaceuticals Inc.	5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
ZA822990B (en) *	1981-05-04	1983-03-30	Merrell Dow Pharma	4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones
US4526981A (en) *	1981-05-04	1985-07-02	Merrell Dow Pharmaceuticals Inc.	[1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4329471A (en) *	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4329470A (en) *	1981-05-04	1982-05-11	Merrell Dow Pharmaceuticals Inc.	5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4367236A (en)	1981-11-04	1983-01-04	Merrell Dow Pharmaceuticals Inc.	Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) *	1981-11-04	1983-10-18	Merrell Dow Pharmaceuticals Inc.	Cardiotonic 4-aroylimidazolidin-2-ones
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
JP2007530566A (ja) *	2004-03-22	2007-11-01	ミオゲンインコーポレイティッド	（ｒ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
EP1737448A1 (en) *	2004-03-22	2007-01-03	Myogen, Inc.	(s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
US8067433B2 (en)	2005-11-09	2011-11-29	Zalicus Inc.	Methods, compositions, and kits for the treatment of ophthalmic disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en)	2007-06-04	2008-12-11	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2627848T3 (es)	2008-06-04	2017-07-31	Synergy Pharmaceuticals Inc.	Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es)	2008-07-16	2017-07-17	Synergy Pharmaceuticals Inc.	Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
MX357121B (es)	2011-03-01	2018-06-27	Synergy Pharmaceuticals Inc Star	Proceso de preparacion de agonistas c de guanilato ciclasa.
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
EP2958577A2 (en)	2013-02-25	2015-12-30	Synergy Pharmaceuticals Inc.	Guanylate cyclase receptor agonists for use in colonic cleansing
US9708367B2 (en)	2013-03-15	2017-07-18	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
EP2968439A2 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
PL3004138T3 (pl)	2013-06-05	2024-07-29	Bausch Health Ireland Limited	Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
CA2920856C (en)	2013-08-09	2026-03-03	Ardelyx, Inc.	Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP2022533251A (ja)	2019-05-21	2022-07-21	アルデリックス，インコーポレイテッド	患者において血清リン酸塩を低下させるための組み合わせ
CN114539157B (zh) *	2022-03-03	2023-12-22	曲靖师范学院	一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2441933A (en) *	1945-07-30	1948-05-18	Hoffmann La Roche	Substituted imidazolones and process of making them

1980
- 1980-06-04 NZ NZ193935A patent/NZ193935A/en unknown
- 1980-06-05 IE IE1162/80A patent/IE50646B1/en not_active IP Right Cessation
- 1980-06-06 AU AU59118/80A patent/AU532783B2/en not_active Expired
- 1980-06-06 IL IL60243A patent/IL60243A/xx unknown
- 1980-06-06 SE SE8004253A patent/SE447107B/sv not_active IP Right Cessation
- 1980-06-09 ES ES492255A patent/ES492255A0/es active Granted
- 1980-06-11 DE DE19803021792 patent/DE3021792A1/de active Granted
- 1980-06-13 AT AT0314280A patent/AT375349B/de not_active IP Right Cessation
- 1980-06-16 PH PH24143A patent/PH18683A/en unknown
- 1980-06-16 CH CH462780A patent/CH646155A5/de not_active IP Right Cessation
- 1980-06-17 CA CA354,197A patent/CA1132554A/en not_active Expired
- 1980-06-17 DK DK259080A patent/DK160269C/da not_active IP Right Cessation
- 1980-06-17 NL NL8003498A patent/NL193752C/nl not_active IP Right Cessation
- 1980-06-17 FR FR8013434A patent/FR2459233A1/fr active Granted
- 1980-06-17 NO NO801796A patent/NO152841C/no unknown
- 1980-06-17 HU HU801506A patent/HU186736B/hu unknown
- 1980-06-17 IT IT48997/80A patent/IT1143922B/it active Protection Beyond IP Right Term
- 1980-06-18 GB GB8019898A patent/GB2055364B/en not_active Expired
1985
- 1985-03-25 SE SE8501452A patent/SE464559B/sv not_active IP Right Cessation
1986
- 1986-08-21 HK HK614/86A patent/HK61486A/xx not_active IP Right Cessation
- 1986-12-30 MY MY709/86A patent/MY8600709A/xx unknown
2000
- 2000-09-04 NL NL300015C patent/NL300015I1/nl unknown

Also Published As

Publication number	Publication date
NO152841C (no)	1985-11-27
IL60243A0 (en)	1980-09-16
GB2055364A (en)	1981-03-04
NL193752B (nl)	2000-05-01
IE50646B1 (en)	1986-06-11
NL300015I1 (nl)	2000-11-01
CA1132554A (en)	1982-09-28
SE447107B (sv)	1986-10-27
MY8600709A (en)	1986-12-31
SE464559B (sv)	1991-05-13
IE801162L (en)	1980-12-18
PH18683A (en)	1985-08-29
NO801796L (no)	1980-12-19
ATA314280A (de)	1983-12-15
DK259080A (da)	1980-12-19
CH646155A5 (de)	1984-11-15
NL193752C (nl)	2000-09-04
DE3021792C2 (sv)	1989-08-10
DK160269B (da)	1991-02-18
SE8501452D0 (sv)	1985-03-25
IT8048997A0 (it)	1980-06-17
NO152841B (no)	1985-08-19
HK61486A (en)	1986-08-29
AT375349B (de)	1984-07-25
ES8105299A1 (es)	1981-06-01
AU532783B2 (en)	1983-10-13
SE8501452L (sv)	1985-03-25
ES492255A0 (es)	1981-06-01
GB2055364B (en)	1983-06-08
NZ193935A (en)	1985-05-31
NL8003498A (nl)	1980-12-22
IT1143922B (it)	1986-10-29
HU186736B (en)	1985-09-30
NL300015I2 (nl)	2000-10-02
DK160269C (da)	1991-07-22
AU5911880A (en)	1981-01-08
FR2459233A1 (fr)	1981-01-09
IL60243A (en)	1987-01-30
DE3021792A1 (de)	1981-01-22
FR2459233B1 (sv)	1983-09-23

Legal Events

Date

Code

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Description

1995-01-31

NAL

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2000-08-14

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