JPH07146295A - ラマン分光測定による免疫分析方法及び装置 - Google Patents

ラマン分光測定による免疫分析方法及び装置

Info

Publication number: JPH07146295A
Authority: JP; Japan
Prior art keywords: light; cell; antigen; sample; colloid
Prior art date: 1993-11-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP5314587A

Other languages

English (en)

Japanese (ja)

Inventor

Giyoumei Tou

暁鳴竇

Toshio Takama

利夫高間

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Arkray Inc

Original Assignee

Kyoto Daiichi Kagaku KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-19

Filing date

1993-11-19

Publication date

1995-06-06

1993-11-19 Application filed by Kyoto Daiichi Kagaku KK filed Critical Kyoto Daiichi Kagaku KK

1993-11-19 Priority to JP5314587A priority Critical patent/JPH07146295A/ja

1994-11-10 Priority to DE69426642T priority patent/DE69426642T2/de

1994-11-10 Priority to EP94117767A priority patent/EP0654670B1/de

1994-11-14 Priority to US08/339,710 priority patent/US5607643A/en

1995-06-06 Publication of JPH07146295A publication Critical patent/JPH07146295A/ja

1996-11-21 Priority to US08/752,244 priority patent/US5869346A/en

Status Pending legal-status Critical Current

Links

238000001069 Raman spectroscopy Methods 0.000 title claims abstract description 37
238000005259 measurement Methods 0.000 title abstract description 24
230000003595 spectral effect Effects 0.000 title abstract description 4
238000000034 method Methods 0.000 title description 22
239000000084 colloidal system Substances 0.000 claims abstract description 25
230000005284 excitation Effects 0.000 claims abstract description 24
239000000126 substance Substances 0.000 claims abstract description 22
238000006243 chemical reaction Methods 0.000 claims abstract description 18
239000000427 antigen Substances 0.000 claims abstract description 17
102000036639 antigens Human genes 0.000 claims abstract description 17
108091007433 antigens Proteins 0.000 claims abstract description 17
238000003018 immunoassay Methods 0.000 claims description 24
229910000510 noble metal Inorganic materials 0.000 claims description 12
239000002245 particle Substances 0.000 claims description 10
238000000926 separation method Methods 0.000 claims description 8
230000001678 irradiating effect Effects 0.000 claims description 6
238000001816 cooling Methods 0.000 claims description 5
238000010438 heat treatment Methods 0.000 claims description 5
230000001900 immune effect Effects 0.000 claims description 5
238000001514 detection method Methods 0.000 claims description 4
230000003287 optical effect Effects 0.000 abstract description 19
238000001237 Raman spectrum Methods 0.000 abstract description 10
PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract description 9
229910052751 metal Inorganic materials 0.000 abstract description 8
239000002184 metal Substances 0.000 abstract description 8
238000002372 labelling Methods 0.000 abstract description 3
238000001228 spectrum Methods 0.000 description 8
230000004907 flux Effects 0.000 description 7
BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 4
238000004458 analytical method Methods 0.000 description 4
238000010586 diagram Methods 0.000 description 4
230000008105 immune reaction Effects 0.000 description 4
238000004445 quantitative analysis Methods 0.000 description 4
238000010521 absorption reaction Methods 0.000 description 3
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
238000000149 argon plasma sintering Methods 0.000 description 3
229910052737 gold Inorganic materials 0.000 description 3
239000010931 gold Substances 0.000 description 3
238000004020 luminiscence type Methods 0.000 description 3
238000005406 washing Methods 0.000 description 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
229910052782 aluminium Inorganic materials 0.000 description 2
229910001873 dinitrogen Inorganic materials 0.000 description 2
230000036046 immunoreaction Effects 0.000 description 2
150000002500 ions Chemical class 0.000 description 2
230000010355 oscillation Effects 0.000 description 2
102000004169 proteins and genes Human genes 0.000 description 2
108090000623 proteins and genes Proteins 0.000 description 2
230000035945 sensitivity Effects 0.000 description 2
229910052709 silver Inorganic materials 0.000 description 2
239000004332 silver Substances 0.000 description 2
230000002269 spontaneous effect Effects 0.000 description 2
239000013076 target substance Substances 0.000 description 2
238000001845 vibrational spectrum Methods 0.000 description 2
241000283707 Capra Species 0.000 description 1
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 description 1
230000002238 attenuated effect Effects 0.000 description 1
238000005452 bending Methods 0.000 description 1
239000000112 cooling gas Substances 0.000 description 1
229910052802 copper Inorganic materials 0.000 description 1
239000010949 copper Substances 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
238000004925 denaturation Methods 0.000 description 1
230000036425 denaturation Effects 0.000 description 1
238000009792 diffusion process Methods 0.000 description 1
239000003814 drug Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000001704 evaporation Methods 0.000 description 1
230000008020 evaporation Effects 0.000 description 1
238000000605 extraction Methods 0.000 description 1
239000011521 glass Substances 0.000 description 1
ZBKIUFWVEIBQRT-UHFFFAOYSA-N gold(1+) Chemical compound [Au+] ZBKIUFWVEIBQRT-UHFFFAOYSA-N 0.000 description 1
230000005484 gravity Effects 0.000 description 1
238000004848 nephelometry Methods 0.000 description 1
238000004451 qualitative analysis Methods 0.000 description 1
238000003908 quality control method Methods 0.000 description 1
239000010453 quartz Substances 0.000 description 1
230000000630 rising effect Effects 0.000 description 1
238000004611 spectroscopical analysis Methods 0.000 description 1
238000004879 turbidimetry Methods 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Pathology (AREA)
Urology & Nephrology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

JP5314587A 1993-11-19 1993-11-19 ラマン分光測定による免疫分析方法及び装置 Pending JPH07146295A (ja)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
JP5314587A JPH07146295A (ja)	1993-11-19	1993-11-19	ラマン分光測定による免疫分析方法及び装置
DE69426642T DE69426642T2 (de)	1993-11-19	1994-11-10	Verfahren und Vorrichtung zur Analyse der Immunität mit Ramanspektrometrie
EP94117767A EP0654670B1 (de)	1993-11-19	1994-11-10	Verfahren und Vorrichtung zur Analyse der Immunität mit Ramanspektrometrie
US08/339,710 US5607643A (en)	1993-11-19	1994-11-14	Method of and apparatus for analyzing immuity by RAMAN spectrometry
US08/752,244 US5869346A (en)	1993-11-19	1996-11-21	Method of and apparatus for analyzing immunity by raman spectrometry

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP5314587A JPH07146295A (ja)	1993-11-19	1993-11-19	ラマン分光測定による免疫分析方法及び装置

Publications (1)

Publication Number	Publication Date
JPH07146295A true JPH07146295A (ja)	1995-06-06

Family

ID=18055096

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP5314587A Pending JPH07146295A (ja)	1993-11-19	1993-11-19	ラマン分光測定による免疫分析方法及び装置

Country Status (4)

Country	Link
US (2)	US5607643A (de)
EP (1)	EP0654670B1 (de)
JP (1)	JPH07146295A (de)
DE (1)	DE69426642T2 (de)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH09171015A (ja) *	1995-10-18	1997-06-30	Kdk Corp	尿中成分測定装置
JP2003504642A (ja) *	1999-07-16	2003-02-04	ダブリューエム・マーシュ・ライス・ユニバーシティー	生体感知用途のための金属微細シェル
WO2010101209A1 (ja)	2009-03-04	2010-09-10	有限会社マイテック	表面増強ラマン散乱活性測定基板
US7829349B2 (en)	2006-04-25	2010-11-09	Canon Kabushiki Kaisha	Base carrier for detecting target substance, element for detecting target substance, method for detecting target substance using the element, and kit for detecting target substance
WO2012033097A1 (ja) *	2010-09-06	2012-03-15	有限会社マイテック	金属錯体量子結晶の製造方法
JP2012106242A (ja) *	1997-02-28	2012-06-07	Cepheid	熱交換を行ない光学的に検出する化学反応アセンブリ
DE102015225871A1 (de) *	2015-12-18	2017-06-22	Carl Zeiss Microscopy Gmbh	Verfahren der Stimulierten Raman-Mikroskopie und Mikroskop
TWI891308B (zh) *	2020-06-18	2025-07-21	德商卡爾蔡司Ｓｍｔ有限公司	用於特徵化微影光罩的設備和方法
JP7756407B1 (ja) *	2024-11-20	2025-10-20	シンバイオ製薬株式会社	イムノアッセイ方法及びイムノアッセイ装置

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07227299A (ja) *	1994-02-14	1995-08-29	Kyoto Daiichi Kagaku:Kk	Ｄｎａの特定塩基配列の検出方法及びその装置
US5750410A (en) *	1994-08-26	1998-05-12	Kyoto Dai-Ichi Kagaku Co., Ltd.	Method of and apparatus for immune analysis
JP3436982B2 (ja) *	1994-08-03	2003-08-18	アークレイ株式会社	免疫測定方法及びその装置
DE69525226T2 (de) *	1994-11-25	2002-06-27	Kyoto Daiichi Kagaku Co. Ltd., Kyoto	Vorrichtung und Verfahren zur Bestimmung von Wasserstoffperoxid
US5828450A (en) *	1995-07-19	1998-10-27	Kyoto Dai-Ichi Kagaku Co., Ltd.	Spectral measuring apparatus and automatic analyzer
US6887430B1 (en)	1996-01-26	2005-05-03	Kyoto Dai-Ichi Kagaku Co., Ltd.	Apparatus for immune analysis
CN1122181C (zh) *	1996-03-11	2003-09-24	株式会社京都第一科学	用于免疫分析的方法及装置
US5866430A (en) *	1996-06-13	1999-02-02	Grow; Ann E.	Raman optrode processes and devices for detection of chemicals and microorganisms
US6558956B1 (en)	1997-06-24	2003-05-06	The University Of Wyoming	Method and apparatus for detection of a controlled substance
DE19729352A1 (de) *	1997-07-09	1999-01-14	Basf Ag	Zentrifugierverfahren zur Probencharakterisierung
GB9804083D0 (en)	1998-02-26	1998-04-22	Univ Strathclyde	Immunoassays
WO1999044045A1 (en) *	1998-02-27	1999-09-02	Massachusetts Institute Of Technology	Single molecule detection with surface-enhanced raman scattering and applications in dna or rna sequencing
US6770488B1 (en)	1999-03-19	2004-08-03	The University Of Wyoming	Practical method and apparatus for analyte detection with colloidal particles
US6081328A (en) *	1999-07-20	2000-06-27	International Business Machines Corporation	Enhancement of raman scattering intensity of thin film contaminants on substrates
US6967717B1 (en) *	2000-06-14	2005-11-22	The United States Of America As Represented By The Secretary Of The Navy	Thermo-electrically cooled surface enhanced Raman spectroscopy sensor system
US20030017620A1 (en) *	2001-06-21	2003-01-23	Carron Keith T.	Lyophilization of colloidal metals for surface enhanced Raman scattering
JPWO2003093835A1 (ja) *	2002-04-30	2005-09-08	アークレイ株式会社	分析用具の温調方法、および温調機能を備えた分析装置
WO2006096468A2 (en) *	2005-03-03	2006-09-14	Sword Diagnostics, Inc.	Enhanced detection of biological and bioactive components by resonance raman spectroscopy
US8663575B2 (en) *	2005-08-19	2014-03-04	Canadian Blood Services	Sample holder for dynamic light scattering
US7842247B2 (en)	2005-08-19	2010-11-30	Canadian Blood Services	Sample holder for dynamic light scattering
JP4810304B2 (ja) *	2006-05-12	2011-11-09	キヤノン株式会社	化学センサ素子及びその製造方法
US8039272B2 (en)	2009-04-01	2011-10-18	Nova Biomedical	Rapid quantification assay involving concentrated and ligand-coated gold colloid
CN103278491B (zh) *	2009-11-25	2017-07-07	欧普图斯(苏州)光学纳米科技有限公司	用基于纳米结构的光谱检测方法检测化学物和生化物杂质
US8696991B1 (en)	2010-01-04	2014-04-15	Harold W. Howe	Field deployable surface plasmon resonance based biosensor
WO2012012258A2 (en) *	2010-07-21	2012-01-26	First Solar, Inc.	Temperature-adjusted spectrometer
EP2893320B1 (de) *	2012-08-20	2020-12-23	Siemens Healthcare Diagnostics Inc.	Zweischaliges luminometer
WO2014121134A2 (en) *	2013-02-01	2014-08-07	State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University	Embodiments of a composition comprising diatom frustules and a method for making and using
CN104535553A (zh) *	2014-12-26	2015-04-22	杭州霆科生物科技有限公司	一种用于拉曼光谱的流动电解池
WO2016133991A1 (en)	2015-02-17	2016-08-25	Xylem Ip Uk Sarl	Technique for temperature controlling polarimeter sample cells
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CN116359200A (zh) *	2023-03-01	2023-06-30	深圳大学	一种双金属纳米硅藻壳的拉曼传感器的构建方法及肌氨酸检测方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1583216A (de) *	1968-04-26	1969-10-24
GB1375834A (de) *	1970-12-09	1974-11-27
US4053229A (en) *	1976-01-13	1977-10-11	The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration	2°/90° Laboratory scattering photometer
US4213703A (en) *	1978-05-30	1980-07-22	Beckman Instruments, Inc.	Photometer with stationary sample holder and rotatable shutter
JPS57118143A (en) *	1981-01-14	1982-07-22	Hitachi Ltd	Laser raman spectrochemical apparatus for removing fluorescence
US5241363A (en) *	1989-07-10	1993-08-31	General Atomics	Micropipette adaptor with temperature control for PCR amplification
US5092674A (en) *	1989-07-10	1992-03-03	General Atomics	Micropipette adaptor for spectrophotometers with temperature control
US5037200A (en) *	1989-07-11	1991-08-06	Tosoh Corporation	Laser-operated detector
WO1991006894A1 (en) *	1989-10-18	1991-05-16	Research Corporation Technologies, Inc.	Plasmon enhanced photo processes
US5266498A (en) *	1989-10-27	1993-11-30	Abbott Laboratories	Ligand binding assay for an analyte using surface-enhanced scattering (SERS) signal
US5376556A (en) *	1989-10-27	1994-12-27	Abbott Laboratories	Surface-enhanced Raman spectroscopy immunoassay
JPH0472549A (ja) *	1990-07-13	1992-03-06	Mitsubishi Electric Corp	燃料性状検出装置
DE4223840C2 (de) *	1992-07-20	1994-06-16	Zeiss Carl Jena Gmbh	Refraktometer
JP3343156B2 (ja) *	1993-07-14	2002-11-11	アークレイ株式会社	光学式成分濃度測定装置および方法

1993
- 1993-11-19 JP JP5314587A patent/JPH07146295A/ja active Pending
1994
- 1994-11-10 DE DE69426642T patent/DE69426642T2/de not_active Expired - Fee Related
- 1994-11-10 EP EP94117767A patent/EP0654670B1/de not_active Expired - Lifetime
- 1994-11-14 US US08/339,710 patent/US5607643A/en not_active Expired - Lifetime
1996
- 1996-11-21 US US08/752,244 patent/US5869346A/en not_active Expired - Fee Related

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH09171015A (ja) *	1995-10-18	1997-06-30	Kdk Corp	尿中成分測定装置
JP2012106242A (ja) *	1997-02-28	2012-06-07	Cepheid	熱交換を行ない光学的に検出する化学反応アセンブリ
JP2003504642A (ja) *	1999-07-16	2003-02-04	ダブリューエム・マーシュ・ライス・ユニバーシティー	生体感知用途のための金属微細シェル
US7829349B2 (en)	2006-04-25	2010-11-09	Canon Kabushiki Kaisha	Base carrier for detecting target substance, element for detecting target substance, method for detecting target substance using the element, and kit for detecting target substance
JP5466226B2 (ja) *	2009-03-04	2014-04-09	有限会社マイテック	表面増強ラマン散乱活性測定基板
WO2010101209A1 (ja)	2009-03-04	2010-09-10	有限会社マイテック	表面増強ラマン散乱活性測定基板
US9658163B2 (en)	2009-03-04	2017-05-23	Mytech Co., Ltd.	Assaying substrate with surface-enhanced raman scattering activity
WO2012033097A1 (ja) *	2010-09-06	2012-03-15	有限会社マイテック	金属錯体量子結晶の製造方法
US9139907B2 (en)	2010-09-06	2015-09-22	Mytech Co., Ltd	Method for producing metal complex quantum crystals
JP5964234B2 (ja) *	2010-09-06	2016-08-03	有限会社マイテック	金属錯体量子結晶の製造方法
JP2016197114A (ja) *	2010-09-06	2016-11-24	有限会社マイテック	量子結晶基板
DE102015225871A1 (de) *	2015-12-18	2017-06-22	Carl Zeiss Microscopy Gmbh	Verfahren der Stimulierten Raman-Mikroskopie und Mikroskop
DE102015225871B4 (de) *	2015-12-18	2017-07-27	Carl Zeiss Microscopy Gmbh	Verfahren der Stimulierten Raman-Mikroskopie und Mikroskop
TWI891308B (zh) *	2020-06-18	2025-07-21	德商卡爾蔡司Ｓｍｔ有限公司	用於特徵化微影光罩的設備和方法
JP7756407B1 (ja) *	2024-11-20	2025-10-20	シンバイオ製薬株式会社	イムノアッセイ方法及びイムノアッセイ装置

Also Published As

Publication number	Publication date
US5607643A (en)	1997-03-04
EP0654670B1 (de)	2001-01-31
DE69426642T2 (de)	2001-08-02
EP0654670A3 (de)	1995-10-18
EP0654670A2 (de)	1995-05-24
DE69426642D1 (de)	2001-03-08
US5869346A (en)	1999-02-09

Publication	Publication Date	Title
JPH07146295A (ja)	1995-06-06	ラマン分光測定による免疫分析方法及び装置
US5750410A (en)	1998-05-12	Method of and apparatus for immune analysis
Penner	2017	Ultraviolet, visible, and fluorescence spectroscopy
US5828450A (en)	1998-10-27	Spectral measuring apparatus and automatic analyzer
RU2223479C2 (ru)	2004-02-10	Способ и устройство для анализа изотопсодержащих молекул по спектру поглощения
US4486272A (en)	1984-12-04	Method of electrochemical measurement utilizing photochemical reaction and apparatus therefor
JPH0252980B2 (de)	1990-11-15
KR19980035472A (ko)	1998-08-05	웨이퍼 표면분석 장치 및 이를 이용한 웨이퍼 표면 분석방법
JP3436982B2 (ja)	2003-08-18	免疫測定方法及びその装置
US6887430B1 (en)	2005-05-03	Apparatus for immune analysis
JP2001194297A (ja)	2001-07-19	環境測定方法及び装置
JP2001311697A (ja)	2001-11-09	表面状態測定方法及び装置
JPH07198600A (ja)	1995-08-01	フーリエ変換多成分連続吸光分析計
US5032730A (en)	1991-07-16	Immunoassay apparatus
JPH0875651A (ja)	1996-03-22	レーザ発光分光分析方法
JPS63140941A (ja)	1988-06-13	赤外線ガス分析計
USH922H (en)	1991-05-07	Method for analyzing materials using x-ray fluorescence
JPH0514219B2 (de)	1993-02-24
JPS6058826B2 (ja)	1985-12-21	ネフエロメトリ−法
JPH09251004A (ja)	1997-09-22	光音響分析方法およびその装置
JPH0549177B2 (de)	1993-07-23
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