JOP20200030A1 - مركب خماسي الحلقة - Google Patents
مركب خماسي الحلقةInfo
- Publication number
- JOP20200030A1 JOP20200030A1 JOP/2020/0030A JOP20200030A JOP20200030A1 JO P20200030 A1 JOP20200030 A1 JO P20200030A1 JO P20200030 A JOP20200030 A JO P20200030A JO P20200030 A1 JOP20200030 A1 JO P20200030A1
- Authority
- JO
- Jordan
- Prior art keywords
- pentacyclic compound
- pentacyclic
- compound
- formulas
- pharmaceutically acceptable
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
يتعلق الاختراع الحالي بمركبات ممثلة بالصيغ (I) إلى (VI) أو أملاح مقبولة صيدلانياً منها:
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017172169 | 2017-09-07 | ||
| PCT/JP2018/032797 WO2019049869A1 (ja) | 2017-09-07 | 2018-09-05 | 五環式化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JOP20200030A1 true JOP20200030A1 (ar) | 2020-02-12 |
| JOP20200030B1 JOP20200030B1 (ar) | 2025-10-01 |
Family
ID=65517037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOJO/P/2020/0030A JOP20200030B1 (ar) | 2017-09-07 | 2018-09-05 | مركب خماسي الحلقة |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US10239889B1 (ar) |
| EP (1) | EP3680243B1 (ar) |
| JP (1) | JP6557441B1 (ar) |
| KR (1) | KR102307738B1 (ar) |
| CN (1) | CN111051316B (ar) |
| AR (1) | AR112788A1 (ar) |
| AU (1) | AU2018330578B2 (ar) |
| CA (1) | CA3072740A1 (ar) |
| CL (1) | CL2020000376A1 (ar) |
| CO (1) | CO2020001471A2 (ar) |
| CY (1) | CY1125355T1 (ar) |
| DK (1) | DK3680243T3 (ar) |
| ES (1) | ES2903172T3 (ar) |
| HR (1) | HRP20220019T1 (ar) |
| HU (1) | HUE056791T2 (ar) |
| IL (1) | IL272652B (ar) |
| JO (1) | JOP20200030B1 (ar) |
| LT (1) | LT3680243T (ar) |
| MA (1) | MA50093B1 (ar) |
| MD (1) | MD3680243T2 (ar) |
| MX (1) | MX2020001786A (ar) |
| PE (1) | PE20200860A1 (ar) |
| PH (1) | PH12020500341A1 (ar) |
| PL (1) | PL3680243T3 (ar) |
| PT (1) | PT3680243T (ar) |
| RS (1) | RS62796B1 (ar) |
| RU (1) | RU2754557C1 (ar) |
| SG (1) | SG11202001240XA (ar) |
| SI (1) | SI3680243T1 (ar) |
| SM (1) | SMT202200004T1 (ar) |
| TW (1) | TWI707859B (ar) |
| UA (1) | UA125940C2 (ar) |
| WO (1) | WO2019049869A1 (ar) |
| ZA (2) | ZA202000970B (ar) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3678666B1 (en) | 2017-09-07 | 2025-07-09 | Augusta University Research Institute, Inc. | Specific akt3 activator and uses thereof |
| CN109467538A (zh) | 2017-09-07 | 2019-03-15 | 和记黄埔医药（上海）有限公司 | 环烯烃取代的杂芳环类化合物及其用途 |
| MX2021009685A (es) * | 2019-03-05 | 2021-09-10 | Eisai R&D Man Co Ltd | Compuesto heterociclo pentaciclico. |
| TWI870286B (zh) * | 2019-03-05 | 2025-01-11 | 日商衛材R&D企管股份有限公司 | 五環化合物之鹽及其等之結晶 |
| US20230101747A1 (en) * | 2019-12-06 | 2023-03-30 | Schrödinger, Inc. | Cyclic compounds and methods of using same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4187306A (en) * | 1977-07-26 | 1980-02-05 | Bayer Aktiengesellschaft | Benzodiazepine-diones, a process for their production and their use as medicaments |
| DD258234A1 (de) * | 1987-03-05 | 1988-07-13 | Univ Leipzig | Verfahren zur herstellung von pyrido/3',2':4,5/thieno/2,3-e/imidazo-/1,2-c/pyrimidinen sowie strukturanaloger -pyrimido/1,2-c/pyrimidine bzw. -1,3-diazepino/1,2-c/pyrimidine |
| RU2117670C1 (ru) * | 1988-10-31 | 1998-08-20 | Эйсай Ко., Лтд. | Производные триазоло[1,4]диазепина и способы их получения |
| TW197442B (ar) * | 1990-02-08 | 1993-01-01 | Pfizer | |
| KR100203456B1 (ko) | 1995-06-20 | 1999-06-15 | 한승수 | 디하이드로에보디아민-에이치씨1를 유효성분으로 함유하는 알츠하이머병에 의한 치매 치료제 |
| FR2779652B1 (fr) * | 1998-06-15 | 2001-06-08 | Sod Conseils Rech Applic | Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique |
| RU2007114763A (ru) * | 2004-10-20 | 2008-11-27 | Ф.Хоффманн-Ля Рош Аг (Ch) | Галогенозамещенные производные бензодиазепинов |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
-
2018
- 2018-09-05 TW TW107131095A patent/TWI707859B/zh active
- 2018-09-05 MA MA50093A patent/MA50093B1/fr unknown
- 2018-09-05 PT PT188534150T patent/PT3680243T/pt unknown
- 2018-09-05 DK DK18853415.0T patent/DK3680243T3/da active
- 2018-09-05 MD MDE20200725T patent/MD3680243T2/ro unknown
- 2018-09-05 AU AU2018330578A patent/AU2018330578B2/en active Active
- 2018-09-05 LT LTEPPCT/JP2018/032797T patent/LT3680243T/lt unknown
- 2018-09-05 PL PL18853415T patent/PL3680243T3/pl unknown
- 2018-09-05 JP JP2019516726A patent/JP6557441B1/ja active Active
- 2018-09-05 EP EP18853415.0A patent/EP3680243B1/en active Active
- 2018-09-05 MX MX2020001786A patent/MX2020001786A/es unknown
- 2018-09-05 JO JOJO/P/2020/0030A patent/JOP20200030B1/ar active
- 2018-09-05 US US16/122,116 patent/US10239889B1/en active Active
- 2018-09-05 PE PE2020000228A patent/PE20200860A1/es unknown
- 2018-09-05 IL IL272652A patent/IL272652B/en unknown
- 2018-09-05 RU RU2020106798A patent/RU2754557C1/ru active
- 2018-09-05 CA CA3072740A patent/CA3072740A1/en active Pending
- 2018-09-05 SI SI201830467T patent/SI3680243T1/sl unknown
- 2018-09-05 ES ES18853415T patent/ES2903172T3/es active Active
- 2018-09-05 AR ARP180102517A patent/AR112788A1/es active IP Right Grant
- 2018-09-05 WO PCT/JP2018/032797 patent/WO2019049869A1/ja not_active Ceased
- 2018-09-05 RS RS20220015A patent/RS62796B1/sr unknown
- 2018-09-05 UA UAA202000934A patent/UA125940C2/uk unknown
- 2018-09-05 SG SG11202001240XA patent/SG11202001240XA/en unknown
- 2018-09-05 HU HUE18853415A patent/HUE056791T2/hu unknown
- 2018-09-05 KR KR1020207004232A patent/KR102307738B1/ko active Active
- 2018-09-05 SM SM20220004T patent/SMT202200004T1/it unknown
- 2018-09-05 HR HRP20220019TT patent/HRP20220019T1/hr unknown
- 2018-09-05 CN CN201880053052.1A patent/CN111051316B/zh active Active
-
2020
- 2020-02-11 CO CONC2020/0001471A patent/CO2020001471A2/es unknown
- 2020-02-13 CL CL2020000376A patent/CL2020000376A1/es unknown
- 2020-02-14 ZA ZA2020/00970A patent/ZA202000970B/en unknown
- 2020-02-14 PH PH12020500341A patent/PH12020500341A1/en unknown
- 2020-12-11 ZA ZA2020/07737A patent/ZA202007737B/en unknown
-
2022
- 2022-01-10 CY CY20221100025T patent/CY1125355T1/el unknown
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