JP2000502055A5 - - Google Patents

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Publication number
JP2000502055A5
JP2000502055A5 JP1997520123A JP52012397A JP2000502055A5 JP 2000502055 A5 JP2000502055 A5 JP 2000502055A5 JP 1997520123 A JP1997520123 A JP 1997520123A JP 52012397 A JP52012397 A JP 52012397A JP 2000502055 A5 JP2000502055 A5 JP 2000502055A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997520123A
Other languages
English (en)
Japanese (ja)
Other versions
JP3987575B2 (ja
JP2000502055A (ja
Filing date
Publication date
Priority claimed from US08/562,652 external-priority patent/US5843903A/en
Application filed filed Critical
Publication of JP2000502055A publication Critical patent/JP2000502055A/ja
Publication of JP2000502055A5 publication Critical patent/JP2000502055A5/ja
Application granted granted Critical
Publication of JP3987575B2 publication Critical patent/JP3987575B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP52012397A 1995-11-27 1996-11-14 標的細胞毒性アントラサイクリン類似体 Expired - Lifetime JP3987575B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/562,652 1995-11-27
US08/562,652 US5843903A (en) 1995-11-27 1995-11-27 Targeted cytotoxic anthracycline analogs
PCT/EP1996/005029 WO1997019954A1 (en) 1995-11-27 1996-11-14 Targeted cytotoxic anthracycline analogs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006309698A Division JP4778405B2 (ja) 1995-11-27 2006-11-15 標的細胞毒性アントラサイクリン類似体の合成方法

Publications (3)

Publication Number Publication Date
JP2000502055A JP2000502055A (ja) 2000-02-22
JP2000502055A5 true JP2000502055A5 (2) 2004-09-16
JP3987575B2 JP3987575B2 (ja) 2007-10-10

Family

ID=24247176

Family Applications (2)

Application Number Title Priority Date Filing Date
JP52012397A Expired - Lifetime JP3987575B2 (ja) 1995-11-27 1996-11-14 標的細胞毒性アントラサイクリン類似体
JP2006309698A Expired - Lifetime JP4778405B2 (ja) 1995-11-27 2006-11-15 標的細胞毒性アントラサイクリン類似体の合成方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006309698A Expired - Lifetime JP4778405B2 (ja) 1995-11-27 2006-11-15 標的細胞毒性アントラサイクリン類似体の合成方法

Country Status (27)

Country Link
US (2) US5843903A (2)
EP (2) EP1384710B1 (2)
JP (2) JP3987575B2 (2)
KR (2) KR100445754B1 (2)
CN (2) CN1137136C (2)
AT (2) ATE251179T1 (2)
AU (1) AU709539B2 (2)
BR (1) BR9611647B1 (2)
CA (2) CA2238574C (2)
CZ (1) CZ297297B6 (2)
DE (2) DE69637604D1 (2)
DK (2) DK0863917T3 (2)
EA (1) EA001372B1 (2)
ES (2) ES2310222T3 (2)
HK (1) HK1052920B (2)
HU (1) HU229870B1 (2)
IL (3) IL119691A (2)
IS (2) IS2178B (2)
MX (1) MX9804119A (2)
NO (2) NO324035B1 (2)
NZ (1) NZ322054A (2)
PL (3) PL188786B1 (2)
PT (2) PT1384710E (2)
SK (2) SK284672B6 (2)
UA (1) UA67722C2 (2)
WO (1) WO1997019954A1 (2)
ZA (1) ZA969709B (2)

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US6528481B1 (en) 1999-02-16 2003-03-04 The Burnam Institute NG2/HM proteoglycan-binding peptides that home to angiogenic vasculature and related methods
US6380161B1 (en) 1999-06-21 2002-04-30 Inkine Pharmaceutical Company, Inc. Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions
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US20040170955A1 (en) 2000-09-08 2004-09-02 Wadih Arap Human and mouse targeting peptides identified by phage display
US7420030B2 (en) 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
US7452964B2 (en) 2001-09-07 2008-11-18 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides against placenta and adipose tissues
KR100420007B1 (ko) * 2001-04-25 2004-03-02 노영쇠 안트라사이클린 유도체 및 이를 포함하는 항암제
BR0212897A (pt) 2001-09-21 2004-08-24 Univ Tulane Conjugados de análogos de somatostatina ou bombesina diagnóstica ou terapêutica e usos dos mesmos
EP1531846A4 (en) * 2002-02-27 2006-04-19 Us Gov Health & Human Serv Conjugates of ligand, linker and cytotoxic agent and related compositions and methods of use
EP1487493B1 (en) 2002-03-01 2010-01-20 The Administrators of The Tulane Educational Fund Conjugates of cytotoxic agents and biologically active peptides
US7544767B2 (en) 2002-04-05 2009-06-09 Burnham Institute For Medical Research HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells
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US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
EP2075014B9 (en) 2002-05-24 2012-02-01 Angiotech International Ag Compositions and methods for coating medical implants
KR20050084599A (ko) 2002-09-26 2005-08-26 안지오테크 인터내셔날 아게 혈관주위 랩
EP2181704B1 (en) 2002-12-30 2015-05-06 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US20040202666A1 (en) * 2003-01-24 2004-10-14 Immunomedics, Inc. Anti-cancer anthracycline drug-antibody conjugates
US20050043215A1 (en) 2003-02-19 2005-02-24 Tamara Minko Complex drug delivery composition and method for treating cancer
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US7097993B2 (en) 2003-06-25 2006-08-29 Wisconsin Alumni Research Foundation Method for identifying an agent that modulates type 1 phosphatidylinositol phosphate kinase isoform β661 activity
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US20070060534A1 (en) * 2005-06-30 2007-03-15 Threshold Pharmaceuticals, Inc. Anthracycline analogs
JP5340155B2 (ja) * 2006-09-06 2013-11-13 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 細胞結合分子を有するジソラゾールのコンジュゲート及びそれらの誘導体、新規ジソラゾール誘導体、それらの製法ならびに使用
EP1900742A1 (en) 2006-09-07 2008-03-19 AEterna Zentaris GmbH Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof
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CN102159248B (zh) * 2008-07-15 2013-09-11 健泰科生物技术公司 蒽环类衍生物缀合物、它们的制备方法以及它们作为抗肿瘤化合物的用途
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CN102050856B (zh) * 2009-11-03 2014-04-30 天津和美生物技术有限公司 具有高活性的表阿霉素的衍生物及其制备和应用
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CN105198966B (zh) * 2014-06-26 2019-06-21 中国人民解放军军事医学科学院毒物药物研究所 GnRH类似物-细胞毒分子缀合物、其制备方法及用途
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JP7057278B2 (ja) 2015-10-28 2022-04-19 ターベダ セラピューティクス インコーポレイテッド Sstr標的化コンジュゲート及び粒子並びにその製剤
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WO2021068051A1 (en) * 2018-11-13 2021-04-15 Provincial Health Services Authority Radiolabeled bombesin-derived compounds for in vivo imaging of gastrin-releasing peptide receptor (grpr) and treatment of grpr-related disorders
CA3246188A1 (en) 2022-03-25 2023-09-28 The University Of British Columbia Radiolabeled compounds for in vivo imaging of the gastrin-releasing peptide (GRPR) receptor and treatment of GRPR-related disorders

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