JPH03504494A - Ｉｇｆ結合タンパク質、ｉｇｆ結合タンパク質をコードするｄｎａ構造体及びこのｄｎａ構造体を含有したベクター - Google Patents

Ｉｇｆ結合タンパク質、ｉｇｆ結合タンパク質をコードするｄｎａ構造体及びこのｄｎａ構造体を含有したベクター

Info

Publication number
JPH03504494A
JPH03504494A JP1503492A JP50349289A JPH03504494A JP H03504494 A JPH03504494 A JP H03504494A JP 1503492 A JP1503492 A JP 1503492A JP 50349289 A JP50349289 A JP 50349289A JP H03504494 A JPH03504494 A JP H03504494A
Authority
JP
Japan
Prior art keywords
igf
binding protein
ibp
binding
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1503492A
Other languages
English (en)
Japanese (ja)
Inventor
ドロップ，ステンワルト　レオナルド　セバスチャン
ブリンクマン，アレンド
Original Assignee
エラスムス、ユニベルシテイト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エラスムス、ユニベルシテイト filed Critical エラスムス、ユニベルシテイト
Publication of JPH03504494A publication Critical patent/JPH03504494A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP1503492A 1988-03-11 1989-03-10 Ｉｇｆ結合タンパク質、ｉｇｆ結合タンパク質をコードするｄｎａ構造体及びこのｄｎａ構造体を含有したベクター Pending JPH03504494A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK131988A DK131988A (da) 1988-03-11 1988-03-11 Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
DK1319/88 1988-03-11

Publications (1)

Publication Number Publication Date
JPH03504494A true JPH03504494A (ja) 1991-10-03

Family

ID=8103523

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1503492A Pending JPH03504494A (ja) 1988-03-11 1989-03-10 Ｉｇｆ結合タンパク質、ｉｇｆ結合タンパク質をコードするｄｎａ構造体及びこのｄｎａ構造体を含有したベクター

Country Status (5)

Country Link
EP (1) EP0404812A1 (da)
JP (1) JPH03504494A (da)
AU (1) AU3296589A (da)
DK (1) DK131988A (da)
WO (1) WO1989008667A1 (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03504597A (ja) * 1988-04-12 1991-10-09 シナージェン，インコーポレーテッド インスリン様成長因子活性の強化および阻害方法

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973115A (en) * 1987-05-15 1999-10-26 Amgen Inc. Method for potentiating and inhibiting insulin-like growth factor activity
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
US5324820A (en) * 1988-07-15 1994-06-28 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
CA1341598C (en) * 1988-07-15 2009-09-29 Central Sydney Area Health Service Acid-labile sub-unit (als) of insulin-like growth factor binding proteincomplex
US6465423B1 (en) 1988-07-15 2002-10-15 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
GB8826451D0 (en) * 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
US5212074A (en) * 1990-08-28 1993-05-18 Chiron Corporation Genetic material encoding new insulin-like growth factor binding protein igfbp-6
DE69132814T2 (de) * 1990-08-28 2002-06-13 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5
PT98803B (pt) * 1990-08-28 1999-01-29 Chiron Corp Processo de preparacao de uma proteina de ligacao purificada
US6326154B1 (en) 1990-11-19 2001-12-04 Genentech, Inc. Ligand-mediated immunofunctional hormone binding protein assay method
US5210017A (en) * 1990-11-19 1993-05-11 Genentech, Inc. Ligand-mediated immunofunctional hormone binding protein assay method
DE69233155T2 (de) 1991-01-08 2004-06-03 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Insulinartigen wachstumsfaktor bindendes protein
US5198340A (en) * 1991-01-17 1993-03-30 Genentech, Inc. Assay for free igf-i, igf-ii, and gh levels in body fluids
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
US6420172B1 (en) 1992-04-20 2002-07-16 Tib Company, Llc Method for inducing tumor immunity
US5407913A (en) * 1992-12-03 1995-04-18 Celtrix Pharmaceuticals, Inc. Method and composition for systemic treatment of tissue injury
AU686585B2 (en) 1992-11-04 1998-02-12 Dennis L Andress Truncated insulin-like growth factor binding proteins having mitogenic activity
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
CN1134111A (zh) * 1993-04-07 1996-10-23 赛纳根公司 使用胰岛素样生长因子结合蛋白质的方法
CA2168790A1 (en) * 1993-08-03 1995-02-09 Christopher A. Maack Method of treating reproductive disorders
US7026299B2 (en) 1994-07-12 2006-04-11 Human Genome Sciences, Inc. Connective tissue growth factor-2
AU689492B2 (en) 1994-07-12 1998-04-02 Human Genome Sciences, Inc. Connective tissue growth factor-2
EP0800530A4 (en) * 1994-07-20 1998-12-02 Celtrix Pharma IGF / IGFBP COMPLEX FOR PROMOTING BONE TRAINING AND REGULATING BONE REMODELING
US5747280A (en) * 1995-06-05 1998-05-05 Human Genome Sciences, Inc. Human vascular IBP-like growth factor
US5994302A (en) * 1994-12-09 1999-11-30 Human Genome Sciences, Inc. Human vascular IBP-like growth factor
US20030069177A1 (en) 2000-05-16 2003-04-10 Genentech, Inc. Method for treating cartilage disorders
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
DE60042550D1 (de) 1999-01-06 2009-08-27 Genentech Inc Mutierte varianten des insulin-ähnlichen wachstumsfaktor i (igf-i)
CA2356109C (en) 1999-01-06 2008-04-22 Genentech, Inc. Insulin-like growth factor (igf) i mutant variants
US7071300B2 (en) 2001-03-14 2006-07-04 Genentech, Inc. IGF antagonist peptides
DK2274978T3 (da) 2003-09-12 2015-06-15 Ipsen Biopharmaceuticals Inc Fremgangsmåder til behandling af en insulin-lignende vækstfaktor-I(IGF-I)-mangel
EP1670822A2 (en) 2003-10-03 2006-06-21 Genentech, Inc. Igf binding proteins
KR20200097679A (ko) 2017-09-11 2020-08-19 샤이어 휴먼 지네틱 테라피즈 인크. 만성 폐 질환 치료를 위한 방법 및 조성물
ES3005966T3 (en) 2020-10-19 2025-03-17 Oak Hill Bio Ltd Compositions suitable for use in neonates
JP2025502349A (ja) 2022-01-19 2025-01-24 オーク ヒル バイオ リミテッド Ｉｇｆ－１／ｉｇｆｂｐの酸化を低減するための組成物および方法
WO2023242442A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Method of maturing/differentiating neurons and/or modulating the vagus nerve
WO2023242439A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Vascular stabilisation (preterm infants)
WO2023242440A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
IL322721A (en) 2023-02-14 2025-10-01 Oak Hill Bio Ltd Treatment of healing dysregulation in digestive tract tissue

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3338480A1 (de) * 1983-10-22 1985-05-02 Behringwerke Ag, 3550 Marburg Neues protein pp(pfeil abwaerts)2(pfeil abwaerts)(pfeil abwaerts)0(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03504597A (ja) * 1988-04-12 1991-10-09 シナージェン，インコーポレーテッド インスリン様成長因子活性の強化および阻害方法

Also Published As

Publication number Publication date
DK131988D0 (da) 1988-03-11
WO1989008667A1 (en) 1989-09-21
DK131988A (da) 1989-09-12
AU3296589A (en) 1989-10-05
EP0404812A1 (en) 1991-01-02

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