PL178040B1 - Sposób wytwarzania ksylitolu i zrekombinowany gospodarz drobnoustrojowy - Google Patents

Sposób wytwarzania ksylitolu i zrekombinowany gospodarz drobnoustrojowy

Info

Publication number: PL178040B1
Authority: PL; Poland
Prior art keywords: xylitol; arabitol; dehydrogenase; host; glucose
Prior art date: 1992-11-05

Application number

PL93308742A

Other languages

English (en)

Polish (pl)

Other versions

PL308742A1 (en

Inventor

Anu M. Harkki

Andrey N. Myasnikov

Juha H. A. Apajalahti

Ossi A. Pastinen

Original Assignee

Xyrofin Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-05

Filing date

1993-11-05

Publication date

2000-02-29

1993-11-05 Application filed by Xyrofin Oy filed Critical Xyrofin Oy

1995-08-21 Publication of PL308742A1 publication Critical patent/PL308742A1/xx

2000-02-29 Publication of PL178040B1 publication Critical patent/PL178040B1/pl

Links

238000000034 method Methods 0.000 title claims abstract description 113
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235000010447 xylitol Nutrition 0.000 claims abstract description 120
HEBKCHPVOIAQTA-QWWZWVQMSA-N D-arabinitol Chemical compound OC[C@@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-QWWZWVQMSA-N 0.000 claims abstract description 90
HEBKCHPVOIAQTA-NGQZWQHPSA-N D-Arabitol Natural products OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 claims abstract description 61
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210000001236 prokaryotic cell Anatomy 0.000 description 1
210000001938 protoplast Anatomy 0.000 description 1
230000008707 rearrangement Effects 0.000 description 1
230000003362 replicative effect Effects 0.000 description 1
230000000241 respiratory effect Effects 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
230000001177 retroviral effect Effects 0.000 description 1
238000010839 reverse transcription Methods 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
108020005610 ribose 5-phosphate isomerase Proteins 0.000 description 1
108020004418 ribosomal RNA Proteins 0.000 description 1
238000000926 separation method Methods 0.000 description 1
238000002741 site-directed mutagenesis Methods 0.000 description 1
238000011172 small scale experimental method Methods 0.000 description 1
239000001632 sodium acetate Substances 0.000 description 1
235000017281 sodium acetate Nutrition 0.000 description 1
239000001488 sodium phosphate Substances 0.000 description 1
229910000162 sodium phosphate Inorganic materials 0.000 description 1
239000012064 sodium phosphate buffer Substances 0.000 description 1
AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
235000019345 sodium thiosulphate Nutrition 0.000 description 1
244000000000 soil microbiome Species 0.000 description 1
235000013555 soy sauce Nutrition 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
239000008223 sterile water Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
238000000856 sucrose gradient centrifugation Methods 0.000 description 1
230000001629 suppression Effects 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
230000008685 targeting Effects 0.000 description 1
238000012360 testing method Methods 0.000 description 1
229960002180 tetracycline Drugs 0.000 description 1
229930101283 tetracycline Natural products 0.000 description 1
235000019364 tetracycline Nutrition 0.000 description 1
150000003522 tetracyclines Chemical class 0.000 description 1
229960002363 thiamine pyrophosphate Drugs 0.000 description 1
235000008170 thiamine pyrophosphate Nutrition 0.000 description 1
239000011678 thiamine pyrophosphate Substances 0.000 description 1
YXVCLPJQTZXJLH-UHFFFAOYSA-N thiamine(1+) diphosphate chloride Chemical compound [Cl-].CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N YXVCLPJQTZXJLH-UHFFFAOYSA-N 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
230000005030 transcription termination Effects 0.000 description 1
238000012546 transfer Methods 0.000 description 1
238000011426 transformation method Methods 0.000 description 1
230000014621 translational initiation Effects 0.000 description 1
239000001226 triphosphate Substances 0.000 description 1
235000011178 triphosphate Nutrition 0.000 description 1
125000002264 triphosphate group Chemical class [H]OP(=O)(O[H])OP(=O)(O[H])OP(=O)(O[H])O* 0.000 description 1
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
239000012137 tryptone Substances 0.000 description 1
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
239000013603 viral vector Substances 0.000 description 1
239000002023 wood Substances 0.000 description 1
229920001221 xylan Polymers 0.000 description 1
150000004823 xylans Chemical class 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL93308742A 1992-11-05 1993-11-05 Sposób wytwarzania ksylitolu i zrekombinowany gospodarz drobnoustrojowy PL178040B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US97332592A	1992-11-05	1992-11-05
PCT/FI1993/000450 WO1994010325A1 (en)	1992-11-05	1993-11-05	Recombinant method and host for manufacture of xylitol

Publications (2)

Publication Number	Publication Date
PL308742A1 PL308742A1 (en)	1995-08-21
PL178040B1 true PL178040B1 (pl)	2000-02-29

Family

ID=25520759

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL93308742A PL178040B1 (pl)	1992-11-05	1993-11-05	Sposób wytwarzania ksylitolu i zrekombinowany gospodarz drobnoustrojowy

Country Status (15)

Country	Link
JP (1)	JP3433295B2 (de)
KR (1)	KR950704503A (de)
AT (1)	ATE184917T1 (de)
AU (1)	AU5421594A (de)
BR (1)	BR9307391A (de)
CA (1)	CA2148622A1 (de)
DE (1)	DE69326559T2 (de)
ES (1)	ES2139024T3 (de)
FI (1)	FI108300B (de)
HU (1)	HU219016B (de)
NO (1)	NO951747L (de)
NZ (1)	NZ257561A (de)
PL (1)	PL178040B1 (de)
RU (1)	RU2142999C1 (de)
WO (1)	WO1994010325A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7226761B2 (en)	1992-11-05	2007-06-05	Danisco Sweeteners Oy	Manufacture of five-carbon sugars and sugar alcohols
US6723540B1 (en)	1992-11-05	2004-04-20	Xyrofin Oy	Manufacture of xylitol using recombinant microbial hosts
GB9514538D0 (en) *	1995-07-15	1995-09-13	Cerestar Holding Bv	Process for the production of xylitol
FR2762011B1 (fr) *	1997-04-11	1999-06-25	Roquette Freres	Procede de preparation de ribitol par voie fermentaire et souche de microorganismes mise en oeuvre dans ce procede
FR2765589B1 (fr) *	1997-07-03	1999-09-17	Roquette Freres	Fragment d'adn comprenant le promoteur de la ribulose reductase nadph specifique de yamadazyma ohmeri, vecteur le contenant et procede de preparation de proteines utilisant ce vecteur
JP3855486B2 (ja) *	1997-10-17	2006-12-13	味の素株式会社	キシリトールの製造法
JPH11266888A (ja) *	1997-10-17	1999-10-05	Ajinomoto Co Inc	キシリトールの製造法
US6335177B1 (en)	1998-07-08	2002-01-01	Ajinomoto Co., Inc.	Microorganisms and method for producing xylitol or d-xylulose
PE20001023A1 (es)	1998-07-30	2000-10-10	Ajinomoto Kk	Deshidrogenasa de xilitol de bacterias de acido acetico y su gen
CN1333831A (zh)	1998-12-08	2002-01-30	儿童医院及地区医疗中心	区分大肠杆菌0157∶h7和其它菌株的多态性位点
JP2000210095A (ja) *	1999-01-20	2000-08-02	Ajinomoto Co Inc	キシリト―ル又はｄ―キシルロ―スの製造法
JP2000295994A (ja) *	1999-02-09	2000-10-24	Ajinomoto Co Inc	キシリトールの製造法
CA2377693C (en)	1999-07-23	2016-11-08	Archer-Daniels-Midland Company	Methods for producing l-amino acids
US6830903B1 (en)	1999-07-23	2004-12-14	Archer-Daniels-Midland Company	Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene
EP1254244B1 (de) *	2000-01-21	2010-04-14	Danisco A/S	Herstellung von durch 5 kohlenstoffatome charakterisierte zucker und zuckeralkohole
US6894199B2 (en)	2001-04-27	2005-05-17	Danisco Sweeteners Oy	Process for the production of xylitol
GB2406855A (en) *	2003-02-07	2005-04-13	Danisco Sweeteners Oy	Production of xylitol from a carbon source other than xylose and xylulose
WO2005113759A2 (en) *	2004-05-19	2005-12-01	Biotechnology Research And Development Corporation	Microbial production of xylitol via a hexose phosphate and a pentose phosphate intermediate
EP1766021B1 (de) *	2004-05-20	2012-05-09	AES Chemunex S.A.	Polynukleotide zum nachweis von escherichia coli o157:h7- und escherichia coli o157:nm-verotoxinproduzenten
KR101246780B1 (ko) *	2010-10-06	2013-03-26	한국과학기술원	아라비노스 대사경로가 도입된 자일리톨 생산균주 및 이를 이용한 자일리톨 생산방법
EP2957640B1 (de) *	2014-06-18	2018-03-14	Roquette Freres	Herstellung von Xylitol aus Glucose durch einen rekombinanten Stamm
WO2023220547A1 (en) *	2022-05-09	2023-11-16	Cargill, Incorporated	Genetically modified yeast and fermentation processes for the production of polyols

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS514279B1 (de) *	1970-05-26	1976-02-10
US4008285A (en) *	1974-04-22	1977-02-15	Melaja Asko J	Process for making xylitol
US4075406A (en) *	1974-04-22	1978-02-21	Suomen Sokeri Osakeyhtio	Process for making xylose
US4066711A (en) *	1976-03-15	1978-01-03	Suomen Sokeri Osakeyhtio (Finnish Sugar Company)	Method for recovering xylitol
DE4009676A1 (de) *	1990-03-26	1991-10-02	Rhein Biotech Proz & Prod Gmbh	Dna-sequenz, umfassend ein fuer xylosereduktase und/oder xylitoldehydrogenase codierendes strukturgen
FI901771A7 (fi) *	1990-04-06	1991-10-07	Valtion Teknillinen	Anvaendning av xylos hos hybridjaest.

1993
- 1993-11-05 AT AT93924615T patent/ATE184917T1/de not_active IP Right Cessation
- 1993-11-05 PL PL93308742A patent/PL178040B1/pl unknown
- 1993-11-05 RU RU95113172A patent/RU2142999C1/ru active
- 1993-11-05 HU HU9501288A patent/HU219016B/hu not_active IP Right Cessation
- 1993-11-05 BR BR9307391-7A patent/BR9307391A/pt not_active Application Discontinuation
- 1993-11-05 KR KR1019950701792A patent/KR950704503A/ko not_active Ceased
- 1993-11-05 AU AU54215/94A patent/AU5421594A/en not_active Abandoned
- 1993-11-05 ES ES93924615T patent/ES2139024T3/es not_active Expired - Lifetime
- 1993-11-05 NZ NZ257561A patent/NZ257561A/en unknown
- 1993-11-05 CA CA002148622A patent/CA2148622A1/en not_active Abandoned
- 1993-11-05 WO PCT/FI1993/000450 patent/WO1994010325A1/en not_active Ceased
- 1993-11-05 JP JP51074894A patent/JP3433295B2/ja not_active Expired - Fee Related
- 1993-11-05 DE DE69326559T patent/DE69326559T2/de not_active Expired - Lifetime
1995
- 1995-05-04 FI FI952148A patent/FI108300B/fi not_active IP Right Cessation
- 1995-05-04 NO NO951747A patent/NO951747L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
FI108300B (fi)	2001-12-31
WO1994010325A1 (en)	1994-05-11
CA2148622A1 (en)	1994-05-11
FI952148L (fi)	1995-07-04
HUT72187A (en)	1996-03-28
DE69326559T2 (de)	2000-02-10
KR950704503A (ko)	1995-11-20
NZ257561A (en)	1996-09-25
FI952148A0 (fi)	1995-05-04
RU2142999C1 (ru)	1999-12-20
JPH08505522A (ja)	1996-06-18
JP3433295B2 (ja)	2003-08-04
NO951747L (no)	1995-07-05
BR9307391A (pt)	1999-08-31
ATE184917T1 (de)	1999-10-15
NO951747D0 (no)	1995-05-04
DE69326559D1 (de)	1999-10-28
AU5421594A (en)	1994-05-24
ES2139024T3 (es)	2000-02-01
HU219016B (hu)	2001-01-29
PL308742A1 (en)	1995-08-21
RU95113172A (ru)	1997-03-27
HU9501288D0 (en)	1995-06-28

Publication	Publication Date	Title
EP0672161B1 (de)	1999-09-22	Rekombinante methode und wirt zur herstellung von xylitol
PL178040B1 (pl)	2000-02-29	Sposób wytwarzania ksylitolu i zrekombinowany gospodarz drobnoustrojowy
US20060110810A1 (en)	2006-05-25	Methods and materials for the synthesis of organic products
KR20110011675A (ko)	2011-02-08	4 탄소 알코올의 생산을 위해 개선된 효모 균주
KR102281701B1 (ko)	2021-07-23	아세토인을 제조하는 방법
KR102303832B1 (ko)	2021-09-17	내산성을 갖는 효모 세포, 상기 효모 세포를 제조하는 방법 및 이의 용도
EP3455362A1 (de)	2019-03-20	Mutante hefestämme mit erhöhter produktion von erythritol oder erythrulose
US6723540B1 (en)	2004-04-20	Manufacture of xylitol using recombinant microbial hosts
Yoshimoto et al.	1999	Isolation and characterization of the ATF2 gene encoding alcohol acetyltransferase II in the bottom fermenting yeast Saccharomyces pastorianus
BR112021011629A2 (pt)	2021-09-08	Via de coprodução de derivados de 3-hp e acetil-coa a partir de malonato semialdeído
CA2881407A1 (en)	2014-02-27	Production of fermentation products
KR102384227B1 (ko)	2022-04-07	Nadph 생성이 증가된 유전적으로 조작된 효모 세포, 효모 세포 중 nadph 수준을 증가시키는 방법, 상기 효모 세포를 제조하는 방법 및 상기 효모 세포를 이용하여 락테이트를 생산하는 방법
US5786186A (en)	1998-07-28	DNA encoding enzymes of the glycolytic pathway for use in alcohol producing yeast
Rønnow et al.	1999	Derepression of galactose metabolism in melibiase producing bakers’ and distillers’ yeast
Wenzel et al.	1993	Regulation of the PDA1 gene encoding the E1α subunit of the pyruvate dehydrogenase complex from Saccharomyces cerevisiae
JPWO2005085415A1 (ja)	2007-12-13	新規形質転換体およびそれを用いたポリエステルの製造方法
Papendieck et al.	2002	Technical enzyme production and whole-cell biocatalysis: application of Hansenula polymorpha
CN101652482A (zh)	2010-02-17	由代谢工程化酵母进行的丁醇生产
WO2013115959A1 (en)	2013-08-08	Methods and compositions for growth of yeast on alginate
Yasui et al.	1989	Existence and expression of photoreactivation repair genes in various yeast species
Klein et al.	1995	The Candida species: biochemistry, molecular biology and industrial applications
JP2007504813A (ja)	2007-03-08	Ｎａｄｈ依存型ｌ−キシルロース還元酵素
Ford et al.	1993	Physical and functional characterization of the cloned lysl+ gene of Schizosaccharomyces pombe
JPWO2003085111A1 (ja)	2005-08-11	新規プロモーター
Yoon et al.	1989	Cloning and Expression of the Structural Gene for Alcohol Dehydrogenase of Zymomonas mobilis in Escherichia coli