JPH056530B2 - - Google Patents

Info

Publication number: JPH056530B2
Authority: JP; Japan
Prior art keywords: solvent; present; add; water; substance
Prior art date: 1988-12-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP63333031A

Other languages

English (en)

Japanese (ja)

Other versions

JPH02178231A (ja

Inventor

Saburo Hirai

Zenichi Ogita

Hiroshi Kamikawa

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

KOKANDO KK

Original Assignee

KOKANDO KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-27

Filing date

1988-12-27

Publication date

1993-01-26

1988-12-27 Application filed by KOKANDO KK filed Critical KOKANDO KK

1988-12-27 Priority to JP63333031A priority Critical patent/JPH02178231A/ja

1990-07-11 Publication of JPH02178231A publication Critical patent/JPH02178231A/ja

1993-01-26 Publication of JPH056530B2 publication Critical patent/JPH056530B2/ja

Status Granted legal-status Critical Current

Links

239000002904 solvent Substances 0.000 claims description 20
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
238000000034 method Methods 0.000 claims description 4
239000000284 extract Substances 0.000 claims description 3
238000000746 purification Methods 0.000 claims 1
239000000126 substance Substances 0.000 description 10
239000003814 drug Substances 0.000 description 8
229940079593 drug Drugs 0.000 description 5
210000002784 stomach Anatomy 0.000 description 5
LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 4
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
229940093265 berberine Drugs 0.000 description 3
QISXPYZVZJBNDM-UHFFFAOYSA-N berberine Natural products COc1ccc2C=C3N(Cc2c1OC)C=Cc4cc5OCOc5cc34 QISXPYZVZJBNDM-UHFFFAOYSA-N 0.000 description 3
239000000287 crude extract Substances 0.000 description 3
238000000605 extraction Methods 0.000 description 3
238000010438 heat treatment Methods 0.000 description 3
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
208000025865 Ulcer Diseases 0.000 description 2
239000003699 antiulcer agent Substances 0.000 description 2
YBHILYKTIRIUTE-UHFFFAOYSA-N berberine Chemical compound C1=C2CC[N+]3=CC4=C(OC)C(OC)=CC=C4C=C3C2=CC2=C1OCO2 YBHILYKTIRIUTE-UHFFFAOYSA-N 0.000 description 2
150000003836 berberines Chemical class 0.000 description 2
230000002496 gastric effect Effects 0.000 description 2
ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
230000000144 pharmacologic effect Effects 0.000 description 2
231100000397 ulcer Toxicity 0.000 description 2
-1 Dimethyl prostaglandin E 2 Chemical compound 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
208000008469 Peptic Ulcer Diseases 0.000 description 1
241000700159 Rattus Species 0.000 description 1
150000001298 alcohols Chemical class 0.000 description 1
229930013930 alkaloid Natural products 0.000 description 1
150000001336 alkenes Chemical class 0.000 description 1
230000001142 anti-diarrhea Effects 0.000 description 1
230000003110 anti-inflammatory effect Effects 0.000 description 1
230000000767 anti-ulcer Effects 0.000 description 1
235000019658 bitter taste Nutrition 0.000 description 1
229940126678 chinese medicines Drugs 0.000 description 1
238000009826 distribution Methods 0.000 description 1
239000002552 dosage form Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000000762 glandular Effects 0.000 description 1
230000035876 healing Effects 0.000 description 1
230000023597 hemostasis Effects 0.000 description 1
241000411851 herbal medicine Species 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
210000000936 intestine Anatomy 0.000 description 1
231100000053 low toxicity Toxicity 0.000 description 1
238000009115 maintenance therapy Methods 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
208000011906 peptic ulcer disease Diseases 0.000 description 1
238000011403 purification operation Methods 0.000 description 1
239000002994 raw material Substances 0.000 description 1
238000010992 reflux Methods 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Landscapes

Compounds Of Unknown Constitution (AREA)
Medicines Containing Plant Substances (AREA)

JP63333031A 1988-12-27 1988-12-27 オウレンの分画精製法 Granted JPH02178231A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP63333031A JPH02178231A (ja)	1988-12-27	1988-12-27	オウレンの分画精製法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP63333031A JPH02178231A (ja)	1988-12-27	1988-12-27	オウレンの分画精製法

Publications (2)

Publication Number	Publication Date
JPH02178231A JPH02178231A (ja)	1990-07-11
JPH056530B2 true JPH056530B2 (da)	1993-01-26

Family

ID=18261496

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP63333031A Granted JPH02178231A (ja)	1988-12-27	1988-12-27	オウレンの分画精製法

Country Status (1)

Country	Link
JP (1)	JPH02178231A (da)

1988
- 1988-12-27 JP JP63333031A patent/JPH02178231A/ja active Granted

Also Published As

Publication number	Publication date
JPH02178231A (ja)	1990-07-11

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