JPH0643436B2 - 新規物質トレハロスタチンおよびその製造方法 - Google Patents

新規物質トレハロスタチンおよびその製造方法

Info

Publication number
JPH0643436B2
JPH0643436B2 JP2-503981A JP50398190A JPH0643436B2 JP H0643436 B2 JPH0643436 B2 JP H0643436B2 JP 50398190 A JP50398190 A JP 50398190A JP H0643436 B2 JPH0643436 B2 JP H0643436B2
Authority
JP
Japan
Prior art keywords
ppm
trehalostatin
amycolatopsis
trehalostatica
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2-503981A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO1990010010A1 (ja
JPH0643436B1 (de
Inventor
澤夫 村尾
隆志 新
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Priority to JP2-503981A priority Critical patent/JPH0643436B2/ja
Publication of JPWO1990010010A1 publication Critical patent/JPWO1990010010A1/ja
Publication of JPH0643436B1 publication Critical patent/JPH0643436B1/ja
Publication of JPH0643436B2 publication Critical patent/JPH0643436B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12R1/04

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
JP2-503981A 1989-02-28 1990-02-28 新規物質トレハロスタチンおよびその製造方法 Expired - Lifetime JPH0643436B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2-503981A JPH0643436B2 (ja) 1989-02-28 1990-02-28 新規物質トレハロスタチンおよびその製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1-45394 1989-02-28
JP4539489 1989-02-28
JP2-503981A JPH0643436B2 (ja) 1989-02-28 1990-02-28 新規物質トレハロスタチンおよびその製造方法

Publications (3)

Publication Number Publication Date
JPWO1990010010A1 JPWO1990010010A1 (ja) 1991-01-10
JPH0643436B1 JPH0643436B1 (de) 1994-06-08
JPH0643436B2 true JPH0643436B2 (ja) 1994-06-08

Family

ID=12718048

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2-503981A Expired - Lifetime JPH0643436B2 (ja) 1989-02-28 1990-02-28 新規物質トレハロスタチンおよびその製造方法

Country Status (9)

Country Link
US (2) US5169778A (de)
EP (1) EP0414914B1 (de)
JP (1) JPH0643436B2 (de)
AT (1) ATE105562T1 (de)
CA (1) CA2028117C (de)
DE (1) DE69008795T2 (de)
DK (1) DK0414914T3 (de)
ES (1) ES2052250T3 (de)
WO (1) WO1990010010A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE105562T1 (de) * 1989-02-28 1994-05-15 Suntory Ltd Trehalostatin und seine herstellung.
NO177589C (no) * 1991-02-15 1995-10-18 Sankyo Co Polyhydroksycyklopentanderivat
JPH05279374A (ja) * 1992-03-31 1993-10-26 Sawao Murao スイダトレスチン及びその製造方法
JPH0932942A (ja) * 1995-07-18 1997-02-07 F M Valve Seisakusho:Kk 逆止弁装置
IS6389A (is) * 2001-08-31 2003-03-03 Heraeus Kulzer Gmbh & Co. Kg Reynsla af sýklalyfjahúðun skrokka, sem í eru örholrými, og einnig af þannig húðuðum skrokkum og notkun þeirra
ATE549399T1 (de) 2006-12-13 2012-03-15 Dsm Sinochem Pharm Nl Bv Verfahren zur herstellung von pravastatin
CN116478880B (zh) * 2023-04-25 2024-12-06 昆明学院 一株图库曼拟无枝菌酸菌kc 316及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1544068A (en) * 1977-03-30 1979-04-11 Bayer Ag Amino-sugar derivatives
GB8700513D0 (en) * 1987-01-09 1987-02-11 Pfizer Ltd Antibiotics produced by fermentation
US4981799A (en) * 1987-08-21 1991-01-01 Takeda Chemical Industries, Ltd. Acylamino acid racemase, production and use thereof
ATE105562T1 (de) * 1989-02-28 1994-05-15 Suntory Ltd Trehalostatin und seine herstellung.

Also Published As

Publication number Publication date
CA2028117C (en) 2000-08-01
US5169778A (en) 1992-12-08
EP0414914B1 (de) 1994-05-11
DE69008795T2 (de) 1994-08-25
JPH0643436B1 (de) 1994-06-08
EP0414914A1 (de) 1991-03-06
CA2028117A1 (en) 1990-08-29
DK0414914T3 (da) 1994-07-04
WO1990010010A1 (en) 1990-09-07
DE69008795D1 (de) 1994-06-16
US5372816A (en) 1994-12-13
EP0414914A4 (en) 1991-07-24
ES2052250T3 (es) 1994-07-01
ATE105562T1 (de) 1994-05-15

Similar Documents

Publication Publication Date Title
KR930010705B1 (ko) Fr-900520 물질의 제조방법
US4487925A (en) Rebeccamycin and process for its preparation
JPH0566394B2 (de)
US4252898A (en) Antibiotics A6888C and A6888X
JPH0643436B2 (ja) 新規物質トレハロスタチンおよびその製造方法
EP0050724B1 (de) Herstellung von Anthracyclinglycosiden
EP0871638B1 (de) Aminooligosaccharid-derivate und verfahren zu ihrer herstellung
JPWO1990010010A1 (ja) 新規物質トレハロスタチンおよびその製造方法
US4358584A (en) Antibiotics A6888C and A6888X
US4292309A (en) Antibiotics C-14482 B1, B2 and B3
JP3048513B2 (ja) 2, 2’ −ビピリジン誘導体、その製造方法及び該誘導体を含有する抗腫瘍剤
US4686308A (en) Novel physiologically active substance MH435
US4835141A (en) Neutral macrolide antibiotics from Streptomyces
US5021549A (en) Physiologically active substances, probestin and prostatin and production thereof
JP3068700B2 (ja) 新規トレハゾリン誘導体およびその製造法
JP2592468B2 (ja) 新規抗生物質ベナノマイシンaおよびbならびにその製造法
JP3209791B2 (ja) オキサゾリン誘導体及びその製造法
JPH10114777A (ja) 抗生物質スピロキシマイシンとその製造法
JP3530563B2 (ja) Ko−8119物質及びその製造法
US4956283A (en) Process for preparing macrolide antibiotics by culturing streptomyces hirsutus ATCC 53513
US4310627A (en) Process of producing 3-trehalosamine by fermentation
KR0163660B1 (ko) 방선균류인 마이크로모노스포라 속 sa-246 균주를 이용한 항균-항암활성을 갖는 saph 유도체의 제조방법
EP0205981B1 (de) Antitumor- und Antimikroben-Verbindung, deren mikrobiologische Herstellung und deren Benutzung als Arzneimittel
JPH05279374A (ja) スイダトレスチン及びその製造方法
KR0122427B1 (ko) 아미노펩티데이스 m 저해물질, 그의 제조방법 및 그를 생성하는 미생물