JPH09507829A - 増殖分化因子−８ - Google Patents

増殖分化因子−８

Info

Publication number
JPH09507829A
JPH09507829A JP6521293A JP52129394A JPH09507829A JP H09507829 A JPH09507829 A JP H09507829A JP 6521293 A JP6521293 A JP 6521293A JP 52129394 A JP52129394 A JP 52129394A JP H09507829 A JPH09507829 A JP H09507829A
Authority
JP
Japan
Prior art keywords
gdf
antibody
sequence
cells
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6521293A
Other languages
English (en)
Japanese (ja)
Inventor
リー，セ−ジン
シー． マックフェロン，アレクサンドラ
Original Assignee
ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン filed Critical ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン
Publication of JPH09507829A publication Critical patent/JPH09507829A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP6521293A 1993-03-19 1994-03-18 増殖分化因子−８ Pending JPH09507829A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3392393A 1993-03-19 1993-03-19
US08/033,923 1993-03-19
PCT/US1994/003019 WO1994021681A1 (fr) 1993-03-19 1994-03-18 Facteur gde8 de differentiation de croissance

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2004001012A Division JP2004121265A (ja) 1993-03-19 2004-01-06 増殖分化因子−８

Publications (1)

Publication Number Publication Date
JPH09507829A true JPH09507829A (ja) 1997-08-12

Family

ID=21873232

Family Applications (4)

Application Number Title Priority Date Filing Date
JP6521293A Pending JPH09507829A (ja) 1993-03-19 1994-03-18 増殖分化因子−８
JP2004001012A Pending JP2004121265A (ja) 1993-03-19 2004-01-06 増殖分化因子−８
JP2005326630A Pending JP2006117682A (ja) 1993-03-19 2005-11-10 増殖分化因子−８
JP2007125060A Pending JP2007306920A (ja) 1993-03-19 2007-05-09 増殖分化因子−８

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2004001012A Pending JP2004121265A (ja) 1993-03-19 2004-01-06 増殖分化因子−８
JP2005326630A Pending JP2006117682A (ja) 1993-03-19 2005-11-10 増殖分化因子−８
JP2007125060A Pending JP2007306920A (ja) 1993-03-19 2007-05-09 増殖分化因子−８

Country Status (8)

Country Link
US (5) US5827733A (fr)
EP (2) EP0690873B1 (fr)
JP (4) JPH09507829A (fr)
CA (1) CA2157577C (fr)
DE (1) DE69432815T2 (fr)
DK (1) DK0690873T3 (fr)
ES (1) ES2201076T3 (fr)
WO (1) WO1994021681A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004504826A (ja) * 2000-07-27 2004-02-19 ザ　ジョーンズ　ホプキンス　ユニバーシティー　スクール　オブ　メディシン プロミオスタチンペプチドおよびその使用法
JP2007535912A (ja) * 2003-12-31 2007-12-13 シェーリング−プラウ・リミテッド 中和エピトープベースの増殖増強性ワクチン

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* Cited by examiner, † Cited by third party
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CA2157577A1 (fr) 1994-09-29
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US6096506A (en) 2000-08-01
US7179884B2 (en) 2007-02-20
US5827733A (en) 1998-10-27
EP0690873A1 (fr) 1996-01-10
CA2157577C (fr) 2009-11-17
EP1333035A3 (fr) 2004-07-07
US20030120058A1 (en) 2003-06-26
DE69432815D1 (de) 2003-07-17
US7534432B2 (en) 2009-05-19
EP0690873B1 (fr) 2003-06-11
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US20070185321A1 (en) 2007-08-09
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