JP3433295B2 - キシリトールの製造のための組換え方法および宿主 - Google Patents

キシリトールの製造のための組換え方法および宿主

Info

Publication number
JP3433295B2
JP3433295B2 JP51074894A JP51074894A JP3433295B2 JP 3433295 B2 JP3433295 B2 JP 3433295B2 JP 51074894 A JP51074894 A JP 51074894A JP 51074894 A JP51074894 A JP 51074894A JP 3433295 B2 JP3433295 B2 JP 3433295B2
Authority
JP
Japan
Prior art keywords
host
dehydrogenase
gene
phosphate
xylitol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP51074894A
Other languages
English (en)
Japanese (ja)
Other versions
JPH08505522A (ja
Inventor
アヌ マリュッカ ハルッキ
アンドレイ ノボミロビッチ ミアスニコフ
ユーハ ヘイッキ アンテロ アパヤラハティ
オッシ アンテロ パスチネン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
XYROFIN OSAK YHTIO
Original Assignee
XYROFIN OSAK YHTIO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by XYROFIN OSAK YHTIO filed Critical XYROFIN OSAK YHTIO
Publication of JPH08505522A publication Critical patent/JPH08505522A/ja
Application granted granted Critical
Publication of JP3433295B2 publication Critical patent/JP3433295B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP51074894A 1992-11-05 1993-11-05 キシリトールの製造のための組換え方法および宿主 Expired - Fee Related JP3433295B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97332592A 1992-11-05 1992-11-05
US07/973,325 1992-11-05
PCT/FI1993/000450 WO1994010325A1 (en) 1992-11-05 1993-11-05 Recombinant method and host for manufacture of xylitol

Publications (2)

Publication Number Publication Date
JPH08505522A JPH08505522A (ja) 1996-06-18
JP3433295B2 true JP3433295B2 (ja) 2003-08-04

Family

ID=25520759

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51074894A Expired - Fee Related JP3433295B2 (ja) 1992-11-05 1993-11-05 キシリトールの製造のための組換え方法および宿主

Country Status (15)

Country Link
JP (1) JP3433295B2 (de)
KR (1) KR950704503A (de)
AT (1) ATE184917T1 (de)
AU (1) AU5421594A (de)
BR (1) BR9307391A (de)
CA (1) CA2148622A1 (de)
DE (1) DE69326559T2 (de)
ES (1) ES2139024T3 (de)
FI (1) FI108300B (de)
HU (1) HU219016B (de)
NO (1) NO951747L (de)
NZ (1) NZ257561A (de)
PL (1) PL178040B1 (de)
RU (1) RU2142999C1 (de)
WO (1) WO1994010325A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6723540B1 (en) 1992-11-05 2004-04-20 Xyrofin Oy Manufacture of xylitol using recombinant microbial hosts
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
GB9514538D0 (en) 1995-07-15 1995-09-13 Cerestar Holding Bv Process for the production of xylitol
FR2762011B1 (fr) * 1997-04-11 1999-06-25 Roquette Freres Procede de preparation de ribitol par voie fermentaire et souche de microorganismes mise en oeuvre dans ce procede
FR2765589B1 (fr) * 1997-07-03 1999-09-17 Roquette Freres Fragment d'adn comprenant le promoteur de la ribulose reductase nadph specifique de yamadazyma ohmeri, vecteur le contenant et procede de preparation de proteines utilisant ce vecteur
JPH11266888A (ja) 1997-10-17 1999-10-05 Ajinomoto Co Inc キシリトールの製造法
JP3855486B2 (ja) * 1997-10-17 2006-12-13 味の素株式会社 キシリトールの製造法
US6335177B1 (en) 1998-07-08 2002-01-01 Ajinomoto Co., Inc. Microorganisms and method for producing xylitol or d-xylulose
PE20001023A1 (es) * 1998-07-30 2000-10-10 Ajinomoto Kk Deshidrogenasa de xilitol de bacterias de acido acetico y su gen
EP1147196A4 (de) 1998-12-08 2002-10-16 Childrens Hosp Medical Center Polymorphe loci die escherichia coli 0157:h7 von anderen stämmen unterscheiden
JP2000210095A (ja) 1999-01-20 2000-08-02 Ajinomoto Co Inc キシリト―ル又はｄ―キシルロ―スの製造法
JP2000295994A (ja) * 1999-02-09 2000-10-24 Ajinomoto Co Inc キシリトールの製造法
US6830903B1 (en) 1999-07-23 2004-12-14 Archer-Daniels-Midland Company Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene
WO2001007626A2 (en) 1999-07-23 2001-02-01 Archer-Daniels-Midland Company Methods for producing l-amino acids by increasing cellular nadph
CN1221664C (zh) * 2000-01-21 2005-10-05 达尼斯科甜味剂股份有限公司 五碳糖和糖醇的生产
US6894199B2 (en) 2001-04-27 2005-05-17 Danisco Sweeteners Oy Process for the production of xylitol
GB2406855A (en) * 2003-02-07 2005-04-13 Danisco Sweeteners Oy Production of xylitol from a carbon source other than xylose and xylulose
WO2005113759A2 (en) * 2004-05-19 2005-12-01 Biotechnology Research And Development Corporation Microbial production of xylitol via a hexose phosphate and a pentose phosphate intermediate
EP1766021B1 (de) * 2004-05-20 2012-05-09 AES Chemunex S.A. Polynukleotide zum nachweis von escherichia coli o157:h7- und escherichia coli o157:nm-verotoxinproduzenten
KR101246780B1 (ko) * 2010-10-06 2013-03-26 한국과학기술원 아라비노스 대사경로가 도입된 자일리톨 생산균주 및 이를 이용한 자일리톨 생산방법
DK2957640T3 (en) 2014-06-18 2018-06-25 Roquette Freres Preparation of xylitol from glucose by a recombinant strain
JP2025516502A (ja) * 2022-05-09 2025-05-30 カーギル インコーポレイテッド ポリオールの生成のための遺伝的に改変された酵母及び発酵方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS514279B1 (de) * 1970-05-26 1976-02-10
US4075406A (en) * 1974-04-22 1978-02-21 Suomen Sokeri Osakeyhtio Process for making xylose
US4008285A (en) * 1974-04-22 1977-02-15 Melaja Asko J Process for making xylitol
US4066711A (en) * 1976-03-15 1978-01-03 Suomen Sokeri Osakeyhtio (Finnish Sugar Company) Method for recovering xylitol
DE4009676A1 (de) * 1990-03-26 1991-10-02 Rhein Biotech Proz & Prod Gmbh Dna-sequenz, umfassend ein fuer xylosereduktase und/oder xylitoldehydrogenase codierendes strukturgen
FI901771A7 (fi) * 1990-04-06 1991-10-07 Valtion Teknillinen Anvaendning av xylos hos hybridjaest.

Also Published As

Publication number Publication date
RU95113172A (ru) 1997-03-27
HU219016B (hu) 2001-01-29
RU2142999C1 (ru) 1999-12-20
ES2139024T3 (es) 2000-02-01
JPH08505522A (ja) 1996-06-18
CA2148622A1 (en) 1994-05-11
PL308742A1 (en) 1995-08-21
NO951747L (no) 1995-07-05
DE69326559D1 (de) 1999-10-28
NO951747D0 (no) 1995-05-04
PL178040B1 (pl) 2000-02-29
ATE184917T1 (de) 1999-10-15
KR950704503A (ko) 1995-11-20
FI952148L (fi) 1995-07-04
FI952148A0 (fi) 1995-05-04
AU5421594A (en) 1994-05-24
HUT72187A (en) 1996-03-28
FI108300B (fi) 2001-12-31
NZ257561A (en) 1996-09-25
HU9501288D0 (en) 1995-06-28
DE69326559T2 (de) 2000-02-10
BR9307391A (pt) 1999-08-31
WO1994010325A1 (en) 1994-05-11

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