JPH10287651A5 - - Google Patents
Info
- Publication number
- JPH10287651A5 JPH10287651A5 JP1998107161A JP10716198A JPH10287651A5 JP H10287651 A5 JPH10287651 A5 JP H10287651A5 JP 1998107161 A JP1998107161 A JP 1998107161A JP 10716198 A JP10716198 A JP 10716198A JP H10287651 A5 JPH10287651 A5 JP H10287651A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- fluorine
- cooh
- coor11
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19713865 | 1997-04-04 | ||
| DE19713865:9 | 1998-01-26 | ||
| DE19802530:0 | 1998-01-26 | ||
| DE1998102530 DE19802530A1 (de) | 1998-01-26 | 1998-01-26 | Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH10287651A JPH10287651A (ja) | 1998-10-27 |
| JPH10287651A5 true JPH10287651A5 (2) | 2005-09-08 |
| JP4234805B2 JP4234805B2 (ja) | 2009-03-04 |
Family
ID=26035472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10716198A Expired - Fee Related JP4234805B2 (ja) | 1997-04-04 | 1998-04-03 | プロパノールアミン誘導体、それらの製法、それらを含有する薬剤およびそれらの使用 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5874451A (2) |
| EP (1) | EP0869121B1 (2) |
| JP (1) | JP4234805B2 (2) |
| KR (1) | KR19980081055A (2) |
| CN (1) | CN1185217C (2) |
| AR (1) | AR011210A1 (2) |
| AT (1) | ATE268758T1 (2) |
| AU (1) | AU730228B2 (2) |
| BR (1) | BR9801150A (2) |
| CA (1) | CA2233925A1 (2) |
| CZ (1) | CZ293758B6 (2) |
| DE (1) | DE59811528D1 (2) |
| DK (1) | DK0869121T3 (2) |
| ES (1) | ES2223091T3 (2) |
| HU (1) | HUP9800781A3 (2) |
| ID (1) | ID20137A (2) |
| IL (1) | IL123927A (2) |
| MY (1) | MY114944A (2) |
| NZ (1) | NZ330110A (2) |
| PL (1) | PL325699A1 (2) |
| PT (1) | PT869121E (2) |
| RU (1) | RU2198876C2 (2) |
| TR (1) | TR199800608A2 (2) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19845402B4 (de) * | 1998-10-02 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| KR100581199B1 (ko) | 1998-06-19 | 2006-05-17 | 카이론 코포레이션 | 글리코겐 신타제 키나제 3의 억제제 |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| DE19845406C2 (de) * | 1998-10-02 | 2001-10-18 | Aventis Pharma Gmbh | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| DE19845403B4 (de) * | 1998-10-02 | 2005-02-10 | Aventis Pharma Deutschland Gmbh | Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| DE19845405C2 (de) * | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
| AU2002231688A1 (en) | 2000-12-21 | 2002-07-01 | Sanofi-Aventis Deutschland Gmbh | Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use |
| PL366855A1 (en) * | 2001-08-22 | 2005-02-07 | Aventis Pharma Deutschland Gmbh | Combination preparations of aryl substituted propanolamine derivatives with other active ingredients and the use thereof |
| JP4691988B2 (ja) | 2002-10-03 | 2011-06-01 | 小野薬品工業株式会社 | Ｌｐａ受容体拮抗剤 |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| ATE528276T1 (de) * | 2003-12-19 | 2011-10-15 | Ono Pharmaceutical Co | Lysophosphatidylsäurerezeptor-antagonistische verbindungen und ihre anwendungen |
| CN1869002A (zh) * | 2005-05-27 | 2006-11-29 | 中国科学院上海药物研究所 | 一类非甾体雄激素受体调节剂、其制备方法和用途 |
| DK2848610T3 (da) * | 2006-11-15 | 2017-11-06 | Ym Biosciences Australia Pty | Hæmmere af kinaseaktivitet |
| EP2575821B1 (en) | 2010-05-26 | 2015-08-12 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
| CN104023727B (zh) | 2011-10-28 | 2017-04-05 | 鲁美纳医药公司 | 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂 |
| CA2852957C (en) | 2011-10-28 | 2020-08-04 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease |
| CN105228615A (zh) | 2013-03-15 | 2016-01-06 | 鲁美纳医药公司 | 用于治疗巴雷特食管和胃食管返流疾病的胆汁酸再循环抑制剂 |
| US20140275090A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease |
| CN105553262B (zh) * | 2015-08-24 | 2018-02-16 | 苏州瑞铬优电子科技有限公司 | 一种提高dc/dc升压变换器转换效率的方法 |
| PL3923943T3 (pl) | 2019-02-12 | 2024-12-09 | Mirum Pharmaceuticals, Inc. | Zależna od genotypu i dawki odpowiedź na asbti u pacjentów z niedoborem pompy eksportu soli żółciowych |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI892341A7 (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanoliamiinijohdannaisia |
| NZ240846A (en) * | 1990-12-06 | 1994-04-27 | Hoechst Ag | Dimeric bile acid derivatives; preparatory processes and pharmaceutical compositions |
| DE4040026A1 (de) * | 1990-12-14 | 1992-06-17 | Bayer Ag | Substituierte pyridyl-dihydroxy-heptensaeure und deren salze |
| GB9203347D0 (en) * | 1992-02-17 | 1992-04-01 | Wellcome Found | Hypolipidaemic compounds |
| DK0557879T3 (da) * | 1992-02-22 | 1997-06-16 | Hoechst Ag | 4-amino-2-ureido-pyrimidin-5-carboxylsyreamider, fremgangsmåde til deres fremstilling, lægemidler med indhold af disse forbindelser og deres anvendelse |
-
1998
- 1998-03-24 DK DK98105256T patent/DK0869121T3/da active
- 1998-03-24 DE DE59811528T patent/DE59811528D1/de not_active Expired - Lifetime
- 1998-03-24 PT PT98105256T patent/PT869121E/pt unknown
- 1998-03-24 EP EP98105256A patent/EP0869121B1/de not_active Expired - Lifetime
- 1998-03-24 AT AT98105256T patent/ATE268758T1/de not_active IP Right Cessation
- 1998-03-24 ES ES98105256T patent/ES2223091T3/es not_active Expired - Lifetime
- 1998-04-02 TR TR1998/00608A patent/TR199800608A2/xx unknown
- 1998-04-02 US US09/053,513 patent/US5874451A/en not_active Expired - Lifetime
- 1998-04-02 NZ NZ330110A patent/NZ330110A/xx unknown
- 1998-04-02 IL IL12392798A patent/IL123927A/xx active IP Right Grant
- 1998-04-02 ID IDP980494A patent/ID20137A/id unknown
- 1998-04-02 AR ARP980101512A patent/AR011210A1/es unknown
- 1998-04-03 JP JP10716198A patent/JP4234805B2/ja not_active Expired - Fee Related
- 1998-04-03 HU HU9800781A patent/HUP9800781A3/hu unknown
- 1998-04-03 CZ CZ19981025A patent/CZ293758B6/cs not_active IP Right Cessation
- 1998-04-03 CA CA002233925A patent/CA2233925A1/en not_active Abandoned
- 1998-04-03 MY MYPI98001488A patent/MY114944A/en unknown
- 1998-04-03 KR KR1019980011750A patent/KR19980081055A/ko not_active Abandoned
- 1998-04-03 RU RU98106112/04A patent/RU2198876C2/ru not_active IP Right Cessation
- 1998-04-03 CN CNB981082521A patent/CN1185217C/zh not_active Expired - Fee Related
- 1998-04-03 PL PL98325699A patent/PL325699A1/xx not_active Application Discontinuation
- 1998-04-03 AU AU60624/98A patent/AU730228B2/en not_active Ceased
- 1998-04-06 BR BR9801150A patent/BR9801150A/pt not_active IP Right Cessation
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