ITMI941099A0 - Derivati chinolinici - Google Patents

Derivati chinolinici

Info

Publication number
ITMI941099A0
ITMI941099A0 ITMI941099A ITMI941099A ITMI941099A0 IT MI941099 A0 ITMI941099 A0 IT MI941099A0 IT MI941099 A ITMI941099 A IT MI941099A IT MI941099 A ITMI941099 A IT MI941099A IT MI941099 A0 ITMI941099 A0 IT MI941099A0
Authority
IT
Italy
Prior art keywords
quinoline derivatives
quinoline
derivatives
Prior art date
Application number
ITMI941099A
Other languages
English (en)
Inventor
Carlo Farina
Giuseppe Giardina
Mario Grugni
Luca Raveglia
Original Assignee
Smithkline Beecham Farma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Farma filed Critical Smithkline Beecham Farma
Priority to IT94MI001099A priority Critical patent/ITMI941099A1/it
Publication of ITMI941099A0 publication Critical patent/ITMI941099A0/it
Priority to AT98204483T priority patent/ATE273959T1/de
Priority to CZ19963470A priority patent/CZ291476B6/cs
Priority to PL95341889A priority patent/PL186665B1/pl
Priority to BR9507788A priority patent/BR9507788A/pt
Priority to SI9530709T priority patent/SI0940391T1/xx
Priority to NZ287442A priority patent/NZ287442A/en
Priority to EP95920894A priority patent/EP0804419B1/en
Priority to PL95317381A priority patent/PL186075B1/pl
Priority to PCT/EP1995/002000 priority patent/WO1995032948A1/en
Priority to SI9530687T priority patent/SI0804419T1/xx
Priority to HU9603262A priority patent/HU226535B1/hu
Priority to DE69533408T priority patent/DE69533408T2/de
Priority to HU9900343A priority patent/HU9900343D0/hu
Priority to JP50028796A priority patent/JP3664492B2/ja
Priority to NZ329979A priority patent/NZ329979A/xx
Priority to KR1019960706701A priority patent/KR100316571B1/ko
Priority to DK95920894T priority patent/DK0804419T3/da
Priority to AT95920894T priority patent/ATE246677T1/de
Priority to CA002191352A priority patent/CA2191352C/en
Priority to ES98204483T priority patent/ES2227769T3/es
Priority to RU96124804A priority patent/RU2155754C2/ru
Priority to DE69531458T priority patent/DE69531458T2/de
Priority to PT98204483T priority patent/PT940391E/pt
Priority to PT95920894T priority patent/PT804419E/pt
Priority to CN95194338A priority patent/CN1092642C/zh
Priority to CA002257662A priority patent/CA2257662C/en
Priority to SK1514-96A priority patent/SK282721B6/sk
Priority to ES95920894T priority patent/ES2204952T3/es
Priority to AU26164/95A priority patent/AU699319B2/en
Priority to SK47-99A priority patent/SK282722B6/sk
Priority to UA96124918A priority patent/UA51623C2/uk
Priority to RO96-02234A priority patent/RO114445B1/ro
Priority to EP98204483A priority patent/EP0940391B1/en
Priority to DZ950061A priority patent/DZ1889A1/fr
Priority to APAP/P/1995/000745A priority patent/AP578A/en
Priority to MA23898A priority patent/MA23560A1/fr
Priority to IL11384495A priority patent/IL113844A/xx
Priority to MYPI95001381A priority patent/MY129596A/en
Priority to US08/450,437 priority patent/US6608083B1/en
Priority to ZA954269A priority patent/ZA954269B/xx
Priority to US08/450,438 priority patent/US5811553A/en
Priority to TW084105319A priority patent/TW427977B/zh
Priority to TW088121625A priority patent/TW533199B/zh
Priority to SA95160290A priority patent/SA95160290B1/ar
Publication of ITMI941099A1 publication Critical patent/ITMI941099A1/it
Priority to BG101008A priority patent/BG64004B1/bg
Priority to NO965036A priority patent/NO307783B1/no
Priority to MX9605903A priority patent/MX9605903A/es
Priority to FI964712A priority patent/FI115052B/fi
Priority to OA60928A priority patent/OA10592A/en
Priority to HK98103021.0A priority patent/HK1003884B/en
Priority to IL12680698A priority patent/IL126806A0/xx
Priority to CN99100978A priority patent/CN1276211A/zh
Priority to AU12162/99A priority patent/AU1216299A/en
Priority to IL12822099A priority patent/IL128220A0/xx
Priority to FI990268A priority patent/FI119721B/fi
Priority to BG103181A priority patent/BG103181A/bg
Priority to NO991813A priority patent/NO326714B1/no
Priority to JP11172597A priority patent/JP2000026314A/ja
Priority to HK00101401.1A priority patent/HK1024469B/en
Priority to ARP000103117A priority patent/AR037069A2/es
Priority to IL13930100A priority patent/IL139301A0/xx
Priority to US09/867,133 priority patent/US20030236281A1/en
Priority to JP2001326622A priority patent/JP2002179594A/ja
Priority to CN02107941A priority patent/CN1428145A/zh
Priority to JP2004287629A priority patent/JP2005068155A/ja
Priority to US10/999,180 priority patent/US20050096316A1/en
Priority to US11/385,461 priority patent/US7482458B2/en
Priority to JP2006355694A priority patent/JP2007126475A/ja

Links

IT94MI001099A 1994-05-27 1994-05-27 Derivati chinolinici ITMI941099A1 (it)

Priority Applications (69)

Application Number Priority Date Filing Date Title
IT94MI001099A ITMI941099A1 (it) 1994-05-27 1994-05-27 Derivati chinolinici
AT98204483T ATE273959T1 (de) 1994-05-27 1995-05-23 Chinolinderivate als tachykinin nk3 rezeptor antagonisten
CZ19963470A CZ291476B6 (cs) 1994-05-27 1995-05-23 N-(alfa-Ethylbenzyl)-3-hydroxy-2-fenylchinolin-4-karboxamid, farmaceutický prostředek s jeho obsahem a použití
PL95341889A PL186665B1 (pl) 1994-05-27 1995-05-23 Pochodne chinoliny jako antagoniści receptorów NKtachykininy, sposób ich wytwarzania, kompozycja farmaceutyczna zawierająca pochodne chinoliny oraz ich zastosowanie
BR9507788A BR9507788A (pt) 1994-05-27 1995-05-23 Composto ou solvato ou sal do mesmo processo para a preparação do composto composição farmacêutica antagonista do receptor de NK3 uso do composto uso do antagonista do receptor de NG3 e processo para o tratamento e/ou profilaxia de distúrbios pulmonares e distúrbios convulsivos
SI9530709T SI0940391T1 (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin NK3 receptor antagonists
NZ287442A NZ287442A (en) 1994-05-27 1995-05-23 4-substituted quinoline derivatives; medicaments; use as an nk3 receptor antagonist
EP95920894A EP0804419B1 (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin nk 3 receptor antagonists
PL95317381A PL186075B1 (pl) 1994-05-27 1995-05-23 N-(-etylobenzylo)-3-hydroksy-2-fenylochinolino-4-karboksyamid oraz kompozycja farmaceutyczna zawierająca ten związek
PCT/EP1995/002000 WO1995032948A1 (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin nk3 receptor antagonists
SI9530687T SI0804419T1 (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin nk 3 receptor antagonists
HU9603262A HU226535B1 (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin nk3 receptor antagonists, pharmaceutical compositions containing them, and their use
DE69533408T DE69533408T2 (de) 1994-05-27 1995-05-23 Chinolinderivate als Tachykinin NK3 Rezeptor Antagonisten
HU9900343A HU9900343D0 (en) 1994-05-27 1995-05-23 Use of quinoline derivatives having tachycinin nk3 receptor antagonist
JP50028796A JP3664492B2 (ja) 1994-05-27 1995-05-23 タチキニン ｎｋ▲下３▼ 受容体アンタゴニストとしてのキノリン誘導体
NZ329979A NZ329979A (en) 1994-05-27 1995-05-23 Use of NK3 receptor antagonists
KR1019960706701A KR100316571B1 (ko) 1994-05-27 1995-05-23 타키키닌nk3수용체길항제로서퀴놀린유도체
DK95920894T DK0804419T3 (da) 1994-05-27 1995-05-23 Quinolinderivater som tachykinin NK 3-receptor-antagonister
AT95920894T ATE246677T1 (de) 1994-05-27 1995-05-23 Chinolinderivate als tachykinin nk3 rezeptor antagonisten
CA002191352A CA2191352C (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin nk3 receptor antagonists
ES98204483T ES2227769T3 (es) 1994-05-27 1995-05-23 Derivados de quinolina como antagonistas del receptor nk3 de taquiquinina.
RU96124804A RU2155754C2 (ru) 1994-05-27 1995-05-23 Производные хинолина как антагонисты nk3-рецептора тахикинина
DE69531458T DE69531458T2 (de) 1994-05-27 1995-05-23 Chinolinderivate als tachykinin nk3 rezeptor antagonisten
PT98204483T PT940391E (pt) 1994-05-27 1995-05-23 Derivados de quinolina como antagonistas do receptor de taquicinina nk3
PT95920894T PT804419E (pt) 1994-05-27 1995-05-23 Derivados de quinolina como antagonistas do receptor de taquiquinina nk3
CN95194338A CN1092642C (zh) 1994-05-27 1995-05-23 用作速激肽nk3受体拮抗剂的喹啉衍生物
CA002257662A CA2257662C (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin nk3 receptor antagonists
SK1514-96A SK282721B6 (sk) 1994-05-27 1995-05-23 Nepeptidové NK3 antagonistické látky, spôsob ich výroby, farmaceutické prostriedky s ich obsahom a ich použitie
ES95920894T ES2204952T3 (es) 1994-05-27 1995-05-23 Derivados de la quinoleina utiles como antagonistas del receptor nk3 de la taquiquinina.
AU26164/95A AU699319B2 (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin nk3 receptor antagonists
SK47-99A SK282722B6 (sk) 1994-05-27 1995-05-23 N-(alfa-Etylbenzyl)-3-hydroxy-2-fenylchinolín-4-karboxamid, farmaceutický prípravok s jeho obsahom a jeho použitie
UA96124918A UA51623C2 (uk) 1994-05-27 1995-05-23 ПОХІДНІ ХІНОЛІНУ ЯК АНТАГОНІСТИ NK<sub>3</sub> РЕЦЕПТОРА, СПОСІБ ЇХ ОДЕРЖАННЯ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ НА ЇХ ОСНОВІ ТА СПОСІБ ЛІКУВАННЯ ЗАХВОРЮВАНЬ
RO96-02234A RO114445B1 (ro) 1994-05-27 1995-05-23 Derivaţi de chinolină antagonişti ai receptorului nk3 tachichinină,procedeu de preparare,compoziţii farmaceutice pe baza acestora şi metodă de tratament
EP98204483A EP0940391B1 (en) 1994-05-27 1995-05-23 Quinoline derivatives as tachykinin NK3 receptor antagonists
DZ950061A DZ1889A1 (fr) 1994-05-27 1995-05-24 Dérivés de quinoléine nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
APAP/P/1995/000745A AP578A (en) 1994-05-27 1995-05-24 Quinoline derivatives.
MA23898A MA23560A1 (fr) 1994-05-27 1995-05-25 Procede de preparation de derives de quinoline et utilisation de ces derives dans la production des medicaments
IL11384495A IL113844A (en) 1994-05-27 1995-05-25 N-(alpha-ETHYLBENZYL)-3-HYDROXY-2-PHENYLQUINOLINE-4-CARBOXAMIDE AND ITS USE IN THE PREPARATION OF MEDICAMENTS
MYPI95001381A MY129596A (en) 1994-05-27 1995-05-25 Quinoline derivatives as tachykinin nk3 receptor antagonists
US08/450,437 US6608083B1 (en) 1994-05-27 1995-05-25 Quinoline derivatives(2)
ZA954269A ZA954269B (en) 1994-05-27 1995-05-25 Quinoline derivatives
US08/450,438 US5811553A (en) 1994-05-27 1995-05-25 Quinoline derivatives(2)
TW084105319A TW427977B (en) 1994-05-27 1995-05-26 Quinoline derivatives
TW088121625A TW533199B (en) 1994-05-27 1995-05-26 Quinoline derivatives
SA95160290A SA95160290B1 (ar) 1994-05-27 1995-10-03 مشتقات كينولين (2)
BG101008A BG64004B1 (bg) 1994-05-27 1996-11-25 Производни на хинолина като тахикинин nк долу 3 рецепторни антагонисти
NO965036A NO307783B1 (no) 1994-05-27 1996-11-26 Kinolinderivater som tachykinin NK3 reseptor-antagonister, farmasøytiske preparater inneholdende dem og anvendelse av slike derivater
MX9605903A MX9605903A (es) 1994-05-27 1996-11-26 Derivados de quinolina como antagonistas del receptor nk3 de taquicinina.
FI964712A FI115052B (fi) 1994-05-27 1996-11-26 Kinoliinijohdannaisia takykiniini-NK3-reseptoriantagonisteina
OA60928A OA10592A (en) 1994-05-27 1996-11-27 Quinoline derivatives as tachykinin nk3 receptor antagonists
HK98103021.0A HK1003884B (en) 1994-05-27 1998-04-09 Quinoline derivatives as tachykinin nk3 receptor antagonists
IL12680698A IL126806A0 (en) 1994-05-27 1998-10-29 Quinoline derivatives
CN99100978A CN1276211A (zh) 1994-05-27 1999-01-15 非肽类nk3－拮抗剂的制药用途
AU12162/99A AU1216299A (en) 1994-05-27 1999-01-19 Quinoline derivatives as tachykinin NK3 receptor antagonists
IL12822099A IL128220A0 (en) 1994-05-27 1999-01-25 Quinoline derivatives and uses thereof
FI990268A FI119721B (fi) 1994-05-27 1999-02-10 Ei-peptidi-NK-antagonistin käyttö ihosairauksien ja kutinan hoitoon tarkoitettujen lääkkeiden valmistukseen
BG103181A BG103181A (bg) 1994-05-27 1999-02-16 Използване на непептидни nk3 антагонисти за лечение на кожни заболявания и сърбеж
NO991813A NO326714B1 (no) 1994-05-27 1999-04-16 Anvendelse av kinolinderivater for fremstilling av farmasøytisk preparat for behandling av hudsykdommer og kløe.
JP11172597A JP2000026314A (ja) 1994-05-27 1999-06-18 タチキニンｎｋ３受容体アンタゴニストとしてのキノリン誘導体
HK00101401.1A HK1024469B (en) 1994-05-27 2000-03-06 Quinoline derivatives as tachykinin nk3 receptor antagonists
ARP000103117A AR037069A2 (es) 1994-05-27 2000-06-22 Un nuevo derivado de la quinolin-4-carboxamida, la n-(alfa-etilbencil)-3-hidroxi-2-fenilquinolin-4-carboxamida, una composicion farmaceutica que lo contiene y su uso para la fabricacion de medicamentos
IL13930100A IL139301A0 (en) 1994-05-27 2000-10-26 Quinoline derivatives
US09/867,133 US20030236281A1 (en) 1994-05-27 2001-05-29 Quinoline derivatives(2)
JP2001326622A JP2002179594A (ja) 1994-05-27 2001-10-24 タチキニンｎｋ３受容体アンタゴニストとしてのキノリン誘導体
CN02107941A CN1428145A (zh) 1994-05-27 2002-03-18 用作速激肽nk3受体拮抗剂的喹啉衍生物
JP2004287629A JP2005068155A (ja) 1994-05-27 2004-09-30 タチキニンｎｋ３受容体アンタゴニストとしてのキノリン誘導体
US10/999,180 US20050096316A1 (en) 1994-05-27 2004-11-29 Quinoline derivatives(2)
US11/385,461 US7482458B2 (en) 1994-05-27 2006-03-21 Quinoline derivatives
JP2006355694A JP2007126475A (ja) 1994-05-27 2006-12-28 タチキニンｎｋ３受容体アンタゴニストとしてのキノリン誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT94MI001099A ITMI941099A1 (it) 1994-05-27 1994-05-27 Derivati chinolinici

Publications (2)

Publication Number Publication Date
ITMI941099A0 true ITMI941099A0 (it) 1994-05-27
ITMI941099A1 ITMI941099A1 (it) 1995-11-27

Family

ID=11369006

Family Applications (1)

Application Number Title Priority Date Filing Date
IT94MI001099A ITMI941099A1 (it) 1994-05-27 1994-05-27 Derivati chinolinici

Country Status (3)

Country Link
IT (1) ITMI941099A1 (it)
RU (1) RU2155754C2 (it)
ZA (1) ZA954269B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS56037B1 (sr) 2004-06-24 2017-09-29 Vertex Pharma Modulatori atp-vezujućih kasetnih transportera
EP3219705B1 (en) 2005-12-28 2020-03-11 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions of the amorphous form of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
CN102224141B (zh) * 2008-10-23 2014-10-08 沃泰克斯药物股份有限公司 N-(4-(7-氮杂双环[2.2.1]庚-7-基)-2-(三氟甲基)苯基)-4-氧代-5-(三氟甲基)-1,4-二氢喹啉-3-甲酰胺的固体形式
PL2408750T3 (pl) 2009-03-20 2016-02-29 Vertex Pharma Sposób otrzymywania modulatorów błonowego regulatora przewodnictwa swoistego dla mukowiscydozy
CN102666546B (zh) * 2009-10-23 2015-09-09 沃泰克斯药物股份有限公司 N-(4-(7-氮杂双环[2.2.1]庚-7-基)-2-(三氟甲基)苯基)-4-氧代-5-(三氟甲基)-1,4-二氢喹啉-3-甲酰胺的固体形式
JP2015511583A (ja) 2012-02-27 2015-04-20 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ 薬学的組成物およびその投与
CN107250113B (zh) 2014-10-07 2019-03-29 弗特克斯药品有限公司 囊性纤维化跨膜传导调节蛋白的调节剂的共晶

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2538388B1 (fr) * 1982-12-24 1985-06-21 Pharmuka Lab Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments
SU1450741A3 (ru) * 1984-09-28 1989-01-07 Ниппон Кемифар Ко,Лтд (Фирма) Способ получени производных хинальдинамида или их кислотно-аддитивных солей

Also Published As

Publication number Publication date
ITMI941099A1 (it) 1995-11-27
ZA954269B (en) 1996-05-14
RU2155754C2 (ru) 2000-09-10

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