ITRM20080182A1 - Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma. - Google Patents

Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma.

Info

Publication number
ITRM20080182A1
ITRM20080182A1 IT000182A ITRM20080182A ITRM20080182A1 IT RM20080182 A1 ITRM20080182 A1 IT RM20080182A1 IT 000182 A IT000182 A IT 000182A IT RM20080182 A ITRM20080182 A IT RM20080182A IT RM20080182 A1 ITRM20080182 A1 IT RM20080182A1
Authority
IT
Italy
Prior art keywords
dorzolamide
latanoprost
glaucoma
preparation based
ophthalmic preparation
Prior art date
Application number
IT000182A
Other languages
English (en)
Inventor
Danilo Aleo
Sergio Mangiafico
Maria Grazia Antonietta Saita
Original Assignee
Medivis S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivis S R L filed Critical Medivis S R L
Priority to IT000182A priority Critical patent/ITRM20080182A1/it
Priority to PCT/IB2008/003381 priority patent/WO2009125246A1/en
Priority to JP2011503508A priority patent/JP2011516537A/ja
Priority to EP08873876.0A priority patent/EP2280689B1/en
Priority to AU2008354558A priority patent/AU2008354558B2/en
Priority to US12/936,640 priority patent/US8680078B2/en
Priority to CN2012105962691A priority patent/CN103181919A/zh
Priority to CN2008801296744A priority patent/CN102046149B/zh
Priority to EP13193754.2A priority patent/EP2710999A1/en
Publication of ITRM20080182A1 publication Critical patent/ITRM20080182A1/it
Priority to US14/180,254 priority patent/US20140163030A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT000182A 2008-04-07 2008-04-07 Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma. ITRM20080182A1 (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT000182A ITRM20080182A1 (it) 2008-04-07 2008-04-07 Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma.
PCT/IB2008/003381 WO2009125246A1 (en) 2008-04-07 2008-11-07 Stable ophthalmic formulations
JP2011503508A JP2011516537A (ja) 2008-04-07 2008-11-07 安定性のある眼科用の製剤
EP08873876.0A EP2280689B1 (en) 2008-04-07 2008-11-07 Stable ophthalmic formulations
AU2008354558A AU2008354558B2 (en) 2008-04-07 2008-11-07 Stable ophthalmic formulations
US12/936,640 US8680078B2 (en) 2008-04-07 2008-11-07 Stable ophthalmic formulations
CN2012105962691A CN103181919A (zh) 2008-04-07 2008-11-07 稳定的眼药制剂
CN2008801296744A CN102046149B (zh) 2008-04-07 2008-11-07 稳定的眼药制剂
EP13193754.2A EP2710999A1 (en) 2008-04-07 2008-11-07 Stable ophthalmic formulations
US14/180,254 US20140163030A1 (en) 2008-04-07 2014-02-13 Stable ophthalmic formulations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000182A ITRM20080182A1 (it) 2008-04-07 2008-04-07 Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma.

Publications (1)

Publication Number Publication Date
ITRM20080182A1 true ITRM20080182A1 (it) 2009-10-08

Family

ID=40297206

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000182A ITRM20080182A1 (it) 2008-04-07 2008-04-07 Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma.

Country Status (7)

Country Link
US (2) US8680078B2 (it)
EP (2) EP2280689B1 (it)
JP (1) JP2011516537A (it)
CN (2) CN103181919A (it)
AU (1) AU2008354558B2 (it)
IT (1) ITRM20080182A1 (it)
WO (1) WO2009125246A1 (it)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20080182A1 (it) 2008-04-07 2009-10-08 Medivis S R L Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma.
US10463677B2 (en) * 2008-11-07 2019-11-05 Cydex Pharmaceuticals, Inc. Composition containing sulfoalkyl ether cyclodextrin and latanoprost
WO2010089355A1 (en) * 2009-02-04 2010-08-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Taurine or taurine-like substances for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
DE102009021372A1 (de) * 2009-05-14 2010-11-18 Ursapharm Arzneimittel Gmbh Phosphatfreie pharmazeutische Zusammensetzung zur Glaukombehandlung
MX2013000855A (es) 2010-07-22 2013-02-27 Merz Pharma Gmbh & Co Kgaa Composicion farmaceutica que contiene derivado de triptofano.
WO2012021107A2 (en) 2010-08-12 2012-02-16 Nanyang Technological University A liposomal formulation for ocular drug delivery
CN103079595B (zh) * 2010-08-27 2015-11-25 若素制药株式会社 滴眼用水性组合物
CN102961748A (zh) * 2011-08-30 2013-03-13 香港理工大学 使用缝隙连接阻断剂降低眼压的方法
EP2567689A1 (en) * 2011-09-12 2013-03-13 Visiotact Pharma Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid
WO2013087808A1 (en) 2011-12-15 2013-06-20 Merz Pharma Gmbh & Co. Kgaa Pharmaceutical composition comprising a pyrazolopyrimidme and cyclodextrin
EP3827823A1 (en) * 2012-12-19 2021-06-02 Novartis AG Lfa-1 inhibitor formulations
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
WO2016172712A2 (en) * 2015-04-23 2016-10-27 Sydnexis, Inc. Ophthalmic composition
US9421199B2 (en) 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
WO2016072939A1 (en) * 2014-11-07 2016-05-12 National University Of Singapore Formulations comprising antimicrobial agents with hydrophobic moieties and uses thereof
WO2016136651A1 (ja) * 2015-02-23 2016-09-01 参天製薬株式会社 ドルゾラミドを含有する防腐剤
CN104740205A (zh) * 2015-03-14 2015-07-01 焦永法 一种治疗外伤性前房积血的中药制剂
US11052094B2 (en) 2015-05-29 2021-07-06 Sydnexis, Inc. D2O stabilized pharmaceutical formulations
PL3193832T3 (pl) * 2015-06-17 2019-12-31 Al.Chi.Mi.A. S.R.L. Lepkosprężysty preparat do stosowania w metodach chirurgicznych w chirurgii ocznej
JP6050454B1 (ja) * 2015-09-28 2016-12-21 参天製薬株式会社 水性医薬組成物
CN106967515A (zh) * 2016-04-19 2017-07-21 明基材料股份有限公司 隐形眼镜保养液
GR1009040B (el) * 2016-04-19 2017-05-19 Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων Φαρμακευτικο οφθαλμικο σκευασμα ελευθερο συντηρητικου
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
US12303527B2 (en) 2018-04-18 2025-05-20 i.com medical GmbH High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease
US12268706B2 (en) 2019-01-31 2025-04-08 i.com medical GmbH Hyaluronic acid for relief of idiopathic ocular pain
CN115350148A (zh) 2019-02-06 2022-11-18 特清公司 用于从包含络合剂的眼用制剂中去除防腐剂的系统和方法
US11071724B2 (en) 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
ES3008008T3 (en) * 2020-06-21 2025-03-21 I Com Medical Gmbh Use of high molecular weight hyaluronic acid as ocular transporting vehicle
EP4309644A1 (en) * 2022-07-22 2024-01-24 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Preservative-free ophthalmic composition comprising an antiglaucoma agent
MX2023009955A (es) * 2023-08-24 2025-03-07 Sophia Holdings S A De C V Composiciones farmaceuticas oftalmicas que contienen dorzolamida, metodos para su preparacion y uso de las mismas.
JP2026519325A (ja) * 2024-05-13 2026-06-16 ヒューオンス カンパニー， リミテッド 炭酸脱水酵素阻害剤及びチモロールを含有する透明複合点眼剤、並びにその製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494901A (en) * 1993-01-05 1996-02-27 Javitt; Jonathan C. Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent
EP1058546A4 (en) * 1998-03-06 2004-07-28 Univ Texas COMPILATIONS AND METHODS FOR THE TREATMENT OF MACULA DISEASES
US20030018079A1 (en) * 2000-11-13 2003-01-23 Richardson Helene Treatment
JP4314429B2 (ja) * 2002-08-23 2009-08-19 参天製薬株式会社 ラタノプロストを有効成分とする安定な点眼液
ES2320770T3 (es) * 2004-05-26 2009-05-28 Arturo Jimenez Bayardo Metodo de preparacion de una solucion oftalmica de latanoprost y la solucion asi producida.
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
ITRM20080182A1 (it) 2008-04-07 2009-10-08 Medivis S R L Preparato oftalmico a base di dorzolamide e latanoprost per il trattamento topico del glaucoma.

Also Published As

Publication number Publication date
US20110028477A1 (en) 2011-02-03
EP2710999A1 (en) 2014-03-26
JP2011516537A (ja) 2011-05-26
AU2008354558B2 (en) 2013-07-25
US8680078B2 (en) 2014-03-25
WO2009125246A1 (en) 2009-10-15
CN103181919A (zh) 2013-07-03
AU2008354558A1 (en) 2009-10-15
CN102046149A (zh) 2011-05-04
CN102046149B (zh) 2013-01-30
EP2280689B1 (en) 2014-07-23
US20140163030A1 (en) 2014-06-12
EP2280689A1 (en) 2011-02-09

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