IT8621892A0 - Procedimento per la sintesi di acido tauroursodesossicolico biidrato. - Google Patents
Procedimento per la sintesi di acido tauroursodesossicolico biidrato.Info
- Publication number
- IT8621892A0 IT8621892A0 IT8621892A IT2189286A IT8621892A0 IT 8621892 A0 IT8621892 A0 IT 8621892A0 IT 8621892 A IT8621892 A IT 8621892A IT 2189286 A IT2189286 A IT 2189286A IT 8621892 A0 IT8621892 A0 IT 8621892A0
- Authority
- IT
- Italy
- Prior art keywords
- synthesis
- procedure
- acid dihydrate
- tauroursodeoxycholic acid
- tauroursodeoxycholic
- Prior art date
Links
- BNXLUNVCHFIPFY-GUBAPICVSA-N 2-[[(4r)-4-[(3r,5s,7s,8r,9s,10s,13r,14s,17r)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid;dihydrate Chemical compound O.O.C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]2(C)CC1 BNXLUNVCHFIPFY-GUBAPICVSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21892/86A IT1197330B (it) | 1986-10-03 | 1986-10-03 | Procedimento per la sintesi di acido tauroursodesossicolico biidrato |
| JP62248219A JPS63146895A (ja) | 1986-10-03 | 1987-10-02 | 二水和タウロウルソデオキシコール酸の合成方法 |
| DE19873736918 DE3736918A1 (de) | 1986-10-03 | 1987-10-30 | Verfahren zur herstellung von tauroursodesoxycholsaeure-dihydrat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21892/86A IT1197330B (it) | 1986-10-03 | 1986-10-03 | Procedimento per la sintesi di acido tauroursodesossicolico biidrato |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8621892A0 true IT8621892A0 (it) | 1986-10-03 |
| IT8621892A1 IT8621892A1 (it) | 1988-04-03 |
| IT1197330B IT1197330B (it) | 1988-11-30 |
Family
ID=11188314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT21892/86A IT1197330B (it) | 1986-10-03 | 1986-10-03 | Procedimento per la sintesi di acido tauroursodesossicolico biidrato |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS63146895A (it) |
| DE (1) | DE3736918A1 (it) |
| IT (1) | IT1197330B (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260462A (en) * | 1989-05-30 | 1993-11-09 | Prodotti Chimici E Alimentari S.P.A. | Purification of tauroursodesoxycholic acid dihydrate |
| JPH0749437B2 (ja) * | 1989-06-23 | 1995-05-31 | 東京田辺製薬株式会社 | タウロウルソデオキシコール酸ナトリウムの製造方法 |
| JPH0749438B2 (ja) * | 1990-10-31 | 1995-05-31 | 東京田辺製薬株式会社 | タウリン抱合型胆汁酸の精製方法 |
| IT1270853B (it) * | 1993-05-20 | 1997-05-13 | Sanofi Elf | Procedimento per la preparazione di derivati taurocolanici |
| IT1283182B1 (it) * | 1996-03-04 | 1998-04-16 | Prodotti Chimici Alimentari | Composti coniugati di acidi biliari con tio-taurina e suoi n-alchilderivati |
| EP1985622A1 (en) * | 2007-04-23 | 2008-10-29 | Prodotti Chimici E Alimentari Spa | Process for the preparation of tauroursodesoxycholic acid |
| WO2010005594A1 (en) * | 2008-07-10 | 2010-01-14 | Regenemed Inc. | Compositions and methods of producing ursodeoxycholic acid |
| CN105294809A (zh) * | 2015-12-21 | 2016-02-03 | 杭州和泽医药科技有限公司 | 一种牛磺熊去氧胆酸的制备方法 |
| CN105330715B (zh) * | 2016-01-04 | 2018-07-06 | 杭州和泽医药科技有限公司 | 一种牛磺熊去氧胆酸的制备方法 |
| IT201900005906A1 (it) | 2019-04-16 | 2020-10-16 | Dipharma Francis Srl | Procedimento di preparazione di coniugati di un acido colanico |
-
1986
- 1986-10-03 IT IT21892/86A patent/IT1197330B/it active Protection Beyond IP Right Term
-
1987
- 1987-10-02 JP JP62248219A patent/JPS63146895A/ja active Pending
- 1987-10-30 DE DE19873736918 patent/DE3736918A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63146895A (ja) | 1988-06-18 |
| IT8621892A1 (it) | 1988-04-03 |
| IT1197330B (it) | 1988-11-30 |
| DE3736918A1 (de) | 1989-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ITCP | Complementary protection certificate |
Free format text: CCP 291 |
|
| MEDD | Supplementary protection certificate for pharmaceutical products: granted |
Free format text: CCP 291, 19920513; PRODOTTI CHIMICI E ALIMENTARI SPA |
|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971030 |