ITTO910907A0 - Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo. - Google Patents
Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo.Info
- Publication number
- ITTO910907A0 ITTO910907A0 IT91TO907A ITTO910907A ITTO910907A0 IT TO910907 A0 ITTO910907 A0 IT TO910907A0 IT 91TO907 A IT91TO907 A IT 91TO907A IT TO910907 A ITTO910907 A IT TO910907A IT TO910907 A0 ITTO910907 A0 IT TO910907A0
- Authority
- IT
- Italy
- Prior art keywords
- estradiol
- acrylic
- based adhesive
- copolymer matrix
- matrix preparation
- Prior art date
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title 1
- 239000000853 adhesive Substances 0.000 title 1
- 230000001070 adhesive effect Effects 0.000 title 1
- 229920001577 copolymer Polymers 0.000 title 1
- 229960005309 estradiol Drugs 0.000 title 1
- 229930182833 estradiol Natural products 0.000 title 1
- 239000011159 matrix material Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITTO910907A IT1253265B (it) | 1991-11-25 | 1991-11-25 | Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo. |
| JP5509788A JPH07501335A (ja) | 1991-11-25 | 1992-11-24 | エストラジオール経皮投与用のアクリル系接着性共重合マトリックスを備えた新規な調合物 |
| DK92923782.4T DK0614356T3 (da) | 1991-11-25 | 1992-11-24 | Transdermalt estradiolafgivelsessystem |
| ES92923782T ES2078066T3 (es) | 1991-11-25 | 1992-11-24 | Sistema de suministro transdermico de estradiol. |
| AU29451/92A AU666151B2 (en) | 1991-11-25 | 1992-11-24 | Transdermal estradiol delivery system |
| DE69205010T DE69205010T2 (de) | 1991-11-25 | 1992-11-24 | Transdermales estradiol als therapeutisches system. |
| US08/244,132 US6156335A (en) | 1991-11-25 | 1992-11-24 | Preparation with an acrylic-based, adhesive copolymeric matrix for the transdermal delivery of estradiol |
| EP92923782A EP0614356B1 (en) | 1991-11-25 | 1992-11-24 | Transdermal estradiol delivery system |
| PCT/EP1992/002704 WO1993010772A1 (en) | 1991-11-25 | 1992-11-24 | Transdermal estradiol delivery system |
| AT92923782T ATE128029T1 (de) | 1991-11-25 | 1992-11-24 | Transdermales estradiol als therapeutisches system. |
| CA002124209A CA2124209A1 (en) | 1991-11-25 | 1992-11-24 | A new preparation with an acrylic-based adhesive copolymeric matrix for the transdermal delivery of estradiol |
| GR950403422T GR3018303T3 (en) | 1991-11-25 | 1995-12-05 | Transdermal estradiol delivery system. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITTO910907A IT1253265B (it) | 1991-11-25 | 1991-11-25 | Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITTO910907A0 true ITTO910907A0 (it) | 1991-11-25 |
| ITTO910907A1 ITTO910907A1 (it) | 1993-05-25 |
| IT1253265B IT1253265B (it) | 1995-07-14 |
Family
ID=11409742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITTO910907A IT1253265B (it) | 1991-11-25 | 1991-11-25 | Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6156335A (it) |
| EP (1) | EP0614356B1 (it) |
| JP (1) | JPH07501335A (it) |
| AT (1) | ATE128029T1 (it) |
| AU (1) | AU666151B2 (it) |
| CA (1) | CA2124209A1 (it) |
| DE (1) | DE69205010T2 (it) |
| DK (1) | DK0614356T3 (it) |
| ES (1) | ES2078066T3 (it) |
| GR (1) | GR3018303T3 (it) |
| IT (1) | IT1253265B (it) |
| WO (1) | WO1993010772A1 (it) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5554381A (en) * | 1993-08-09 | 1996-09-10 | Cygnus, Inc. | Low flux matrix system for delivering potent drugs transdermally |
| DE4333595A1 (de) * | 1993-10-01 | 1995-04-06 | Labtec Gmbh | Transdermales therapeutisches System zur Applikation von Arzneimitteln auf die Haut |
| GR1002079B (en) * | 1994-07-26 | 1995-12-05 | Lavipharm A E | System of a special structure and composition for the rapid transdermal administration of oestrogens. |
| DE19526864A1 (de) * | 1995-07-22 | 1997-01-23 | Labtec Gmbh | Hormonpflaster |
| DE19600347A1 (de) * | 1996-01-08 | 1997-07-10 | Lohmann Therapie Syst Lts | Hauthaftende pharmazeutische Zubereitung, insbesondere TTS zur Abgabe von 17-beta-Estradiol an den menschlichen Organismus |
| US6623763B2 (en) | 1996-01-08 | 2003-09-23 | Lts Lohmann Therape-System Ag | Pharmaceutical preparation adhering to the skin, in particular a transdermal therapeutic system for the release of 17-β-estradiol to the human organism |
| DE19830649C2 (de) * | 1998-07-09 | 2003-04-10 | Lohmann Therapie Syst Lts | Topisches Pflaster mit nichtsteroidalen Antirheumatika mit Säuregruppe |
| GB0019745D0 (en) * | 2000-08-10 | 2000-09-27 | Univ Surrey | Gene expression element |
| US20020106402A1 (en) * | 2000-12-05 | 2002-08-08 | Hartwig Rod Lawson | Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use |
| DE10141652B4 (de) * | 2001-08-24 | 2011-04-07 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
| US6927267B1 (en) | 2002-03-07 | 2005-08-09 | Basf Ag | High solids dispersion for wide temperature, pressure sensitive adhesive applications |
| DE10229733A1 (de) * | 2002-07-02 | 2004-01-22 | Basf Ag | Haftklebstoffe für Träger aus Weich-PVC |
| US8124122B2 (en) | 2002-08-09 | 2012-02-28 | Teikoku Seiyaku Co., Ltd. | Female hormone-containing patch |
| WO2006037922A1 (fr) * | 2004-10-04 | 2006-04-13 | L'oreal | Composition cosmetique et/ou dermatologique pour peaux sensibles |
| FR2889057B1 (fr) * | 2005-08-01 | 2008-07-18 | Oreal | Composition cosmetique et/ou dermatologique pour la prevention et/ou le traitement des peaux sensibles ou seches |
| US7754256B2 (en) * | 2007-03-07 | 2010-07-13 | Stan Dennison | Nutritional composition |
| US20080226698A1 (en) * | 2007-03-16 | 2008-09-18 | Mylan Technologies, Inc. | Amorphous drug transdermal systems, manufacturing methods, and stabilization |
| FR2919501B1 (fr) * | 2007-08-02 | 2010-12-31 | Oreal | Utilisation d'hesperidine ou de l'un de ses derives pour la prevention et/ou le traitement des peaux relachees |
| FR2920304B1 (fr) | 2007-09-04 | 2010-06-25 | Oreal | Utilisation cosmetique de lysat bifidobacterium species pour le traitement de la secheresse. |
| WO2009031106A2 (en) * | 2007-09-04 | 2009-03-12 | L'oreal | Use of a combination of hesperidin and of a microorganism for influencing the barrier function of the skin |
| DE102008013701A1 (de) | 2008-03-11 | 2009-09-17 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit stabilisierter Membran |
| WO2009158120A2 (en) * | 2008-05-30 | 2009-12-30 | Mylan Laboratories Inc. | Stabilized transdermal drug delivery system |
| US8231906B2 (en) | 2008-07-10 | 2012-07-31 | Noven Pharmaceuticals, Inc. | Transdermal estrogen device and delivery |
| EP2349230A2 (en) | 2008-10-06 | 2011-08-03 | Mylan Technologies, Inc. | Amorphous rotigotine transdermal system |
| DE102008059054A1 (de) | 2008-11-26 | 2010-05-27 | Otto Bock Pur Life Science Gmbh | Polyurethanpflaster für die transdermale Applikation von Wirkstoffen und Verfahren zu dessen Herstellung |
| WO2011009800A1 (en) * | 2009-07-21 | 2011-01-27 | Basf Se | Film-to-film laminate, made by using an aqueous polymer dispersion as adhesive agent |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4906475A (en) * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
| WO1989007951A1 (en) * | 1988-02-26 | 1989-09-08 | Riker Laboratories, Incorporated | Transdermal estradiol delivery system |
| US4994267A (en) * | 1988-03-04 | 1991-02-19 | Noven Pharmaceuticals, Inc. | Transdermal acrylic multipolymer drug delivery system |
| EP0484543B1 (en) * | 1990-04-24 | 1995-12-13 | Teijin Limited | Plaster |
-
1991
- 1991-11-25 IT ITTO910907A patent/IT1253265B/it active IP Right Grant
-
1992
- 1992-11-24 DK DK92923782.4T patent/DK0614356T3/da active
- 1992-11-24 US US08/244,132 patent/US6156335A/en not_active Expired - Fee Related
- 1992-11-24 CA CA002124209A patent/CA2124209A1/en not_active Abandoned
- 1992-11-24 AU AU29451/92A patent/AU666151B2/en not_active Ceased
- 1992-11-24 WO PCT/EP1992/002704 patent/WO1993010772A1/en not_active Ceased
- 1992-11-24 AT AT92923782T patent/ATE128029T1/de not_active IP Right Cessation
- 1992-11-24 EP EP92923782A patent/EP0614356B1/en not_active Expired - Lifetime
- 1992-11-24 ES ES92923782T patent/ES2078066T3/es not_active Expired - Lifetime
- 1992-11-24 JP JP5509788A patent/JPH07501335A/ja active Pending
- 1992-11-24 DE DE69205010T patent/DE69205010T2/de not_active Expired - Lifetime
-
1995
- 1995-12-05 GR GR950403422T patent/GR3018303T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07501335A (ja) | 1995-02-09 |
| CA2124209A1 (en) | 1993-06-10 |
| DE69205010T2 (de) | 1996-02-22 |
| DK0614356T3 (da) | 1995-11-13 |
| ATE128029T1 (de) | 1995-10-15 |
| US6156335A (en) | 2000-12-05 |
| AU666151B2 (en) | 1996-02-01 |
| EP0614356B1 (en) | 1995-09-20 |
| ITTO910907A1 (it) | 1993-05-25 |
| EP0614356A1 (en) | 1994-09-14 |
| IT1253265B (it) | 1995-07-14 |
| ES2078066T3 (es) | 1995-12-01 |
| AU2945192A (en) | 1993-06-28 |
| DE69205010D1 (en) | 1995-10-26 |
| GR3018303T3 (en) | 1996-03-31 |
| WO1993010772A1 (en) | 1993-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971129 |