JP2008536986A - 共有結合グラフトを介した生物活性分子を含む高度に多孔質のポリマー材料 - Google Patents

共有結合グラフトを介した生物活性分子を含む高度に多孔質のポリマー材料 Download PDF

Info

Publication number
JP2008536986A
JP2008536986A JP2008507009A JP2008507009A JP2008536986A JP 2008536986 A JP2008536986 A JP 2008536986A JP 2008507009 A JP2008507009 A JP 2008507009A JP 2008507009 A JP2008507009 A JP 2008507009A JP 2008536986 A JP2008536986 A JP 2008536986A
Authority
JP
Japan
Prior art keywords
highly porous
species
monomer
bioactive species
bioactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008507009A
Other languages
English (en)
Japanese (ja)
Inventor
ジェンス クリストフ シース，
セバスティエン ピエレ，
ニール ロナルド キャメロン，
ヘスト， ジャン コーネリス マリア ヴァン
ポール ワイマン，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of JP2008536986A publication Critical patent/JP2008536986A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/32—Polymerisation in water-in-oil emulsions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Graft Or Block Polymers (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
JP2008507009A 2005-04-22 2006-04-21 共有結合グラフトを介した生物活性分子を含む高度に多孔質のポリマー材料 Pending JP2008536986A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05075957 2005-04-22
PCT/EP2006/003677 WO2006111399A2 (en) 2005-04-22 2006-04-21 Highly porous polymeric materials comprising biologically active molecules via covalent grafting

Publications (1)

Publication Number Publication Date
JP2008536986A true JP2008536986A (ja) 2008-09-11

Family

ID=36974715

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008507009A Pending JP2008536986A (ja) 2005-04-22 2006-04-21 共有結合グラフトを介した生物活性分子を含む高度に多孔質のポリマー材料

Country Status (7)

Country Link
US (1) US20090215913A1 (pt)
EP (1) EP1871878A2 (pt)
JP (1) JP2008536986A (pt)
KR (1) KR20080010402A (pt)
CN (1) CN101163789A (pt)
BR (1) BRPI0608100A2 (pt)
WO (1) WO2006111399A2 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019022885A (ja) * 2010-03-30 2019-02-14 サーモディクス，インコーポレイテッド 分解性光架橋剤

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2323778A1 (fr) * 2008-08-13 2011-05-25 Long Lasting Innovation - L2i (Société À Responsabilité Limitée) Procede pour la fixation de molecules actives sur un support, element actif obtenu par ce procede et composition chimique pour la mise en uvre de ce procede
WO2011110662A1 (en) 2010-03-11 2011-09-15 Danmarks Tekniske Universitet Supported biologically active compounds
US9062245B2 (en) 2011-02-09 2015-06-23 Technion Research & Development Foundation Limited Liquid-retaining elastomeric compositions
US9180094B2 (en) 2011-10-12 2015-11-10 The Texas A&M University System High porosity materials, scaffolds, and method of making
US20160243277A1 (en) * 2013-09-23 2016-08-25 The Texas A & M University System Fast curing porous materials and control thereof
US10363215B2 (en) 2013-11-08 2019-07-30 The Texas A&M University System Porous microparticles with high loading efficiencies
IL245656B (en) 2016-05-16 2018-02-28 Technion Res & Dev Foundation Polymer structures with high absorption capacity
WO2018002916A1 (en) 2016-06-26 2018-01-04 Technion Research & Development Foundation Limited Hhh
IL247302B (en) 2016-08-16 2019-03-31 Technion Res & Dev Foundation Systems for releasing materials based on polymer emulsions
CN107164359B (zh) * 2017-06-30 2020-03-17 鲁东大学 一种具有良好热稳定性的葡萄糖氧化酶纳米凝胶的制备方法
IL253431A0 (en) 2017-07-11 2017-09-28 Technion Res & Dev Foundation Flexible compounds store liquids, their preparation processes and their uses
WO2019016816A1 (en) 2017-07-19 2019-01-24 Technion Research & Development Foundation Limited HYDROGELS WITH EMULSION MATRIX DOUBLELY RETICULATED BY REVERSIBLE METAL COORDINATION
IL255404B (en) 2017-11-02 2018-10-31 Technion Res & Dev Foundation A zwitterionic hydrogel in the configuration of an internal multiphase emulsion

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5836388A (ja) * 1981-08-05 1983-03-03 レ−ム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 求核性基を含有する基質を結合するための反応性単位を有する表面積の大きい系、固定方法および触媒系、ならびに指示薬または吸収体
JPS6368618A (ja) * 1986-08-28 1988-03-28 ヘキスト・アクチエンゲゼルシヤフト 生物学的に活性な物質の固定化用担体
JPH022347A (ja) * 1987-12-22 1990-01-08 Unilever Nv 生物学的に活性なシステム
JPH08322915A (ja) * 1995-05-29 1996-12-10 Synbolon Corp 病原体の失活方法
JPH11322997A (ja) * 1998-05-14 1999-11-26 Dainippon Ink & Chem Inc 多孔質ビーズの製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101113201B1 (ko) * 2003-02-19 2012-04-12 나트릭스 세퍼레이션즈, 인코포레이티드 지지된 다공성 젤을 함유하는 복합재

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5836388A (ja) * 1981-08-05 1983-03-03 レ−ム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 求核性基を含有する基質を結合するための反応性単位を有する表面積の大きい系、固定方法および触媒系、ならびに指示薬または吸収体
JPS6368618A (ja) * 1986-08-28 1988-03-28 ヘキスト・アクチエンゲゼルシヤフト 生物学的に活性な物質の固定化用担体
JPH022347A (ja) * 1987-12-22 1990-01-08 Unilever Nv 生物学的に活性なシステム
JPH08322915A (ja) * 1995-05-29 1996-12-10 Synbolon Corp 病原体の失活方法
JPH11322997A (ja) * 1998-05-14 1999-11-26 Dainippon Ink & Chem Inc 多孔質ビーズの製造方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019022885A (ja) * 2010-03-30 2019-02-14 サーモディクス，インコーポレイテッド 分解性光架橋剤

Also Published As

Publication number Publication date
BRPI0608100A2 (pt) 2009-11-03
WO2006111399A8 (en) 2006-12-28
KR20080010402A (ko) 2008-01-30
WO2006111399A3 (en) 2007-02-08
WO2006111399A2 (en) 2006-10-26
US20090215913A1 (en) 2009-08-27
EP1871878A2 (en) 2008-01-02
CN101163789A (zh) 2008-04-16

Similar Documents

Publication Publication Date Title
Pierre et al. Covalent enzyme immobilization onto photopolymerized highly porous monoliths
Kazybayeva et al. Thiol-ene “click reactions” as a promising approach to polymer materials
Ito et al. An insulin-releasing system that is responsive to glucose
Vitola et al. PVDF membrane biofunctionalization by chemical grafting
Audouin et al. Protein immobilization onto poly (acrylic acid) functional macroporous polyHIPE obtained by surface-initiated ARGET ATRP
US8703058B1 (en) Microfluidic devices and methods including porous polymer monoliths
EP1996633B1 (fr) Empreintes moleculaires pour une reconnaissance en milieux aqueux, leurs procedes de preparation et leurs utilisations
US20090215913A1 (en) Highly porous polymeric materials comprising biologically active molecules via covalent grafting
EP0106769B1 (fr) Support particulaire greffé en surface, son procédé de préparation et adsorbants pour chromatographie d'affinité incorporant ce support, ainsi que leur utilisation, notamment en biologie
EP3510041B1 (en) Processes for separating aggregated proteins from monomeric proteins in a biological solution
EP2500088A2 (en) Molecular recognition material and production method thereof
CA2443562A1 (en) High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon
CN1653189A (zh) 制备聚合物涂层的方法
CN109689189B (zh) 官能化共聚物及其使用
Nakamae et al. Lysozyme loading and release from hydrogels carrying pendant phosphate groups
KR20050121251A (ko) 고분자전해질을 함유하는 고내부상 에멀젼 폼
JPH05279411A (ja) 担体に結合された生物学的に活性な物質
Kumar et al. Green synthesis of polymer materials via enzyme-initiated RAFT polymerization
JP3979612B2 (ja) センサー及びその製造方法
JPS6368618A (ja) 生物学的に活性な物質の固定化用担体
CN115364824A (zh) 一种四溴双酚a分子印迹膜及其制备方法和应用
JP3398985B2 (ja) センサーの製造方法
EP0029411B1 (fr) Composition adhésive pour le dépôt d'un revêtement adhésif fixateur de molécules biofonctionnelles, revêtement obtenu et procédé pour sa préparation, substrat recouvert du revêtement et son utilisation comme biocatalyseur
Peppas et al. New biomaterials for intelligent biosensing, recognitive drug delivery and therapeutics
Kalim et al. Catalysis of a β-elimination applying membranes with incorporated molecularly imprinted polymer particles

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090420

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120207

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20120208

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120710