JPH02240024A - 活性型ビタミンｄ↓３類製剤用組成物 - Google Patents

活性型ビタミンｄ↓３類製剤用組成物

Info

Publication number
JPH02240024A
JPH02240024A JP1060554A JP6055489A JPH02240024A JP H02240024 A JPH02240024 A JP H02240024A JP 1060554 A JP1060554 A JP 1060554A JP 6055489 A JP6055489 A JP 6055489A JP H02240024 A JPH02240024 A JP H02240024A
Authority
JP
Japan
Prior art keywords
composition
active type
type vitamin
active vitamin
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1060554A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0587050B2 (2
Inventor
Masami Moroi
諸井　政己
Toshio Yokoyama
俊夫 横山
Akira Iwasa
岩佐　曜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SSP Co Ltd
Original Assignee
SSP Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SSP Co Ltd filed Critical SSP Co Ltd
Priority to JP1060554A priority Critical patent/JPH02240024A/ja
Priority to CA002011943A priority patent/CA2011943A1/en
Priority to KR1019900003246A priority patent/KR900013964A/ko
Priority to EP90104750A priority patent/EP0387808B1/en
Priority to ES90104750T priority patent/ES2057225T3/es
Priority to DE9090104750T priority patent/DE69001573T2/de
Publication of JPH02240024A publication Critical patent/JPH02240024A/ja
Priority to US08/003,689 priority patent/US5258375A/en
Publication of JPH0587050B2 publication Critical patent/JPH0587050B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP1060554A 1989-03-13 1989-03-13 活性型ビタミンｄ↓３類製剤用組成物 Granted JPH02240024A (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP1060554A JPH02240024A (ja) 1989-03-13 1989-03-13 活性型ビタミンｄ↓３類製剤用組成物
CA002011943A CA2011943A1 (en) 1989-03-13 1990-03-12 Compositions for the preparation of dosage-form active vitamins d3 and process for preparing stable dosage-form active vitamins d3 by using the same
KR1019900003246A KR900013964A (ko) 1989-03-13 1990-03-12 활성형 비타민 d₃류 제제용 조성물 및 이를 함유하는 안정한 활성형 비타민 d₃류 제제의 제조방법
EP90104750A EP0387808B1 (en) 1989-03-13 1990-03-13 Compositions for the preparation of dosage-form active vitamins d3 and process for preparing stable dosage-form active vitamins d3 by using the same
ES90104750T ES2057225T3 (es) 1989-03-13 1990-03-13 Una composicion para la preparacion de una vitamina d3 activa en forma de dosificacion y su procedimiento de preparacion.
DE9090104750T DE69001573T2 (de) 1989-03-13 1990-03-13 Zusammensetzungen zur herstellung von in dosisformen aktiven vitaminen d3 sowie verfahren zur herstellung stabiler, in dosisformen aktiver vitamine d3 unter deren verwendung.
US08/003,689 US5258375A (en) 1989-03-13 1993-01-13 Composition for the preparation of dosage-form active vitamins D3 containing polyvinylacetal diethylaminoacetate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1060554A JPH02240024A (ja) 1989-03-13 1989-03-13 活性型ビタミンｄ↓３類製剤用組成物

Publications (2)

Publication Number Publication Date
JPH02240024A true JPH02240024A (ja) 1990-09-25
JPH0587050B2 JPH0587050B2 (2) 1993-12-15

Family

ID=13145623

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1060554A Granted JPH02240024A (ja) 1989-03-13 1989-03-13 活性型ビタミンｄ↓３類製剤用組成物

Country Status (6)

Country Link
EP (1) EP0387808B1 (2)
JP (1) JPH02240024A (2)
KR (1) KR900013964A (2)
CA (1) CA2011943A1 (2)
DE (1) DE69001573T2 (2)
ES (1) ES2057225T3 (2)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008072532A1 (ja) * 2006-12-07 2008-06-19 Daiichi Sankyo Company, Limited 貯蔵安定性が改善された医薬組成物
US9034860B2 (en) 2006-12-07 2015-05-19 Daiichi Sankyo Company, Limited Pharmaceutical composition containing low-substituted hydroxypropyl cellulose
JP2017178932A (ja) * 2016-03-23 2017-10-05 株式会社ファンケル ビタミンｄ３安定化組成物
JP2018080168A (ja) * 2016-11-10 2018-05-24 日産化学工業株式会社 ビタミンｄ３誘導体の製剤
WO2018124260A1 (ja) * 2016-12-28 2018-07-05 中外製薬株式会社 Ｅｄ－７１の固体分散体および油分分散体を含む医薬組成物

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2845342B2 (ja) * 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
JPH04198129A (ja) * 1990-11-28 1992-07-17 Sumitomo Pharmaceut Co Ltd 活性型ビタミンｄ↓３類含有組成物
IL103224A (en) * 1992-09-18 1998-08-16 Teva Pharma Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3
PT3095447T (pt) 2006-02-03 2022-01-24 Opko Renal Llc Tratamento da insuficiência e deficiência de vitamina d com 25-hidroxivitamina d2 e 25-hidroxivitamina d3
DK2037936T3 (da) 2006-06-21 2014-09-22 Opko Renal Llc Fremgangsmåde til behandling og forebyggelse af sekundær hyperparathyroidisme
CA2683628C (en) 2007-04-25 2018-03-06 Cytochroma Inc. Method of treating vitamin d insufficiency and deficiency
ES3047207T3 (en) 2007-04-25 2025-12-03 Opko Renal Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
KR101691876B1 (ko) 2007-04-25 2017-01-02 사이토크로마 인코포레이티드 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
ES2593356T3 (es) 2008-04-02 2016-12-07 Opko Ireland Global Holdings, Ltd. Métodos, composiciones, usos y kits útiles para la deficiencia de la vitamina D y trastornos relacionados
US11672809B2 (en) 2010-03-29 2023-06-13 Eirgen Pharma Ltd. Methods and compositions for reducing parathyroid levels
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
KR20180123100A (ko) 2016-03-28 2018-11-14 옵코 아일랜드 글로벌 홀딩스 리미티드 비타민 d 치료 방법
GB202016614D0 (en) 2020-10-20 2020-12-02 King S College London Compounds

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6425723A (en) * 1988-07-07 1989-01-27 Teijin Ltd Production of active type vitamin d3 composition
JPS6483019A (en) * 1987-09-25 1989-03-28 Sunstar Inc Composition used in oral cavity for orthodontic therapy of tooth
JPH02229115A (ja) * 1989-03-01 1990-09-11 Teijin Ltd 安定性の改良された活性型ビタミンｄ↓３類固型製剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62149619A (ja) * 1985-09-05 1987-07-03 Teijin Ltd 活性型ビタミンｄ３類注射用組成物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6483019A (en) * 1987-09-25 1989-03-28 Sunstar Inc Composition used in oral cavity for orthodontic therapy of tooth
JPS6425723A (en) * 1988-07-07 1989-01-27 Teijin Ltd Production of active type vitamin d3 composition
JPH02229115A (ja) * 1989-03-01 1990-09-11 Teijin Ltd 安定性の改良された活性型ビタミンｄ↓３類固型製剤

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008072532A1 (ja) * 2006-12-07 2008-06-19 Daiichi Sankyo Company, Limited 貯蔵安定性が改善された医薬組成物
JPWO2008072532A1 (ja) * 2006-12-07 2010-03-25 第一三共株式会社 貯蔵安定性が改善された医薬組成物
US9034860B2 (en) 2006-12-07 2015-05-19 Daiichi Sankyo Company, Limited Pharmaceutical composition containing low-substituted hydroxypropyl cellulose
JP2017178932A (ja) * 2016-03-23 2017-10-05 株式会社ファンケル ビタミンｄ３安定化組成物
JP2018080168A (ja) * 2016-11-10 2018-05-24 日産化学工業株式会社 ビタミンｄ３誘導体の製剤
WO2018124260A1 (ja) * 2016-12-28 2018-07-05 中外製薬株式会社 Ｅｄ－７１の固体分散体および油分分散体を含む医薬組成物
CN110121348A (zh) * 2016-12-28 2019-08-13 中外制药株式会社 包含ed－71的固体分散体及油分散体的药物组合物
JPWO2018124260A1 (ja) * 2016-12-28 2019-10-31 中外製薬株式会社 Ｅｄ−７１の固体分散体および油分分散体を含む医薬組成物

Also Published As

Publication number Publication date
DE69001573T2 (de) 1993-08-26
CA2011943A1 (en) 1990-09-13
KR900013964A (ko) 1990-10-22
EP0387808A3 (en) 1991-04-03
ES2057225T3 (es) 1994-10-16
EP0387808B1 (en) 1993-05-12
EP0387808A2 (en) 1990-09-19
JPH0587050B2 (2) 1993-12-15
DE69001573D1 (de) 1993-06-17

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