JPH08169829A - 血圧降下のための製薬学的組成物及びその製法 - Google Patents

血圧降下のための製薬学的組成物及びその製法

Info

Publication number
JPH08169829A
JPH08169829A JP7185275A JP18527595A JPH08169829A JP H08169829 A JPH08169829 A JP H08169829A JP 7185275 A JP7185275 A JP 7185275A JP 18527595 A JP18527595 A JP 18527595A JP H08169829 A JPH08169829 A JP H08169829A
Authority
JP
Japan
Prior art keywords
weight
nifedipine
solution
blood pressure
ethyl oleate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7185275A
Other languages
English (en)
Japanese (ja)
Inventor
Margit Nagy
ナヂ マルギット
Csaba Farsang
ファルシャング チャバ
Lidia Fedina
フェディナ リーディア
Katalin Szemeredi
セメレーディ カタリン
Gabor Szenasi
セーナーシィ ガーボル
Janos Egri
エグリ ヤーノシュ
Antal Mosonyi
モショニュイ アンタル
Borbala Barta
バルタ ボルバーラ
Toth Gizella
トート ギゼラ
Ibolya Nyaradi
ニャーラーディ イボリャ
Frigyes Gorgenyi
ゲルゲーニュイ フリヂェシュ
Zsuzsa Orr
オルル ヂュヂャ
Geza Floris
フローリシュ ゲーザ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of JPH08169829A publication Critical patent/JPH08169829A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
JP7185275A 1994-07-26 1995-07-21 血圧降下のための製薬学的組成物及びその製法 Pending JPH08169829A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9402193A HU214582B (hu) 1994-07-26 1994-07-26 Porlasztható, vérnyomáscsökkentő hatású gyógyszerkészítmény és eljárás előállítására
HU9402193 1994-07-26

Publications (1)

Publication Number Publication Date
JPH08169829A true JPH08169829A (ja) 1996-07-02

Family

ID=10985460

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7185275A Pending JPH08169829A (ja) 1994-07-26 1995-07-21 血圧降下のための製薬学的組成物及びその製法

Country Status (18)

Country Link
JP (1) JPH08169829A (de)
AT (1) AT402690B (de)
AU (1) AU699386B2 (de)
BE (1) BE1011413A4 (de)
CZ (1) CZ286399B6 (de)
DE (1) DE19527140A1 (de)
EE (1) EE9500029A (de)
FR (1) FR2722988B1 (de)
GB (1) GB2291593B (de)
HR (1) HRP950374A2 (de)
HU (1) HU214582B (de)
IT (1) IT1277348B1 (de)
LT (1) LT4042B (de)
LV (1) LV11026B (de)
PL (1) PL181069B1 (de)
SK (1) SK280463B6 (de)
UA (1) UA39880C2 (de)
YU (1) YU50795A (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008530233A (ja) * 2005-02-17 2008-08-07 ベルセラ ファーマシューティカルズ 動物における障害を治療および予防するための薬剤組成物の経粘膜投与

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7632517B2 (en) 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
WO1999016417A1 (en) * 1997-10-01 1999-04-08 Flemington Pharmaceutical Corporation Buccal, polar and non-polar spray or capsule
DE102006027794A1 (de) * 2006-06-16 2007-12-20 Lts Lohmann Therapie-Systeme Ag Antihypertonie-Kombinationswafer
FR2906140B1 (fr) * 2006-09-22 2008-12-05 Philippe Perovitch Forme galenique pour l'administration par voie trans-muqueuse de principes actifs

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307422A1 (de) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen
EP0175671A1 (de) 1984-08-23 1986-03-26 Kuhlemann & Co. Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
ATE71520T1 (de) * 1986-03-10 1992-02-15 Burghart Kurt Pharmazeutische zubereitung sowie verfahren zur herstellung derselben.
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
DE3779999T2 (de) * 1986-11-14 1992-12-10 Theratech Inc Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.
JPS63170316A (ja) * 1986-12-30 1988-07-14 Fujimoto Seiyaku Kk ニフエジピン経皮吸収外用製剤
DE3714402A1 (de) * 1987-04-30 1988-11-10 Kali Chemie Pharma Gmbh Arzneimittelformulierung
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
AT391269B (de) * 1988-12-30 1990-09-10 Burghart Kurt Pharmazeutische zubereitung
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation
HU205249B (en) * 1990-11-09 1992-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing suspensive aerosole composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008530233A (ja) * 2005-02-17 2008-08-07 ベルセラ ファーマシューティカルズ 動物における障害を治療および予防するための薬剤組成物の経粘膜投与
US8940271B2 (en) 2005-02-17 2015-01-27 Abbott Laboratories Transmucosal administration of drug compositions for treating and preventing disorders in animals

Also Published As

Publication number Publication date
ITMI951621A0 (it) 1995-07-26
EE9500029A (et) 1996-02-15
LT4042B (en) 1996-09-25
PL309757A1 (en) 1996-02-05
DE19527140A1 (de) 1996-02-01
CZ181195A3 (en) 1996-02-14
CZ286399B6 (en) 2000-04-12
FR2722988A1 (fr) 1996-02-02
SK280463B6 (sk) 2000-02-14
HUT75457A (en) 1997-05-28
AU699386B2 (en) 1998-12-03
GB2291593A (en) 1996-01-31
YU50795A (sh) 1998-05-15
IT1277348B1 (it) 1997-11-10
LV11026B (en) 1996-04-20
PL181069B1 (pl) 2001-05-31
GB9515205D0 (en) 1995-09-20
ITMI951621A1 (it) 1997-01-26
HU214582B (hu) 1998-04-28
BE1011413A4 (fr) 1999-09-07
ATA121495A (de) 1996-12-15
LV11026A (lv) 1996-02-20
HRP950374A2 (en) 1997-10-31
SK92295A3 (en) 1996-05-08
UA39880C2 (uk) 2001-07-16
HU9402193D0 (en) 1994-09-28
AU2326995A (en) 1996-02-08
LT95084A (en) 1996-06-25
GB2291593B (en) 1998-03-11
FR2722988B1 (fr) 1999-10-08
AT402690B (de) 1997-07-25

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