JP2000262298A - 全血中のグルコース濃度もしくはコレステロール濃度の定量方法 - Google Patents
全血中のグルコース濃度もしくはコレステロール濃度の定量方法Info
- Publication number
- JP2000262298A JP2000262298A JP11068589A JP6858999A JP2000262298A JP 2000262298 A JP2000262298 A JP 2000262298A JP 11068589 A JP11068589 A JP 11068589A JP 6858999 A JP6858999 A JP 6858999A JP 2000262298 A JP2000262298 A JP 2000262298A
- Authority
- JP
- Japan
- Prior art keywords
- concentration
- whole blood
- cholesterol
- glucose
- hematocrit value
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title claims abstract description 136
- 210000004369 blood Anatomy 0.000 title claims abstract description 110
- 239000008280 blood Substances 0.000 title claims abstract description 110
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 107
- 239000008103 glucose Substances 0.000 title claims abstract description 107
- 235000012000 cholesterol Nutrition 0.000 title claims abstract description 67
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 title claims abstract description 17
- 238000005534 hematocrit Methods 0.000 claims abstract description 108
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- SXGZJKUKBWWHRA-UHFFFAOYSA-N 2-(N-morpholiniumyl)ethanesulfonate Chemical compound [O-]S(=O)(=O)CC[NH+]1CCOCC1 SXGZJKUKBWWHRA-UHFFFAOYSA-N 0.000 description 3
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- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
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- FBWNMEQMRUMQSO-UHFFFAOYSA-N tergitol NP-9 Chemical group CCCCCCCCCC1=CC=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)C=C1 FBWNMEQMRUMQSO-UHFFFAOYSA-N 0.000 description 2
- QMBPSOBTBCMICJ-UHFFFAOYSA-N 1,7-dihydronaphthalene Chemical compound C1=CCC2=CCC=CC2=C1 QMBPSOBTBCMICJ-UHFFFAOYSA-N 0.000 description 1
- SVDAGORERCSAIV-UHFFFAOYSA-N 2-(n-ethyl-3-methylanilino)ethanesulfonic acid Chemical compound OS(=O)(=O)CCN(CC)C1=CC=CC(C)=C1 SVDAGORERCSAIV-UHFFFAOYSA-N 0.000 description 1
- WXNZTHHGJRFXKQ-UHFFFAOYSA-N 4-chlorophenol Chemical compound OC1=CC=C(Cl)C=C1 WXNZTHHGJRFXKQ-UHFFFAOYSA-N 0.000 description 1
- SODWJACROGQSMM-UHFFFAOYSA-N 5,6,7,8-tetrahydronaphthalen-1-amine Chemical compound C1CCCC2=C1C=CC=C2N SODWJACROGQSMM-UHFFFAOYSA-N 0.000 description 1
- FWEOQOXTVHGIFQ-UHFFFAOYSA-N 8-anilinonaphthalene-1-sulfonic acid Chemical compound C=12C(S(=O)(=O)O)=CC=CC2=CC=CC=1NC1=CC=CC=C1 FWEOQOXTVHGIFQ-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 229920000936 Agarose Polymers 0.000 description 1
- 240000003291 Armoracia rusticana Species 0.000 description 1
- 235000011330 Armoracia rusticana Nutrition 0.000 description 1
- 240000008564 Boehmeria nivea Species 0.000 description 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
- 241000186146 Brevibacterium Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
- 244000146553 Ceiba pentandra Species 0.000 description 1
- 235000003301 Ceiba pentandra Nutrition 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000223208 Curvularia Species 0.000 description 1
- 239000006173 Good's buffer Substances 0.000 description 1
- 241000219146 Gossypium Species 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 235000004431 Linum usitatissimum Nutrition 0.000 description 1
- 240000006240 Linum usitatissimum Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000012901 Milli-Q water Substances 0.000 description 1
- 241000187654 Nocardia Species 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- 241000228143 Penicillium Species 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
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- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 244000088415 Raphanus sativus Species 0.000 description 1
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 description 1
- 229920000297 Rayon Polymers 0.000 description 1
- IDCBOTIENDVCBQ-UHFFFAOYSA-N TEPP Chemical compound CCOP(=O)(OCC)OP(=O)(OCC)OCC IDCBOTIENDVCBQ-UHFFFAOYSA-N 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 229920002978 Vinylon Polymers 0.000 description 1
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 150000001346 alkyl aryl ethers Chemical class 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
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- 125000004464 hydroxyphenyl group Chemical group 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
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- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- CIPVVROJHKLHJI-UHFFFAOYSA-N n,n-diethyl-3-methylaniline Chemical compound CCN(CC)C1=CC=CC(C)=C1 CIPVVROJHKLHJI-UHFFFAOYSA-N 0.000 description 1
- 150000002790 naphthalenes Chemical class 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
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- 150000002989 phenols Chemical class 0.000 description 1
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- 150000004992 toluidines Chemical class 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11068589A JP2000262298A (ja) | 1999-03-15 | 1999-03-15 | 全血中のグルコース濃度もしくはコレステロール濃度の定量方法 |
| EP00104594A EP1037048A3 (de) | 1999-03-15 | 2000-03-15 | Quantitative Analyse von Glucose oder Cholesterin in Vollblut |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11068589A JP2000262298A (ja) | 1999-03-15 | 1999-03-15 | 全血中のグルコース濃度もしくはコレステロール濃度の定量方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2000262298A true JP2000262298A (ja) | 2000-09-26 |
Family
ID=13378146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11068589A Withdrawn JP2000262298A (ja) | 1999-03-15 | 1999-03-15 | 全血中のグルコース濃度もしくはコレステロール濃度の定量方法 |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP1037048A3 (de) |
| JP (1) | JP2000262298A (de) |
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| JP2003294746A (ja) * | 2002-01-31 | 2003-10-15 | Fuji Photo Film Co Ltd | 生化学解析用ユニットの製造方法 |
| JP2005046145A (ja) * | 2003-07-17 | 2005-02-24 | Ortho Clinical Diagnostics Inc | 高比重リポタンパク質コレステロール定量化のための乾式分析要素 |
| JP2006081492A (ja) * | 2004-09-17 | 2006-03-30 | Chiba Univ | コレステロールの定量方法 |
| WO2007007849A1 (ja) | 2005-07-14 | 2007-01-18 | Matsushita Electric Industrial Co., Ltd. | 分析装置、及び分析方法 |
| WO2009119213A1 (ja) | 2008-03-25 | 2009-10-01 | テルモ株式会社 | ヘマトクリット値または血液成分濃度の測定方法および測定装置 |
| JP2010522336A (ja) * | 2007-03-22 | 2010-07-01 | クオシェント ダイアグノスティックス リミテッド | 全血分析 |
| WO2010140407A1 (ja) * | 2009-06-05 | 2010-12-09 | テルモ株式会社 | 成分測定装置 |
| WO2013147200A1 (ja) * | 2012-03-29 | 2013-10-03 | 積水メディカル株式会社 | ヘマトクリット値の測定方法 |
| JPWO2020183916A1 (de) * | 2019-03-11 | 2020-09-17 |
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| JPS57174099A (en) * | 1981-04-17 | 1982-10-26 | Fuji Photo Film Co Ltd | Color indicator composition for detecting hydrogen peroxide and quantitative analytical film having reagent layer containing the same |
| US4627014A (en) * | 1984-04-09 | 1986-12-02 | Eastman Kodak Company | Method and apparatus for determination of an analyte and method of calibrating such apparatus |
| US4935346A (en) * | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
| DE68927777T2 (de) * | 1988-06-09 | 1997-06-12 | Boehringer Mannheim Corp | Testvorrichtung mit definiertem Volumen |
| US5126275A (en) * | 1990-09-19 | 1992-06-30 | Miles Inc. | Analytical method using tetrazolium salt indicators having a reflectance plateau |
| DE69227545T2 (de) * | 1991-07-12 | 1999-04-29 | Robinson, Mark R., Albuquerque, N.Mex. | Oximeter zur zuverlässigen klinischen Bestimmung der Blutsauerstoffsättigung in einem Fötus |
-
1999
- 1999-03-15 JP JP11068589A patent/JP2000262298A/ja not_active Withdrawn
-
2000
- 2000-03-15 EP EP00104594A patent/EP1037048A3/de not_active Withdrawn
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| JP2005046145A (ja) * | 2003-07-17 | 2005-02-24 | Ortho Clinical Diagnostics Inc | 高比重リポタンパク質コレステロール定量化のための乾式分析要素 |
| JP2006081492A (ja) * | 2004-09-17 | 2006-03-30 | Chiba Univ | コレステロールの定量方法 |
| WO2007007849A1 (ja) | 2005-07-14 | 2007-01-18 | Matsushita Electric Industrial Co., Ltd. | 分析装置、及び分析方法 |
| JP2010522336A (ja) * | 2007-03-22 | 2010-07-01 | クオシェント ダイアグノスティックス リミテッド | 全血分析 |
| JP2009236487A (ja) * | 2008-03-25 | 2009-10-15 | Terumo Corp | ヘマトクリット値または血液成分濃度の測定方法および測定装置 |
| WO2009119213A1 (ja) | 2008-03-25 | 2009-10-01 | テルモ株式会社 | ヘマトクリット値または血液成分濃度の測定方法および測定装置 |
| WO2010140407A1 (ja) * | 2009-06-05 | 2010-12-09 | テルモ株式会社 | 成分測定装置 |
| JP2010281751A (ja) * | 2009-06-05 | 2010-12-16 | Terumo Corp | 成分測定装置 |
| WO2013147200A1 (ja) * | 2012-03-29 | 2013-10-03 | 積水メディカル株式会社 | ヘマトクリット値の測定方法 |
| JPWO2013147200A1 (ja) * | 2012-03-29 | 2015-12-14 | 積水メディカル株式会社 | ヘマトクリット値の測定方法 |
| JPWO2020183916A1 (de) * | 2019-03-11 | 2020-09-17 | ||
| WO2020183916A1 (ja) * | 2019-03-11 | 2020-09-17 | テルモ株式会社 | 血糖値算出プログラム、血糖値算出方法及び血糖値測定装置 |
| JP7372310B2 (ja) | 2019-03-11 | 2023-10-31 | テルモ株式会社 | 血糖値算出プログラム、血糖値算出方法及び血糖値測定装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1037048A2 (de) | 2000-09-20 |
| EP1037048A3 (de) | 2000-12-20 |
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