IT8920698A0 - Procedimento per la preparazione di acido tauroursodesossicolico biidrato. - Google Patents
Procedimento per la preparazione di acido tauroursodesossicolico biidrato.Info
- Publication number
- IT8920698A0 IT8920698A0 IT8920698A IT2069889A IT8920698A0 IT 8920698 A0 IT8920698 A0 IT 8920698A0 IT 8920698 A IT8920698 A IT 8920698A IT 2069889 A IT2069889 A IT 2069889A IT 8920698 A0 IT8920698 A0 IT 8920698A0
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- preparation
- acid dihydrate
- tauroursodeoxycholic acid
- tauroursodeoxycholic
- Prior art date
Links
- BNXLUNVCHFIPFY-GUBAPICVSA-N 2-[[(4r)-4-[(3r,5s,7s,8r,9s,10s,13r,14s,17r)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid;dihydrate Chemical compound O.O.C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]2(C)CC1 BNXLUNVCHFIPFY-GUBAPICVSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8920698A IT1230796B (it) | 1989-05-30 | 1989-05-30 | Procedimento per la preparazione di acido tauroursodesossicolico biidrato. |
| EP90200513A EP0400695B1 (en) | 1989-05-30 | 1990-03-05 | A process for the preparation of tauroursodesoxycholic acid dihydrate |
| DE69020804T DE69020804D1 (de) | 1989-05-30 | 1990-03-05 | Verfahren zur Herstellung von Tauroursodesoxycholsäure Dihydrat. |
| AT90200513T ATE124954T1 (de) | 1989-05-30 | 1990-03-05 | Verfahren zur herstellung von tauroursodesoxycholsäure dihydrat. |
| JP2118862A JPH0317096A (ja) | 1989-05-30 | 1990-05-10 | タウロウルソデオキシコール酸二水塩の製造方法 |
| US07/913,996 US5260462A (en) | 1989-05-30 | 1992-07-17 | Purification of tauroursodesoxycholic acid dihydrate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8920698A IT1230796B (it) | 1989-05-30 | 1989-05-30 | Procedimento per la preparazione di acido tauroursodesossicolico biidrato. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8920698A0 true IT8920698A0 (it) | 1989-05-30 |
| IT1230796B IT1230796B (it) | 1991-10-29 |
Family
ID=11170729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8920698A IT1230796B (it) | 1989-05-30 | 1989-05-30 | Procedimento per la preparazione di acido tauroursodesossicolico biidrato. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0400695B1 (it) |
| JP (1) | JPH0317096A (it) |
| AT (1) | ATE124954T1 (it) |
| DE (1) | DE69020804D1 (it) |
| IT (1) | IT1230796B (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1247489B (it) * | 1991-04-17 | 1994-12-17 | Prodotti Chimici Alimentari | Acido metiltauroursodesossicolico e suoi derivati terapeuticamente attivi procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono |
| US5616741A (en) * | 1992-08-04 | 1997-04-01 | Erregierre Industria Chimica S.P.A. | Process for the preparation of glycine-conjugated bile acids |
| IT1255486B (it) * | 1992-08-04 | 1995-11-06 | Erregierre Ind Chim | Processo per preparare gli acidi biliari coniugati con la taurina |
| IT1255485B (it) * | 1992-08-04 | 1995-11-06 | Erregierre Ind Chim | Processo per preparare gli acidi biliari coniugati con la glicina e relative composizioni terapeutiche per il trattamento dell'insufficienza epatica |
| IT1270853B (it) * | 1993-05-20 | 1997-05-13 | Sanofi Elf | Procedimento per la preparazione di derivati taurocolanici |
| KR100396113B1 (ko) * | 1996-10-14 | 2003-12-24 | 동아제약 주식회사 | 타우로우르소데옥시콜린산의 정제방법 |
| IT201900005906A1 (it) | 2019-04-16 | 2020-10-16 | Dipharma Francis Srl | Procedimento di preparazione di coniugati di un acido colanico |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59159795A (ja) * | 1983-03-04 | 1984-09-10 | Yakult Honsha Co Ltd | 微生物変換による抱合型ウルソデオキシコ−ル酸の製造方法 |
| IT1167038B (it) * | 1983-11-30 | 1987-05-06 | Prodotti Chimici & Alimentari | Procedimento per la sintesi di acido ursodesossicolico coniugato con la taurina |
| CH674369A5 (it) * | 1986-11-26 | 1990-05-31 | Jago Res Ag |
-
1989
- 1989-05-30 IT IT8920698A patent/IT1230796B/it active
-
1990
- 1990-03-05 DE DE69020804T patent/DE69020804D1/de not_active Expired - Lifetime
- 1990-03-05 AT AT90200513T patent/ATE124954T1/de not_active IP Right Cessation
- 1990-03-05 EP EP90200513A patent/EP0400695B1/en not_active Expired - Lifetime
- 1990-05-10 JP JP2118862A patent/JPH0317096A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0317096A (ja) | 1991-01-25 |
| EP0400695A2 (en) | 1990-12-05 |
| ATE124954T1 (de) | 1995-07-15 |
| DE69020804D1 (de) | 1995-08-17 |
| EP0400695A3 (en) | 1991-07-24 |
| EP0400695B1 (en) | 1995-07-12 |
| IT1230796B (it) | 1991-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970529 |