JPH11506739A5 - - Google Patents

Info

Publication number
JPH11506739A5
JPH11506739A5 JP1997500833A JP50083397A JPH11506739A5 JP H11506739 A5 JPH11506739 A5 JP H11506739A5 JP 1997500833 A JP1997500833 A JP 1997500833A JP 50083397 A JP50083397 A JP 50083397A JP H11506739 A5 JPH11506739 A5 JP H11506739A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997500833A
Other languages
English (en)
Japanese (ja)
Other versions
JP3962430B2 (ja
JPH11506739A (ja
Filing date
Publication date
Priority claimed from US08/484,545 external-priority patent/US5631347A/en
Application filed filed Critical
Publication of JPH11506739A publication Critical patent/JPH11506739A/ja
Publication of JPH11506739A5 publication Critical patent/JPH11506739A5/ja
Application granted granted Critical
Publication of JP3962430B2 publication Critical patent/JP3962430B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50083397A 1995-06-07 1996-06-04 脂肪酸アシル化蛋白質のゲル化削減法 Expired - Fee Related JP3962430B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/484,545 US5631347A (en) 1995-06-07 1995-06-07 Reducing gelation of a fatty acid-acylated protein
US08/484,545 1995-06-07
PCT/US1996/007965 WO1996040188A1 (en) 1995-06-07 1996-06-04 Reducing gelation of a fatty acid-acylated protein

Publications (3)

Publication Number Publication Date
JPH11506739A JPH11506739A (ja) 1999-06-15
JPH11506739A5 true JPH11506739A5 (2) 2004-07-22
JP3962430B2 JP3962430B2 (ja) 2007-08-22

Family

ID=23924602

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50083397A Expired - Fee Related JP3962430B2 (ja) 1995-06-07 1996-06-04 脂肪酸アシル化蛋白質のゲル化削減法

Country Status (10)

Country Link
US (1) US5631347A (2)
EP (1) EP0747390B1 (2)
JP (1) JP3962430B2 (2)
AT (1) ATE264867T1 (2)
AU (1) AU5951596A (2)
CA (1) CA2223531A1 (2)
DE (1) DE69632224T2 (2)
DK (1) DK0747390T3 (2)
ES (1) ES2218569T3 (2)
WO (1) WO1996040188A1 (2)

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US6858580B2 (en) * 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6835802B2 (en) * 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6828305B2 (en) * 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
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US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
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US7196059B2 (en) * 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7312192B2 (en) * 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7166571B2 (en) * 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US6913903B2 (en) * 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
WO2003105768A2 (en) 2002-06-13 2003-12-24 Nobex Corporation Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
EP1633391B1 (en) 2003-06-03 2011-10-19 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
KR101308912B1 (ko) 2003-06-03 2013-09-23 노보 노르디스크 에이/에스 안정화된 약학적 펩티드 조성물
KR101243648B1 (ko) 2003-11-20 2013-03-14 노보 노르디스크 에이/에스 제조 및 주사 장치용에 최적인 프로필렌 글리콜 함유펩티드 제제
CN101027318B (zh) 2004-07-19 2016-05-25 比奥孔有限公司 胰岛素-低聚物共轭物，制剂及其用途
JP4965446B2 (ja) 2004-08-31 2012-07-04 ノヴォ ノルディスク アー／エス ペプチド、ポリペプチド及びタンパク質の安定化のためのトリス（ヒドロキシメチル）アミノメタンの使用
RU2413530C9 (ru) 2004-11-12 2021-05-18 Ново Нордиск А/С Стабильные препараты инсулинотропных пептидов
BRPI0710503A2 (pt) * 2006-04-07 2011-08-16 Merrion Res Iii Ltd uso de uma composição farmacêutica, composição farmacêutica, e, forma de dosagem oral
WO2007146234A2 (en) * 2006-06-09 2007-12-21 Merrion Research Ii Limited Solid oral dosage form containing an enhancer
US9241908B2 (en) * 2007-10-16 2016-01-26 Biocon Limited Orally administrable solid pharmaceutical composition and a process thereof
US20090280169A1 (en) * 2008-05-07 2009-11-12 Merrion Research Iii Limited Compositions of peptides and processes of preparation thereof
TWI480286B (zh) * 2009-02-25 2015-04-11 Merrion Res Iii Ltd 雙膦酸鹽類組合物及藥物遞送
CN102770152B (zh) 2009-11-25 2016-07-06 阿瑞斯根股份有限公司 肽类的粘膜递送
US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
US9089484B2 (en) * 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
EP2661273A4 (en) 2011-01-07 2014-06-04 Merrion Res Iii Ltd IRON PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
JP7211704B2 (ja) 2015-01-29 2023-01-24 ノヴォ ノルディスク アー／エス Ｇｌｐ－１アゴニスト及び腸溶コーティングを含む錠剤
WO2018157150A1 (en) 2017-02-27 2018-08-30 Duke University In vivo protein n-acylation
BR112020002804A2 (pt) 2017-08-24 2020-07-28 Novo Nordisk A/S composição farmacêutica líquida, e, kit
IL294521A (en) 2020-02-18 2022-09-01 Novo Nordisk As glp-1 compounds and their uses

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