JP2014503528A - カゼインキナーゼ１δ（ＣＫ１δ）阻害剤及びタウオパチーなどの神経変性疾患の治療におけるその使用 - Google Patents

カゼインキナーゼ１δ（ＣＫ１δ）阻害剤及びタウオパチーなどの神経変性疾患の治療におけるその使用 Download PDF

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JP2014503528A
JP2014503528A JP2013543881A JP2013543881A JP2014503528A JP 2014503528 A JP2014503528 A JP 2014503528A JP 2013543881 A JP2013543881 A JP 2013543881A JP 2013543881 A JP2013543881 A JP 2013543881A JP 2014503528 A JP2014503528 A JP 2014503528A
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alkyl
aryl
conh
heteroaryl
compound
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JP2014503528A5 (2
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エム．シェリダン ジョセプフ
アール．ヘアル ジョナトハン
ディー．オー．ハミルトン ウイルリアム
ピケ イアン
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エレクトロプホレトイクス リミテッド
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Priority claimed from GBGB1109162.6A external-priority patent/GB201109162D0/en
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Publication of JP2014503528A publication Critical patent/JP2014503528A/ja
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JP2013543881A 2010-12-14 2011-12-14 カゼインキナーゼ１δ（ＣＫ１δ）阻害剤及びタウオパチーなどの神経変性疾患の治療におけるその使用 Pending JP2014503528A (ja)

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JP2018521119A (ja) * 2015-06-01 2018-08-02 バンタム、ファーマシューティカル、リミテッド、ライアビリティー、カンパニーＢａｎｔａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌ， Ｌｌｃ 置換ピラゾールおよびピロール化合物、および翻訳開始の阻害およびこれらに関連する疾患および障害の治療のためにこれらを用いる方法
JP2018525345A (ja) * 2015-07-01 2018-09-06 ノースウェスタン ユニバーシティ 置換キナゾリン化合物及びグルコセレブロシダーゼ活性の調節のためのその使用
JP2018535968A (ja) * 2015-11-02 2018-12-06 ヤンセン ファーマシューティカ エヌ．ベー． ［１，２，４］トリアゾロ［１，５−ａ］ピリミジン−７−イル化合物
JP2019502673A (ja) * 2015-12-07 2019-01-31 ヒノバ ファーマシューティカルズ インコーポレイテッド キノリン系化合物とその調製方法および尿酸トランスポータ阻害剤類薬物としての使用
JP2019529514A (ja) * 2015-10-05 2019-10-17 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク オートファジーフラックス及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法
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JP2020519644A (ja) * 2017-05-12 2020-07-02 ボード オブ トラスティーズ オブ ザ サザン イリノイ ユニバーシティ オン ビハーフ オブ サザン イリノイ ユニバーシティ エドワーズビル ３，４，５−三置換−１，２，４−トリアゾールおよび３，４，５−三置換−３−チオ−１，２，４−トリアゾール、ならびにそれらの使用
JP2021507944A (ja) * 2017-12-21 2021-02-25 グリアファーム エスエー 運動ニューロン疾患を含む神経障害のための組成物および治療方法
JP2021507945A (ja) * 2017-12-21 2021-02-25 グリアファーム エスエー 認知症を含む神経障害のための組成物および治療方法
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KR20230146639A (ko) * 2021-04-21 2023-10-19 장춘 진사이언스 파마슈티컬 씨오., 엘티디. 이미다졸 함유 축합고리계 유도체, 이의 제조방법 및 이의 의약적 용도
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JP2022529541A (ja) * 2019-04-26 2022-06-22 セルジーン コーポレーション ヘテロ環式化合物ならびに蠕虫感染および疾患におけるその使用
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JP2024505708A (ja) * 2021-02-08 2024-02-07 セレヴァンス，インコーポレイテッド 新規化合物
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KR20230146639A (ko) * 2021-04-21 2023-10-19 장춘 진사이언스 파마슈티컬 씨오., 엘티디. 이미다졸 함유 축합고리계 유도체, 이의 제조방법 및 이의 의약적 용도
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JP2025528595A (ja) * 2022-10-19 2025-08-28 長春金賽薬業有限責任公司 Ｎｋ３ｒアンタゴニストの結晶形及びその調製方法と用途
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